Treatment FAQ

what does pep treatment prevent

by Toy Nikolaus DVM Published 2 years ago Updated 2 years ago
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PEP (post-exposure prophylaxis) means taking medicine to prevent HIV after a possible exposure. PEP should be used only in emergency situations and must be started within 72 hours after a recent possible exposure to HIV.

Why was I prescribed Pep?

In addition, if you are a health care worker, you may be prescribed PEP after a possible exposure to HIV at work, such as from a needlestick injury. How Long Do You Need to Take PEP?

What is the Pep HIV treatment?

PEP is the use of antiretroviral medication to prevent HIV infection in an HIV-negative person who has had a specific high-risk exposure to HIV. Such an exposure typically occurs through sex or sharing syringes (or other injection equipment) with someone who has or might have HIV.

What is the typical course of treatment for Pep?

All persons offered PEP should be prescribed a 28-day course of a 3-drug antiretroviral regimen. Since adherence is critical for PEP efficacy, it is preferable to select regimens that minimize side effects, number of doses per day and the number of pills per dose.

When should Pep be used in emergency situations?

Update (May 23, 2018) PEP should be used only in emergency situations and must be started within 72 hours after a recent possible exposure to HIV. If you think you’ve recently been exposed to HIV during sex or through sharing needles and works to prepare drugs or if you’ve been sexually assaulted, talk to your health care provider...

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What is the benefit of using PEP?

PEP is the use of antiretroviral medication to prevent HIV infection in an HIV-negative person who has had a specific high-risk exposure to HIV. Such an exposure typically occurs through sex or sharing syringes (or other injection equipment) with someone who has or might have HIV.

What happens after taking PEP?

Does PEP have side effects? Some people experience no side-effects at all, but some people do. Side-effects are usually only mild to moderate, and include headaches, nausea, diarrhoea and vomiting. They are usually worse in the first week of taking PEP and reduce over time.

How long does PEP stay in your system?

Efavirenz can last in the system for days but the levels will drop over that time. You need to get tested at 4 weeks and 12 weeks after your exposure. The PEP will not effect your 12 week results. So, if they are negative, you do not have HIV.

What is the success rate of PEP?

Among studies assessing two-drug regimens, PEP completion rates were significantly higher for TDF-based regimens (78.4%) compared to ZDV-based regimens (58.8%).

What is PEP prescribed for?

PEP may be prescribed for people who are HIV negative or do not know their HIV status , and who in the last 72 hours:

What does PEP stand for?

PEP stands for post-exposure prophylaxis. The word “prophylaxis” means to prevent or control the spread of an infection or disease. PEP means taking HIV medicines within 72 hours (3 days) after a possible exposure to HIV to prevent HIV infection.

Can you use PEP for HIV?

PEP should be used only in emergency situations. It is not meant for regular use by people who may be exposed to HIV frequently. PEP is not a substitute for regular use of other HIV prevention methods.

When should you use PEP?

PEP should be used only in emergency situations. It is not meant for regular use by people who may be exposed to HIV frequently.

How Well Does PEP Work?

PEP is effective in preventing HIV infection when it’s taken correctly, but it’s not 100% effective. The sooner you start PEP after a possible HIV exposure, the better.

What Is PEP?

PEP, or post-exposure prophylaxis, is a short course of HIV medicines taken very soon after a possible exposure to HIV to prevent the virus from taking hold in your body.

How Long Do You Need to Take PEP?

If you are prescribed PEP, you will need to take the HIV medicines every day for 28 days.

What to do if you are taking PEP?

If you are taking PEP, talk to your health care provider if you have any side effect that bothers you or that does not go away. PEP medicines may also interact with other medicines that a person is taking (called a drug interaction).

Can you use PEP for HIV?

No. PEP should be used only in emergency situations. It is not intended to replace regular use of other HIV prevention methods. If you feel that you might exposed to HIV frequently, talk to your health care professional about PrEP (pre-exposure prophylaxis).

Who evaluates PEP?

Your health care provider or emergency room doctor will evaluate you, help you decide whether PEP is right for you, and work with you to determine which medicines to take for PEP.

Why do we take PEP?

