Treatment FAQ

treatment of dic when to initiate transfusion

by Roberta Robel Published 2 years ago Updated 2 years ago
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Treatment of underlying conditions is recommended in three types of DIC, with the exception of massive bleeding. Blood transfusions are recommended in patients with the bleeding and massive bleeding types of DIC. Meanwhile, treatment with heparin is recommended in those with the non-symptomatic type of DIC.Feb 20, 2014

When do you transfuse platelets in DIC?

Platelet transfusion may be considered in patients with DIC and severe thrombocytopenia, in particular, in patients with bleeding or in patients at risk for bleeding (eg, in the early postoperative phase or if an invasive procedure is planned).

What is the management of DIC?

Treatment includes correction of the cause and replacement of platelets, coagulation factors (in fresh frozen plasma), and fibrinogen (in cryoprecipitate) to control severe bleeding. Heparin is used as therapy (or prophylaxis) in patients with slowly evolving DIC who have (or are at risk of) venous thromboembolism.

When do you give heparin in DIC?

Heparin should be provided to those patients who demonstrate extensive fibrin deposition without evidence of substantial hemorrhage; it is usually reserved for cases of chronic DIC. Heparin is appropriate to treat the thrombosis that occurs with DIC.

What are the priority treatment of DIC?

Plasma transfusions to reduce bleeding. Plasma transfusion replace blood clotting factors affected by DIC. Transfusions of red blood cells and/or platelets. Anti-coagulant medication (blood thinners) to prevent blood clotting.

Why do you give FFP for DIC?

In conjunction with other options based on prompt and rigorous treatment of the underlying cause of DIC, fresh frozen plasma plays an important role in therapeutic management when overt bleeding is present or anticipated in DIC patients with disturbed coagulation or when an invasive procedure is being planned.

Is TXA contraindicated in DIC?

TEVAR is a radical way of curing the symptoms of DIC (20) and also reduces the aortic-specific mortality in the chronic phase (21). However, it could not be performed in the present patient due to the high operative risk. Solo use of tranexamic acid is contraindicated for DIC associated with aortic dissection.

How much FFP is needed for DIC?

The recommended adult therapeutic dose of FFP is 12-15 ml/kg (1), and the dose of FFP should always be at least 10 ml/kg (2); however a recent report showed in clinical practice 40% of adults received a FFP dose <10 ml/kg (2).

What does the nursing management of a patient with DIC include?

The following are the common nursing care planning and goals for clients with DIC: maintenance of hemodynamic status, maintenance of intact skin and oral mucosa, maintenance of fluid balance, maintenance of tissue perfusion, prevention of complications.

What are the stages of DIC?

Disease Forms/Subtypes DIC progresses through three continuous, overlapping stages: Hypercoagulation: Not noted clinically. Compensated or subclinical stage: May see alterations in coagulation profiles or end-organ dysfunction. Fulminant or uncompensated stage: Fulminant coagulopathy and signs of hemorrhage.

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