What is biological treatment?
STAT3 is a biologically relevant therapeutic target in H3K27M-mutant DMG. STAT3 inhibition should be considered in future clinical trials. ... Treatment of patient-derived intracranial xenografts with WP1066, a STAT3 pathway inhibitor currently in clinical use for pediatric brain tumors, resulted in stasis of tumor growth and increased overall ...
How useful is biological research in treating psychological disorders?
Jun 18, 2012 · Biologic therapy is also very important in the treatment of rare genetic diseases. This will probably only become more important in the future as more and more genetic therapies become available. For example, some biologic therapies to treat rare diseases include enzyme replacement therapy for Gaucher disease, blood clotting factors for hemophilia, or …
Why is it important to study the biological basis of behavior?
It is important to note that raw sewage discharges into a receiving water also present additional problems from harmful human enteric microbes, called pathogens, that can ... (secondary treatment). With biological treatment processes, the same . 32 organisms that occur naturally in the environment are grown under controlled conditions in the ...
What is biological wastewater treatment system?
Apr 01, 2019 · What is a biological wastewater treatment system? In a simplified, top-level answer to this question, a biological wastewater treatment system is a technology that primarily uses bacteria, some protozoa, and possibly other specialty microbes to clean water. When these microorganisms break down organic pollutants for food, they stick together, which creates a …
How do you know if something is biologically significant?
Another way to determine if the findings in a paper have biological relevance is to look for other papers that show similar results. If a result is “real” it should be found by other scientists who will build on it and publish more papers.Nov 7, 2018
Why hypothesis testing is so important in the biological sciences?
Hypothesis testing is the process used to evaluate the strength of evidence from the sample and provides a framework for making determinations related to the population, ie, it provides a method for understanding how reliably one can extrapolate observed findings in a sample under study to the larger population from ...Sep 5, 2006
What is significant difference biology?
A "significant difference" means that the results that are seen are most likely not due to chance or sampling error. In any experiment or observation that involves sampling from a population, there is always the possibility that an observed effect would have occurred due to sampling error alone.
Does statistical significance always translate into real world biological meaning?
"…a statistically significant difference is not necessarily biologically significant. By this we mean that it may not be interesting from a biological point of view or useful from a practical point of view.
Why is hypothesis testing important in healthcare?
Abstract. “Hypothesis testing” is an integral and most important component of research methodology, in all researches, whether in medical sciences, social sciences or any such allied field. It is a guideline in planning, implementation and getting final results thereof, in undertaking any research work.Jan 11, 2016
When should hypothesis testing be used?
Hypothesis testing is generally used when you are comparing two or more groups. For example, you might implement protocols for performing intubation on pediatric patients in the pre-hospital setting.
What does biologically significant mean?
“Biological significance” (as contrasted with statistical significance) refers to a statistically significant effect that has a noteworthy impact on health or survival.
What does biological relevance mean?
A biologically relevant effect can be defined as an effect considered by expert judgement as important and meaningful for human, animal, plant or environmental health. It therefore implies a change that may alter how decisions for a specific problem are taken.Sep 8, 2011
What does statistical significance mean biology?
Statistical significance refers to the claim that a result from data generated by testing or experimentation is likely to be attributable to a specific cause.
Does statistical significance mean clinical significance?
While statistical significance indicates the reliability of the study results, clinical significance reflects its impact on clinical practice.
What is statistical significance in epidemiology?
Statistical significance: the likelihood that a relationship between two prevalence variables is caused by something other than chance.
What is clinical significance and statistical significance?
The main difference between statistical and clinical significance is that the clinical significance observes dissimilarity between the two groups or the two treatment modalities, while statistical significance implies whether there is any mathematical significance to the carried analysis of the results or not.
Why are biologics important?
Biologic therapies are also very important for cancer treatment, and many continue to be developed. There are many different types of these treatments. Sometimes they are used as a first-line treatment. Other times they are used after other treatments have failed, or in advanced cancers.
What is the biologic therapy for rheumatoid arthritis?
Don’t hesitate to ask your healthcare provider if you have questions about the particular biologic therapy relevant to you. As an example, tocilizumab (trade name Actemra), a biologic used to treat rheumatoid arthritis, belongs to a class of biologic therapies called monoclonal antibodies.
What is the best treatment for autoimmune disease?
One of the most common types of modern biologic therapies for autoimmune disease is the TNF blocker. TNF blockers include the popular drugs etanercept (Enbrel), adalimumab (Humira), and infliximab (Remicade). These drugs all block the downstream inflammatory effects of an immune molecule called TNF-alpha.
What is the oldest biologic?
