How long does it take to get dexamethasone for croup?
Of the patients that had a prehospital diagnosis of croup (n=66), only 10.6% (n=7) received dexamethasone in the prehospital setting. The mean time from EMS arrival at home to EMS arrival at the ED was 40±22 minutes (n=155). The mean time from arrival via EMS at the ED to triage was 8±5 minutes (n=153).
How many milligrams of croup medicine should I take?
Some studies suggest lower doses (0.15-0.3 mg/kg) may be effective for mild croup, but the data is limited. For this reason, we recommend using the standard 0.6 mg/kg) dose in this guideline. 7. Onset in 1 hour.
Does prehospital dexamethasone increase ed Los in croup?
For patients who had a prehospital diagnosis of croup, there was no statistically significant difference in ED LOS between those who received prehospital dexamethasone and those who did not (P=0.458).
Which medications are used in the treatment of croup in children?
The disposition of children with croup treated with racemic epinephrine and dexamethasone in the emergency department. J Emerg Med. 1998;16(4):535–539.
How long does Decadron last?
How long do dexamethasone side effects last? With a half-life of four hours (the amount of time it takes the body to eliminate half a dose), a 20 mg dose is eliminated from the body in about 24 hours.
How quickly does Decadron work?
6. Response and effectiveness. Peak effects of dexamethasone are reached within 10 to 30 minutes of administration; however, it may take a couple of days before any inflammation is well controlled.
How long does croup last after treatment?
2. How long does Croup last? - Croup often runs its course within 3 to 4 days. Your child's cough may improve during the day, but don't be surprised if it returns at night.
How long does Decadron last in kids?
Prolonged treatment course, vomiting and a bitter taste may reduce patient compliance with prednisolone. Dexamethasone is a long-acting corticosteroid with a half-life of 36 to 72 hours. It is used frequently in children with croup and bacterial meningitis, and is well absorbed orally.
Does dexamethasone work right away?
There was a growing trend to a lower croup score in the dexamethasone group, evident from 10 min and statistically significant from 30 min. Conclusion: For children with croup an oral dose of 0.15 mg/kg dexamethasone offers benefit by 30 min, much earlier than the 4 h suggested by the Cochrane Collaboration.
Is Decadron a strong steroid?
Yes, dexamethasone is considered a strong corticosteroid. It is a long-acting corticosteroid that is about 25 times more potent (stronger) than hydrocortisone and 6 times more potent than prednisone. For reference, your body naturally makes the equivalent of about 5 mg prednisone daily.
Why does croup get worse at night?
Croup can occur any time of day, but it is usually worse at night because the body's natural steroid levels fall at night, making the swelling of the voice box worse.
Does croup get worse at night?
The swelling narrows the trachea, which makes it harder for air to get into the lungs. It often starts as a “cold.” Croup can cause a barky cough or hoarse voice and is usually worse at night.
What helps a croup cough at night?
Lifestyle and home remediesStay calm. Comfort or distract your child — cuddle, read a book or play a quiet game. ... Provide humidified or cool air. ... Hold your child in a comfortable upright position. ... Offer fluids. ... Encourage rest. ... Try a fever reducer. ... Skip the cold medicines.
How long does dexamethasone stay in system?
Dexamethasone is known as a long-acting drug. Its half-life is 36-72 hours.
When do you give dexamethasone for croup?
A single dose of dexamethasone has been shown to be effective in reducing the overall severity of croup, if administered within the first 4-24 hours after the onset of illness.
What's the half-life of dexamethasone?
The biological half-life of dexamethasone is 36 - 54 hours; therefore, dexamethasone is especially suitable in conditions where continuous glucocorticoid action is desirable.
Usual Adult Dose for Acute Mountain Sickness
Prevention of AMS and HACE: Usual dose: 2 mg orally every 6 hours OR 4 mg orally every 12 hours -Very High Risk Situations (e.g.
