DIM is believed to be helpful in Breast Cancer treatment. Proponents claim that consuming it will help to increase the protection against multiple cancers, as well as promote Detoxification and weight loss. DIM acts as preventive care; it inhibits angiogenesis in cell culture models.
How much dim should a woman take?
Studies show the most effective amount of supplemental DIM is 30 mg. of absorbable DIM per dose, with daily doses of 60 mg. for women and 120 mg.
Can dim cause cancer?
The bottom line is that DIM may cause hormonal disturbances, reports NYU Langone Medical Center. DIM may lead to positive -- or negative -- effects on various types of hormone-sensitive cancers. For example, DIM has an anti-estrogenic effect, which may reduce the risk of developing thyroid cancer, according to a study in "Thyroid" in March 2011.
What does dim do to estrogen?
This is where DIM comes in. DIM can increase the ratio of “good” to “bad” estrogen. Regularly using it as a supplement promotes beneficial estrogen metabolism and helps restore a healthy hormonal balance. Since the benefits of DIM are directly linked to estrogen, you may think women can only take it.
What are the side effects of dim?
- Harmless change in color of urine (goes away after continued use)
- Headaches
- Joint pain/ache
- Dehydration
- Skin rash
Can breast cancer patients take DIM?
DIM has been intensely studied as a possible therapeutic agent in cancer treatment, especially for breast cancer. Studies report that DIM treatment promotes cellular growth arrest of cancer cells, as well as a decrease in mammary tumor formation in DMBA-treated rats [16, 24, 30].
How long does it take for DIM to work on estrogen?
It usually takes about 30 days for DIM supplements to start balancing estrogen. And it may take a few tries to get you on the best possible dosage. Questions still need to be answered, but the benefits of DIM supplements, when used under the supervision of a doctor, outweigh the common side effects.
Does DIM get rid of estrogen?
DIM supplements appear to help adjust the hormone estrogen. A few clinical trials have shown that it supports healthy estrogen levels, lowering the risk of certain cancers and diseases like lupus that are linked to estrogen.
How long before DIM starts to work?
People who use DIM supplement as a part of their weight loss program can realistically expect to see results within six weeks to six months.
Who should not take DIM?
Potential side effects and precautions Less common side effects include nausea, vomiting, diarrhea, and skin rash ( 3 ). As DIM supplements interact with estrogen levels, they may affect people with hormone-sensitive cancers or who are on hormone therapies.
Does DIM supplement make you gain weight?
DIM should not cause weight gain. Research has found that DIM increases lipolysis (fat burning), which suggests that DIM should not cause weight gain. It may even help you lose weight if the underlying cause of those excess pounds is estrogen-related.
Can DIM lower your estrogen too much?
This is where DIM enters the picture-DIM can successfully increase the ratio of “good” to “bad” estrogen. DIM supplementation specifically promotes beneficial estrogen metabolism and helps restore a healthy hormonal balance.
What is the best time to take DIM?
Most people find that taking DIM in the morning with a glass of water and a little food is the best way to go. Some women who have insomnia related to estrogen dominance, perimenopause, or menopause find that taking DIM at night helps them stay asleep longer – and even through the night.
What are the symptoms of low estrogen?
Signs of low estrogen include:Dry skin.Tender breasts.Weak or brittle bones.Trouble concentrating.Moodiness and irritability.Vaginal dryness or atrophy.Hot flashes and night sweats.Irregular periods or no periods (amenorrhea).More items...•
Does DIM work for weight loss?
Studies have found that DIM increases lipolysis (fat burning). This means it may be associated with weight loss and healthy weight management.
Does DIM interact with any medications?
Although there are no known drug interactions with DIM, the substance has shown considerable potential for interacting with many medications. For this reason, we recommend that if you use any medication that is critical for your health, do not use DIM except under a physician's supervision.
How long can you take DIM supplement?
A typical diet supplies 2-24 mg of diindolylmethane daily. It is possibly safe for most people when taken in doses up to 150 mg daily for up to 1 year. The most common side effects include headache, nausea, vomiting, gas, and diarrhea. Taking larger doses of diindolylmethane is possibly unsafe.
What is dim for cancer?
DIM FOR CANCER TREATMENT AND PREVENTION. Diindolylmethane, more commonly referred to as DIM, is a supplement you might not have heard of. Despite its lack of popularity, it is one of my favorite supplements due to its positive effects on hormones.
What is the body's DIM?
The body makes DIM from a substance called indole-3-carbinol (I3C), which is found in vegetables such as broccoli, cauliflower, cabbage, and Brussels sprouts. Once the body has converted I3C into DIM, the body has a very powerful anti-cancer substance at its disposal. One of DIM’s primary effects involves the hormone estrogen.
Which is better, DIM or I3C?
I feel strongly that DIM is the better supplement, because it has been shown to be more potent in protecting against cancers such as breast cancer. DIM is also a stronger antioxidant than I3C, to the point that it even has greater antioxidant activity than vitamin E.
