Medication
Major depressive disorder is a serious condition, but it is treatable. It may take some time to find the right approach for your needs, but understanding what you can expect in terms of treatment effects can help you better recognize how your treatment is working. Was this page helpful? Thanks for your feedback!
Therapy
Because there are many factors that can contribute to major depressive disorder, treatment approaches can vary, so there is no single way to treat it. Because there is no “one-size-fits-all” treatment, your individual experience may vary.
Self-care
Despite the sometimes-crippling symptoms, major depression is manageable and treatable; with medication, therapy, or both, people can recover and lead happy, fulfilling lives. What Is Major Depressive Disorder? Major depressive disorder is a serious mental illness that affects how people feel, think, and go about their everyday tasks.
Is major depressive disorder treatable?
Exercise as a treatment for depression: A meta-analysis. Journal of Affective Disorders. Mandal, S., et al. (2019). Efficacy of ketamine therapy in the treatment of depression. Indian Journal of Psychiatry. Markowitz, J., et al. (2004). Interpersonal psychotherapy: principles and applications. World Psychiatry.
How is major depressive disorder (MDD) treated?
Can You recover from major depressive disorder?
What is the best treatment for depression in adults?

What is the success rate of treatment for depression?
New Stanford Medicine Study Finds a 90% Success Rate for Depression.
What is one effective treatment for major depressive disorder?
Psychotherapy, or traditional talk therapy, is an effective treatment for major depressive disorder.
What is the most effective therapy for major depressive disorder?
Compared with usual care, treatment with structured psychotherapy (CBT or interpersonal therapy) represents good value for money for adults with major depressive disorder and/or generalized anxiety disorder.
What is the most effective treatment for depressive disorders in the short term?
The only treatment for depression that has an immediate therapeutic effect is sleep deprivation, which can be done on an inpatient or outpatient basis.
What are the 2 types of treatment for major depressive disorder?
There are several treatment methods for major depression disorder. These approaches include psychotherapy, antidepressant medications, electroconvulsive treatment (ECT), and other somatic therapies. However, ECT is generally avoided, except in extreme circumstances, in favor of both psychotherapy and antidepressants.
Is depression a treatable condition?
Depression is among the most treatable of mental disorders. Between 80% and 90% percent of people with depression eventually respond well to treatment. Almost all patients gain some relief from their symptoms.
What kind of therapy is used to treat depression?
Cognitive Behavioral Therapy (CBT) Cognitive behavioral therapy, or CBT, helps an individual identify and change negative thoughts and associated behaviors. People who suffer from depression often struggle with negative thought patterns. These thought patterns can influence our behavior.
What is the latest treatment for depression?
On March 5, 2019, the Food and Drug Administration (FDA) approved the first new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine—an anesthetic that has made waves for its surprising antidepressant effect.
What are two benefits of having support while dealing with depression?
Improved sense of belonging and security. Spending time with people and knowing you're not alone reduces feelings of isolation and loneliness. Having people to reach out to in a time of need can be comforting.
Which of the following treatments is most likely to be used only with severely depressed patients who have not responded to drug therapy?
Electroconvulsive therapy (ECT) is a medical treatment most commonly used in patients with severe major depression or bipolar disorder that has not responded to other treatments.
What happens when ECT doesn't work?
If nothing else has helped, including ECT, and you are still severely depressed, you may be offered neurosurgery for mental disorder (NMD), deep brain stimulation (DBS) or vagus nerve stimulation (VNS).
Is depression cured completely?
There's no cure for depression, but there are lots of effective treatments. People can recover from depression and live long and healthy lives.
How to help depression?
But in addition to professional treatment, these self-care steps can help: Stick to your treatment plan. Don't skip psychotherapy sessions or appointments. Even if you're feeling well, don't skip your medications.
How to deal with depression and change behaviors?
Identify negative beliefs and behaviors and replace them with healthy, positive ones. Explore relationships and experiences, and develop positive interactions with others. Find better ways to cope and solve problems. Identify issues that contribute to your depression and change behaviors that make it worse.
