Medication
Mayo Clinic Cancer Center is one of a handful of U.S. facilities that received a National Cancer Institute Specialized Program of Research Excellence (SPORE) grant for lymphoma research. Mayo applies that research to developing more effective and less toxic treatments for all forms of lymphoma.
Procedures
Many types of non-Hodgkin's lymphoma exist, including rare forms that some doctors may have never seen. Research shows that having your tissue samples reviewed by an experienced doctor may result in a more accurate diagnosis. If you have any concerns about your diagnosis, consider seeking a second opinion.
Therapy
Keeping your close relationships strong will help you deal with your non-Hodgkin's lymphoma. Friends and family can provide the practical support you'll need, such as helping take care of your house if you're in the hospital. And they can serve as emotional support when you feel overwhelmed by cancer.
Self-care
For certain types of non-Hodgkin's lymphoma, radiation therapy may be the only treatment you need, particularly if your lymphoma is slow growing and located in just one or two spots. More commonly, radiation is used after chemotherapy to kill any lymphoma cells that might remain.
Nutrition
What is Mayo Clinic doing for Lymphoma Research?
Should I seek a second opinion about my non-Hodgkin's lymphoma diagnosis?
How can I deal with non-Hodgkin's lymphoma?
Is radiation therapy the only treatment for non-Hodgkin lymphoma?
What is the best hospital for non-Hodgkin's lymphoma?
Mayo Clinic doctors are widely respected for their expertise in diagnosing and treating people with all types of non-Hodgkin's lymphoma, including the rare and aggressive. Each year Mayo Clinic doctors care for more than 6,900 people with non-Hodgkin's lymphoma.
Where does non-Hodgkin's lymphoma usually spread?
Non-Hodgkin's lymphoma generally involves the presence of cancerous lymphocytes in your lymph nodes. But the disease can also spread to other parts of your lymphatic system. These include the lymphatic vessels, tonsils, adenoids, spleen, thymus and bone marrow.
What is the recurrence rate for non-Hodgkin's lymphoma?
Abstract. Complete remission can be achieved in 60-80% of adults with diffuse aggressive non-Hodgkin's lymphoma. However, 20-40% of them will subsequently relapse.
Are you ever cured of non-Hodgkin's lymphoma?
Yes, NHL is a very treatable disease and curable in many cases, particularly with aggressive NHL. Before treatment begins, it is necessary to know how far the cancer has advanced. This is called the stage of the disease.
Which is worse Hodgkin's lymphoma or non-Hodgkin's lymphoma?
The prognosis of Hodgkin's lymphoma is also better than that of non-Hodgkin's lymphoma since non-Hodgkin's lymphoma is often diagnosed at a more advanced stage. Both forms of blood cancer are treatable when caught early, however.
What is the life expectancy of someone with non-Hodgkin's lymphoma?
The overall 5-year relative survival rate for people with NHL is 73%. But it's important to keep in mind that survival rates can vary widely for different types and stages of lymphoma....Follicular lymphoma.SEER Stage5-Year Relative Survival RateLocalized97%Regional91%Distant86%All SEER stages combined90%Mar 2, 2022
Can you live a long life after non-Hodgkin lymphoma?
Takeaway. The outlook for people with non-Hodgkin's lymphoma isn't generally as good as that of Hodgkin's lymphoma, but it still has a better outlook than many other cancers. More than 70 percent of people live longer than 5 years after their diagnosis.
What are symptoms of non-Hodgkin's lymphoma returning?
Signs of a lymphoma relapse include:Swollen lymph nodes in your neck, under your arms, or in your groin.Fever.Night sweats.Tiredness.Weight loss without trying.
Is non-Hodgkin's lymphoma a death sentence?
What is the survival rate for non-Hodgkin lymphoma? According to the American Cancer Society, about 71 percent of people of all races with non-Hodgkin lymphoma are still alive five years after diagnosis. Children tend to fare better, with 87 percent living for at least five years after diagnosis.
Can you go into remission with non-Hodgkin's lymphoma?
Hodgkin lymphoma and high-grade non-Hodgkin lymphoma often goes into complete remission and needs no further treatment. However, some people relapse and need more treatment.
Which has better survival rate Hodgkin's or non-Hodgkin lymphoma?
More than 86 percent of patients diagnosed with Hodgkin lymphoma survive five years or more. About 70 percent of patients diagnosed with non-Hodgkin lymphoma survive five years or more. There are six varieties of Hodgkin lymphoma.
