Afinitor is a long-term treatment. It should be taken every day as long as it is working unless unacceptable side effects occur. In clinical trials, the average duration of treatment was approximately 24.0 weeks (range one week to almost 200 weeks).
Full Answer
How effective is Afinitor for breast cancer?
User Reviews for Afinitor to treat Breast Cancer Afinitor has an average rating of 4.6 out of 10 from a total of 10 ratings for the treatment of Breast Cancer. 40% of users who reviewed this medication reported a positive effect, while 60% reported a negative effect.
Is Afinitor a long-term treatment?
Afinitor is a long-term treatment. It should be taken every day as long as it is working unless unacceptable side effects occur. In clinical trials, the average duration of treatment was approximately 24.0 weeks (range one week to almost 200 weeks). Afinitor (everolimus) is a targeted medicine that may be used to treat various cancers.
What is the prognosis of Afinitor for pancreatic neuroendocrine tumors?
A significant difference in progression-free survival was reported for Afinitor for pancreatic neuroendocrine tumors and neuroendocrine tumors of gastrointestinal or lung origin. Nguyen V. Afinitor.
What is the prognosis of Afinitor combined with exemestane?
There was no difference in overall survival rate in those assigned Afinitor combined with exemestane compared with those assigned placebo and exemestane after 39.3 months (just over 3 years).
How long can you stay on Afinitor?
Afinitor is usually taken every day for as long as it is working or until unacceptable side effects occur. It is meant to be taken as a long-term treatment. In clinical trials, the average duration of treatment was approximately 24.0 weeks (range one week to almost 200 weeks).
Can afinitor cure cancer?
Afinitor is a brand-name prescription medication that's used to treat certain types of cancers, tumors, and seizures. It contains the drug everolimus. Afinitor is a type of drug called a mammalian target of rapamycin (mTOR) inhibitor.
Can afinitor shrink tumors?
Just a handful of drugs have been approved by the U.S. FDA and one, Novartis's Afinitor (everolimus), deters cancer growth but doesn't shrink tumors, and it prolongs patient survival only a few months.
How long does remission last in breast cancer?
In all but stage IV breast cancer, efforts will be made to remove the tumor and use radiation and/or chemotherapy to get rid of all remaining cancer cells. To qualify as a complete or partial remission, the absence or reduction of cancer must last for at least one month.
What foods should you avoid with everolimus?
Do not drink or eat food for at least 1 hour after swishing and spitting the mouthwash. You should not eat grapefruit or drink grapefruit juice while you are taking this medicine. Grapefruit and grapefruit juice may cause higher levels of everolimus in the body. This could result in more unwanted effects.
Does Afinitor cause kidney failure?
Taking Afinitor can cause kidney problems, including kidney failure, in rare cases. You may be at higher risk of this side effect if you have preexisting kidney problems. Be sure to talk with your doctor before you start taking Afinitor.
How long does it take for a tumor to shrink?
At the same time, if a cell doesn't divide, it also cannot grow and spread. For tumors that divide slowly, the mass may shrink over a long, extended period after radiation stops. The median time for a prostate cancer to shrink is about 18 months (some quicker, some slower).
Does AFINITOR make you tired?
Examples of Afinitor's commonly reported side effects include: feeling tired or weak. diarrhea. mouth sores or swelling*
Can AFINITOR cause death?
Kidney Failure: Patients taking AFINITOR may develop kidney failure. In some people, this may be severe and can even lead to death.
How do you know if breast cancer is cured?
Cancer cells can still live in your body, even after treatment. In time, they may start to grow again. The doctor will let you know if you're in remission. It'll be based on your test results and how long it's been since you've had signs or symptoms of cancer.
What type of breast cancer is most likely to recur?
Cancer type: Aggressive cancers like inflammatory breast cancer and triple-negative breast cancer are harder to treat. They're more likely to come back and spread.
What percentage of breast cancer survivors have a recurrence?
According to the Susan G. Komen® organization, women with early breast cancer most often develop local recurrence within the first five years after treatment. On average, 7 percent to 11 percent of women with early breast cancer experience a local recurrence during this time.
Before Taking This Medicine
You should not use Afinitor if you are allergic to everolimus, sirolimus (Rapamune), or temsirolimus (Torisel).Tell your doctor if you have ever ha...
How Should I Take Afinitor?
Take Afinitor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction...
What Happens If I Miss A Dose?
Use the medicine as soon as you can, but skip the missed dose if you are more than 6 hours late for the dose. Do not use two doses at one time.
What Should I Avoid While Taking Afinitor?
Do not receive a "live" vaccine while using Afinitor, and avoid coming into contact with anyone who has recently received a live vaccine. There is...
What Other Drugs Will Affect Afinitor?