Does dim increase estrogen?
The ratio of these two is very important, because too much of the 16 alpha-hydroxyestrone has been shown to increase the risk of the aforementioned cancers. DIM promotes estrogen being converted into 2-hydroxyestrone, rather than 16 alpha-hydroxyestrone, and thus lowers cancer risk.
Does DIM cause cancer?
One of DIM’s primary effects involves the hormone estrogen. As we know, estrogen is important for both men and women, but too much of it can predispose to various cancers. For women, too much estrogen increases the risk for breast, ovarian, and endometrial cancers. For men, too much estrogen is believed to contribute to prostate cancer.
Does DIM include prostate cancer?
In hormone-related cancers such as breast, ovaries, uterus, and prostate, I always include DIM in my protocols. I also include it in the protocols of those patients who have hormonal imbalance on lab testing, who have symptoms of hormonal imbalance, or who are interested in cancer prevention.
What is the compound DIM?
Diindolylmethane (DIM) is a metabolite of Indole-3-carbinol (I3C), a compound found in cruciferous vegetables including broccoli, cabbage, and cauliflower. It is the most studied of all I3C metabolites and is thought to be superior to IC3 as a chemoprotective compound for breast cancer and prostate cancer (3).
What is diindolylmethane?
Diindolylmethane is a compound found in cruciferous vegetables including broccoli, cabbage, and cauliflower. Laboratory studies suggest anti-inflammatory and anticancer effects, but data in humans are quite limited.
Does dim help with prostate cancer?
A few clinical studies suggest DIM may benefit patients with castration-resistant prostate cancer or help reverse abnormal cervical changes in cells . However, more studies are needed to determine safety and effectiveness, as DIM may affect the levels of certain hormones in the body. Purported Uses. Cancer prevention.
Benefits of using Diindolylmethane
Diindolylmethane (DIM) is supposed to bring about changes in the metabolism of estrogen, a biological process that is thought to influence the development of certain hormone-dependent cancers such as Breast Cancer. DIM is believed to be helpful in Breast Cancer treatment.
Side Effects
Sometimes the continuous consumption of Diindolylmethane supplements could aggravate hormonal conditions, including hormone-dependent cancers, endometriosis, and uterine fibroids.
Dosage
Scientific evidence is inadequate to determine a safe or effective dosage of Diindolylmethane or Diindolylmethane supplements. Health sources warn consumers that natural supplements are not always reliable, and dosage can significantly affect health.
What Should You Look For?
When the body digests indole-3-carbinol, a compound found in the following vegetables; Diindolylmethane is produced:
What is DIM cancer?
Cancer that begins in glandular (secretory) cells. Most cancers of the breast, pancreas, lung, prostate, and colon are adenocarcinomas. . [1] . DIM was found to have “lung cancer preventive effects” mediated via modulation of the receptor tyrosine kinase/PI3K/Akt-signaling pathway. [2] .
Does nutrition help with cancer?
Optimal nutrition can reduce the risks of developing cancer by up to 90%, hence it is a strong preventative tool for everyone. Cancer that begins in glandular (secretory) cells. Most cancers of the breast, pancreas, lung, prostate, and colon are adenocarcinomas. . [1] .
Is diindolylmethane good for cancer?
However, given its benefits to boost other natural therapies, it may be a good addition for all cancer patients.
Does dim work against cancer?
DIM demonstrated “exceptional anti-cancer effects against hormone responsive cancers like breast, prostate and ovarian cancers.”. [3] In a recent study, it was concluded that DIM rather than I3C was the active agent in cell culture studies destroying cancer. [4] Clinics that offer. Nutraceuticals.
Does DIM have isothiocyanates?
Individuals with genetic defects on Nrf2, Glutathione, and SOD genes have an even greater need to support such cellular garbage service. Also, DIM has shown synergistic benefits with isothiocyanates, and sulforaphane, the nutrients found in cruciferous vegetables that have been found to have such wonderful benefits for patients with cancer. [6] ...
Does dim help with cell cycle arrest?
DIM also was found to induce cell cycle arrest, helping slow replication of cancer cells. It also helps modulate key CYP enzymes in the liver, aiding important detoxification channels. DIM was found to alter angiogenesis, the lay-down of new vessels that cancers rely on for continued growth.
What Are DIM Supplements?
DIM is short for diindolylmethane, a metabolite of indole-3-carbinol. DIM is a compound that can only be made from cruciferous vegetables. When broccoli, cauliflower, and other cruciferous vegetables are exposed to stomach acid after chewing, indole-3-carbinol is created, which is then converted into DIM.
What Does DIM Do For Hormones?
One of the most significant things DIM may do for women is improve estrogen metabolism. Estrogen imbalance or excess estrogen, often called “estrogen dominance” can lead to a cascade of undesirable symptoms like hormonal headaches, breast tenderness, and PMS, to name a few.