How fast does non-Hodgkin's lymphoma spread?
After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms. This type progresses fairly rapidly without treatment.
What is the Mayo Clinic?
Mayo Clinic offers services for people who have completed non-Hodgkin's lymphoma treatment through cancer survivorship clinics. Follow-up medical care is important for every person who was treated for non-Hodgkin's lymphoma. The survivorship clinic offers evaluation for physical and psychological side effects, as well as provides plans for follow-up care and healthy living after cancer treatment. Sometimes follow-up care involves blood tests or bone marrow tests.
What is a Mayo Clinic hematopathologist?
Mayo Clinic pathologists who specialize in diseases of the blood (hematopathologists) are experienced in accurately diagnosing and staging all the subtypes of non-Hodgkin's lymphoma, including very rare ones. Some types can be distinguished from each other only by advanced laboratory testing.
What kind of doctor is involved in cancer treatment?
Surgeons. Dermatologists. If you have other health conditions that could be affected by cancer treatment, your team may include other specialists. Your team works together to provide exactly the care you need.
Does Mayo Clinic require a referral?
In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care.
Is Mayo Clinic a national cancer center?
Mayo Clinic Cancer Center meets the strict standards for a National Cancer Institute comprehensive cancer center, which recognize scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment.
Does Mayo Clinic have lymphoma?
And because Mayo Clinic is a leader in lymphoma research, you may also have access to the latest treatments by way of clinical research studies (clinical trials).
What is non-Hodgkin lymphoma?
Non-Hodgkin's lymphoma is a type of cancer that begins in your lymphatic system, which is part of the body's germ-fighting immune system. In non-Hodgkin's lymphoma, white blood cells called lymphocytes grow abnormally and can form growths (tumors) throughout the body. Non-Hodgkin's lymphoma is a general category of lymphoma.
What is the lymphatic system?
Your body's lymphatic system is part of your immune system, which protects you against infection and disease. The lymphatic system includes your spleen, thymus, lymph nodes and lymph channels, as well as your tonsils and adenoids.
What type of lymphoma starts with B cells?
Non-Hodgkin's lymphoma most often begins in the: 1 B cells. B cells are a type of lymphocyte that fights infection by producing antibodies to neutralize foreign invaders. Most non-Hodgkin's lymphoma arises from B cells. Subtypes of non-Hodgkin's lymphoma that involve B cells include diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma and Burkitt lymphoma. 2 T cells. T cells are a type of lymphocyte that's involved in killing foreign invaders directly. Non-Hodgkin's lymphoma occurs much less often in T cells. Subtypes of non-Hodgkin's lymphoma that involve T cells include peripheral T-cell lymphoma and cutaneous T-cell lymphoma.
What is the most common type of lymphoma?
Diffuse large B-cell lymphoma and follicular lymphoma are among the most common subtypes. The other general category of lymphoma is Hodgkin's lymphoma. Advances in diagnosis and treatment of non-Hodgkin's lymphoma have helped improve the prognosis for people with this disease.
What type of lymphocyte fights infection?
B cells are a type of lymphocyte that fights infection by producing antibodies to neutralize foreign invaders. Most non-Hodgkin's lymphoma arises from B cells. Subtypes of non-Hodgkin's lymphoma that involve B cells include diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma and Burkitt lymphoma.
Where are lymph nodes in the neck?
One of the most common places to find swollen lymph nodes is in the neck. The inset shows three swollen lymph nodes below the lower jaw. Signs and symptoms of non-Hodgkin's lymphoma may include: Swollen lymph nodes in your neck, armpits or groin. Abdominal pain or swelling.
Does non-Hodgkin's lymphoma occur in T cells?
Non-Hodgkin's lymphoma occurs much less often in T cells. Subtypes of non-Hodgkin's lymphoma that involve T cells include peripheral T-cell lymphoma and cutaneous T-cell lymphoma. Whether your non-Hodgkin's lymphoma arises from your B cells or T cells helps to determine your treatment options.
What is Mayo Clinic?
Mayo Clinic Cancer Center is one of a handful of facilities that received a U.S. National Cancer Institute Specialized Program of Research Excellence (SPORE) grant for lymphoma research. Mayo applies that research to developing more effective and less toxic treatments for all forms of lymphoma.
Where is Mayo Clinic located?
Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.