Tell your doctor about all your current medicines. Many drugs can interact with everolimus, especially: 1. an antibiotic or antifungal medicine; 2....
What is Afinitor?
Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 37,901 Afinitor users for its effectiveness, alternative drugs and more.
What is Breast cancer?
Breast cancer is found to be associated with 2,036 drugs and 1,329 conditions by eHealthMe.
How should I take Afinitor?
Take Afinitor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
What is Afinitor used for?
It is also used to treat certain types of advanced or progressive tumors of the stomach, intestines, or pancreas. Afinitor is also used to treat certain types of seizures or non-cancerous (benign) tumors of the brain or kidney in people with a genetic condition called tuberous sclerosis complex.
What other drugs will affect Afinitor?
Tell your doctor about all your current medicines. Many drugs can affect Afinitor, especially:
What is an avgiitor?
What is Afinitor? Afinitor ( everolimus) is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body. Afinitor is used to treat certain types of kidney cancer, breast cancer, or brain tumor.
What are the symptoms of allergic reactions to Afinitor?
Get emergency medical help if you have signs of an allergic reaction to Afinitor: hives; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have some of these symptoms if you also take an "ACE inhibitor" heart or blood pressure medication.
Can grapefruit be used with everolimus?
Grapefruit may interact with everolimus and lead to unwanted side effects. Avoid the use of grapefruit products. If you develop mouth sores or ulcers, avoid using mouthwashes or applying medicines that contain alcohol, peroxide, iodine, or thyme.
Can you take Afinitor with ACE inhibitor?
You may be more likely to have an allergic reaction if you take an "ACE inhibitor" heart or blood pressure medication while you are taking Afinitor. Tell your doctor about all your current medicines and any you start or stop using.
How long after Everolimus is it safe to breastfeed?
Breastfeeding. You’ll be advised not to breastfeed during treatment and for at least two weeks after your last dose of everolimus. This is because there is a chance your baby may absorb the drug through your breast milk, which might cause harm.
What is the treatment for cancer?
Everolimus is a targeted (biological) therapy . This group of drugs block the growth and spread of cancer. They target and interfere with processes in the cells that help cancer grow.
How often is Everolimus given?
Everolimus is given as a tablet once a day.
Can breast cancer make you feel lonely?
Being diagnosed with breast cancer can make you feel lonely and isolated.
Does breast cancer cause fatigue?
Cancer-related fatigue (extreme tiredness) Cancer-related fatigue is extreme tiredness that doesn’t go away with rest or sleep. It’s a very common side effect of breast cancer treatment and may affect you physically and emotionally.
Can you have a taste change with breast cancer?
If you do need to have dental treatment, talk with your oncologist about the best time to have this. Your taste can change, and some food may taste different, for example more salty, bitter or metallic. Our information on diet during breast cancer treatment includes tips on dealing with taste changes.
Is Everolimus given for breast cancer?
Everolimus may be offered to post-menopausal women with ER positive, HER2 negative , locally advanced or secondary breast cancer whose breast cancer has come back during or after taking the hormone therapy drugs letrozole or anastrozole. Everolimus is not currently given for primary breast cancer. 3.
What is Afinitor used for?
Afinitor (chemical name: everolimus) is a targeted therapy medicine approved by the U.S. Food and Drug Administration (FDA) to treat advanced-stage kidney cancer. Afinitor also is being studied as a treatment for other cancers, including breast cancer. In a study called BOLERO-2, women who received the hormonal therapy Aromasin ...
What is the difference between metastatic breast cancer and local breast cancer?
Locally advanced breast cancer is cancer that has spread beyond the breast to the chest wall below the breast or the skin on top of the breast. Metastatic breast cancer is cancer that has spread to parts of the body away from the breast, such as the bones or liver. All the women in the study had been treated with hormonal therapy ...
What is the oldest estrogen receptor modulator?
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What is the chemical name for Femara?
All the women in the study had been treated with hormonal therapy before participating in the study -- either Femara (chemical name: letrozole ) or Arimidex (chemical name: anastrazole) -- but the cancer had stopped responding to that treatment. About 66% of the women were randomly chosen to get Aromasin along with Afinitor.
How do kinases help cancer cells?
Kinases help all cells -- both healthy and cancer cells -- get the energy they need. When kinases don't act normally or are overactive they help certain breast cancers grow. mTOR inhibitors work by interfering with the mTOR kinase. Afinitor is a pill taken by mouth. 724 women diagnosed with advanced-stage or metastatic breast cancers ...
Does aromasin cause cancer?
Researchers found that the women who got Aromasin and Afinitor were, on average, less likely to have the cancer grow compared to women who got Aromasin and placebo. The time a woman lives without the cancer growing is called progression-free survival. The BOLERO-2 analysis presented in September 2011 showed that among women who got Aromasin ...