Precautions
· Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain. Back pain, belly pain, or blood in the urine. May be signs of a kidney stone. Seizures . A very bad and sometimes deadly type of anemia called hemolytic anemia has happened with ceftriaxone.
How should I take ceftriaxone?
· Monitor prothrombin time during Ceftriaxone treatment in patients with impaired vitamin K synthesis or low vitamin K stores (e.g., chronic hepatic disease and malnutrition). Vitamin K administration (10 mg weekly) may be necessary if the prothrombin time is prolonged before or during therapy.
What should I avoid mixing with ceftriaxone?
Undernourished condition—May be worsened by ceftriaxone and you may need to take Vitamin K. Proper Use A nurse or other trained health professional will give you this medicine. This …
How should I store ceftriaxone?
Ceftriaxone injection is in a class of medications called cephalosporin antibiotics. It works by killing bacteria. Antibiotics such as ceftriaxone injection will not work for colds, flu, or other …
What is the pharmacology of ceftriaxone?
· Drink plenty of liquids to keep your kidneys working properly while using ceftriaxone. Use this medicine for the full prescribed length of time, even if your symptoms …
What Do I Need to Tell My Doctor Before I Take Ceftriaxone?
For all patients taking ceftriaxone: 1. If you have an allergy to ceftriaxone or any other part of ceftriaxone. 2. If you are allergic to any drugs...
What Are Some Things I Need to Know Or Do While I Take Ceftriaxone?
1. Tell all of your health care providers that you take ceftriaxone. This includes your doctors, nurses, pharmacists, and dentists. 2. Very bad and...
How Is This Medicine (Ceftriaxone) Best Taken?
Use ceftriaxone as ordered by your doctor. Read all information given to you. Follow all instructions closely. 1. It is given as a shot into a musc...
What Are Some Side Effects That I Need to Call My Doctor About Right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...
What Are Some Other Side Effects of Ceftriaxone?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...
How Do I Store and/or Throw Out Ceftriaxone?
1. If you need to store ceftriaxone at home, talk with your doctor, nurse, or pharmacist about how to store it.
Who to talk to about ceftriaxone?
Check with your pharmacist. If you have any questions about ceftriaxone, please talk with your doctor, nurse, pharmacist, or other health care provider.
What to do if your symptoms don't get better?
If your symptoms or health problems do not get better or if they become worse, call your doctor.
What to do if you think you have an overdose?
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Can ceftriaxone cause anemia?
A very bad and sometimes deadly type of anemia called hemolytic anemia has happened with ceftriaxone. Call your doctor right away if you have pale skin, dizziness, fever or chills, very bad back or belly pain, dark urine, yellow skin or eyes, or you feel very tired or weak.
Does ceftriaxone affect lab results?
This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take ceftriaxone.
Can you get CDAD after taking antibiotics?
CDAD may happen during or a few months after taking antibiotics. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools. Check with your doctor before treating diarrhea. Ceftriaxone side effects (more detail)
Can C diff cause diarrhea?
Rarely, a severe form called C diff–associated diarrhea ( CDAD) may happen. Sometimes, this has led to a deadly bowel problem ( colitis ). CDAD may happen during or a few months after taking antibiotics. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools.
What should be done before instituting treatment with Ceftriaxone for injection?
Before instituting treatment with Ceftriaxone for Injection, USP, appropriate specimens should be obtained for isolation of the causative organism and for determination of its susceptibility to the drug. Therapy may be instituted prior to obtaining results of susceptibility testing.
Why is ceftriaxone used for injection?
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for injection and other antibacterial drugs, Ceftriaxone for injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Does Ceftriaxone cause diarrhea?
Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including Ceftriaxone, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile.
Can you give ceftriaxone to a patient with hypersensitivity?
