how much more effecitve is treatment of periodondal disease with a dna saliva test

by Melissa Gleichner Published 3 years ago Updated 2 years ago

Genetic presymptomatic testing complements bacterial DNA testing by providing insight into the patient's genetic predisposition to periodontal disease before symptoms appear, or when disease is already present. DNA-PCR testing of saliva can help the clinician provide an earlier and more specific diagnosis of disease based on causation.

Full Answer

Can saliva be used as a diagnostic tool for periodontal disease?

Get Healthy Teeth And Gums At Mandeville Center of Dental Excellence. ‍. If you suspect that you or a loved one has gum disease, we can help! Give us a call at (985) 626-4401 and Dr. Schof and our dental team will provide you with comprehensive, personalized dental care. Back to Blog.

How do you test for periodontal disease?

The oral bacterial DNA test, also known as a saliva test, identifies the pathogens causing periodontal problems. This allows the dentist to approach the soft tissue with an effective antibiotic. The test also alerts doctors to current oral diseases, as well as predicting future issues. The test is used pre-therapy to establish a baseline of the ...

How does periodontal disease affect the antioxidant capacity of saliva?

DNA-PCR testing of saliva can help the clinician provide an earlier and more specific diagnosis of disease based on causation. Treatment planning is also enhanced, as therapy can be appropriately modified based on both clinical and biological inflammatory factors. Finally, patient communication and case acceptance can be more readily achieved ...

What is a self-administered home test for periodontal disease?

Even though the diagnostic value of saliva has been recognized and several potential biomarkers of periodontal diseases identified, most of the work conducted to date came short of providing clinically reliable and useful information for practitioners in terms of developing a more precise periodontal diagnosis and subsequent treatment planning ...

Are saliva genetic tests accurate?

The saliva samples contain a significantly lower percentage of amplifiable human DNA (37.3%) when compared with blood samples.Mar 20, 2012

Does genetics play a role in periodontal disease?

Current studies suggest that periodontal disease is influenced by heredity, so your genetic makeup truly does have the potential to make you more susceptible to periodontitis. Aggressive Periodontitis is a condition where patients rapidly lose bone around selected teeth.

How effective is periodontal treatment?

Periodontal therapies and treatments are often exceptionally effective, and as long as you follow the instructions your dentist provides you during the maintenance stage, your risk of recurrence is low. This includes careful oral hygiene and no use of any tobacco products.

What percentage of risk is genetic for periodontal disease?

Recent clinical research has demonstrated that the Heritability Estimate for clinical signs of periodontal disease probably ranges between 40 and 80 percent.Dec 31, 1999

Can periodontitis be reversed?

Periodontitis can't be reversed, only slowed down, while gingivitis can be reversed. This is why it's important to catch it in its early stages and prevent it from moving on to periodontitis.Sep 18, 2019

Is periodontal disease curable?

Periodontitis can only be treated but cannot be cured. Gingivitis, on the other hand, can be prevented by maintaining proper oral hygiene practices and visiting the dentist for checkups and exams.

How much is treatment for periodontitis?

Periodontal Disease treatment cost ranges from $1,700 - $8,000, and teeth extractions average $200.00-$300.00 per tooth. The first treatment option is root scaling and planning. If this is not effective, surgery is needed, potentially using pocket reduction and bone grafting.Jan 20, 2021

How long does periodontal treatment take?

Most gum surgery procedures take around 2 hours to complete. In some cases, the surgery will require a person to be asleep or partially asleep during the procedure. Other times, the surgery only involves the use of a local anesthetic to numb the gums. The injection of the numbing medication can be mildly uncomfortable.Mar 10, 2018

How do you fix advanced gum disease?

If you have advanced periodontitis, treatment may require dental surgery, such as: Flap surgery (pocket reduction surgery). Your periodontist makes tiny incisions in your gum so that a section of gum tissue can be lifted back, exposing the roots for more effective scaling and root planing.Feb 14, 2020

Can losing teeth hereditary?

According to research, about 60 percent of tooth decay appears to involve genetic factors. While it's still a relatively new area of study, it is becoming more evident that tooth decay and genetics are closely related in several essential ways.

Can receding gums be genetic?

There are several possible culprits behind receding gums, but genetics are definitely among the possible causes. In fact, research indicates that about 30 percent of people are genetically susceptible to periodontal (gum) disease, which can cause gum recession.Sep 17, 2017

Is aggressive periodontitis genetic?

Association studies and the familial aggregation of aggressive periodontitis suggest a significant genetic component in the increased predisposition to this disease. There is evidence to support the contribution of a few major genes or of multiple small-effects genes.

What is the most common disease in humans?

Gingivitis and periodontitis are chronic inflammatory conditions that may affect as much as 80% of the adult population, making them one of the most prevalent diseases in humankind.1, 2The disease process is initiated by the accumulation of bacteria along the gingival margin and in the interface between the gingival tissues and the teeth.

Is gingivitis a reversible condition?

The clinical condition is termed gingivitis, which is associated neither with apical migration of the junctional epithelium nor with destruction of bone and periodontal ligament fibers. Gingivitis is a reversible condition that can usually be treated with professional biofilm removal and improvement in oral hygiene.

What is the color of gingivitis?

Inflamed gingival tissues often appear swollen with rolled borders, which are present with soft textures and redness (as opposed to pink) in color.

Why is saliva important for periodontal disease?

Saliva, as a mirror of oral and systemic health, is a valuable source for clinically relevant information because it contains biomarkers specific for the unique physiologic aspects of periodontal diseases. This review highlights the various potentials of saliva as a diagnostic biomarker for periodontal diseases.

Why is early diagnosis important?

Early diagnosis and management reduces the severity and possible complications of the disease process.

What are mucins produced by?

Mucinsare glycoproteins produced by submandibular and sublingual salivary glands and numerous minor salivary glands.

What is oxidative stress marker?

Oxidative stress marker . Oxidative stress is defined as the result of an imbalance between oxidant factors and protective antioxidant systems; it may occur due to an excess of free radicals, or by the diminishing of the antioxidant systems. Oxidative stress is enhanced during periodontitis.[55] .

Is saliva a biomarker?

Studies have shown that saliva is a biological product that can be easily collected and may be used for the quantification of 8-OHdG as an oxidative stress biomarker in the diagnos is and monitorization of the treatment in periodontitis.[57,58] Antioxidative capacity of saliva.

What are the antioxidants in saliva?

Antioxidants such as albumin, ascorbic acid, glutathione and traces of transferrin, lactoferrin, and caeruloplasmin are also found in saliva.[59] Emerging salivary diagnostic tools. The use of saliva for translational and clinical application has emerged at the forefront.

Is saliva a diagnostic test?

Numerous markers in saliva have been proposed and used as diagnostic tests for periodontal disease. Ideally, diagnostic tests should demonstrate high specificity and sensitivity. Given the complex nature of periodontal disease, it is unlikely that a single marker will prove to be both sensitive and specific.

Treatment FAQ