What is refractory cancer and how is it treated?
Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment.
What is the meaning of refractory?
2 a : resistant to treatment or cure a refractory lesion b : unresponsive to stimulus c : immune, insusceptible after recovery they were refractory to infection 3 : difficult to fuse, corrode, or draw out especially : capable of enduring high temperature
What is conservative treatment?
Conservative Treatment Definition. Conservative management is an approach to treating back pain, neck pain and related spinal conditions utilizing non-surgical treatment options, such as physical therapy, medication and injections.
What happens when a patient’s disease becomes refractory?
When a patient’s disease is or becomes refractory, the next step may be to try another form of treatment — called a second- or third-line treatment — or to enroll the patient in a clinical trial.
What does conservative treatment mean in medical terms?
Conservative management is a type of medical treatment defined by the avoidance of invasive measures such as surgery or other invasive procedures, usually with the intent to preserve function or body parts.
What does it mean to be refractory to a treatment?
Listen to pronunciation. (reh-FRAK-tor-ee) In medicine, describes a disease or condition that does not respond to treatment.
What are conservative methods of treatment?
Conservative therapies are all non-invasive procedures, i.e., all therapies that do not involve surgery. Conservative procedures usually involve little or no pain and low risk and are therefore performed without anesthesia/sedation.
What does conservative surgery mean?
An operation that is the least aggressive, often most tissue-conserving therapy for a condition—e.g., lumpectomy rather than mastectomy for localized breast cancer.
What does refractory mean in oncology?
Listen to pronunciation. (reh-FRAK-tor-ee KAN-ser) Cancer that does not respond to treatment. The cancer may be resistant at the beginning of treatment or it may become resistant during treatment.
What does refractory mean in cardiology?
The refractoriness of a cardiac tissue can be defined by the response of that tissue to the introduction of premature stimuli. The effective refractory period (ERP) of a cardiac tissue is the longest interval of the input into a part of the conduction system that fails to propagate through that tissue.
When is conservative treatment used?
Conservative care is a variety of non-surgical treatments used to manage neck or back conditions. Depending on your condition, you may receive one or more of these treatments: Physical therapy. Massage therapy.
What is the conservative approach?
The Conservative approach is a risk-free strategy of working capital financing. A company adopting this strategy maintains a higher level of current assets and, therefore, higher working capital. The long-term sources of funds, such as equity, debentures, term loans, etc., finance the major part of the working capital.
What is considered conservative treatment for back pain?
Conservative treatments do not require surgery. Conservative treatments for back pain may include medications, injections or physical therapy. Non- surgical treatments require less downtime from everyday life and are considered by many patients to be a more practical pain management technique.
What is failed conservative treatment?
Failure of conservative treatment was defined as the persistence or aggravation of symptoms and signs, increasing aneurysmal dilation, or new appearance of a dissecting aneurysm after treatment. Patients in whom conservative treatment failed were considered candidates for endovascular stenting as second line treatment.
What is conservative treatment of appendicitis?
Interventions: The conservative treatment arm underwent intravenous cefotaxime 1 g twice daily and metronidazole for at least 24 hours. Patients who improved were discharged 24 hours later with oral ciprofloxacin 500 mg twice a day and metronidazole 400 mg three times a day for 10 days.
What are the types of breast-conserving surgery?
Breast-conserving surgery is sometimes called lumpectomy, quadrantectomy, partial mastectomy, or segmental mastectomy depending on how much tissue is removed.
What is refractory cancer?
Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment. “We would consider disease refractory if doesn’t respond at all or responds but starts to grow in a very short time frame,” explains Ann LaCasce, MD, MMSc, a physician in the Adult Lymphoma Program at Dana-Farber ...
What does "refractory" mean in medical terms?
Medically Reviewed By: Ann S. LaCasce, MD, MMSc. The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment.
What is the next step in a patient's treatment?
When a patient’s disease is or becomes refractory, the next step may be to try another form of treatment — called a second- or third-line treatment — or to enroll the patient in a clinical trial.
What is conservative management?
Conservative management is an approach to treating back pain, neck pain and related spinal conditions utilizing non-surgical treatment options , such as physical therapy, medication and injections.
How to treat back pain?
Most episodes of back pain can be treated through conservative care and a combination of several conservative treatments is often recommended to alleviate pain and rehabilitate the lower back. If a condition requires emergency care, conservative management may be passed up for surgical intervention.
Why is it important to define refractory symptom?
The importance of defining a refractory symptom is central in utilizing palliative sedation in a safe, efficacious, and ethical manner. A refractory symptom is one that cannot be adequately controlled despite aggressive efforts to identify a tolerable therapy that does not compromise consciousness ( Cherny 1994 ).
Which tumors are most likely to cause refractory symptoms?
The malignant tumors most often associated with refractory symptoms include those in the lungs, gastrointestinal tract, head and neck, colon, rectum, and breasts, though certainly any malignancy can cause refractory symptoms.
What is treatment resistant?
Essentially, it’s a medical name that is given to a condition that has not responded to treatment, be that medication, counseling, or other forms of talking therapies. The term “treatment-resistant” is sometimes used to describe the same circumstances.
Is it important to talk to your doctor about alternative therapies?
Of course, it’s always important to talk to your doctor if you want to try alternative therapies, but it does exemplify the fact that medical science tends to work quite slowly – and many treatment-refractory cases are just waiting for developments to catch up.
Is CBD a treatment refractory condition?
In many cases, treatment-refractory conditions are merely waiting for new, innovative approaches that may not have yet entered the mainstream. CBD, for example, has shown great benefits for mental health, but has existed outside of standard medical practice; those who wished to try CBD opted to buy Harmony CBD for themselves.
Is mental health treatment effective?
This is incredibly difficult to deal with; after all, when we become unwell, most of us expect modern medicine to be able to offer a cure. Mental health, however, doesn’ t work like that.
Is treatment refractory permanent?
If, however, your condition is found to be treatment-refractory, try to focus on the fact that this is not necessarily permanent, that effective treatment may well be available in future, and work with medical professionals to ensure you can manage as well as possible in the meantime.
Can treatment refractory mental health be temporary?
There is also the fact that many cases of treatment-refractory mental health conditions are simply not responding to conventional approaches right now – but they will in the future, often for no obvious reason. treatment- refractory status can be temporary; it does not mean that your condition will never improve.
How much does refractory save?
And yet, it has been proven that when properly designed and installed, refractory can save up to five to seven percent of fuel costs (oil, gas, coal, or refuse).
Why is failure of refractory material complex?
Discovering why a refractory material fails is a complex problem because failure is not caused by just one factor, but rather a combination of the following factors: The material selected does not match the environment that exists (i.e., reducing atmosphere);
What elements can react with refractory materials?
In the presence of moisture, sulfur also could form sulfurous and sulfuric acids, which could react with the basic components of a refractory material. Alkali such as sodium (Na) and potassium (K) can chemically react with silica found in some refractory materials.
What should be examined for signs that may indicate the root cause of the failure?
The existing material (or the lack thereof) should be examined for signs that may indicate the root cause of the failure. When looking at an existing refractory lining or photos of the existing lining, keep in mind the following questions:
Can refractory material be used after mixing?
This could reduce the strength of the installed material. Every refractory material has a pot life, which designates how long a mixed refractory material can be used after mixing. Failure to follow recommended pot life times could result in a refractory material not reaching its proper strength.