Before therapy with Ceftriaxone is instituted, careful inquiry should be made to determine whether the patient has had previous hypersensitivity reactions to cephalosporins, penicillins and other beta-lactam agents or other drugs. This product should be given cautiously to penicillin and other beta-lactam agent‑sensitive patients. Antibacterial drugs should be administered with caution to any patient who has demonstrated some form of allergy, particularly to drugs. Serious acute hypersensitivity reactions may require the use of subcutaneous epinephrine and other emergency measures.
Is lidocaine a contraindication for Ceftriaxone?
Intravenous administration of Ceftriaxone solutions containing lido caine is contraindicated. When lidocaine solution is used as a solvent with Ceftriaxone for intramuscular injection, exclude all contraindications to lidocaine. Refer to the prescribing information of lidocaine.
Is ceftriaxone contraindicated?
Ceftriaxone is contraindicated in patients with known hypersensitivity to Ceftriaxone, any of its excipients or to any other cephalosporin. Patients with previous hypersensitivity reactions to penicillin and other beta lactam antibacterial agents may be at greater risk of hypersensitivity to Ceftriaxone (see WARNINGS – Hypersensitivity ).
Does Ceftriaxone help with post operative infections?
The preoperative administration of a single 1 gm dose of Ceftriaxone for Injection, USP may reduce the incidence of postoperative infections in patients undergoing surgical procedures classified as contaminated or potentially contaminated (e.g., vaginal or abdominal hysterectomy or cholecystectomy for chronic calculous cholecystitis in high-risk patients, such as those over 70 years of age, with acute cholecystitis not requiring therapeutic antimicrobials, obstructive jaundice or common duct bile stones) and in surgical patients for whom infection at the operative site would present serious risk (e.g., during coronary artery bypass surgery). Although Ceftriaxone for Injection, USP has been shown to have been as effective as cefazolin in the prevention of infection following coronary artery bypass surgery, no placebo-controlled trials have been conducted to evaluate any cephalosporin antibiotic in the prevention of infection following coronary artery bypass surgery.
How often can you give ceftriaxone?
It is sometimes given as a single dose and sometimes given once or twice a day for 4-14 days, depending on the type of infection being treated. You may receive ceftriaxone injection in a hospital or doctor's office, or you may administer the medication at home.
Why is ceftriaxone given before surgery?
Ceftriaxone injection is also sometimes given before certain types of surgery to prevent infections that may develop after the operation. Ceftriaxone injection is in a class of medications called cephalosporin antibiotics. It works by killing bacteria. Antibiotics such as ceftriaxone injection will not work for colds, flu, ...
Does ceftriaxone cause shortness of breath?
Ceftriaxone injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: pain, tenderness, hardness, or warmth in the place where ceftriaxone was injected. pale skin, weakness, or shortness of breath when exercising. diarrhea.
Can you continue your normal diet?
Unless your doctor tells you otherwise, continue your normal diet.
Can you get pregnant while taking ceftriaxone?
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using ceftriaxone injection, call your doctor.
Can you give a baby ceftriaxone?
tell your doctor if your child was born prematurely or is younger than 4 weeks of age. Your doctor may not want your baby to receive ceftriaxone injection .
Can you take more than one ceftriaxone shot?
If you will be using more than one dose of ceftriaxone injection, use the medication until you finish the prescription, even if you feel better. If you stop using ceftriaxone injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
How to keep kidneys working while taking ceftriaxone?
Drink plenty of liquids to keep your kidneys working properly while using ceftriaxone. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication.
Where is ceftriaxone injected?
Ceftriaxone is injected into a muscle or as an infusion into a vein (IV). A healthcare provider will give you this injection when ceftriaxone is used to prevent infection from surgery. You may be shown how to use the injection at home to treat an infection.
What other medications can affect ceftriaxone?
Tell your doctor about all your other medicines, especially: fluconazole; vancomycin; or. other injected (IV) antibiotics. This list is not complete. Other drugs may affect ceftriaxone, including prescription and over-the-counter medicines, vitamins, and herbal products.