Is Mayo Clinic a non-Hodgkin's lymphoma center?
Mayo Clinic is an international leader in non-Hodgkin's lymphoma research. The Hematologic Malignancies Program conducts blood and bone marrow cancer research in coordination with the Mayo Clinic Cancer Center. The Mayo Clinic Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center — ...
What is the treatment for lymphoma?
Treatments offered to people with lymphoma include bone marrow transplant, chemotherapy, radiation therapy, targeted therapy, immunotherapy and CAR-T cell therapy, among others. And because Mayo Clinic is a leader in lymphoma research, you also have access to the latest treatments by way of clinical research studies (clinical trials).
Who is the Mayo Clinic hematopathologist?
Mayo Clinic pathologists who specialize in diseases of the blood (hematopathologists) are experienced with all types of lymphomas. They work closely with your care team to ensure an accurate diagnosis of this complex disease, which has many variations and rare forms. Research shows that expert review by pathologists who see many lymphoma cases is key to developing an appropriate treatment plan.
How many people do Mayo Clinic hematologists treat?
Each year Mayo Clinic doctors care for more than 7,600 people with lymphoma.
What is early cancer therapy?
The Early Cancer Therapeutics Group at Mayo Clinic offers people whose cancers haven't responded to standard chemotherapy or other treatments the opportunity to join an early-phase clinical trial of a potential new treatment.
Is Mayo Clinic a SPORE?
Mayo Clinic is one of a select group of medical centers in the United States to be recognized as a Specialized Program of Research Excellence (SPORE) for lymphoma , funded by the National Cancer Institute.
Does Mayo Clinic require a referral?
In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care.
Does Mayo Clinic have lymphoma?
Mayo Clinic offers services for people who have completed lymphoma treatment through cancer survivor ship clinics. Follow-up medical care is important. The lymphoma survivorship clinic offers evaluation for physical and psychological side effects, as well as provides plans for follow-up care and healthy living after cancer treatment. Sometimes follow-up care involves blood tests or imaging studies.
Mayo Clinic recommends new routine testing for some non-Hodgkin lymphomas
Three recently discovered subgroups could change treatment recommendations.
Summary
Three recently discovered subgroups could change treatment recommendations.
Target Audience
The target audience for Mayo Clinic Proceedings is primarily internal medicine physicians and other clinicians who wish to advance their current knowledge of clinical medicine and who wish to stay abreast of advances in medical research.
Learning Objectives
On completion of this article, you should be able to (1) identify risk factors associated with non-Hodgkin lymphoma; (2) define prognostic factors that are associated with patient outcome; and (3) determine the standard treatment approaches for lymphoma patients.
Mayo Clinic Case-Control Study of Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia
The Lymphoma Epidemiology Lab's case-control study tests hypotheses about the etiology of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.
Study protocol
Participants enrolled in the study were newly diagnosed patients with Hodgkin's lymphoma or non-Hodgkin's lymphoma, including chronic lymphocytic leukemia, from Minnesota, Iowa and Wisconsin seen at Mayo Clinic's campus in Rochester, Minnesota, from Sept. 1, 2002, to Dec. 31, 2013.
Study outcomes
Although the study is no longer recruiting participants, data analysis is ongoing.
Diagnosis
Treatment
Clinical Trials
Coping and Support
Specialist to consult
Preparing For Your Appointment
Lymphoma Care at Mayo Clinic
- Several non-Hodgkin's lymphoma treatments are available. Which treatment or combination of treatments is best for you will depend on the particulars of your lymphoma, such as the types of cells involved and whether your lymphoma is aggressive. Your doctor also considers your overall health and your preferences. If your lymphoma appears to be slow growing (indolent) and doesn'…
The Mayo Clinic Experience and Patient Stories
- Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
Expertise and Rankings
- A non-Hodgkin's lymphoma diagnosis can be overwhelming. The following strategies and resources may help you deal with cancer: 1. Learn about non-Hodgkin's lymphoma.Learn enough about your cancer to feel comfortable making decisions about your treatment and care. In addition to talking with your doctor, look for information in your local library and on the internet. …
Locations, Travel and Lodging
- Make an appointment with your family doctor if you have any signs or symptoms that worry you. If your doctor suspects you have a type of lymphoma, he or she may refer you to a doctor who specializes in diseases that affect blood cells (hematologist). Because appointments can be brief, and because there's often a lot of information to discuss, it's a good idea to be well prepared. He…
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