Treatment FAQ

what are the 5 classes of hiv treatment

by Lea Berge Published 3 years ago Updated 2 years ago
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There are 5 main classes of HIV drugs:

  • Nucleoside Reverse Transcriptase Inhibitors (NRTIs or "nukes")
  • Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs or "non-nukes")
  • Integrase Inhibitors
  • Protease Inhibitors (PIs)
  • Entry Inhibitors

What are the HIV drug classes?
  • Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
  • Nucleoside reverse transcriptase inhibitors (NRTIs)
  • Protease inhibitors (PIs)
  • Fusion inhibitors.
  • CCR5 antagonists.
  • Integrase strand transfer inhibitors (INSTIs)
  • Post-attachment inhibitors.
Aug 16, 2021

Full Answer

What are the different classes of HIV drugs?

There are 5 main classes of HIV drugs: 1 Nucleoside Reverse Transcriptase Inhibitors (NRTIs or "nukes") 2 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs or "non-nukes") 3 Integrase Inhibitors 4 Protease Inhibitors (PIs) 5 Entry Inhibitors More ...

What are the treatment options for HIV?

The treatment for HIV is called antiretroviral therapy (ART). ART involves taking a combination of HIV medicines (called an HIV treatment regimen) every day. ART is recommended for everyone who has HIV. ART can’t cure HIV, but HIV medicines help people with HIV live longer, healthier lives. ART also reduces the risk of HIV transmission.

What are the different types of HIV entry inhibitors?

Post-attachment inhibitors are another type of entry inhibitor. These drugs block two kinds of receptor on the surface of white blood cells: the CCR5 and CXCR4 coreceptors. As with CCR5 antagonists, these drugs prevent HIV from entering the cells, thereby preventing the virus from replicating.

How many HIV drugs are available?

The U.S. Food and Drug Administration (FDA) has approved more than 30 HIV medicines to treat HIV infection. Browse the seven HIV drug classes and links here. What to Start: Choosing an HIV Treatment Regimen | NIH Skip to main content COVID-19 Get the latest public health information from CDC Get the latest research information from NIH | Español

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What are the 6 classes of antiretroviral drugs?

Classes of antiretroviral agents include the following:Nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs)Protease inhibitors (PIs)Nonnucleoside reverse transcriptase inhibitors (NNRTIs)Fusion inhibitors.CCR5 co-receptor antagonists (entry inhibitors)HIV integrase strand transfer inhibitors.

How many classes of antiretrovirals are there?

There are six main types ('classes') of antiretroviral drugs. Each class of drug attacks HIV in a different way. Generally, drugs from two (or sometimes three) classes are combined to ensure a powerful attack on HIV.

What is the best ARV combination?

A triple-drug combination of zidovudine, didanosine and nevirapine has been found to outperform combination therapy with two nucleosides as demonstrated by changes in the viral load and the CD4+ count.

What are the different treatment options for HIV?

There are two types of HIV treatment: pills and shots.Pills are recommended for people who are just starting HIV treatment. ... People who have had an undetectable viral load (or have been virally suppressed) for at least three months may consider shots.

What are the four types of Arvs?

Nucleoside reverse transcriptase inhibitors (NRTIs) emtricitabine (Emtriva) lamivudine (Epivir) stavudine (Stavudine)

What are the three types of Arvs?

Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI)-based: Abacavir + lamivudine, or ABC/3TC (Epzicom) Abacavir + lamivudine + zidovudine, or ABC/3TC/ZDV (Trizivir)

What is the name of the new ARV pill?

Early results from people taking a new antiretroviral medication called lenacapavir are promising. The long-acting drug is still at the research stage, but if the developers are able to pair it effectively with other drugs that also only needs to be taken twice a year, it could revolutionise HIV treatment.

What happens if you take ARVs while negative?

“When a HIV-positive person is given ARVs, it boosts their immunity, but when a HIV-negative person takes them, it just undermines their immunity and interferes with their body organs.” He, however, notes that some of the drugs administered to patients target viruses specifically, and not the body system.

What are the first line ARVs?

The preferred first-line ART regimen is tenofovir disoproxil fumarate-lamivudine-dolutegravir (TLD) for those clients ini a ng ART, experiencing side-effects to EFV, or for those who prefer to use DTG after being given all the necessary informa on.