Does Ceftriaxone cause hives?
Ceftriaxone side effects. Get emergency medical help if you have signs of an allergic reaction ( hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Can you take ceftriaxone with a cold?
Ceftriaxone will not treat a viral infection such as the flu or a common cold. Ceftriaxone can affect the results of certain medical tests. Tell any doctor who treats you that you are using ceftriaxone. After mixing ceftriaxone with a diluent, you must use the medicine within a certain number of hours or days.
Can you mix ceftriaxone with a liquid?
You may need to mix ceftriaxone with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine. Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it.
Can you give a baby ceftriaxone?
Do not use ceftriaxone in a child without a doctor's advice, and never give more than the child's prescribed dose. Ceftriaxone injection could be dangerous when given to a newborn baby with any intravenous medicines that contain calcium, including total parental nutrition (TPN).
How often should I take gentamicin for endocarditis?
American Heart Association (AHA) and IDSA Recommendations:#N#-Native valve infective endocarditis (NVE) due to highly penicillin-susceptible viridans group streptococci (VGS) or S gallolyticus (bovis): 2 g IV or IM every 24 hours for 4 weeks#N#---When used with gentamicin: 2 g IV or IM every 24 hours for 2 weeks#N#-Prosthetic valve (or other prosthetic material) infection due to VGS or S gallolyticus (bovis): 2 g IV or IM every 24 hours for 6 weeks#N#-NVE or prosthetic valve (or other prosthetic material) infection due to Enterococcus species by a strain susceptible to penicillin and gentamicin (if able to tolerate beta-lactam therapy): 2 g IV every 12 hours for 6 weeks#N#-NVE or prosthetic valve (or other prosthetic material) infection due to Enterococcus species by a strain susceptible to penicillin and resistant to aminoglycosides or streptomycin-susceptible gentamicin-resistant (if able to tolerate beta-lactam therapy): 2 g IV every 12 hours for 6 weeks#N#-NVE or prosthetic valve (or other prosthetic material) infection due to HACEK microorganisms: 2 g IV or IM every 24 hours#N#---Duration of therapy: 4 weeks (NVE); 6 weeks (prosthetic valve infection)#N#US CDC Recommendations:#N#-Gonococcal endocarditis: 1 to 2 g IV every 12 to 24 hours for at least 4 weeks#N#Comments:#N#-Recommended for patients with normal renal function#N#-With or without gentamicin, recommended for NVE due to highly penicillin-susceptible VGS or S gallolyticus (bovis)#N#---The 2-week regimen (with gentamicin) is not intended for patients with known cardiac/extracardiac abscess, CrCl less than 20 mL/min, impaired 8th cranial nerve function, or Abiotrophia, Granulicatella, or Gemella species infection.#N#-With or without gentamicin (penicillin-susceptible strain [MIC up to 0.12 mcg/mL]) or with gentamicin (relatively/fully penicillin-resistant strain [MIC greater than 0.12 mcg/mL]), recommended for prosthetic valve (or other prosthetic material) infection due to VGS or S gallolyticus (bovis)#N#-With ampicillin, recommended for NVE or prosthetic valve (or other prosthetic material) infection due to Enterococcus species by a strain susceptible to penicillin and gentamicin (if able to tolerate beta-lactam therapy)#N#-With ampicillin, recommended for NVE or prosthetic valve (or other prosthetic material) infection due to Enterococcus species by a strain susceptible to penicillin and resistant to aminoglycosides or streptomycin-susceptible gentamicin-resistant (if able to tolerate beta-lactam therapy)#N#-Recommended as preferred therapy for NVE or prosthetic valve (or other prosthetic material) infection due to HACEK microorganisms#N#---HACEK indicates Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens, and Kingella species#N#-With azithromycin, recommended regimen for the treatment of gonococcal endocarditis#N#---The patient's sexual partner (s) should also be evaluated/treated.#N#-Current guidelines should be consulted for additional information.
