Treatment FAQ

drug treatment to give a patient with gastric ulcer, and why

by Jace Fahey II Published 2 years ago Updated 1 year ago

Proton pump inhibitors — also called PPIs — reduce stomach acid by blocking the action of the parts of cells that produce acid. These drugs include the prescription and over-the-counter medications omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), esomeprazole (Nexium) and pantoprazole (Protonix).

Medication

  • Antacids neutralize gastric acid. ...
  • Histamine (H2) blockers reduce gastric acid by blocking the H2 receptors. ...
  • Proton pump inhibitors (PPIs) are drugs that block the three major pathways for acid production. ...
  • Medications to protect and strengthen the mucous lining of the stomach
  • Antibiotics to treat H. ...

Procedures

Ulcer medications

  • Proton pump inhibitors. The first-line medication for treating and preventing esophageal and peptic ulcers are proton pump inhibitors, such as pantoprazole, omeprazole, and esomeprazole.
  • H2 blockers. Normally, when a person eats, histamine is released into the stomach and signals stomach cells to secrete acid.
  • Other medications. ...

Nutrition

List Of 32 Foods Good For Stomach Ache And Stomach Ulcers Are Revealed

  1. Bananas. Why bananas are good for the stomach? ...
  2. Raw Food. According to advice from the experts, eating more raw foods instead of refined foods is the main solution in diet for people with digestive disorders, disorders of ...
  3. Apples. ...
  4. Toast. ...
  5. Soup. ...
  6. Herbal Teas. ...
  7. Coconut Juice. ...
  8. Ginger. ...
  9. Fennel. ...
  10. Yogurt. ...

More items...

What is the best treatment for gastric ulcer?

Ulcer treatment options

  • Drug discontinuation. Ulcers caused by drugs such as NSAIDs, anticoagulants, or corticosteroids will be treated by immediately discontinuing the drug along with medications to reduce stomach acid.
  • Antimicrobial agents. Ulcers caused by microbes will be treated by antimicrobial therapy along with medications to reduce stomach acid.
  • Medications. ...
  • Surgery. ...

What is the best over the counter medicine for ulcer?

What is the best diet for gastric ulcers?

What are the most common medications for ulcers?

Which drug is administered for patients with gastric ulcer?

Omeprazole, pantoprazole and lansoprazole are the PPIs most commonly used to treat stomach ulcers.

What are the drugs that ulcer patient can take?

Avoid Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). If you have an ulcer, use of NSAIDs, such as aspirin or ibuprofen could be dangerous and potentially life-threatening. A non-NSAID pain reliever, like acetaminophen, may be a safer choice.

Why is it that antibiotics are an effective treatment for stomach ulcers?

Treatments. Peptic ulcers caused by the bacteria Helicobacter pylori (H. pylori) are usually treated with a combination of antibiotics that kill the bacteria as well as other drugs to reduce stomach acid and protect the stomach lining.

Which of the following drugs are ulcer protective?

Antiulcer AgentsDexlansoprazole.Esomeprazole.Lansoprazole.Omeprazole.Pantoprazole.Rabeprazole.

What are the 3 drug classes used to treat peptic ulcers?

Peptic Ulcer Disease Treatment: MedicationAntacids neutralize gastric acid. ... Histamine (H2) blockers reduce gastric acid by blocking the H2 receptors. ... Proton pump inhibitors (PPIs) are drugs that block the three major pathways for acid production. ... Medications to protect and strengthen the mucous lining of the stomach.More items...

Why are multiple antibiotics given when a patient with and infected ulcer?

Use of more than one agent broadens the antibacterial spectrum of the empirical therapy and thus ensures that at least one agent will cover the infecting organism.

What antibiotics treat stomach ulcers?

Antibiotics are useful for ulcers caused by H. pylori bacteria....Examples of antibiotics for ulcers include:Amoxicillin (Amoxil)Clarithromycin (Biaxin)Metronidazole (Flagyl)Tinidazole (Tindamax)Tetracycline (Tetracycline HCL)Levofloxacin (Levaquin)

What is the first line treatment for peptic ulcer?

