Why is radioactive iodine therapy given more than once?
Historically, radioactive iodine therapy has been given to patients more than once, because for a long time, it was the only treatment available for thyroid cancer. We continue to offer more than one treatment in some patients, if the disease recurs or spreads to other parts of the body.
How is radioactive iodine used to diagnose thyroid disease?
Depending on the dose, radioactive iodine can kill a portion, or all, of your thyroid. Your doctor will order a radioactive iodine uptake and scan to determine your dose, the cause of your hyperthyroidism, and information about your thyroid tissue. In this test, you will ingest a very small dose of radioactive iodine.
Is there a special caution for women using radioactive iodine?
A Special Caution for Women. Pregnant women or women who want to become pregnant in the next 6 months should not use radioactive iodine, as the treatment can destroy the fetus's thyroid and impair its development. In fact, women should wait a year before conceiving if they have been treated with the therapy.
What does iodine do for the thyroid gland?
Iodine is essential for proper function of the thyroid gland, which uses it to make the thyroid hormones. The thyroid is equipped with an active system or “pump” for moving iodine into its cells, where it is concentrated as iodide.
What endocrine glands would be most affected by radioactive iodine?
Potassium iodide protects only the thyroid, but it is the organ at greatest risk from radioactive iodine.
What is radioactive iodine therapy for thyroid cancer?
Radioactive iodine (RAI) treatment involves swallowing a capsule or liquid form of radioactive iodine that thyroid cells take up (absorb), destroying them. It's effective because healthy cells in the body don't usually absorb the radioactive iodine.
What happens with radioactive iodine treatment?
Radioactive iodine enters your bloodstream and is taken up by any thyroid- like cells. The radioactivity destroys the cancer cells. The radioactive iodine gives off radiation nearby and destroys the cancer cells over time.
What type of treatment is radioactive iodine?
Radioactive iodine is an effective type of treatment for cancer of the thyroid gland. This is because the radioactive iodine from the drink or capsule is absorbed into your body and picked up by the thyroid cancer cells, even if they have spread to other parts of the body. The radiation then destroys the cancer cells.
Where is the thyroid gland located and what does it do?
The thyroid gland is an endocrine gland in your neck. It makes two hormones that are secreted into the blood: thyroxine (T4) and triiodothyronine (T3). These hormones are necessary for all the cells in your body to work normally.
What is radiation therapy for cancer?
Radiation therapy (also called radiotherapy) is a cancer treatment that uses high doses of radiation to kill cancer cells and shrink tumors. At low doses, radiation is used in x-rays to see inside your body, as with x-rays of your teeth or broken bones.
When is radioactive iodine given?
Currently, radioactive iodine therapy is only used to treat hyperthyroidism (overactive thyroid gland) and certain types of thyroid cancer. It's also used to help determine the root causes of hyperthyroidism and to see if certain thyroid cancers have spread to other parts of the body.
What is iodine used for in the body?
Iodine is a mineral found in some foods. The body needs iodine to make thyroid hormones. These hormones control the body's metabolism and many other important functions. The body also needs thyroid hormones for proper bone and brain development during pregnancy and infancy.
When is radioactive iodine necessary?
You might have radioactive iodine treatment: after surgery, to kill any cancer cells that may have been left behind. to treat thyroid cancer that has spread. to treat thyroid cancer that has come back after it was first treated.
What causes thyroid problems?
Problems with the thyroid can be caused by: iodine deficiency. autoimmune diseases, in which the immune system attacks the thyroid, leading either to hyperthyroidism (caused by Graves' disease) or hypothyroidism (caused by Hashimoto's disease) inflammation (which may or may not cause pain), caused by a virus or ...
Where does radioactive iodine come from?
Most radioactive forms of iodine are produced as a byproduct of a fission. Fissioning that occurs without any outside cause is called "spontaneous fission." reaction from either nuclear weapons testing or nuclear power plants. Some forms of radioactive iodine are manufactured for use in medicine.
What are thyroids?
Your thyroid is a butterfly-shaped gland in your neck, just above your collarbone. It is one of your endocrine glands, which make hormones. Thyroid hormones control the rate of many activities in your body. These include how fast you burn calories and how fast your heart beats.
What is the radiation used for thyroid cancer?
