
During surgery, right to the area where the cancer was, to kill any cancer cells that may be left behind. This is called intraoperative radiation therapy or IORT. Along with chemo to help control cancer if a person is not healthy enough for surgery. To ease symptoms if advanced colon cancer is causing intestinal blockage, bleeding, or pain.
How does radiotherapy work for colon cancer?
Radiation therapy uses high-energy rays or particles to destroy cancer cells. Radiation therapy is used more often in treating rectal cancer than colon cancer. Your healthcare team will consider your personal needs to plan the type and amount of radiation, and when and how it is given. You may also receive other treatments.
What types of radiation are used to treat colon and rectal cancers?
Different types of radiation therapy can be used to treat colon and rectal cancers. EBRT is the type of radiation therapy used most often for people with colon or rectal cancer. The radiation is focused on the cancer from a machine outside the body. It's a lot like getting an x-ray, but the radiation is more intense.
What are the treatment options for colon cancer?
To ease symptoms if advanced colon cancer is causing intestinal blockage, bleeding, or pain. To help treat colon cancer that has spread to other areas, such as the bones, lungs, or brain. For rectal cancer, radiation therapy is a more common treatment and may be used:
What is endocavitary radiation therapy for colon cancer?
Endocavitary radiation therapy: For this treatment, a small balloon-like device is placed into the rectum to deliver high-intensity radiation for a few minutes. This is typically done in 4 treatments (or less), with about 2 weeks between each treatment. This can let some patients, particularly elderly patients, avoid major surgery and a colostomy.

How is radiation therapy administered for colon cancer?
For this treatment, a radioactive source is put inside your rectum next to or into the tumor. This allows the radiation to reach the rectum without passing through the skin and other tissues of the belly (abdomen), so it's less likely to damage nearby tissues.
Where is the best place to treat colon cancer?
Mayo Clinic doctors are highly respected for their expertise in diagnosis and treatment of colon cancer. Mayo Clinic doctors care for more than 3,500 people with colon cancer each year. Nationally recognized expertise.
What do you do during radiation treatment?
During radiation therapy: Be gentle and protect your skinWash the treated skin gently every day with warm water. ... Use a gentle, low-pH cleanser if you need to cleanse. ... Ignore the lines drawn on your skin. ... Avoid shaving the treated skin. ... Apply moisturizer every day as directed.
What is the success rate of radiation therapy for colon cancer?
RT is effective for advanced or metastatic rectal cancers when palliation of symptoms is required locally. A retrospective study of 99 patients demonstrated a response rate of 62.5% to 86.7% with median duration response from 4.2–5.4 months.
What is the difference between colorectal cancer and colon cancer?
Colorectal cancer is a term used to describe both colon and rectal cancer. Both cancers affect the large intestine. Cancer cells that develop in the colon are called colon cancer, while cancer cells that grow in the rectum are called rectal cancer.
What stage is colon cancer that has spread to lymph nodes?
Cancer that has spread past the lining of the colon and has affected the lymph nodes is considered stage III colon cancer. In this stage, even though the lymph nodes are affected, the cancer has not yet affected other organs in the body. This stage is further divided into three categories: IIIA, IIIB and IIIC.
What should you not do during radiation?
Avoid raw vegetables and fruits, and other hard, dry foods such as chips or pretzels. It's also best to avoid salty, spicy or acidic foods if you are experiencing these symptoms. Your care team can recommend nutrient-based oral care solutions if you are experiencing mucositis or mouth sores caused by cancer treatment.
Can you drive yourself to and from radiation treatments?
Unless you feel ill, you can typically drive yourself to treatment. In fact, many patients are able to work full-time during their treatment.
How do you feel during radiation treatment?
The most common early side effects are fatigue (feeling tired) and skin changes. Other early side effects usually are related to the area being treated, such as hair loss and mouth problems when radiation treatment is given to this area. Late side effects can take months or even years to develop.
Is radiation therapy painful?
Does radiation therapy hurt? No, radiation therapy does not hurt while it is being given. But the side effects that people may get from radiation therapy can cause pain and discomfort.
Why do doctors recommend radiation therapy?
Doctors may recommend radiation therapy or chemoradiation before surgery to help shrink tumors and prevent cancer from recurring after surgery. They may also prescribe chemoradiation after surgery to help rid the body of any remaining cancer cells. Radiation therapy may also be used when surgery is not recommended because ...
What are the side effects of radiation therapy?
Common side effects of radiation therapy for colorectal cancer include fatigue, diarrhea, frequent urination, gas, and cramping. Our doctors and cancer center support services can help manage these side effects using integrative medicine therapies at Perlmutter Cancer Center. Our nutritionists can provide dietary guidance after treatments for colorectal cancer.
How does radioembolization work for liver cancer?