Potential Benefits Of DIM Supplements
Studies on DIM have shown promise for breast health, acne, and reducing PMS. There is also data to support its benefits in certain cancers. DIM may be helpful for breast health because it supports Phase 1 metabolism of estrogen in the liver, favoring 2OHE1.
How Much DIM Do I Need?
Eating a diet rich in cruciferous vegetables may supply you with the DIM your body needs to support healthy estrogen metabolism. Remember that it requires you to chew well and have healthy hydrochloric acid levels present in the stomach. While a DIM supplement may be helpful for some women, it is not essential for everyone.
DIM Dosage
Typically, DIM supplements come in 50–300mg capsules. Starting with a lower dose of 50-100 mg is often best to avoid headaches, which can occur when you begin supplementing with DIM. Work with your doctor to determine whether DIM supplementation could be beneficial for you, and to determine the right dose for your body.
Food Sources Of DIM
Cruciferous vegetables contain Indole-3-Carbinol (I3C), which is converted to DIM by the body.
Drug Interactions With DIM
Diindolylmethane may help the liver work more efficiently, so if you’re on prescription medication that the liver is primarily responsible for breaking down, it’s possible that your medication may not stay in your system long enough to be effective.
What are the benefits of taking dim?
They’re also used to help prevent prostate enlargement, treat acne, aid weight loss, and reduce premenstrual syndrome (PMS) and menopause symptoms.
What is dim supplement?
Summary. DIM is a compound your body makes from cruciferous vegetables.
What is dim in nutrition?
DIM is a compound your body creates when you eat cruciferous vegetables. It’s also concentrated and sold as a supplement. As it affects estrogen levels, DIM may help treat a variety of conditions, including hormone-sensitive cancers and prostate issues.
What is diindolylmethane?
Diindolylmethane (DIM) is a compound created when you digest cruciferous vegetables, such as broccoli or Brussels sprouts ( 1. Trusted Source. , 2. Trusted Source. ). Research suggests that DIM affects estrogen levels in your body ( 1. Trusted Source. ). As a result, DIM supplements have been gaining popularity as a potential treatment ...
Does dim inhibit aromatase?
Additionally, DIM has been shown to inhibit an enzyme called aromatase, which converts testosterone to estrogen ( 1. Trusted Source. ). While cruciferous vegetables are the primary food source of DIM, you would need to eat several servings every day to reap this compound’s benefits ( 1. Trusted Source.
Is dim a toxic supplement?
Due to a lack of research in humans, little is known about the long-term safety and side effects of DIM supplements. Current human research doesn’t show DIM supplements to be toxic or have serious side effects. The most common side effects include darkening of the urine, an increase in bowel movements, headaches, and gas ( 3.
Does dim help with estrogen?
A 30-day study in 19 post-menopausal women with early-stage breast cancer found that taking 108 mg of DIM per day also resulted in beneficial changes in estrogen levels ( 9. Trusted Source. ). Test-tube and animal studies indicate that DIM protects against ovarian, prostate, and colon cancers as well.
Why is dim bad for cancer?
Research shows that about one in three cancer deaths is related to poor nutrition and could be prevented. Scientists see lower cancer risks in people who eat a lot of vegetables. That’s why DIM is so intriguing. The DIM compound may have several estrogen-related effects in your body:
What to do if you don't like dims?
If you don’t like them by themselves, include them in smoothies or baked dishes. You’ll also benefit from the other vitamins, minerals, and fiber they provide. Supplements may be more effective. One study found that DIM supplements are more effective than DIM that comes from food.
What vegetables are dim?
Researchers are looking into the anti-inflammatory and cancer-fighting effects of diindolylmethane (DIM), a compound commonly found in cruciferous vegetables including: Broccoli. Brussels sprouts.
Can you get dim from eating vegetables?
Even if you eat plenty of veggies, you may not get much DIM if cruciferous vegetables aren’t a regular part of your meals. Supplements can help. Here’s what to know: It’s not just for women. You may think of estrogen as only a female hormone, but it’s not. Men also benefit from DIM.
Is DIM safe for women?
Safety concerns. Though DIM supplements are popular , there is still no significant proof of their safety and effectiveness. In fact, they may be harm ful to some women. If you’re of reproductive age, estrogen is necessary to support healthy breast, bone, and endometrial tissue.
Is it safe to take dim while pregnant?
If you’re pregnant, your hormone levels are changing to support your growing baby. Altering those levels by taking DIM is dangerous for you both. DIM may also reduce the effectiveness of oral birth control medications. After menopause, women’s bodies make less estrogen.
Does DIM help with estrogen?
Cabbage. Cauliflower. DIM supplements appear to help adjust the hormone estrogen. A few clinical trials have shown that it supports healthy estrogen levels, lowering the risk of certain cancers and diseases like lupus that are linked to estrogen.