How often should I take penicillin?
AHA Recommendations:#N#1 year or older: 100 mg/kg/day IV in divided doses every 12 hours OR 80 mg/kg IV every 24 hours#N#Maximum dose: 4 g/day#N#Duration of therapy: At least 4 to 6 weeks#N#US CDC Recommendations for Adolescents:#N#-Gonococcal endocarditis: 1 to 2 g IV every 12 to 24 hours for at least 4 weeks#N#Comments:#N#-Daily dosage should be administered in divided doses twice a day if over 2 g/day.#N#-Recommended regimen (and an alternative regimen) for infective endocarditis due to highly penicillin G-susceptible streptococci (minimum bactericidal concentration [MBC] up to 0.1 mcg/mL)#N#-With ampicillin (for aminoglycoside-resistant enterococci or aminoglycoside-intolerant patient) or gentamicin (not for enterococcal endocarditis), recommended as an alternative regimen for infective endocarditis due to relatively penicillin-resistant streptococci (MBC at least 0.2 mcg/mL)#N#-With gentamicin, recommended regimen for infective endocarditis due to gram-negative enteric bacilli#N#-Recommended regimen for infective endocarditis due to HACEK group#N#---HACEK organisms include Haemophilus species, Aggregatibacter species, C hominis, E corrodens, and Kingella species.#N#-With azithromycin, recommended regimen for the treatment of gonococcal endocarditis in adolescents#N#---The patient's sexual partner (s) should also be evaluated/treated.#N#-Pediatric dose should not exceed adult dose.#N#-Current guidelines should be consulted for additional information.
How long does septicemia treatment last?
Usual Adult Dose for Septicemia. 1 to 2 g IV or IM once a day (or in equally divided doses twice a day) Duration of therapy: 4 to 14 days. -Complicated infections: Longer therapy may be required.
Is cephalosporin a contraindication?
CONTRAINDICATIONS:# N#-Known hypersensitivity to the active component, any of the ingredients, or any other cephalosporin#N#---According to some manufacturers: History of anaphylaxis to the active component, cephalosporin antibacterials, penicillins, or other beta-lactam antibacterials#N#-Neonates (up to 28 days of age) requiring (or expected to require) treatment with IV solutions containing calcium (including continuous calcium-containing infusions [e.g., parenteral nutrition]) due to risk of ceftriaxone-calcium precipitate#N#-Premature neonates up to postmenstrual age of 41 weeks (gestational age plus chronological age)#N#-Hyperbilirubinemic neonates#N#-IV administration of ceftriaxone solutions containing lidocaine#N#-Contraindications to lidocaine (when used as a solvent with this drug for IM injection)#N#Consult WARNINGS section for additional precautions.
What is ceftriaxone used for?
Ceftriaxone is used to treat a wide variety of bacterial infections. This medication belongs to a class of drugs known as cephalosporin antibiotics. It works by stopping the growth of bacteria.This drug is not recommended for use in newborns with high blood bilirubin levels and premature infants due to increased risk of side effects. Ask the doctor or pharmacist for details.
Can ceftriaxone cause blood problems?
If ceftriaxone is mixed with a numbing medication (such as lidocaine) before injection into a muscle, it may rarely cause a serious blood problem (methemoglobinemia). Get medical help right away if you have any very serious side effects, including: pale/gray/blue skin, fast heartbeat, shortness of breath.
Can you mix ceftriaxone with calcium?
If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Avoid mixing ceftriaxone with IV fluids that have calcium in them (such as Ringer's solution, Hartmann's solution, parenteral nutrition -TPN/PPN). Consult your pharmacist for details about the safe use of IV calcium products in infants, children, and adults (see Precautions section). Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
Can you take ceftriaxone if you are allergic to it?
Before using ceftriaxone, tell your doctor or pharmacist if you are allergic to it; or to other antibiotics (such as penicillins, other cephalosporins); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
