Treatment FAQ

how long does testosterone treatment last

by Miss Kristina Sauer Published 2 years ago Updated 2 years ago
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Pellets may be injected two to three times per year. Injectable testosterone costs from $50 to $150 per 10 ml vial, which will last anywhere from four to five months. Bryan Cowing starting writing in 2002 for a local newspaper.

Full Answer

How long do you stay on testosterone replacement therapy?

The length of time that any single person needs to be on testosterone replacement therapy varies, based on your symptoms, age, sex and weight. Generally speaking, testosterone therapy is given over a course of a few months. Typically, for a first time prescription, you will be prescribed a 10 week or a 20 week program of testosterone therapy.

How long does it take testosterone to leave the body?

This indicates that complete elimination of exogenous testosterone (propionate) will likely take between 11 days and 16.5 days after your final dose. Compared to enanthate and cypionate, testosterone propionate is eliminated in a short-duration (within just 2 to 3 weeks).

How long before Testosterone starts to work?

When will testosterone injection start working? According to scientific studies, improvements in libido and spontaneous morning erections can occur within 3 weeks of starting TRT, while the benefits for erectile function may reach their maximum after 9 weeks or longer.

How long does Stromectol last in the body?

Ivermectin medication is metabolized in the liver and fecal excretion is greater than urinary excretion. Ivermectin tablets have a half life of approximately 18 hours while ivermectin cream has a half life of under 7 hours. Some providers will prescribe ivermectin 200 mcg / kg of body weight tablets or utilize ivermectin 3 mg tablets.

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Normal Testosterone Levels

Doctors diagnose age-related hypogonadism based on two factors: low testosterone levels and symptoms of low testosterone. Before we get into how long testosterone therapy lasts, let’s look at the recommended lab tests and the symptoms of low testosterone levels.

The Role of Testosterone

Testosterone is a hormone that is primarily produced in the testes. It helps maintain and support:

How Long Does Testosterone Theory Usually Take to See Results?

Though we cannot offer a definitive timeline, there has been enough research to map out a guide on when you might expect to see an improvement in your symptoms. Saad et al. developed the following timelines after reviewing available research in a meta-analysis.

Factors That Influence the Duration of Treatment

If your baseline testosterone level is low and you start testosterone therapy, you could be on it indefinitely. When the therapy is stopped, your testosterone level is expected to fall. When your testosterone levels fall below a certain level, your symptoms may return.

How to Get Your Testosterone Levels Tested

If your symptoms are consistent with low testosterone levels, the next step in regaining your health is to have your testosterone levels checked. Invigor Medical’s healthcare professionals specialize in men’s health and can help you determine whether testosterone therapy is right for you.

DISCLAIMER

While we strive to always provide accurate, current, and safe advice in all of our articles and guides, it’s important to stress that they are no substitute for medical advice from a doctor or healthcare provider. You should always consult a practicing professional who can diagnose your specific case.

Can you stay on testosterone therapy?

As TRT researchers know, it would be unrealistic to expect any form of hormone replacement therapy to have the same effect of every patient that uses it; and the individual efficacy of a person’s Low T therapy certainly has a bearing on how long can you stay on testosterone therapy. Some patients will receive exceptional results from their treatment and so they use it indefinitely; others may experience some benefits but not to same extent; and there will be some patients that simply don’t respond to treatment as desired after a reasonable period of using it, so they will be very likely to discontinue the program.

Does testosterone deficiency cause dramatic improvement?

As a general rule, patients with the greatest extent of testosterone deficiency before starting treatment tend to receive the most dramatic improvement in their symptoms , which are generally more severe than those exhibited by patients with a lesser degree of deficiency.

How long does testosterone propionate last?

Testosterone propionate lasts the shortest of ester compounds. The total lifespan persists a maximum of 72 hours. Testosterone, like other estrogen compounds, absorbs poorly and metabolizes quickly. Propionate leaves the system entirely by day 16.

When does testosterone drop off?

Drop-offs occur after the age of 20 and accelerate after 40. Worse, by 40 levels are half of what they were at 20. This is one of the reasons testosterone level testing has become important to men’s health in the last decade.

How often is BHRT performed?

BHRT hits less hard, as a process it is about steady function, not peak performance. Typically injections get performed every two weeks. This provides double the duration of the cypionate ester. BHRT also has the benefit of being indiscernible from natural testosterone production.

