Treatment FAQ

what are the drugs used in triple therapy for treatment of duodenal ulcers

by Ms. Dahlia Koss Published 3 years ago Updated 2 years ago
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Triple therapy with sucralfate

Sucralfate

This medication is used to treat and prevent ulcers in the intestines.

, tetracycline

Tetracycline

Tetracycline is used to treat a wide variety of infections, including acne.

, and metronidazole
for Helicobacter pylori

Helicobacter pylori

Helicobacter pylori, previously known as Campylobacter pylori, is a Gram-negative, microaerophilic bacterium usually found in the stomach. It was identified in 1982 by Australian scientists Barry Marshall and Robin Warren, who found that it was present in a person with chronic gastritis and gastric ulcers, conditions not previously believed to have a microbial cause. It is also linked to the developme…

-associated duodenal ulcers Therapy of sucralfate, tetracycline, and metronidazole for 1 wk has a satisfactory but lower success rate in eradication of H. pylori when compared with the conventional triple therapy plus omeprazole

Omeprazole

Omeprazole is used to treat certain stomach and esophagus problems.

.

Triple therapy with omeprazole, amoxicillin and clarithromycin is effective against Helicobacter pylori infection
Helicobacter pylori infection
H. pylori infection represents a key factor in the etiology of various gastrointestinal diseases, ranging from chronic active gastritis without clinical symptoms to peptic ulceration, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue lymphoma.
https://www.ncbi.nlm.nih.gov › pmc › articles › PMC1539101
in gastric ulcer patients as well as in duodenal ulcer patients.

Full Answer

What is in the triple therapy of prevpac?

Uses for Triple Therapy. Prevpac® is a product containing three components: lansoprazole, amoxicillin, and clarithromycin. This medicine is used to treat patients with H. pylori infection and duodenal ulcers caused by H. pylori bacteria.

What is the best treatment for duodenal ulcer?

Patients with endoscopy-proven duodenal ulcer and who were H. pylori-positive were treated with clarithromycin 500 mg, omeprazole 20 mg, and amoxicillin 1000 mg, all given twice daily for 7 days. Upper endoscopy was repeated at week 6 to check for ulcer healing and H. pylori status. Results: A total of 117 patients were recruited.

Which medications are used to treat Helicobacter pylori (HP) infection?

Triple therapy with omeprazole, amoxicillin and clarithromycin is effective against Helicobacter pylori infection in gastric ulcer patients as well as in duodenal ulcer patients. Results of a randomized controlled trial in Japan

Is sucralfate effective in the treatment of Helicobacter pylori-associated duodenal ulcer?

Sucralfate inhibits H. pylori hemagglutinin, protease, and lipase and thus might affect colonization of the bacterium in the stomach. Objective: We compared the efficacy and side effects of triple therapy with sucralfate versus triple therapy with bismuth plus omeprazole in the treatment of H. pylori-associated duodenal ulcer (DU).

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What drugs are used in triple therapy?

Uses for Triple Therapy Prevpac® is a product containing three components: lansoprazole, amoxicillin, and clarithromycin. This medicine is used to treat patients with H. pylori infection and duodenal ulcers caused by H. pylori bacteria.

Which of the following drug is used for the treatment of duodenal ulcer?

Proton pump inhibitors — also called PPIs — reduce stomach acid by blocking the action of the parts of cells that produce acid. These drugs include the prescription and over-the-counter medications omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), esomeprazole (Nexium) and pantoprazole (Protonix).

Which of the following antibiotic is used as triple therapy in the management of peptic ulcers?

Conclusions: Triple therapy with omeprazole, amoxicillin and clarithromycin is a safe and effective regimen for the cure of H. pylori infection in GU patients as well as in DU patients. We recommend this triple regimen as a first-line treatment in all patients with peptic ulcers associated with H.

What is the best treatment for duodenal ulcer?

A duodenal ulcer is usually caused by an infection with a germ (bacterium) called Helicobacter pylori (H. pylori). A 4- to 8-week course of acid-suppressing medication will allow the ulcer to heal. In addition, a one-week course of two antibiotics plus an acid-suppressing medicine will usually clear the H.

What are the names of ulcer drugs?

Popular Gastric Ulcer Drugsomeprazole. $12.73.Pepcid. famotidine. $9.00.Prevacid. lansoprazole. $16.44.Nexium. esomeprazole. $149.01.Cytotec. misoprostol. $6.45.cimetidine. $36.88.Zegerid. omeprazole / sodium bicarbonate. $48.31.Axid. nizatidine. $51.93.More items...

Which of the following drugs are ulcer protective?

Antiulcer AgentsDexlansoprazole.Esomeprazole.Lansoprazole.Omeprazole.Pantoprazole.Rabeprazole.

What is triple therapy?

Abstract. Background: Triple therapy (proton pump inhibitor, clarithromycin and amoxicillin or an imidazole) is the first-line treatment for Helicobacter pylori infection. However, the effectiveness of triple therapy is decreasing due to the increase in antibiotic resistance.

Which combination of drugs is recommended for peptic ulcers?

Combination drug therapy regimens commonly used to treat an H. pylori infection include the following options: A proton pump inhibitor (PPI) plus clarithromycin plus amoxicillin or metronidazole. A proton pump inhibitor plus a bismuth compound plus metronidazole plus tetracycline.

What is the best triple therapy for H. pylori?

