Treatment FAQ

how long to feel normal after vitamin d deficiency treatment guidelines

by Gardner Von Published 3 years ago Updated 2 years ago

Full Answer

How long does it take to feel the effects of vitamin D?

How long it takes for you to feel the effects of your vitamin D supplement depends on the severity of your deficiency. It may take weeks or months. Your doctor will monitor your blood levels of vitamin D and adjust your dose accordingly.

How do you know if you have a vitamin D deficiency?

Having a vitamin D deficiency can leave you feeling tired, weak and depressed. If you suspect your levels are low, talk to your doctors. They'll create a plan to improve your vitamin D levels within a few months. You'll start feeling better after your vitamin D supplements take effect — just give it a few months.

When should I recheck my vitamin D levels?

A patient with a 25(OH)D level of 10 ng/mL who is beginning treatment with 50,000 IU of vitamin D 3 times weekly for 1 month to be followed by 50,000 IU once monthly should be rechecked after 1 month A patient with a 25(OH)D level of 10 ng/mL who is beginning treatment with 2000 IU/d of D3should be rechecked after 6 months

Will a vitamin D supplement Make you Feel 100% again?

Vitamin D is NOT a magic bullet that makes everyone feel 100% again when their levels are corrected. While it CAN and HAS done that, that is the exception and not the rule. So, make sure that you get another Vitamin D Level in a few more weeks and see what it is.

What Does Vitamin D Do?

In boring chemical terms, vitamin D helps regulate the amount of phosphate and calcium in the body, both of which are central to bone strength and...

Should You Take Vitamin D Supplements?

Because of the many benefits that vitamin D offers and the low risk of overdosing, we believe that vitamin D supplements would be beneficial for mo...

How Long Does Vitamin D Take to Work?

Unfortunately, there’s no definite answer on how quickly vitamin D takes effect on the body, as various factors like dosage and existing vitamin D...

How Long Does Vitamin D Take to Work?

If you’re battling a serious vitamin D deficiency, then it could take a month of daily supplements before you start to feel normal again.

What are the symptoms of low vitamin D levels?

Aside from a general meh feeling, symptoms of low vitamin D levels can include fatigue, muscle pain and regular periods of sickness. If you’re struggling to get out of bed or coming down with the sniffles more than usual, it could be nothing, but keep an eye out for the following 8 symptoms of vitamin D deficiency:

What foods contain vitamin D?

Oily Fish: As well as being high in protein and omega-3 (which is good for cardiovascular health), oily fish such as salmon, mackerel and tuna contain vitamin D. If you’re concerned about a potential vitamin d deficiency, mix up your menu plan with some of the suggestions below and enjoy dinners as tasty as they are healthy:#N#Salmon – try with sweet chilli sauce and stir-fried veggies for an Asian-inspired supper#N#Mackerel – mix tinned mackerel with mashed potato for cheap and cheerful fishcakes.#N#Sardines – fry and stir through passata to make an Italian-inspired pasta sauce.#N#Tuna – the classic store-cupboard staple is incredibly versatile in pasta, sandwiches and more.#N#Swordfish – if you’re feeling fancy, char-grill swordfish steaks and serve with mango salsa 1 Salmon – try with sweet chilli sauce and stir-fried veggies for an Asian-inspired supper 2 Mackerel – mix tinned mackerel with mashed potato for cheap and cheerful fishcakes. 3 Sardines – fry and stir through passata to make an Italian-inspired pasta sauce. 4 Tuna – the classic store-cupboard staple is incredibly versatile in pasta, sandwiches and more. 5 Swordfish – if you’re feeling fancy, char-grill swordfish steaks and serve with mango salsa

How to get vitamin D?

The Sun: Our fiery friend in the sky is still the number one way to get the recommended amount of vitamin D, especially in warmer climates and during the summer. Our bodies will naturally produce vitamin D when exposed to UV rays from the sun, but make sure you sun responsibly and top up your levels with vitamin D supplements when the sun is weaker in winter.

Why is vitamin D deficiency more common in winter months?

When you consider that vitamin d deficiency and seasonal depression are more common in the winter months due to reduced sunlight, it seems kinda obvious. Impaired Healing: Studies suggest that vitamin D’s role in controlling inflammation and fighting infection boosts healing, meaning that really slow healing may indicate a shortage of the vitamin.