What are esters in testosterone?

Esters are the bonding chemicals that allow artificial testosterone to work with your system. Chemically, they form from OH (hydroxyls) and -O- (alkoxy groups). Then we’ll cover the differences between drop-off symptoms and withdrawal. So you’ll know what to expect when going through a replacement process.

How long does propionate take to drop off?

Injections need to be done daily to maintain levels and drop-offs occur in as little as 2 days after stopping. Propionate compounds are used by bodybuilders or athletes.

How long does enanthate stay in your system?

The duration lasts 4 days of peak and 10 days in total. You need to inject enanthate every 3 days, maximum, to maintain consistent levels. Enthanate compounds stay detectable in the system for 22 days.

How to find duration of BHRT?

To find the duration of a BHRT duration you need to test for a baseline hormone level and then for when that baseline returns. When undergoing BHRT as part of a hormone optimization plan, these levels get tested frequently in saliva or blood tartrate tests.

How long does it take for testosterone to go away?

Intramuscularly administered testosterone may take anywhere from 1 to 7 weeks to eliminate from your system. Cypionate usually remains in circulation for longer than enanthate and propionate formulations. Share a comment mentioning how long you believe testosterone stayed in your system after discontinuation.

How long does it take for testosterone cypionate to be removed from the body?

Knowing this, we can estimate that it’ll take around 44 days (6.29 weeks) to have fully eliminated exogenous testosterone cypionate from your system. Testosterone cypionate is known to stay in a user’s system for a considerably longer duration than enanthate and propionate esters.

How does age affect testosterone levels?

Dietary intake: It is understood that a testosterone user’s age can affect sex-hormone binding globulin (SHBG) levels , which in turn can influence how long testosterone stays in their system. In addition to age, dietary intake can also influence whether an individual exhibits high or low SHBG concentrations.

How long does testosterone enanthate stay in your system?

Testosterone cypionate: Reports document that the plasma elimination half-life of testosterone cypionate after intramuscular injection is around 8 days.

How long does it take for esters to be eliminated?

Intramuscularly administered esters will be eliminated from a user’s system in approximately 2 to 7 weeks after discontinuation. Upon cessation, a bulk of the testosterone dosage (90%) will be processed by the kidneys and excreted as conjugated glucuronides and/or sulfates within the urine.

Why do long term users accumulate testosterone esters?

This may be due to an attainment of steady state concentrations and increases in plasma levels of testosterone.

What is the role of testosterone in male development?

Testosterone is considered the defining sex hormone of males and is responsible for promoting reproductive tissue development (testis and prostate), along with sex-specific features such as: body hair, bone mass, and muscle development.

Is testosterone replacement therapy safe?

Medically Reviewed by Carol DerSarkissian, MD on August 07, 2019. If you've been diagnosed with an abnormally low T, testosterone replacement therapy (TRT) offers a lot of benefits. But there are risks, too.

Does TRT help with testosterone?

If you have an abnormally low T, boosting your testosterone levels with TRT can help bring your energy levels back to normal. It can also restore your sex drive. You may notice a drop in body fat and a buildup of muscle mass after TRT.

Does TRT help with ED?

If you have low testosterone, TRT may help restore your ability to have healthy erections and can boost your sex drive. But ED has many other possible causes. Low testosterone may not be the whole story behind your ED. Talk to your doctor to determine what's at the root of your erection problems.

How long does it take for testosterone to kick in?

These pills should kick in within a couple of days.

How often do you have to visit your doctor for TRT?

What happens is you have to visit your doctor either weekly or monthly for an injection, which is costly and time consuming, but there’s a much bigger problem at hand with TRT.

Is testosterone better than injections?

Testosterone pills are much better than injections because they are less expensive, less painful, and much more convenient. Those are the benefits, but the down side is that they still come with all of the same problems and side effects as injections come with.

Does testosterone increase penis size?

Nothing can physically increase the size of your penis, but really effective testosterone boosters can help improve erection quality, firmness, and blood flow. Technically it can not increase size, but it can help you get the absolute most out of what you have.

Do testosterone injections work?

What are the benefits of testosterone injections? The benefits are that injections work pretty quickly, and there’s a low chance the injection won’t work. However, the cons far outweigh the pros here. You have to deal with side effects, painful injections, inconvenience, and it costs a lot of money.