The standard course of triple therapy consists of clarithromycin with either metronidazole or amoxicillin plus a proton pump inhibitor (PPI), and is one of the most commonly used treatments for H pylori (6); however, questions remain regarding the optimal duration of therapy.

Which drug can cure ulcer permanently?

These ulcers can be completely healed. The development of H2 blockers (Pepcid®, Tagamet®, Axid®) and then Proton Pump Inhibitors (Prilosec®, Prevacid®, Nexium®, Aciphex®, Dexilant®, Zegerid®, and Protonix®) allow for most ulcers to be completely healed with medication.

Is Tramadol good for ulcer patient?

* Pain management guidelines propose tramadol as a treatment option for mild-to-moderate pain in patients at high risk of gastrointestinal side-effects, including peptic ulcer disease. * Tramadol may mask symptoms of peptic ulcer complications, yet tramadol's effect on peptic ulcer prognosis is unknown.

Is diclofenac good for ulcer patient?

Diclofenac and misoprostol combination is used to relieve the symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis) in patients who may develop stomach or duodenal ulcers from taking nonsteroidal anti-inflammatory drugs (NSAIDs).

Drugs used to treat Duodenal Ulcer

The following list of medications are in some way related to, or used in the treatment of this condition.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

What is the name of the medicine that is used to treat ulcers associated with a bacterial infection?

LANSOPRAZOLE; AMOXICILLIN; CLARITHROMYCIN is a combination of three medicines used to treat ulcers associated with a bacterial infection.

What is the name of the medication that is used to treat GERD?

Prevacid (lansoprazole) Lansoprazole (Prevacid) is a moderately priced drug used to treat GERD, heartburn, gastric ulcer, and duodenal ulcer. It works by reducing acid in the stomach. It is slightly more popular than comparable drugs. It is available in generic and brand versions.

What is Prilosec used for?

Prilosec (omeprazole) Omeprazole (Prilosec) is an inexpensive drug used to treat certain conditions where there is too much acid in the stomach, like ulcers and gastroesophageal reflux disease ( GERD ). It is more popular than comparable drugs.

What is Nexium used for?

Nexium ( esomeprazole) is used to treat gastroesophageal reflux disease ( GERD ), ulcers, certain bacteria in the stomach, and inflammation of the esophagus. It can also be used to prevent ulcers in patients taking medicines called NSAIDs.

What is rabeprazole used for?

It is used to treat gastroesophageal reflux disease ( GERD ), certain ulcers, inflammation of the esophagus, and Zollinger-Ellison Syndrome.

What is the class of drug that blocks the release of stomach acid?

Drug class: Histamine-2 Antagonists. NIZATIDINE is a type of antihistamine that blocks the release of stomach acid. It is used to treat stomach or intestinal ulcers. It can relieve ulcer pain and discomfort, and the heartburn from acid reflux.

Is omeprazole covered by Medicare?

This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. It is not covered by most Medicare and insurance plans, but some manufacturer and pharmacy coupons can help offset the cost.

What is triple therapy for PUD?

Triple therapy for PUD. PUD is the abbreviation for the condition more widely known as peptic ulcer disease. The condition is characterized by the formation of ulcers in the mucous membrane of the stomach and duodenum (which is the first portion of the small intestine).

What are the medications used for PUD?

Many different drugs are used in the treatment of PUD including antacids, H2 blockers, proton pump inhibitors, and antibiotics.

How to treat a PUD?

Treatment for PUD includes several approaches. It is essential to protect the surface of the stomach or duodenum and allow the ulcer or ulcers to heal. Furthermore, prevention is one more goal of the treatment. In people who are suffering from Helicobacter pylori infections, doctors recommend a so called triple therapy which eradicates the bacteria and allows proper healing of peptic ulcers. And finally, intake of drugs that have led to ulcer formation such as NSAIDs or steroids should be limited, if not completely restricted. Many different drugs are used in the treatment of PUD including antacids, H2 blockers, proton pump inhibitors, and antibiotics.

What causes peptic ulcers?

Causes of and Contributors to Peptic Ulcer Diseases (PUD) Damage to the surface of the stomach and duodenum is caused by inadequate protection (insufficient production of protective mucus) and an excess of stomach acid. Major contributing factors for PUD are an infection with Helicobacter pylori and the prolonged intake of NSAIDs ...

How long does a bismuth treatment last?

This is a highly efficient treatment which lasts 10 to 14 days. There are two treatment regimes, PPI-based triple therapy and Bismuth-based triple therapy. The first option includes a proton pump inhibitor (PPI) and two antibiotics. After the treatment is over, the patient may continue taking PPI for additional 2 weeks. Bismuth-based triple therapy includes Bismuth and also two kinds of antibiotics. The treatment may additionally include H2 receptor agonist. There are several antibiotics used in the mentioned therapies and some of them are clarithromycin, amoxicillin, metronidazole and tetracycline.

What antibiotics are used for a PUD?

There are several antibiotics used in the mentioned therapies and some of them are clarithromycin, amoxicillin, metronidazole and tetracycline. Surgery is performed only in case of complications such as perforation, obstruction, bleeding or if PUD, and can as such be considered a last-resort treatment.

Does peptic ulcer pain radiate backwards?

Patients suffering from peptic ulcer disease typically complain about burning epigastric pain (meaning pain in the central region of the abdomen), which may or may not radiate toward the back. In people with stomach ulcers, the pain intensifies with meals while, on the other hand, people suffering from duodenal ulcers feel pain relief after they eat.

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