What happens if you don't get enough vitamin D?

If you aren’t able to restore vitamin D levels from sunlight or your diet, then you may be at greater risk from a vitamin D deficiency.

What is the best way to get vitamin D?

Vitamin D Supplements: If you can’t be bothered with salmon fillets and long walks in the sun (there’s no shame in a few casseroles and cozy days over winter), then a simple supplement or two is the way to go. There are tons of supplements on the market which will help you meet your daily vitamin D requirements, so if you struggle to get the natural sources of vitamin D, you can still get your essential nutrients from a bottle.

What are the symptoms of vitamin D deficiency?

Symptoms of vitamin D deficiency can be rather nonspecific and include fatigue, altered mood and depression, insomnia, nonradicular back pain, arthralgias (particularly of the wrists, ankles, shoulders, and shins), proximal muscle weakness, headache, and hair loss.76,77Symptoms are uncommon with 25(OH)D levels greater than 20 ng/mL, and even individuals with mild to moderate deficiency may not spontaneously complain of symptoms unless they are undergoing treatment that results in reduced formation of 1,25(OH)2D or decreased vitamin D receptor activation, such as estrogen depletion as the result of aromatase-inhibitor therapy. In a pilot study, we found that 50,000 IU of vitamin D3 weekly for 12 weeks was effective in treating vitamin D insufficiency in women receiving the aromatase inhibitor letrozole, and higher levels of 25(OH)D were associated with reduced disability from aromatase inhibitor–associated joint pain.78

What is vitamin D adequacy?

Vitamin D adequacy is currently defined as a function of calcium homeostasis, with lower vitamin D levels resulting in reduced absorption of calcium from the gut and/or elevations of parathyroid hormone (PTH) considered in adequate. Blood levels of the prohormone 25(OH)D, with a half-life of 2 to 3 weeks, are used to describe vitamin D sufficiency rather than levels of 1,25(OH)2D, which has a half-life of only 3 to 4 hours.54,58Furthermore, in early vitamin D depletion, blood levels of 1,25(OH)2D can be misleading because they may rise initially in response to elevations in PTH, which is sensitive to reductions in 25(OH)D, before they begin to fall with prolonged precursor depletion.51,63

How much vitamin D is needed for bone health?

Vitamin D sufficiency is defined in terms of the serum level of the prohormone 25(OH)D required for bone health, which is 30 to 32 ng/mL. Maintenance of a 30 to 32 ng/mL serum level requires approximately 2,200 to 3,000 IU/d of vitamin D from all sources, including ultraviolet light exposure, food, and supplements.20,51,52Recommendations from the Institute of Medicine for vitamin D supplementation suggest 200 IU of vitamin D daily from birth through age 50 years, 400 IU/d for individuals age 51 to 70 years, and 600 IU/d for those age 70 years or older.53These recommendations presume some sun exposure and vitamin D intake from food and are not adequate to treat vitamin D deficiency.54,55Historically, the source of most vitamin D has been ultraviolet light–induced skin manufacture of cholecalciferol. A single whole-body dose of ultraviolet radiation associated with minimal erythema produces 10,000 IU of vitamin D.55Thus, 15 to 20 minutes of daily sun exposure without sunscreen in lower midwestern and southern latitudes between 10:00 amand 3:00 pmis usually sufficient to ensure adequate synthesis of vitamin D metabolites. Large excesses of vitamin D3 from prolonged sun exposure are destroyed in the skin, making vitamin D toxicity from sun exposure improbable.54,55In contrast, with the exception of coldwater ocean fish, food is a poor source of vitamin D.54Three ounces of herring, which few individuals eat, provides 1,300 IU of vitamin D, 3.5 oz of the more commonly ingested salmon provides 350 IU, and 1 teaspoon of cod liver oil provides approximately 400 IU. However, the amount of vitamin D in 1 cup of fortified milk or orange juice is only 100 IU, with 50-100 IU per cup of breakfast cereal or tablespoon of margarine.54,56,57Today, with more time spent indoors and increased use of sunscreen, higher basal intakes of 1,000 to 2,000 IU/d from supplements are recommended to avoid vitamin D deficiency.23,58–60Multiple vitamins generally contain 400 IU of vitamin D, and calcium supplements provide 200 to 400 IU of vitamin D. Vitamin D3 supplements without other additives are readily available over the counter in 400, 1,000, and 2,000 IU strengths at pharmacies and most grocery stores. These supplements are much smaller in size than pills containing calcium and vitamin D and generally cost $10 or less for a 3-month supply. At similar doses, vitamin D3 may be more potent than vitamin D2 (ergocalciferol), which is obtained from plants.61The Institute of Medicine lists 2,000 IU/d as the upper tolerable limit, but in fact, there is little evidence of toxicity unless doses of 10,000 IU of vitamin D3/d are exceeded.53,62