Does TRT work on foreign substances?

The body does not respond well to foreign substances, which is why TRT creates so many side effects. When you use testosterone gel, you apply it directly to the skin daily and the testosterone is absorbed through the skin.

Does testosterone make you angry?

Testosterone is not like anabolic steroids with regard to personality change. It does not make you angry or irritable like steroids do. The only personality change some people report is increased confidence as a result of being able to perform in the bedroom, looking better, and feeling better.

Why is testosterone injection used?

Testosterone injection is also used in women to treat certain types of breast cancer that have spread to other parts of the body. Testosterone should not be used to enhance athletic performance or to treat normal male aging. Testosterone injection is also used "off-label" for the treatment of gender dysphoria.

Why do men need testosterone injections?

Testosterone injection is used in men and boys to treat conditions caused by a lack of this hormone , such as delayed puberty or growth. It is only recommended for males with a known medical condition, such as a genetic disorder, problem with certain brain structures (called the hypothalamus and pituitary) or previous chemotherapy. ...

How do you know if you have excess testosterone?

Call your doctor at once if you notice any of these signs of excess testosterone: acne; changes in menstrual periods; male-pattern hair growth (such as on the chin or chest); hoarse or deepened voice; or. enlarged clitoris. Common testosterone side effects (in men or women) may include: breast swelling;

Can testosterone cause hives?

Testosterone side effects. Get emergency medical help if you have any signs of an allergic reaction to testosterone: hives ; difficult breathing; swelling of your face, lips, tongue, or throat. Get emergency medical help if you have any signs of a blood clot in the lung after using testosterone.

Is testosterone safe for pregnancy?

if you are pregnant or may become pregnant. To make sure testosterone is safe for you, tell your doctor if you have: heart disease or coronary artery disease; a history of heart attack, stroke, or blood clot; diabetes; enlarged prostate; high cholesterol or triglycerides (a type of fat in the blood);

What happens if you don't have enough testosterone?

If there’s not enough testosterone to go around, those androgen receptors all over your body and brain stay silent, leading to symptoms like low libido, weak erections and orgasms, inability to build muscle mass, low energy, or just feeling a little blue.

What is low testosterone?

A condition called hypogonadism —low testosterone—develops when your body can’t produce enough of it. That’s where testosterone replacement therapy—a treatment that raises your low testosterone levels—comes in. Testosterone can be supplemented in the form of an injection, a gel, a suction cup on your gums, and even a deodorant.

What hormones are produced when there is no testosterone in the blood?

Normally, when your pituitary gland senses that there's not enough testosterone in the bloodstream, it sends down a hormone called luteinizing hormone (LH) to signal your testicles to start producing more testosterone, and a hormone called follicle stimulating hormone (FSH) to signal sperm production.

Is testosterone replacement therapy dangerous?

Testosterone replacement therapy has traditionally come along with serious warning labels that your risk for heart attack, stroke, and prostate cancer could rise, but this is still very controversial—and recent evidence has begun to debunk some of these fears.

Does testosterone make you getty?

getty. In all men—whether you’re taking T or not—some testosterone is converted into the hormone estradiol, a form of estrogen. And in men who have more breast tissue by nature, the T they're taking that's naturally converted into estradiol could stimulate this breast tissue to grow.

Does testosterone cause fat loss?

While testosterone doesn’t directly incite fat loss itself, part of it may be thanks to the uptick in muscle mass—the more muscle you have, the higher your basal metabolic rate (or BMR) will be, which means your body will burn more calories at rest.

Is testosterone replacement bad for skin?

Morgentaler. Like other hormones, testosterone can increase oil production, which isn't necessarily a bad thing. It's important for healthy skin, so you may actually end up with a better complexion.

