How are cancers caused by HPV treated?
Human papillomavirus (HPV) causes several types of cancer, including cervical, anal, and head and neck cancers. People with these tumors are more easily cured with radiation and chemotherapy than people with tumors not caused by HPV. Scientists at Memorial Sloan Kettering now think they understand why.
Can cancer caused by HPV be cured?
The Cure Rate Is Very High “If a patient's tumor is HPV-positive, the longterm cure rate for most stages is 80 to 90 percent,” reports Dr. Hu, professor in the Departments of Radiation Oncology and Otolaryngology—Head and Neck Surgery.
What happens if HPV is cancerous?
HPV can cause cervical and other cancers, including cancer of the vulva, vagina, penis, or anus. It can also cause cancer in the back of the throat (called oropharyngeal cancer). This can include the base of the tongue and tonsils. Cancer often takes years, even decades, to develop after a person gets HPV.
How do you treat high risk HPV?
Surgery is necessary to remove precancerous cells caused by high risk HPV. This is to prevent the cells from becoming cancerous. A doctor can remove these cells from the cervix with a procedure called loop electrosurgical excision or with cervical cryotherapy.
How long does it take for HPV to turn into cancer?
HPV-related cancers often take years to develop after getting an HPV infection. Cervical cancer usually develops over 10 or more years. There can be a long interval between being infected with HPV, the development of abnormal cells on the cervix and the development of cervical cancer.
What percentage of HPV turns into cancer?
Number of HPV-Attributable Cancer Cases per YearCancer siteAverage number of cancers per year in sites where HPV is often found (HPV-associated cancers)Percentage probably caused by any HPV typeaMale16,68072%TOTAL46,14379%Female25,71983%Male20,42474%9 more rows
What is the treatment for HPV 16 and 18?
Colposcopy is recommended if HPV genotyping is positive for types 16 or 18, and it can be considered if it is infeasible for the patient to return for cytology alone (1274). HPV 16 is the highest-risk HPV type.
Do I need a colposcopy if I have HPV?
If you test positive for HPV 16/18, you will need to have a colposcopy. If you test positive for HPV (but did not have genotyping performed or had genotyping and tested negative for 16/18), you will likely have a colposcopy.
What kind of cancers can HPV cause?
Almost all cervical cancer is caused by HPV. Some cancers of the vulva, vagina, penis, anus, and oropharynx (back of the throat, including the base of the tongue and tonsils) are also caused by HPV. Almost all cervical cancer is caused by HPV.
Will a hysterectomy cure HPV?
A hysterectomy will not cure the HPV which has caused the CIN, as there is no cure for HPV, but the CIN cannot have spread anywhere else in your body and will only be in your cervix area-it doesn't travel through the bloodstream, and remains where the HPV infection is.
What are treatment options for HPV?
There is no treatment for the virus itself. However, there are treatments for the health problems that HPV can cause: Genital warts can be treated by your healthcare provider or with prescription medication. If left untreated, genital warts may go away, stay the same, or grow in size or number.
What is the best medicine for HPV?
Medications for Human PapillomavirusImiquimod. This topical medication helps eliminate warts by boosting the immune system. ... Podofilox. Podofilox stops the growth of cells that cause genital warts. ... Sinecatechins. ... Trichloroacetic Acid.
What Is Human Papillpoma Virus (HPV)?
HPV stands for human papilloma virus. It is a very common virus. There are about 100 types of HPV that affect different parts of the body. About 30...
How Is HPV Related to Cervical Cancer?
Certain strains of HPV can cause changes in the cells of the cervix, a condition called cervical dysplasia. If it is not treated, dysplasia can adv...
How Do You Get Human Papilloma Virus (HPV)?
Genital HPV is spread through contact with (touching) the skin of someone who has an HPV infection. Contact includes vaginal, anal, and oral sex. S...
What Are The Symptoms of HPV?
In many cases, HPV causes no symptoms. When they do occur, the most common symptom is warts in the genital area. Signs of infection can appear week...
Overview
- The human papillomavirus (HPV) test detects the presence of the human papillomavirus, a virus that can lead to the development of genital warts, abnormal cervical cells or cervical cancer.Your doctor might recommend the HPV test if: 1. Your Pap test was abnormal, showing atypical squamous cells of undetermined significance (ASCUS) 2. You're age 30 or olderThe HPV test is …
Treatment
- Treatment is directed to the macroscopic (e.g., genital warts) or pathologic precancerous lesions caused by HPV. Subclinical genital HPV infection typically clears spontaneously; therefore, specific antiviral therapy is not recommended to eradicate HPV infection. Precancerous lesions are detected through cervical cancer screening (see Cervical Cancer, Screening Recommendatio…
- Over-the-counter ointments, lotions and plasters are available to treat common skin warts. Do not use them for warts on the face, genitals or anus. They should not be used by people with diabetes, poor circulation or infected warts. Over-the-counter remedies use strong chemicals to slowly destroy the wart over a period of weeks or months. For faster and more lasting treatment, your d…
- Theres no cure for HPV. But theres a lot you can do to keep HPV from having a negative impact on your health. There are vaccines that can help protect you from ever getting certain types of HPV. Genital warts can be removed by your nurse or doctor. High-risk HPV can usually be easily treated before it turns into cancer, which is why regular Pap/HPV tests are so important. While c…
- Several therapies exist for the treatment of genital warts, but none have proven to be extremely effective or to decrease transmission of the disease. Most are designed to eradicate superficial lesions, not to cure the infection itself. This leads to a relatively high relapse rate and the necessity for alternative therapy. Choice of treatment can be dependent on many factors, includi…
Diagnosis
- HPV tests are available to detect oncogenic types of HPV infection and are used in the context of cervical cancer screening and management or follow-up of abnormal cervical cytology or histology (see Cervical Cancer, Screening Recommendations). These tests should not be used for male partners of women with HPV or women aged <25 years, for diagnosis of genital warts, or a…
- Your doctor usually can diagnose warts by examining the area. By looking at the area, your doctor also can determine what treatment may be necessary. In general warts don't need to be biopsied. However, if your doctor is concerned that the changes could be cancerous, a skin biopsy may be needed. In a biopsy, a small piece of tissue is removed and examined under a microscope. Peop…
- Your doctor will make a diagnosis of skin or genital warts based on a physical exam. Sometimes, your doctor may perform a biopsy (removal of a small tissue sample) to properly diagnose genital warts and eliminate other skin conditions that may be causing the symptoms.To diagnose and test for precancerous lesions in women, your doctor will perform a Pap smear. This test can det…
Causes
- HPV is easily spread from sexual skin-to-skin contact with someone who has it. You get it when your vulva, vagina, cervix, penis, or anus touches someone elses genitals or mouth and throat usually during sex. HPV can be spread even if no one cums, and even if a penis doesnt go inside the vagina/anus/mouth.