What treatment would be given for low CD4 count?

A low CD4 count can be improved by treating the underlying problem. Anyone with HIV, including those with a low CD4 count, is treated with antiretroviral therapy, or ART. Antiretroviral therapy involves a combination of different medicines, called antiretrovirals, or ARVs.

What is HIV treatment?

HIV treatment (antiretroviral therapy or ART) involves taking medicine as prescribed by a health care provider. HIV treatment reduces the amount of...

When should I start HIV treatment?

Start HIV treatment as soon as possible after diagnosis. All people with HIV should take HIV treatment, no matter how long they’ve had HIV or how h...

What if I delay HIV treatment?

If you delay treatment, HIV will continue to harm your immune system. Delaying treatment will put you at higher risk for transmitting HIV to your p...

Are there different types of HIV treatment?

There are two types of HIV treatment: pills and shots. Pills are recommended for people who are just starting HIV treatment. There are many FDA-app...

What are HIV treatment shots?

HIV treatment shots are long-acting injections used to treat people with HIV. The shots are given by your health care provider and require routine...

Can I switch my HIV treatment from pills to shots?

Talk to your health care provider about changing your HIV treatment plan. Shots may be right for you if you are an adult with HIV who has an undete...

What are the benefits of taking my HIV treatment as prescribed?

HIV treatment reduces the amount of HIV in the blood (viral load). Taking your HIV medicine as prescribed will help keep your viral load low. HIV t...

Does HIV treatment cause side effects?

HIV treatment can cause side effects in some people. However, not everyone experiences side effects. The most common side effects are Nausea and vo...

What should I do if I’m thinking about having a baby?

Let your health care provider know if you or your partner is pregnant or thinking about getting pregnant. They will determine the right type of HIV...

Can I take birth control while on HIV treatment?

You can use any method of birth control to prevent pregnancy. However, some HIV treatment may make hormone-based birth control less effective. Talk...

How many classes of HIV are there?

There are many HIV medicines available for HIV regimens. The HIV medicines are grouped into seven drug classes according to how they fight HIV. The choice of an HIV regimen depends on a person's individual needs.

What is the treatment for HIV called?

The treatment for HIV is called antiretroviral therapy (ART). ART involves taking a combination of HIV medicines (called an HIV treatment regimen) every day. ART is recommended for everyone who has HIV. People with HIV should start taking HIV medicines as soon as possible.

How does HIV treatment affect the body?

By reducing the amount of HIV in the body, HIV medicines also reduce the risk of HIV transmission. A main goal of HIV treatment is to reduce a person’s viral load to an undetectable level. An undetectable viral load means that the level of HIV in the blood is too low to be detected by a viral load test.

Why is it important to have less HIV?

Having less HIV in the body gives the immune system a chance to recover and produce more CD4 cells.

How long after HIV infection can you start taking a drug?

(Early HIV infection is the period up to 6 months after infection with HIV.)

Can HIV be treated with ART?

People with HIV should start taking HIV medicines as soon as possible. ART can’t cure HIV, but HIV medicines help people with HIV live longer, healthier lives. ART also reduces the risk of HIV transmission. A main goal of HIV treatment is to reduce a person’s viral load to an undetectable level.

Can HIV medications interact with other HIV medications?

HIV medicines can interact with other HIV medicines in an HIV regimen or with other medicines a person is taking . Health care providers carefully consider potential drug interactions before recommending an HIV regimen.

What is the treatment for HIV?

HIV treatment involves taking medicines that slow the progression of the virus in your body. HIV is a type of virus called a retrovirus, and the combination of drugs used to treat it is called antiretroviral therapy (ART). ART is recommended for all people living with HIV, regardless of how long they’ve had the virus or how healthy they are.

How successful is HIV treatment?

HIV treatment is most likely to be successful when you know what to expect and are committed to taking your medicines exactly as prescribed. Working with your health care provider to develop a treatment plan will help you learn more about HIV and manage it effectively.

Why do people stay on HIV medication?

Getting and staying on HIV treatment because it reduces the amount of HIV in your blood (also called the viral load) to a very low level. This keeps you healthy and prevents illness. There is also a major prevention benefit. People living with HIV who take HIV medication daily as prescribed and get and keep an undetectable viral load have effectively no risk of sexually transmitting HIV to their HIV-negative partners. This is called treatment as prevention.