Usual Adult Dose for Cerebral Edema
Initial dose: 10 mg IV once, followed by 4 mg IM every 6 hours until maximal response is noted -After 2 to 4 days, dose should be reduced and then gradually discontinued over a period of 5 to 7 days Comments: -After symptoms subside, may switch to oral therapy (1 to 3 mg orally 3 times a day) and then taper gradually over 5 to 7 days. -In patients undergoing brain surgery, may continue treatment for several days postoperatively. -In nonoperative cases, continuous therapy may be needed to remain symptom-free. Use: For the treatment of cerebral edema..
Usual Adult Dose for Cushing's Syndrome
Dexamethasone Suppression Tests: -Short suppression test: 1 mg orally at 11 PM; draw plasma cortisol at 8 AM the following morning -Long suppression test: 0.5 mg orally every 6 hours for 48 hours; 24-hour urine collections are made before, during, and at the end of the test for determination of 17-hydroxycorticosteroids -Test to distinguish Cushing's syndrome: 2 mg orally every 6 hours for 48 hours; 24-hour urine collections are made before, during, and at the end of the test for determination of 17-hydroxycorticosteroids Comment: The long suppression test provides greater accuracy in diagnosing Cushing's syndrome. Uses: Diagnostic testing for Cushing's syndrome..
Usual Adult Dose for Shock
Unresponsive shock: 1 to 6 mg/kg IV as a single dose or up to 40 mg initially followed by repeat IV doses every 2 to 6 hours while shock persists Published protocols: 20 mg IV as a single dose followed by IV infusion of 3 mg/kg/24 hours 1 to 6 mg/kg IV as a single dose 40 mg IV as a single dose followed by repeat IV doses every 4 to 6 hours while shock persists Comments: -High-dose therapy should only be continued until patient's condition has stabilized and usually no longer than 48 to 72 hours. Use: For the treatment of unresponsive shock..
Usual Adult Dose for Multiple Myeloma
40 mg oral/IV on days 1, 8, 15, 22, and repeated every 4 weeks Comments: -This drug is a part of most major treatment regimens in multiple myeloma; treatment regimens should be consulted. -In regimens containing bortezomib, the day 1 dexamethasone dose may be split to provide 20 mg on the day of and 20 mg on the day after bortezomib. -Doses may need to be adjusted for performance status or other toxicities Use: For the treatment of multiple myeloma..
Usual Adult Dose for Multiple Sclerosis
Acute exacerbation: 30 mg orally once a day for 1 week followed by 4 to 8 mg orally every other day for 1 month Comments: -Short-term high-dose corticosteroids are an accepted standard of care for treating relapses of multiple sclerosis; chronic daily corticosteroids are not recommended. -IV methylprednisolone, oral prednisone and prednisolone are the corticosteroids most studied and cited in clinical guidelines; while this drug has been used, efficacy studies and comparative data are lacking. Use: For the treatment of acute exacerbations of multiple sclerosis..
Usual Adult Dose for Anti-inflammatory
Dosing should be individualized on the basis of disease and patient response Oral: -Initial dose: 0.75 mg to 9 mg orally per day Parenteral: -Initial dose: 0.5 mg to 9 mg IV or IM per day in divided doses every 12 hours Maintenance dose: After a favorable initial response, dose should be decreased in small amounts to the lowest dose that maintains an adequate clinical response; if a positive response is not achieved after a reasonable period of time, alternative therapy should be sought. Comments: -Lower doses, including doses lower than recommended doses, may suffice in less severe disease; doses in excess of recommended doses may be required in severe disease; in life-threatening situations, doses exceeding multiples of the oral dose may be justified. -When oral therapy is not feasible IV or IM therapy in doses ranging from one-third to one-half the oral dose may be given every 12 hours. -Patients should be closely monitored for signs requiring dose adjustments; if therapy is to be stopped after more than a few days, it should be gradually withdrawn. Uses: For use as a potent anti-inflammatory agent in managing disorders, diseases, and conditions affecting many organ systems including endocrine, dermatologic, ophthalmic, nervous.