What is the role of vitamin D in the body?

Vitamin D plays an important role in the homeostasis of a variety of organ systems, but its role in prevention of cancer and recurrence—along with necessary blood levels —has yet to be defined.

Why is vitamin D important?

Vitamin D is important in a number of physiologic processes, including calcium absorption, innate and adaptive immunity, and homeostasis of a number of organs. Chronic vitamin D deficiency in adults results in osteoporosis, osteomalacia, muscle weakness, and increased risk of falls.1–4Poor vitamin D intake and low blood levels of vitamin D metabolites are associated with increased incidence and severity of several autoimmune diseases involving the T helper type 1 lymphocyte,5,6including multiple sclerosis,7rheumatoid arthritis,8type I diabetes,9systemic lupus erythematosis,10and psoriasis.11,12Lower levels of vitamin D, adjusted for body mass index, are also associated with increased risk of hypertension, myocardial infarction, and death as a result of cardiovascular disease.13–16

What does a U mean in ASCO disclosure declaration?

Certain relationships marked with a “U” are those for which no compensation was received ; those relationships marked with a “C” were compensated. For a detailed description of the disclosure categories, or for more information about ASCO's conflict of interest policy, please refer to the Author Disclosure Declaration and the Disclosures of Potential Conflicts of Interest section in Information for Contributors.

What is the recommended level of 25(OH)D?

At the present time, 25(OH)D levels in the range of 30 to 60 ng/mL are considered optimal, but higher levels up to 100 ng/mL are often seen in individuals with outdoor occupations receiving intense sun exposure without ill effects.55Correlative studies of 25(OH)D with muscle strength or risk of breast or colon cancer have prompted several investigators to suggest that the optimal 25OHD target for multiple health outcomes is 40 to 50 ng/mL.19,20Garland et al23suggest that increasing 25(OH)D to a range of 40 to 60 ng/mL from the current US average could reduce risk of breast cancer by 25% and colon cancer by 27%. Intakes of at least 4,000 IU daily from all sources would be needed to maintain 25(OH)D levels of 40 to 60 ng/mL. Practically speaking, supplements of 2,000 IU daily plus some sun exposure would probably be required to maintain a 25(OH)D level of 40 to 60 ng/mL year round.23

What to do after vitamin D levels go back to normal?

After your levels have gone back to normal, you may need to continue to take a vitamin D supplement. Take your medicine as directed. Contact your healthcare provider if you think your medicine is not helping or if you have side effects. Tell him of her if you are allergic to any medicine.

How long does it take for vitamin D to increase?

High-dose vitamin D supplements may be needed for 8 to 12 weeks to increase your levels. Your levels will then be rechecked. If your levels are still low, you will need to take vitamin D supplements for another 8 weeks. After your levels have gone back to normal, you may need to continue to take a vitamin D supplement.

What foods can you eat to prevent vitamin D deficiency?

Prevent vitamin D deficiency: Eat foods that are high in vitamin D. Fatty fish such as mackerel, canned tuna and sardines, and salmon are good sources of vitamin D. Eggs, almonds, and meat such as liver are also good sources. Certain foods such as milk, juice, and cereal are fortified with vitamin D. Give your breastfed infant a vitamin D ...

What is vitamin D deficiency?

WHAT YOU NEED TO KNOW: Vitamin D deficiency is a low level of vitamin D in your body. Vitamin D helps your body absorb calcium from foods. Your body makes vitamin D when your skin is exposed to sunlight. You can also get vitamin D from certain foods. Most of the vitamin D in your body comes from sunlight exposure.