The radiation dose used here is much stronger than the one used in radioiodine scans, which are described in Tests for Thyroid Cancer. This treatment can be used to ablate (destroy) any thyroid tissue not removed by surgery or to treat some types of thyroid cancer that have spread to lymph nodes and other parts of the body.
How long after radiation therapy can you go home?
Depending on the dose of radioiodine used and where you are being treated, you might need to be in the hospital for a few days after treatment, staying in a special isolation room to prevent others from being exposed to radiation. Some people may not need to be hospitalized. Once you are allowed to go home after treatment, you will be given instructions on how to protect others from radiation exposure and how long you need to take these precautions. These instructions may vary slightly by treatment center. Be sure you understand the instructions before you leave the hospital.
How long should I take thyrotropin before RAI?
Another way is to get an injection (shot) of thyrotropin (Thyrogen), which can make withholding thyroid hormone for a long period of time unnecessary. This drug is given daily for 2 days, followed by RAI on the 3 rd day. Most doctors also recommend that you follow a low iodine diet for 1 or 2 weeks before treatment.
How to treat RAI?
For RAI therapy to be most effective, you must have a high level of thyroid-stimulating hormone (TSH or thyrotropin) in the blood. This hormone is what makes thyroid tissue (and cancer cells) take up radioactive iodine. If your thyroid has been removed, there are a couple of ways to raise TSH levels before being treated with RAI: 1 One way is to stop taking thyroid hormone pills for several weeks. This causes very low thyroid hormone levels (hypothyroidism), which makes the pituitary gland to release more TSH. This intentional hypothyroidism is temporary, but it often causes symptoms like tiredness, depression, weight gain, constipation, muscle aches, and reduced concentration. 2 Another way is to get an injection (shot) of thyrotropin (Thyrogen), which can make withholding thyroid hormone for a long period of time unnecessary. This drug is given daily for 2 days, followed by RAI on the 3 rd day.
Can you use rai for thyroid cancer?
Discuss your risks and benefits of RAI therapy with your doctor. Radioactive iodine therapy cannot be used to treat anaplastic (undifferentiated) and medullary thyroid carcinomas because these types of cancer do not take up iodine.
Can radiation cause irregular periods?
Radioactive iodine may also affect a woman’ s ovaries, and some women may have irregular periods for up to a year after treatment.
Does radioactive iodine help with thyroid cancer?
Radioactive iodine therapy helps people live longer if they have papillary or follicular thyroid cancer (differentiated thyroid cancer) that has spread to the neck or other body parts, and it is now standard practice in such cases. But the benefits of RAI therapy are less clear for people with small cancers of the thyroid gland ...
Why is iodine important for the thyroid gland?
Iodine is essential for proper function of the thyroid gland, which use s it to make the thyroid hormones. The thyroid is equipped with an active system or “pump” for moving iodine into its cells, where it is concentrated as iodide. The thyroid gland is the only tissue in the body that takes up and holds onto iodine.
What is iodine used for?
Iodine, in the form of iodide, is made into two radioactive forms of iodine that are commonly used in patients with thyroid diseases: I-123 ( harmless to thyroid cells) and I-131 ( destroys thyroid cells ). The radiation emitted by each of these forms of iodine can be detected from outside the patient to gain information about thyroid function ...
What is the I-123 isotope used for?
I-123 is the usual isotope used to take pictures and determine the activity of the intact thyroid gland ( Thyroid Scan and Radioactive Iodine Uptake, RAIU ), since it is harmless to thyroid cells. No special radiation precautions are necessary after a thyroid scan or RAIU using I-123. I-131 can also be used to take pictures of the thyroid gland, ...
What is the purpose of I-131?
THYROID CANCER – Large doses of I-131 are used to destroy thyroid cancer cells (see Thyroid Cancer brochure ). This is performed after the remaining thyroid cells ( including any cancer cells) are stimulated by raising TSH levels by either withdrawing the thyroid hormone pills or by treating with recombinant human TSH.
Is rai safe for X-rays?
RAI is safe to use in individuals who have had allergic reactions to seafood or X-ray contrast agents, since the reaction is to the compound containing io dine, not the iodine itself. RAI is given by mouth in pill or liquid form.
When can you stop breast feeding after I-131?