PEP can be taken after a potential exposure in order to help prevent HIV transmission. The article below will focus on what exactly PEP is, when and how to take it, and what to expect.

When is PEP used?

PEP is taken in emergency situations when exposure to HIV may have occurred. When taken as directed, it’s effective at preventing HIV transmission. Some examples of situations where PEP may be used include after:

What is PEP for HIV?

HIV is a virus that affects the immune system. There are several ways to prevent contracting HIV. One prevention method is called postexposure prophylaxis (PEP), which is a combination of antiretroviral medications. PEP can be taken after a potential exposure in order ...

What is PEP in medicine?

PEP is actually a combination of different antiretroviral drugs. These drugs work to prevent the virus from replicating effectively in the body. The currently recommended combinations for most healthy adults and adolescents include:

How many people got HIV after PEP?

In 15 studies, which included exposures through sex, sexual assault, and injection drug use, only 19 out of 2,209 people got HIV after PEP. Just 1 case was attributed to PEP not working while the other 18 were associated with other behaviors or not taking PEP as directed.

How much does a PEP cost without insurance?

A complete course of PEP can cost from $597 to $1,000 without insurance. However, most insurance providers will cover PEP.

How many people were included in the 2017 PEP study?

A 2017 study retrospectively analyzed all courses of PEP at a single facility between 2010 and 2014. A total of 1,744 individuals that had available follow-up information were included.

How much less likely are HIV positive people to get PEP?

Overall, the ones that received the PEP were 89% less likely to seroconvert (become HIV-positive) than the ones that were given HIV alone. Obviously, it would be an ethical minefield to conduct this kind of study in humans.

Can you take PEP if you have HIV?

If your partner has an undetectable viral load, and has been on treatment for at least six months, you will not have been infected with the virus. "In this case there is a zero risk of transmission," says Brady. "People living with HIV and on effective treatment can't pass it on and therefore there is no need to take PEP.".

Is PrEP effective for HIV?

Taken daily, this medicine is highly effective at preventing HIV. "It's available in some form in all UK countries and when taken as prescribed is almost 100% effective at preventing HIV transmission. All of the information you need about PrEP is on the Terrence Higgins Trust website ," says Brady.

Is PEP a substitute for HIV?

Of course, PEP is not meant as a substitute for other forms of HIV prevention. For most people, it's best to stick with the usual advice about condoms - not least because they protect against other STIs and (where applicable) pregnancy.

Who can use PEP?

PEP is for people who may have been exposed to HIV in the last 3 days. PEP might be right for you if:

What is a PEP?

PEP is for people who may have been exposed to HIV in the last 3 days. PEP might be right for you if: You shared needles or works (like cotton, cookers, or water) with someone who may have HIV. If you were exposed to HIV in the last 3 days and want PEP, see a nurse or doctor or go to the emergency room immediately.

How do I get PEP?

You can get PEP from emergency rooms. It might also be available at some health clinics or Planned Parenthood health centers, and some doctors’ offices, but call first to make sure they have PEP in stock.

What happens when I’m on PEP?

If your nurse or doctor gives you PEP, you’ll need to take medicine 1-2 times a day for at least 28 days (4 weeks ). It’s important that you take every pill as directed and don’t skip doses, otherwise PEP may not work as well.

What are the side effects of PEP?

There can be side effects of PEP, like stomach aches and being tired. But PEP side effects aren’t dangerous, and they can be treated. Talk with your nurse or doctor if you have side effects that are really bothering you.

How to start PEP after being exposed to HIV?

If you were exposed to HIV in the last 3 days and want PEP, see a nurse or doctor or go to the emergency room immediately . Timing is really important. You must start PEP as soon as you can after being exposed to HIV for it to work. PEP is for emergencies. It can’t take the place of proven, ongoing ways to prevent HIV — like using condoms, ...

What happens if PEP doesn't work?

If PEP doesn’t work, you may have symptoms of the first stage of an HIV infection, like a fever or rash. If you have these symptoms while you’re on PEP, or within a month after finishing PEP, call your nurse or doctor.

Who should use PEP?