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Interactions

  • For individuals with truly insufficient testosterone production, testosterone replacement therapy (TRT) can increase levels within a normative range and improve health. However, in other cases, administration of exogenous testosterone may be conducted for athletic doping, bodybuilding, etc. and may trigger adverse reactions. To avoid failing a drug test and/or to avoid the adverse e…
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Symptoms

  • Assuming youve completely discontinued exogenous testosterone administration, you may gradually notice the emergence of testosterone withdrawal symptoms. These symptoms are typically a result of your body reverting back to homeostatic functioning without the exogenous testosterone boost that it had been receiving. In any regard, it is relatively difficult to pinpoint sp…
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Administration

  • Most individuals on testosterone replacement therapy (TRT) and/or using testosterone for the purposes of athletic doping will administer esters such as: testosterone propionate, testosterone enanthate, and testosterone cypionate. The most common route of administration is intramuscular (IM), meaning it is injected into muscle tissue. The below estimations of eliminati…
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Pharmacology

  • Testosterone propionate: Though the pharmacokinetics of testosterone propionate arent well elucidated, its elimination half-life is estimated between 2 and 3 days following intramuscular administration. This indicates that complete elimination of exogenous testosterone (propionate) will likely take between 11 days and 16.5 days after your final dos...
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Results

  • Testosterone cypionate: Reports document that the plasma elimination half-life of testosterone cypionate after intramuscular injection is around 8 days. This means that itll take slightly over a week to eliminate 50% of the exogenous testosterone from your system. Knowing this, we can estimate that itll take around 44 days (6.29 weeks) to have fully eliminated exogenous testoster…
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Pathophysiology

  • Age: An individuals age likely plays a role in how long exogenously administered testosterone stays in their system. Elderly individuals (over the age of 65) tend to exhibit altered concentrations of plasma proteins such as albumin and sex-hormone binding globulin (SHBG) compared to younger adults. As a result, it would be expected that the pharmacokinetics of testosterone woul…
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Causes

  • Dietary intake: It is understood that a testosterone users age can affect sex-hormone binding globulin (SHBG) levels, which in turn can influence how long testosterone stays in their system. In addition to age, dietary intake can also influence whether an individual exhibits high or low SHBG concentrations. The more protein you consume, the lower your SHBG levels are likely to be, wher…
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Mechanism

  • As SHBG concentrations decrease, unbound testosterone is thought to increase. Discrepancies in plasma concentrations of free testosterone may predict whether an individual is likely to eliminate testosterone quicker or slower than average. Someone with high SHBG may eliminate testosterone esters faster than those with low levels of SHBG due to the fact that plasma conce…
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Effects

  • The dosage of testosterone esters that you administer can affect how long it is likely to stay in your system. Since most individuals administer just enough to get their testosterone levels within the normal range, dosages injected are subject to significant variation. That said, the greater the dosage of testosterone you administer on a weekly or bi-weekly basis, the longer you can expec…
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Example

  • According to medical literature, an example of a therapeutic dose range for an ester like testosterone cypionate is 50 mg to 400 mg to be administered every 2 to 4 weeks. If you were to administer just 50 mg every 4 weeks, the exogenous testosterone would clear from your system quicker than if you were to take 400 mg every 4 weeks. This is due to the fact that higher dosage…
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Treatment

  • In addition to frequency of administration, it may be necessary to consider the term over which youve taken it. Someone thats been using testosterone esters for just a day is unlikely to retain them in systemic circulation for nearly as long as someone whos been using them for months. Long-term users are likely to exhibit heightened plasma concentrations of testosterone, as well …
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Side effects

  • High-frequency, long-term users are likely to accumulate testosterone esters within the kidneys to a greater extent than infrequent, short-term users. This may be due to an attainment of steady state concentrations and increases in plasma levels of testosterone. As a result of this accumulation, a reduction in excretion efficiency is likely among chronic long-term users of test…
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Diagnosis

  • There are several ways in which a person could be tested for testosterone. Though most individuals undergoing testosterone testing are simply doing so for medical purposes, others may be doing so to prove that they are clean or have refrained from doping in an athletic competition. The most common screening for testosterone doping among athletes is a urinary test, but other …
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Assessment

  • Urine is typically assessed for testosterone/epitestosterone (T/E) glucuronide ratio with various thresholds or cutoff values. This is accomplished with GC-MS (gas chromatography/mass spectrometry) and/or HPLC (high-performance liquid chromatography). As of 2005, the World Anti-Doping Agency (WADA) had T/E ratios set at 4. Should an individuals urine contain an abno…
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Risks

  • If youve recently stopped taking testosterone, you may be in a hurry to clear it from your system; especially if you utilized it for athletic doping. On the other hand, you may be concerned with health implications associated with exogenous testosterone. Below are some tips that may aid in the elimination of testosterone from your system. Should you consider any of these tips, always …
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