Is vitamin D toxic?

High doses of vitamin D can be toxic. Your healthcare provider will tell you how much vitamin D you should take each day. Vitamin D is best absorbed when taken with food. Expose your skin to sunlight as directed. Ask your healthcare provider how you can safely expose your skin to sunlight and for how long.

What is the best vitamin for deficient patients?

Treatment with either vitamin D2 or vitamin D3 was recommended for deficient patients.

Is vitamin D deficiency common in all age groups?

Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recommended supplementation at suggested daily intake and tolerable upper limit levels, depending on age and clinical circumstances.

What is the best way to determine vitamin D adequacy?

Vitamin D adequacy is best determined by measurement of the 25-hydroxyvitamin D concentration in the blood.

How much vitamin D should I take daily?

Since 1997, the Food and Nutrition Board has advised an AI of vitamin D of 200 to 600 IU/d.18The AI is “believed to cover the needs of all individuals” but “lack of data or uncertainty in the data” limit the ability to confidently determine a recommended daily allowance. The AI for vitamin D is based on maintenance of a total serum 25(OH)D level of at least 11 ng/mL.18Although these recommendations are the basis for the amounts of vitamin D used to fortify foods and provided in many supplements, it is widely accepted that they are outdated.22Revised dietary reference intakes from the Institute of Medicine are expected in 2010.

What vitamin is needed for CKD?

Superimposed nutritional deficiency may aggravate secondary HPT both directly (as a result of low vitamin D levels) and indirectly (as a result of impaired vitamin D –mediated intestinal calcium absorption). Patients with stage I to III CKD should be tested and supplemented with vitamin D as needed to achieve optimal levels of 25(OH)D in addition to modifying calcium and phosphate intake. Emerging evidence is challenging our understanding of bone and vascular health in stage IV to V CKD, such that vitamin D, calcitriol, or vitamin D analogs should be used according to current CKD guidelines and under the guidance of a nephrologist.

How is vitamin D produced?

Vitamin D is produced by skin exposed to ultraviolet B radiation or obtained from dietary sources, including supplements. Persons commonly at risk for vitamin D deficiency include those with inadequate sun exposure, limited oral intake, or impaired intestinal absorption. Vitamin D adequacy is best determined by measurement of the 25-hydroxyvitamin D concentration in the blood. Average daily vitamin D intake in the population at large and current dietary reference intake values are often inadequate to maintain optimal vitamin D levels. Clinicians may recommend supplementation but be unsure how to choose the optimal dose and type of vitamin D and how to use testing to monitor therapy. This review outlines strategies to prevent, diagnose, and treat vitamin D deficiency in adults.

What is the best test for vitamin D?

Ingested and cutaneously produced vitamin D is rapidly converted to 25(OH)D, but in serum only a fraction of 25(OH)D is converted to its active metabolite 1,25(OH)2D. Thus, measurement of the total 25(OH)D level is the best test to assess body stores of vitamin D. The total 25(OH)D level allows for the diagnosis and monitoring of vitamin D deficiency, whereas quantification of 25(OH)D2and 25(OH)D3fractions may facilitate treatment monitoring. For example, in patients without clinical improvement after D2or D3supplementation, lack of increase in the corresponding 25(OH)D2or 25(OH)D3and total 25(OH) D levels may indicate inadequate dosing, nonadherence, or malabsorption. Some laboratory assays for vitamin D cannot differentiate between 25(OH)D2and 25(OH)D3and will only report a total 25(OH)D level. Some laboratory assays underdetect D2metabolites, which may give the appearance of ineffective D2supplementation.

How much vitamin D is needed for winter?

In northern latitude locations in particular, up to 73% of the population may have levels of less than 20 ng/mL during winter.16Thus, it is important to be aware that vitamin D levels are affected by both geographic and seasonal variability and that a person with an “optimal” level in the summer may well become “deficient” in the winter without any change in diet and as a result of changes in sun exposure.

How much calcium is absorbed by the body?

First, up to 500 to 600 mg of elemental calcium can be efficiently absorbed in any single dose, with excess calcium passing unabsorbed through the gut.

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