What is the term for depression that begins a week before your period?
Premenstrual dysphoric disorder. This involves depression symptoms associated with hormone changes that begin a week before and improve within a few days after the onset of your period, and are minimal or gone after completion of your period. Other depression disorders.
What tests can a doctor do for depression?
Your doctor may do a physical exam and ask questions about your health. In some cases, depression may be linked to an underlying physical health problem. Lab tests. For example, your doctor may do a blood test called a complete blood count or test your thyroid to make sure it's functioning properly. Psychiatric evaluation.
Why do people need hospitalization for depression?
This may be necessary if you can't care for yourself properly or when you're in immediate danger of harming yourself or someone else. Psychiatric treatment at a hospital can help keep you calm and safe until your mood improves.
Can depression therapy be done online?
Formats for depression therapy as an alternative to face-to-face office sessions are available and may be an effective option for some people. Therapy can be provided, for example, as a computer program, by online sessions, or using videos or workbooks. Programs can be guided by a therapist or be partially or totally independent.
Can you go to the hospital for depression?
However, many people with depression also benefit from seeing a psychiatrist, psychologist or other mental health professional. If you have severe depression, you may need a hospital stay, or you may need to participate in an outpatient treatment program until your symptoms improve.
What is major depressive disorder?
Depression is a serious mood disorder that can cause many symptoms, including feelings of numbness, emptiness, and sadness. It can cause withdrawal from normal activities and impact close relationships, school, and work.
What types of therapy can be used for depression?
Psychotherapy can be an essential part of treatment for major depression. It may be used on its own or together with antidepressant medication. Psychotherapy may help within a few weeks. Or, it can take longer depending on your situation.
What medications can be prescribed for depression?
There are many antidepressant medications to treat depression. You and your provider will work together to find a medication or combination of medications that reduce your symptoms. The types of medications used to treat depression include:
What natural treatments can help for major depressive disorder?
Some natural and over-the-counter supplements may help for depression. It’s important to note that while these may help some mild forms of depression, they likely will not be effective in treating major depression.
What lifestyle changes might help treat major depressive disorder?
There are some important lifestyle changes and daily habits that can help manage your depression symptoms. These include:
Where can you find healthcare providers for depression treatment?
If you think you may have depression, reach out to a healthcare provider. You can start with your primary care provider (PCP). They might be able to provide a referral to a qualified mental health professional.
The bottom line
Depression is one of the most common mental health conditions. It will likely impact you or someone you love at some point in your life. While it may be scary or overwhelming to seek help for depression, it’s important to know that many treatment options are available.
How to manage depression?
These healthy lifestyle habits, along with professional treatment, can help you manage the symptoms of major depression: Focus on self-care. Control stress with activities such as meditation or tai chi. Eat healthy, exercise, and get enough sleep. Most adults need 7-9 hours of sleep per night.
How to treat depression and anxiety?
Set realistic goals to build confidence and motivation. A goal at the beginning of treatment may be to make your bed, have lunch with a friend, or take a walk.
How long does depression last?
Major depressive disorder isn’t something that eventually “passes.”. While most people feel sad at times in their lives, major depression is when a person is in a depressed mood most of the day, nearly every day, for at least two weeks.
How does postpartum depression affect women?
Postpartum Depression affects women after having a baby. It causes intense, long-lasting feelings of anxiety, sadness, and fatigue, making it difficult for mothers to care for themselves and/or their babies, as well as handle daily responsibilities.
What is the meaning of "major depressive disorder"?
Major depressive disorder is a serious mental illness that affects how people feel, think, and go about their everyday tasks. The condition can also impact a person’s sleep habits, appetite, and ability to enjoy life. Major depressive disorder isn’t something that eventually “passes.”.
How long does it take for depression to start after childbirth?
Postpartum depression can start anywhere from weeks to months after childbirth. Psychotic Depression is a form of depression with psychosis, such as delusions (false beliefs) and/or hallucinations (hearing or seeing things that are not there). Seasonal Affective Disorder is triggered by changes in seasons.