Vonoprazan (VPZ) with antibiotics is recommended as the first-line treatment for H. pylori eradication, and PPIs or VPZ with antibiotics is recommended as a second-line therapy. Patients who do not use NSAIDs and are H. pylori negative are considered to have idiopathic peptic ulcers.

What is the best treatment for stomach ulcers?

Proton pump inhibitors to block stomach acid production (such as esomeprazole, lansoprazole, omeprazole, or pantoprazole) Protectants that coat the ulcer and protect it against acid and enzymes, enhancing healing (like sucralfate) Bismuth (may help protect the lining and kill the bacteria). Rarely, surgery may be needed.

How long should I take antibiotics for stomach ulcers?

pylori (usually two or three different antibiotics are taken in combination for one to two weeks)

What causes a stomach ulcer?

Disruption of this balance can result in a break in this protective layer, causing a stomach ulcer. Disruptions may occur as a result of: 1 Excessive acid production 2 Excessive alcohol consumption (stimulates acid production) 3 Infection, particularly with a common stomach bacterium known as Helicobacter Pylori 4 Medications NSAIDs (eg, aspirin, ibuprofen, diclofenac, ketoprofen) 5 Other conditions, such as liver disease, Crohn’s disease, or Zollinger-Ellison syndrome 6 Physical stress, such as major surgery or burns.

Where do ulcers form?

They may also be called gastric ulcers. Ulcers can also form in your duodenum which is the first part of your small intestine, immediately beyond your stomach. A peptic ulcer is a term used to describe either a stomach or duodenal ulcer.

What to do if you have a lump in your stomach?

Your doctor will also conduct a physical examination, to check for bloating or lumps within your abdomen, and to listen for bowel sounds. Make sure you mention any areas of pain or tenderness.

Can Bismuth be used for ulcers?

Bismuth (may help protect the lining and kill the bacteria). Rarely, surgery may be needed. If NSAIDs have caused your stomach ulcer, your doctor may advise you to stop taking them, reduce their dosage, or switch to an alternative medicine. Follow his/her advice.

Does stress cause ulcers?

Although everyday stress (emotional stress) doesn’t appear to cause ulcers, it may make the pain worse. The risk of getting an ulcer is also increased in people who smoke and coffee has been known to stimulate acid production in the stomach and make ulcers worse.

What is the name of the medication that is used to treat GERD?

Prevacid (lansoprazole) Lansoprazole (Prevacid) is a moderately priced drug used to treat GERD, heartburn, gastric ulcer, and duodenal ulcer. It works by reducing acid in the stomach. It is slightly more popular than comparable drugs. It is available in generic and brand versions.

What is Nexium used for?

Nexium ( esomeprazole) is used to treat gastroesophageal reflux disease ( GERD ), ulcers, certain bacteria in the stomach, and inflammation of the esophagus. It can also be used to prevent ulcers in patients taking medicines called NSAIDs. Esomeprazole is more popular than other proton pump inhibitors.

What is esomeprazole used for?

It is used to treat gastroesophageal reflux disease ( GERD ), ulcers, certain bacteria in the stomach, and inflammation of the esophagus. It can also be used to prevent ulcers in patients taking medicines called NSAIDs.

What is Prilosec used for?

Prilosec (omeprazole) Omeprazole (Prilosec) is an inexpensive drug used to treat certain conditions where there is too much acid in the stomach, like ulcers and gastroesophageal reflux disease ( GERD ). It is more popular than comparable drugs.

Is omeprazole covered by Medicare?

This drug is slightly less popular than comparable drugs. It is available in brand and generic versions. It is not covered by most Medicare and insurance plans, but some manufacturer and pharmacy coupons can help offset the cost.

Is esomeprazole a prescription drug?

esomeprazole non-prescription. Drug class: Proton Pump Inhibitors. ESOMEPRAZOLE prevents the production of acid in the stomach. It is used to treat gastroesophageal reflux disease ( GERD ), ulcers, certain bacteria in the stomach, and inflammation of the esophagus.

What is the best treatment for a peptic ulcer?