When colorectal cancer has spread to the liver, an interventional radiologist may use radioembolization to deliver targeted radiation directly to cancer cells, sparing healthy cells. In this procedure, tiny beads filled with the radioactive isotope yttrium, or Y-90, are placed into blood vessels that feed a tumor through a catheter that’s inserted into the skin on the arm. The microspheres travel through the bloodstream to the tumor. After several weeks, the radiation decreases and then disappears.
What is intensity modulated radiation?
Intensity-modulated radiation therapy is more targeted than the three-dimensional conformal approach. It allows doctors to divide treatment into many small, computer-controlled beams of different strength s. Together, these beams closely conform to the size, shape, and location of the colorectal cancer.
Why do doctors use advanced imaging during radiation therapy?
Our doctors routinely use advanced imaging during image-guided radiation therapy to ensure that the radiation accurately targets colorectal cancer while avoiding important organs. This approach helps compensate for changes in the position of organs, such as the bladder or rectum, during treatment. By using image-guided radiation therapy, our doctors are able to target the tumor accurately while reducing the exposure of healthy tissue to radiation.
How does intensity modulated radiation therapy work?
Using intensity-modulated radiation therapy, doctors are able to adjust the radiation dose within millimeters to spare surrounding healthy tissue. This approach may enable doctors to use higher doses of radiation therapy when needed, while still being able to spare nearby healthy tissue and organs.
What is the name of the machine that focuses radiation around the body?
Our doctors use several different types of external beam radiation therapy, which are typically delivered by a machine called a linear accelerator. This machine focuses high energy X-rays from multiple angles around the body to deliver radiation that matches the shape of the tumor.
Why is radiation less effective in colon cancer?
And so the radiation often plays less of a role in that area because the spaces are a little bit easier for our surgeons to remove the cancer.
What is radiation therapy?
Radiation therapy is a treatment that uses X-rays to kill cancer cells. Join radiation oncologist Sudha Amarnath, MD as she discusses how this therapy can be used to treat colon and rectal cancer, the different types of radiation therapy, and what a patient can expect during these sessions.
What are the tools that we think about when we think about the care of a patient who has a new cancer
So radiation therapy is one of the three tools that we really think about when we're thinking about the care of a patient who has a new cancer diagnosis. And so the other two tools are ones that I think most patients are often more familiar with, which are surgery and chemotherapy.
How many cancer patients end up getting radiation?
And so radiation actually plays a really large role in the care of cancer patients, and almost 60 to 70% of patients who have a cancer diagnosis will end up getting radiation at some point during their course of therapy. But it is one of the three tools that we use in the care of many cancer patients.
Why is radiology called diagnostic radiology?
And it's called diagnostic radiology because we use those images primarily for diagnosis. On the radiation therapy side, we use radiation in a therapeutic setting. So we're essentially using radiation to kill cancer cells.
When was radiation used for cancer?
But radiation has actually been used for cancer treatment since really the late 1800s, early 1900s, so it's one of the oldest therapies that we know is effective against cancers. Radiation in the modern era works in combination with chemo and surgery to really treat patients for a number of different cancers.
Where are protons used?
So protons can be used in that setting to really target that tumor in the spine, but prevent radiation from really getting to the spinal cord. And so there are really specific instances where protons can be helpful. Like I mentioned in the spine, in the brain, kind of near the brainstem.
What is radiation therapy?
Radiation therapy uses high-energy beams of X-rays or other particles to kill cancer cells or stop them from growing.
When might radiation therapy be used?
Radiation therapy is a common part of the treatment for rectal cancers. It’s also may be used to treat colon cancer. But surgery is the main treatment for both colon and rectal cancer.
What happens during radiation therapy?
For colorectal cancer, radiation most commonly comes from a large machine that sends X-ray beams into the tumor. This is called external radiation. It's a lot like getting an X-ray, but more radiation is used.
Getting ready for radiation
Before your first treatment, you’ll have an appointment to plan for the treatment. This is called simulation. During the simulation:
On the days you get radiation
Radiation treatment is like getting an X-ray. The radiation is stronger so it can kill cancer cells. You can’t feel radiation, so the process will be painless. Also, you will not be radioactive afterward.
What to expect after radiation therapy
Radiation therapy affects normal cells as well as cancer cells. This can cause side effects. The side effects depend on the amount and type of radiation. Some people have few or no side effects. But if you have them, your doctor may change the dose of your radiation or how often you have treatments.
Possible long-term side effects
Radiation therapy can cause some long-term side effects that may not show up until many years after treatment. It depends on where the radiation was aimed and the dose used. These can be more serious, so you should watch for them and talk with your healthcare team about what to expect.
What happens when you get radiation for colorectal cancer?
Once these damaged cancer cells die, the immune system can then break down the cells. When radiation is used in the treatment of colorectal cancer, it is typically used in conjunction with other treatment methods. When used with surgery, radiation therapy is typically used to shrink tumors to make them easier to remove, ...
When is radiation used for cancer?