How long does it take to get diagnosed with major depression?
To receive a diagnosis of major depressive disorder, some of these signs and symptoms must be present for at least two weeks. Anyone who has questions should consult their doctor. Continued feelings of sadness, hopelessness, pessimism, emptiness.
How does major depressive disorder affect your life?
Major depressive disorder can disrupt nearly every facet of your daily life, including your ability to sleep and wake up, eat, communicate, work, maintain healthy relationships, and care for yourself and your loved ones.
Which medical conditions are associated with higher rates of depression?
Certain medical conditions: Some medical conditions, such as thyroid conditions, sleep disorders, and certain cancers are associated with higher rates of depression. 14
How many people have a major depressive episode?
According to 2017 statistics from the National Institute of Mental Health (NIMH), 7.1% of adults in the United States—roughly 17.3 million—had at least one major depressive episode. Women were more likely to be affected than men (8.7% versus 5.3% respectively). 2 .
What is depression in psychology?
Diagnosis. Causes. Treatment. Coping. Depression is a common and serious mood disorder that impacts the way an individual feels, thinks, and acts on a daily basis. It also goes by the name major depressive disorder (MDD), or clinical depression.
How much of the time does genetics determine if someone is depressed?
Genetics: A family history of depression is common in those suffering from the condition. Research suggests that approximately 40% of the time genetics determines whether or not someone will become depressed. 12
How many children have depression?
What's more, depression is not only common in adults. In fact, an estimated 3.2% of children aged 3 to 17 have diagnosed depression, according to the Centers for Disease Control and Prevention (CDC). 5
What does it mean when someone is depressed?
Someone who is depressed may experience a lack of interest and excitement in everyday activities that they once enjoyed , and the overall emotional toll that depression can take on a person’s wellbeing can lead to emotional, physical, and mental issues that can impact nearly every facet of their life.
What is a QRG for treating major depressive disorder?
Treating Major Depressive Disorder: A Quick Reference Guide is asynopsis of the American Psychiatric Association’s Practice Guidelinefor the Treatment of Patients With Major Depressive Disorder, ThirdEdition, Part A of which was originally published in The American Jour-nal of Psychiatry in October 2010 and is available through AmericanPsychiatric Publishing, Inc. The psychiatrist using this Quick Refer-ence Guide (QRG) should be familiar with the full-text practice guide-line on which it is based. The QRG is not designed to stand on its ownand should be used in conjunction with the full-text practice guide-line. For clarification of a recommendation or for a review of the ev-idence supporting a particular strategy, the psychiatrist will find ithelpful to return to the full-text practice guideline.
When was the 3rd edition of Major Depression published?
Based on Practice Guideline for the Treatment of Patients With MajorDepressive Disorder, Third Edition, originally published in October2010. A guideline watch, summarizing significant developments inthe scientific literature since publication of this guideline, may beavailable.
What is the best treatment for depression?
Psychological counseling. Psychological counseling (psychotherapy) by a psychiatrist, psychologist or other mental health professional can be very effective. For many people, psychotherapy combined with medication works best. It can help identify underlying concerns that may be adding to your depression.
What type of therapy is used to help with depression?
Interpersonal psychotherapy focuses on resolving relationship issues that may contribute to your depression. Family or marital therapy. This type of therapy involves family members or your spouse or partner in counseling. Working out stress in your relationships can help with depression.
What is ECT therapy?
Electroconvulsive therapy (ECT). While you're asleep, a carefully measured dose of electricity is passed through your brain, intentionally triggering a small, brief seizure. ECT seems to cause changes in brain chemistry that can relatively quickly reverse symptoms of major depression. Although there are potential side effects, such as temporary confusion or temporary memory loss, a series of ECT treatments may provide significant relief of severe depression.
What to ask a psychiatrist about depression?
Consider your response to treatment, including medications, psychotherapy or other treatments you've tried.
What to do if counseling doesn't work?