This protects the baby who would otherwise receive radioactive milk and the mother’s breasts which concentrate RAI. Breastfeeding must be stopped at least 6 weeks before administration of I-131 treatment and should not be restarted after administration of RAI, but can be safely done after future pregnancies.
Can RAI cause thyroid cancer?
Hypothyroidism is a common side effect of RAI for hyperthyroidism and always seen after RAI for thyroid cancer. This is usually easily treated with thyroid hormone replacement (see Hypothyroidism brochure ). Some studies suggest a slight increase in thyroid cancers may be seen after RAI treatment for hyperthyroidism.
What is radioactive iodine ablation?
Your doctor may refer to it as radioactive iodine ablation (ablation is a term that refers to destruction or erosion). This article will focus on what you might expect when you are faced with the total elimination of your thyroid gland and its key functions. Graves disease, the most common form of hyperthyroidism, occurs most often in women, ...
How long does iodine last?
Other side effects of radioactive iodine include: Metallic taste in the mouth: This can last for a few weeks. Nausea: This usually subsides one to two days after treatment. Swollen salivary glands: This can last for a few weeks.
What are the side effects of iodine?
Other side effects of radioactive iodine include: 1 Metallic taste in the mouth: This can last for a few weeks. 2 Nausea: This usually subsides one to two days after treatment. 3 Swollen salivary glands: This can last for a few weeks. It is caused by iodine absorbed by the salivary glands, though stimulating saliva flow a day after treatment (by sucking a lemon drop, for instance) is an effective remedy.
How long after iodine treatment can you drink water?
For the first 3 days after treatment, stay a safe distance away from others (6 feet is enough). Avoid public places and drink plenty of water (to encourage the removal of radioactive iodine through your urine). For the first three days, do not share items (utensils, bedding, towels, and personal items) with anyone else.
What cells absorb iodine?
Thyroid cells are the main cells in the body that can absorb iodine, so there is very little radiation exposure to the rest of your body's cells. When the thyroid cells absorb the radiation, they are damaged or destroyed. Approximately 90% of patients need only one dose before they are cured of their hyperthyroidism.
How long does it take for a thyroid to heal?
Though you may only need a single dose, it may take up to six months before the medication fully destroys all or part of the thyroid. Fortunately, most patients experience reduced symptoms about a month after treatment. If your symptoms persist 6 months after treatment, you may need a second dose.
Does iodine kill thyroid cells?
The radioactive iodine often kills an excessive amount of thyroid cells, leaving the thyroid unable to produce enough hormones—the opposite problem you had before. It might seem odd to replace one disorder with another, but hypothyroidism is much easier to treat on a long-term basis than hyperthyroidism.
Why is radioactive iodine used in thyroid cancer?
Radioactive iodine takes advantage of the fact that thyroid cells and thyroid cancer cells absorb iodine; therefore, it has been used to diagnose or treat various thyroid ...
How long before radioactive iodine is given?
Patients are placed on a low-iodine diet two weeks prior to receiving radioactive iodine. This makes them iodine-deficient and increases the chance that the thyroid cells will absorb the radioactive iodine dose.
What is the purpose of RAI after thyroid surgery?
The goal of RAI remnant ablation treatment is to kill any remaining thyroid cells. This is important for several reasons:
What is RAI used for?
RAI is then absorbed by the thyroid cells and can be used to diagnose or treat thyroid problems. I-131 is commonly used to treat thyroid disorders, such as hyperthyroidism, through RAI ablation (medically destroying the thyroid gland without surgery). In addition, large doses of I-131 are used to destroy thyroid cancer cells, ...
What is the protein that makes up thyroid cells?
Thyroid cells make a protein called thyroglobulin (Tg). If we can destroy all of the thyroid cancer cells, the Tg should be undetectable. While the majority of patients will receive RAI remnant ablation, we strive to give the lowest radiation dose possible.
What is the radioactive isotope of iodine?
A radioactive isotope (RAI) is a substance that gives off radiation. RAI is given by mouth, in pill or liquid form.
Is I-131 radiation safe for pregnant women?
The medical precautions are for the caregiver and family as well as the patient. Since I-131 produces radiation, patients must do their best to avoid radiation exposure to others, particularly to pregnant women and small children.