PEP should be used by anyone who thinks they have been exposed to HIV. People may be exposed to HIV in many ways:

What is PEP for HIV?

Post-exposure Prophylaxis (PEP) for HIV is an approach to prevent getting HIV after a possible exposure. Prophylaxis means disease prevention. PEP for HIV involves starting medications as soon as possible after an HIV exposure.

What is a PrEP?

PrEP is an effective prevention option that reduces the risk of getting HIV.

What are the side effects of PEP?

The most common side effects from PEP medications are nausea, headaches, fatigue, vomiting and diarrhea. These can be treated and are not life-threatening.

Is PEP 100% effective?

No, unfortunately PEP is not 100% effective. It does not guarantee that someone exposed to HIV will not get the virus.

Who should use PEP?

PEP should be used by anyone who has had a very recent single exposure to the HIV virus. The most common high-risk situations are within the occupational context, such as an inadvertent needlestick at the hospital, or the nonoccupational context, such as sexual exposure or injection drug use.

How Do You Take PEP?

PEP consists of three drugs that you take one–two times per day for 28 days. Ideally, the first dose of PEP should be administered immediately , within two hours but no later than 72 hours after an exposure, because the effectiveness of PEP decreases over time.

What is PEP in HIV?

What Is PEP? PEP is a way to help prevent the transmission of HIV in an HIV-negative person who may have been recently exposed to the virus. PEP consists of taking three HIV antiviral drugs for 28 days after exposure to the virus.

What happens if you take PEP and have a fever?

Talk to a healthcare provider if you develop a fever or rash during or after PEP use, as this may be a sign that the medication has not worked and you are experiencing the first symptoms of acute HIV infection.

How long does it take to get a follow up test for PEP?

Follow-up Tests. If you are on PEP, a healthcare professional will ask you to schedule a follow-up appointment within 72 hours. Your appointment will include: HIV testing. Lab monitoring for drug toxicity. Counseling. Repeat HIV testing will be obtained 30 days and 90 days after exposure.

Can you prescribe PEP with HIV?

Those who are unclear if a sexual partner has or had been exposed to HIV. Anyone who engages in needle sharing. Of note, if you are pregnant and have been exposed to HIV, your doctor will prescribe PEP with raltegravir instead of dolutegravir to limit the risk of birth defects.

Can PEP be used for HIV?

PEP should not be used as a regular means of preventing the transmission of HIV, and it does not prevent the spread of other sexually transmitted infections (STIs). Condoms, when used properly, are the most effective way of preventing HIV and most other STIs.

How effective is PEP?

PEP is effective in preventing HIV infection when it’s taken correctly, but it’s not 100% effective. PEP can lower the risk of getting HIV infection by more than 80%.

When should PEP be used?

PEP should be used only in emergencies after exposure to HIV. It should not be used as a replacement for or HIV prevention methods. PEP normally consists of three anti-HIV drugs from the different drug classes.

What is the role of PEP in the prevention of HIV?

Then, it spreads throughout the body causing HIV infection. PEP works by interfering with this pathway that HIV uses to cause infection in the body. The anti-HIV drugs get into the bloodstream and tissues. This prevents HIV from replicating within the body’s immune cells.

When is PEP necessary?

PEP must be taken by a person soon after a known or doubted exposure to HIV to prevent HIV transmission.

What is PEP in HIV?

Post-exposure prophylaxis (PEP) involves taking anti- HIV medications immediately after any potential exposure to HIV ( human immunodeficiency virus) to prevent HIV infection (acquired immune deficiency syndrome or AIDS ). PEP may prevent HIV from entering the cells in the body and stop someone from getting an HIV infection.

How does PEP work?

PEP works by interfering with this pathway that HIV uses to cause infection in the body. The anti-HIV drugs get into the bloodstream and tissues. This prevents HIV from replicating within the body’s immune cells. The medicines used in PEP are called antiretroviral medications (ART).

What are the drugs used in PEP?

The medicines used in PEP are called antiretroviral medications (ART). These include tenofovir, emtricitabine (these two drugs come in one pill), and a third drug either raltegravir or dolutegravir. These medications prevent HIV from making copies of itself and spreading through the body.

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