If counseling doesn't seem helpful, talk to your psychotherapist about trying a different approach. Or consider seeing someone else. As with medications, it may take several tries to find a treatment that works. Psychotherapy for depression may include:
What are some physical conditions that can cause depression?
Consider physical health conditions that can sometimes cause or worsen depression, such as thyroid disorders, chronic pain or heart problems
How to help someone with depression?
If you have trouble sleeping, research ways to improve your sleep habits or ask your doctor or mental health professional for advice. Get regular exercise. Exercise has a direct effect on mood. Even physical activity such as gardening or walking can reduce stress, improve sleep and ease depression symptoms.
What is the best treatment for depression?
Psychotherapy is another tool in your toolkit to manage depression. And it works for lots of people. Research shows most people who use psychotherapy find it helpful.
How to manage depression?
Your therapist will guide you through different strategies, including: Spotting warped, unhelpful thoughts and looking at them based in reality. Understanding others’ behaviors and impulses.
Why is group therapy important?
One of the benefits of group therapy is being with people dealing with the same things you’re dealing with. It can be helpful to know you’re not alone.
How long does it take to get a therapist to meet you?
You’ll usually meet at your therapist’s office once a week for 45 to 60 minutes, or in a group session if you’re in the hospital for treatment. But there are other options that may work just as well. These include: A mental health professional may lead these programs, or you may be able to do them on your own.
How many people are in a group therapy?
Group Therapy. In group therapy, five to 15 people focus on one specific medical problem like depression, or a general topic such as improving social skills. Led by one or more therapists, the group meets for 1-2 hours every week. Some people will also go to therapy on their own.
Is CBT better than medication?
Research shows CBT works just as well, or even better, than medication or other types of psychotherapy. The main ideas of CBT are: Mental health issues stem partly from negative thinking and behavior patterns you learn over time. You can learn how to manage these thoughts and behaviors to ease your depression symptoms.
Diagnosis
Treatment
Clinical Trials
Lifestyle and Home Remedies
Specialist to consult
Alternative Medicine
Coping and Support
- Medications and psychotherapy are effective for most people with depression. Your primary care doctor or psychiatrist can prescribe medications to relieve symptoms. However, many people with depression also benefit from seeing a psychiatrist, psychologist or other mental health professional. If you have severe depression, you may need a hospital st...
Preparing For Your Appointment
- Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
What Is Major Depressive Disorder?
- Depression generally isn't a disorder that you can treat on your own. But in addition to professional treatment, these self-care steps can help: 1. Stick to your treatment plan.Don't skip psychotherapy sessions or appointments. Even if you're feeling well, don't skip your medications. If you stop, depression symptoms may come back, and you could also experience withdrawal-like symptoms. Recognize that it will take time to feel better. 2. Learn about de…
Symptoms
- Alternative medicine is the use of a nonconventional approach instead of conventional medicine. Complementary medicine is a nonconventional approach used along with conventional medicine — sometimes called integrative medicine. Make sure you understand the risks as well as possible benefits if you pursue alternative or complementary therapy. Don't replace conventional medical treatment or psychotherapy with alternative medici…
Diagnosis
- Talk with your doctor or therapist about improving your coping skills, and try these tips: 1. Simplify your life.Cut back on obligations when possible, and set reasonable goals for yourself. Give yourself permission to do less when you feel down. 2. Write in a journal.Journaling, as part of your treatment, may improve mood by allowing you to express pain, anger, fear or other emotions. 3. Read reputable self-help books and websites.Your doctor or th…
Causes
- You may see your primary care doctor, or your doctor may refer you to a mental health professional. Here's some information to help you get ready for your appointment.
Treatment
Coping
- These are the most common signs and symptoms associated with major depressive disorder, according to the National Institute of Mental Health:3 1. Persistent sadness, anxious, or “empty” mood 2. Feelings of hopelessness, or pessimism 3. Irritability 4. Feelings of guilt, worthlessness, or helplessness 5. Loss of interest or pleasure in hobbies and activities 6. Decreased energy or fatigue 7. Moving or talking more slowly 8. Feeling restless or havi…