Medications are used to reduce stomach acid to give the ulcer time to heal. Proton pump inhibitors (PPIs) are the drug of choice for peptic or esophageal ulcers, but H2 receptor blockers are also commonly prescribed.

What is the best medicine for esophageal ulcers?

In addition to drugs that reduce stomach acid, patients with esophageal or peptic ulcers will often take other medications to help relieve symptoms. Antacids, such as calcium carbonate, magnesium hydroxide, or bismuth subsalicylate, can be taken with meals to neutralize the acid in the stomach.

How long does it take for a stomach ulcer to heal?

A simple stomach ulcer without complications can take about one to two months to heal with the right medications. Duodenal ulcers can heal more quickly, typically within four to six weeks. An esophageal ulcer typically heals in two weeks to two months.

What is the first line of treatment for esophageal ulcers?

Proton pump inhibitors. The first-line medication for treating and preventing esophageal and peptic ulcers are proton pump inhibitors , such as pantoprazole, omeprazole, and esomeprazole. They are also the first-line treatment for GERD, the most common cause of esophageal ulcers.

How common is peptic ulcer disease?

Peptic ulcer disease is very common. Anywhere from 5% to 10% of the population will develop a peptic ulcer at some time during their lives. About 2% to 7% will experience an esophageal ulcer in their lifetime, mostly due to GERD.

Why do ulcers cause sores?

Peptic ulcers are due to an erosion of the defenses the stomach or intestinal tissues use to protect themselves against harmful stomach acid. When these defenses are compromised, the acid can eat away at the lining of the stomach or duodenum, causing sores.

How to heal a stomach ulcer?

An ulcer needs time to heal, so the best home remedies help guard the stomach against unnecessary irritation and work to lower stomach acid. Here are some examples: 1 Avoid foods that increase stomach acid such as dairy, coffee, and soft drinks 2 Avoid foods that irritate or damage the stomach such as alcohol, spicy foods, and fatty foods 3 Eat small meals throughout the day 4 Smoking also increases stomach acid, so stop smoking 5 Avoid NSAIDs (nonsteroidal anti-inflammatory drugs) for pain if you’re at risk of getting an ulcer. They reduce prostaglandins that protect the stomach lining from stomach acids. Use acetaminophen instead 6 Stress and nervousness may increase stomach acid, so manage stress with relaxation exercises, stretching, yoga, and other stress management techniques

What is the name of the drug that dissociates in stomach acid and forms a physical barrier over an inflam

Sucralfate. This drug is a sucrose-aluminum complex that dissociates in stomach acid and forms a physical barrier over an inflamed area, protecting it from acid, pepsin, and bile salts. It also inhibits pepsin-substrate interaction, stimulates mucosal prostaglandin production, and binds bile salts.

What is GERD in medical terms?

GERD = gastroesophageal reflux disease. Long-term proton pump inhibitor therapy produces elevated gastrin levels, which lead to enterochromaffin-like cell hyperplasia. However, there is no evidence of dysplasia or malignant transformation in patients receiving this treatment.

What are the components of H pylori eradication?

They promote ulcer healing and are also key components of H. pylori eradication regimens. Proton pump inhibitors have replaced H2 blockers in most clinical situations because of efficacy. Proton pump inhibitors include esomeprazole, lansoprazole, and panto prazole, these are available orally and IV, and omeprazole and rabeprazole, ...

What is the best way to reduce pepsin?

Antacids. These agents neutralize gastric acid and reduce pepsin activity (which diminishes as gastric pH rises to > 4.0). In addition, some antacids adsorb pepsin. Antacids may interfere with the absorption of other drugs (eg, tetracycline, digoxin, iron).

Is aluminum hydroxide a good antacid?

Nonabsorbable antacids (eg, aluminum or magnesium hydroxide) have fewer systemic adverse effects and are preferred. Aluminum hydroxide is a relatively safe, commonly used antacid. With chronic use, phosphate depletion occasionally develops as a result of binding of phosphate by aluminum in the gastrointestinal tract.

Is omeprazole the same as lansoprazole?