Radiation is used alongside chemotherapy when a patient isn’t healthy enough for surgery, to treat cancer that has spread to other areas of the body, or palliatively, to ease symptoms of advanced stage cancer.
What is radiation therapy used for?
Radiation therapy is only used to treat colon and rectal tumors under certain circumstances , and usually used in conjunction with other colorectal cancer treatments. Find out more about colorectal cancer chemotherapy and colorectal cancer surgery .
What is the best treatment for rectal cancer?
Radiation Therapy for Rectal Cancer. Radiation therapy is more often used to treat rectal cancer in comparison to colon cancer, and it is used in similar ways – to treat tumors that have grown next to or into other organs, to improve your quality of life, or to improve outcomes of surgery. Uses of radiation therapy to treat rectal cancer include:
How does radiation work?
Radiation works by killing cancer cells by damaging their DNA, rendering them unable to continue dividing in definitely.
How is radiation delivered?
External-beam radiation therapy is delivered by a machine aimed at the location of your tumor. Internal radiation therapy is delivered by a radiation source that is put inside the body in solid or liquid form.
What is intraoperative radiation therapy?
Intraoperative Radiation Therapy (IORT): Kill lingering cancer cells during surgery. Kill lingering cancer cells after surgery. Treat a person who is not healthy enough for surgery, along with chemo. Treat cancer that has metastasized to other areas of the body.
What is the treatment for colon cancer?
Colon cancer is typically treated with surgery and chemotherapy but radiation therapy (or radiotherapy) may be an important part of your treatment plan if you have advanced disease. Radiotherapy treatments may also be used as palliative care to ease cancer symptoms.
Does Roswell Park have radiation?
It matters where you receive your radiation treatments and not all radiotherapy centers are equal. Roswell Park’s Radiation Medicine department has a full-time staff of radiation oncologists, dosimetrists, physicists, radiation therapists and radiation nurses, that work with your colorectal team to ensure your radiotherapy is optimally coordinated and sequenced with your other treatments. Every patient’s radiotherapy is planned and delivered by a radiation oncology team with the knowledge and experience to use the latest technology, offer the highest level of quality and safety and focus on what’s best for you at all times.
External radiation therapy
During external radiation therapy (also called external beam radiation therapy), a machine directs radiation through the skin to the tumour and some of the tissue around it.
Brachytherapy
Brachytherapy is a type of internal radiation therapy. It uses a radioactive material called a radioactive isotope. It is placed right into the tumour or very close to it. Radioactive materials can also be placed in the area where the tumour was removed. The radiation kills the cancer cells over time.
Side effects
Side effects can happen with any type of treatment for colorectal cancer, but everyone’s experience is different. Some people have many side effects. Other people have only a few side effects.
Questions to ask about radiation therapy
Find out more about radiation therapy and side effects of radiation therapy. To make the decisions that are right for you, ask your healthcare team questions about radiation therapy.
What type of radiation is used for rectal cancer?
The types of radiation treatments most commonly used for rectal cancer include: External beam radiation: this type of radiation delivers a beam of high-energy x-rays to a patient’s tumor from outside the body. Radiation oncologists at Johns Hopkins may use intensity-modulated radiation therapy ...
How long does it take to get radiation for rectal cancer?
Radiation treatments for rectal cancer may be delivered in small doses over five to six weeks of daily treatment, or they may be delivered in higher doses over a condensed time period of five days.
What is brachytherapy for rectal cancer?
Brachytherapy: Used less often than external beam radiation to treat rectal cancer, this radiation treatment is a targeted, high-dose treatment that is delivered directly in or near the tumor. Johns Hopkins is one of the only hospitals in the country to explore endorectal high-dose rate brachytherapy for rectal cancer, ...
What is IMRT in cancer?
Radiation oncologists at Johns Hopkins may use intensity-modulated radiation therapy (IMRT), which delivers targeted doses of radiation in a pattern to match the shape of the tumor; or image-guided radiation therapy (IGRT), which uses images taken before and during the radiation delivery to guide the treatment.
What is the imaging of rectum cancer?
Before radiation, chemotherapy or surgery for rectal cancer, imaging specialists may use one or more techniques to determine where the tumors are located in the rectum and how far they have spread into surrounding tissue and lymph node.
Can radiation be used for cancer?
In particular, radiation is recommended for patients with cancer that has spread to lymph nodes, or has spread beyond the wall of the rectum, as well as locally recurrent rectal cancers. Amol Narang, M.D., an associate professor of radiation oncology at Johns Hopkins and a member of the Rectal Cancer Multidisciplinary Clinic, ...
Is the small intestine sensitive to radiation?
In other cases, the small intestine may be in the field of radiation for tumors that occur very high in the rectum, closer to the colon. Since the small intestine is very sensitive to radiation, an intense five-day course of treatment might not be the first choice for patients and their radiation oncology team.