What is drug resistance in HIV?

What Is HIV Drug Resistance? Drug resistance can be a cause of treatment failure for people living with HIV. As HIV multiplies in the body, it sometimes mutates (changes form) and produces variations of itself. Variations of HIV that develop while a person is taking ART can lead to drug-resistant strains of HIV.

How long do HIV side effects last?

Some side effects can occur once you start a medicine and may only last a few days or weeks.

How soon can you start ART for HIV?

Treatment guidelines from the U.S. Department of Health and Human Services recommend that a person living with HIV begin ART as soon as possible after diagnosis. Starting ART slows the progression of HIV and can keep you healthy for many years.

Can HIV drugs prevent HIV?

With drug resistance, HIV medicines that previously controlled a person’s HIV are not effective against new, drug-resistant HIV. In other words, the HIV medicines can't prevent the drug-resistant HIV from multiplying. Drug resistance can cause HIV treatment to fail. A person can initially be infected with drug-resistant HIV or develop ...

How many classes of drugs are there for HIV?

HIV medicines are grouped into seven drug classesaccording to how they fight HIV.

How many HIV medications are there?

The U.S.Food and Drug Administration (FDA)has approved more than 30 HIV medicines to treat HIV infection. Some HIV medicines are available in combination (in other words, two or more different HIV medicines combined in one pill).

What is the treatment for HIV called?

The use of HIV medicines to treat HIV infection is called antiretroviral therapy (ART). People on ART take a combination of HIV medicines (called an HIV treatment regimen) every day.

How many HIV drugs are approved by the FDA?

The U.S. Food and Drug Administration (FDA) has approved more than 30 HIV medicines to treat HIV infection. Browse the seven HIV drug classes and links here.

What is the treatment for HIV?

Treatment. HIV drugs are also called antiretroviral drugs or antiretrovirals (ARVs). A whole treatment regimen is called antiretroviral therapy, or ART. The ARVs work because they attack the HIV virus directly--they cripple the ability of the virus to make copies of itself.

How many classes of drugs are in an ART regimen?

Usually an ART regimen consists of 3 different medicines from at least 2 classes (types) of drugs. This is because it takes a powerful combination of medicines to suppress the HIV virus. There are 5 main classes of HIV drugs: Each group attacks HIV in its own way and helps your body fight the infection.

How many types of medication are there for HIV?

A person with a recent HIV diagnosis usually starts treatment with a combination medication. There are at least 22 types, and a healthcare provider should recommend a combination medication that best suits a person’s requirements after a careful discussion of the options.

What are the two drugs that are used to treat HIV?

There are currently two FDA-approved PrEP agents, both of which are combinations of two HIV drugs in single pills: 1 Truvada — emtricitabine and tenofovir disoproxil fumarate 2 Descovy — tenofovir alafenamide and emtricitabine

What is a non-nucleoside reverse transcriptase inhibitor?

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) prevent HIV from replicating by binding to and altering reverse transcriptase, which HIV use s to replicate. This reduces the viral load of HIV in the person’s body.

Why are HIV complications less common?

Due to modern advances in antiretroviral therapy, HIV-related complications, such as opportunistic infections, are less common. Increasing numbers of people never develop stage 3 HIV infection, also known as AIDS.

How does antiretroviral therapy work?

In a person with HIV, antiretroviral therapy reduces the amount of the virus in the body to very low levels. When levels are so low that doctors consider them undetectable, the virus can no longer damage the body or transmit to others. recommend consistent treatment with antiretroviral therapy for everyone with HIV, ...

What is the treatment for HIV?

Side effects. Summary. Treatment for HIV involves taking medication that reduces the amount of the virus in the body. This is called antiretroviral therapy. Two other options, PEP and PrEP, can prevent HIV. HIV is a type of virus called a retrovirus. In a person with HIV, antiretroviral therapy reduces the amount of the virus in ...

Why is it so difficult to take HIV medication?

any issues that may make it difficult to take HIV medications consistently, such as a busy schedule, a lack of health insurance, or alcohol or drug use. the cost of the medications. It is important to acknowledge the substantial inequities in healthcare across regions and populations.

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