Oral and IV doses are the same. Omeprazole, esomeprazole, and lansoprazole are available without a prescription in the US. For uncomplicated duodenal ulcers, omeprazole 20 mg once a day or lansoprazole 30 mg once a day is given for 4 weeks.

Does cipridine interfere with P-450?

Cimetidine and, to a lesser extent, other H2 blockers interact with the P-450 microsomal enzyme system and may delay metabolism of other drugs eliminated through this system (eg, phenytoin, warfarin, theophylline, diazepam, lidocaine ).

Do antacids reduce pepsin?

In addition, some antacids adsorb pepsin. Antacids may interfere with the absorption of other drugs (eg, tetracycline, digoxin, iron).

Does sucralfate affect gastric acid?

It also inhibits pepsin-substrate interaction, stimulates mucosal prostaglandin production, and binds bile salts. It has no effect on acid output or gastrin secretion. Sucralfate seems to have trophic effects on the ulcerated mucosa, possibly by binding growth factors and concentrating them at an ulcer site. Systemic absorption of sucralfate is negligible. Constipation occurs in 3 to 5% of patients. Sucralfate may bind to other drugs and interfere with their absorption.

What is the test for ulcers in the upper digestive tract?

Tests may be done to look for ulcers in the inside of the upper digestive tract. These include: Upper GI series: Patients drink a substance called barium and a series of X-rays are taken. The barium helps the internal organs show up on imaging.

What is a peptic ulcer?

Priyanka Chugh, MD. on March 14, 2021. A peptic ulcer is the term used for a sore that occurs in the mucosal lining of the stomach, small intestine, or esophagus. When the ulcer is in the stomach it might also be called a gastric ulcer. Ulcers in the first part of the small intestine ( duodenum) may be called a duodenal ulcer.

What is the purpose of mucosal protective agents?

Mucosal protective agents (MPAs), which work to keep the body producing the beneficial mucosal layer in the stomach 2. The larger problem for people experiencing peptic ulcer disease as a result of therapy with NSAIDs is how to manage pain when those medications are discontinued.

What is the name of the bacteria that causes ulcers in the small intestine?

The most common cause of a peptic ulcer is a type of bacteria called Helicobacter pylori (H. pylori). A second, less common cause of peptic ulcers that's steadily increasing in importance is the use of non-steroidal anti-inflammatory medications (NSAIDs) ...

How do NSAIDs affect the stomach?

NSAIDs slow the production of protective mucus in the stomach and change its structure. A class of lipids made by the body called prostaglandins have an effect on pain receptors. NSAIDs work to reduce pain by blocking the enzymes that are involved in the production of certain prostaglandins.

What is the function of NSAIDs in the stomach?

Blood circulation that aids in the repair and renewal of cells in the stomach’s mucosal layer. NSAIDs slow the production of protective mucus in the stomach and change its structure.

What is the protective layer of the stomach?

Prostaglandins are also protective in the mucosal layer of the stomach, and when they are depleted, there can be a break in that layer. The suppression of the body's natural defenses against gastric acids can lead to inflammation in the stomach lining.

Examples

Combination drug therapy regimens commonly used to treat an H. pylori infection include the following options:

How It Works

The right antibiotics combinations usually kill Helicobacter pylori ( H. pylori) bacteria that are the cause of many peptic ulcers. At least two antibiotics are used, because combination treatment works better and is less likely to fail because of resistance to the antibiotics.

Why It Is Used

Combination drug therapy that includes at least two antibiotics, an acid reducer, and sometimes a bismuth compound is recommended for people who have peptic ulcer disease and are known to be infected with Helicobacter pylori ( H. pylori ).

How Well It Works

Helicobacter pylori ( H. pylori) infections are cured 70% to 85% of the time when the right combination drug treatment is used.

Side Effects

All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.

What To Think About

It is very important that you take all of the medicine prescribed. Do not stop taking your medicine even if you feel better. It may seem like a lot of pills to take, but it is also important to take a regimen that contains at least three medicines to cure Helicobacter pylori ( H. pylori ).

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