- HPV enters the body, usually through a break in the skin, and then infects the cells in the layers of the skin. The virus then replicates or multiplies in the body. The time between first contracting HPV and the appearance of lesions can be weeks to months or even years. Many people don't even know they are infected with HPV.HPV is usually transmitted by skin-to-skin contact. HPV in…
Prevention
- There are several HPV vaccines licensed in the United States: a bivalent vaccine (Cervarix) that prevents infection with HPV types 16 and 18, a quadrivalent vaccine (Gardasil) that prevents infection with HPV types 6, 11, 16, and 18, and a 9-valent vaccine that prevents infection with HPV types 6, 11, 16, and 18, 31, 33, 45, 52, and 58. The bivalent and quadrivalent vaccines offer prote…
- There are two FDA approved vaccines against human papillomavirus, Gardasil and Cervarix. Both vaccines are approved for females to help prevent cervical cancer. The general recommendation is to vaccinate 11 and 12 year old girls with either vaccine. Girls as young as 9 years old may receive the vaccine. A complete series consists of three shots over 6 months. The same vaccin…
- A positive test for HPV mostly indicates that you should be conscientious about regular Pap smears. These screen for cervical dysplasia and early signs of cervical cancer. Keeping up to date on the screening is important because your risk is higher than women who have not been infected with HPV. However, only a small fraction of even women with persistent HPV will ever develop c…
- An HPV test is a way to prevent cervical cancer in women 30 and older. During this test, a member of the health care team takes a sample of cells from the woman’s cervix. This sample is tested for the types of HPV most commonly linked to cervical cancer. HPV testing may be done by itself or combined with a Pap test. This test involves gathering a sample of cells from the cervix to look f…
Symptoms
- It is possible to have an HPV skin or genital infection without having symptoms. When an HPV infection does cause a wart, the appearance varies slightly depending on its location: 1. Common skin warts — These most often affect the hands, face, skin or scalp, and are especially common on sites of previous skin injury. They are small (about 6 millimeters or one-fourth of an inch), fir…
- Most HPV infections go unnoticed because they don't cause any symptoms. The virus may have been contracted years ago and it can remain in the body for weeks, years, or even a lifetime without showing any symptoms of an infection.For those who experience symptoms, the type of symptoms depends on the type of HPV infection. 1. Common warts are painless, firm growths w…
Results
- Results from your HPV test will come back as either positive or negative. 1. Positive HPV test. A positive test result means that you have a type of high-risk HPV that's linked to cervical cancer. It doesn't mean that you have cervical cancer now, but it's a warning sign that cervical cancer could develop in the future. Your doctor will probably recommend a follow-up test in a year to see if th…
- If you're positive for HPV, it does indicate a need for follow-up. That's particularly true if that positive HPV test occurs in combination with an abnormal Pap smear. However, it does not indicate a need for panic. It may not even mean that you need a Pap smear more often than once a year. Your overall risk of getting cervical or other HPV cancers is higher than someone withou…
- Table 1 represents the basic demographic and behavioral variables of the study population. The age of the study population was normally distributed within the eligible age range of 35–60 years, with a mean age (±SD) of 46.6 ± 6.7 years. The population was 74.3% white and 19.0% black, and the remaining women were Asian or another race. The majority of women in the population had …
Epidemiology
- Genital HPV infections are very, very common. In fact, most people who have sex get the HPV at some point in their lives. Most people with HPV have no symptoms and feel totally fine, so they usually dont even know theyre infected.
- HPV infection is responsible for most, if not all, cervical cancer cases. It's also responsible for genital warts and other forms of cancer in both women and men. However, most women who are infected with HPV will never develop cervical cancer. In fact, more than 70 percent of women who receive a positive test for HPV will clear the infection and test negative again within two years. O…
- Non-Hispanic Asian adults had the lowest prevalence of any and high-risk genital HPV infection among the total population, as well as among men and women, whereas non-Hispanic black adults had the highest prevalence of any and high-risk genital HPV infection among both the total population and among men and women. Men had more genital and high-risk genital HPV infecti…
Prognosis
- The outlook varies. Many common warts disappear without treatment over 6 to 12 months. Others dissolve when an over-the-counter remedy is used for several weeks or months. Of the office-based therapies, surgical removal of a wart gives the best immediate results, because the wart is cut away in one doctor's visit. Other forms of therapy require several office visits. After a …
- Most genital HPV infections arent harmful at all and go away on their own. But some kinds of HPV can lead to genital warts or certain types of cancer.
Further Information
- Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Medical Disclaimer...
- Centers for Disease Control and Prevention: Human Papillomavirus (HPV)National Cancer Institute: HPV and CancerLab Tests Online: HPV Test...