The oldest forms of biologics have been around for many years, such as the vaccines developed in the 19 th century. Insulin was another relatively early biologic therapy.
What are the side effects of biologics?
In some cases, these side effects are quite mild, such as a rash. Some other common side effects might include respiratory infections, flu-like reactions, or redness at the injection site.
How are monoclonal antibodies made?
These particular monoclonal antibodies are produced through a series of steps, beginning with early production of antibo dies in mice. Then scientists modify these antibodies, replacing much of them with portions of antibodies from humans. Inside the laboratory, many identical copies of these new antibodies are made.
What is biosimilar therapy?
What Are Biosimilars? "Biologics" refer to any type of medical therapy that is derived from living organisms such as humans, animals, or microorganisms. This contrasts with traditional non-biologic pharmaceutical drugs, which are synthesized in a laboratory via chemical processes without using parts of living things.
What are the different types of wastewater treatment?
Typically broken out into three main categories, biological wastewater treatment can be: 1 aerobic, when microorganisms require oxygen to break down organic matter to carbon dioxide and microbial biomass 2 anaerobic, when microorganisms do not require oxygen to break down organic matter, often forming methane, carbon dioxide, and excess biomass 3 anoxic, when microorganisms use other molecules than oxygen for growth, such as for the removal of sulfate, nitrate, nitrite, selenate, and selenite
When was the moving bed bioreactor invented?
Moving bed bioreactors, or MBBRs, invented in the late 1980s in Norway, already has been applied in over 800 applications in more than 50 countries, with approximately half treating domestic wastewater and half treating industrial wastewater.
What is an MBR system?
MBRs primarily target BOD and total suspended solids (TSS). MBR system design varies depending on the nature of the wastewater and the treatment goals, but a typical MBR might consist of aerobic (or anaerobic) treatment tanks, an aeration system, mixers, a membrane tank, a clean-in-place system, and either a hollow fiber or flat sheet ...
How are suspended flocs removed from wastewater?
The suspended flocs enter a settling tank and are removed from the wastewater by sedimentation. Recycling of settled solids to the aeration tank controls levels of suspended solids, while excess solids are wasted as sludge.
What happens when a pollutant is elevated?
When pollutant levels are elevated, BOD can deplete the oxygen needed by other aquatic organisms to live, leading to algal blooms, fish kills, and harmful changes to the aquatic ecosystem where the wastewater is discharged. Because of this, many facilities are required to treat their wastes, perhaps biologically, ...
What does high BOD mean?
High levels of BOD indicate an elevated concentration of biodegradable material present in the wastewater and can be caused by the introduction of pollutants such as industrial discharges, domestic fecal wastes, or fertilizer runoff. When pollutant levels are elevated, BOD can deplete the oxygen needed by other aquatic organisms to live, ...
What is a fixed bed wastewater system?
A well-engineered fixed-bed will allow wastewater to flow through the system without channeling or plugging. Chambers can be aerobic and still have anoxic zones to achieve aerobic carbonaceous removal and full anoxic denitrification at the same time.
Why is biological research important?
Biological research has helped yield useful treatments for a variety of psychological disorders .
What is biological psychology?
The Biological Perspective. This field of psychology is often referred to as biopsychology or physiological psychology. This branch of psychology has grown tremendously in recent years and is linked to other areas of science including biology, neurology, and genetics.The biological perspective is essentially a way of looking at human problems ...
What is biological perspective?
The biological perspective is a way of looking at psychological issues by studying the physical basis for animal and human behavior. It is one of the major perspectives in psychology and involves such things as studying the brain, immune system, nervous system, and genetics.
What do biopsychologists study?
Biopsychologists study many of the same things that other psychologists do, but they are interested in looking at how biological forces shape human behaviors. Some topics that a psychologist might explore using this perspective include: Analyzing how trauma to the brain influences behaviors.
What is the difference between a biological and social perspective?
A psychologist with a social perspective might look at the group dynamics and pressures that contribute to such behavior. The biological viewpoint, on the other hand, would involve looking at the biological roots that lie behind aggressive behaviors. Someone who takes the biological perspective might consider how certain types ...
Why is it important to assess differences and similarities in twins?
Assessing the differences and similarities in twins to determine which characteristics are tied to genetics and which are linked to environmental influences. This perspective has grown considerably in recent years as the technology used to study the brain and nervous system has grown increasingly advanced.
How does natural selection affect behavior?
Natural selection influences whether certain behavior patterns are passed down to future generations. Behaviors that aid in survival are more likely to be passed down while those that prove dangerous are less likely to be inherited. Consider an issue like aggression.
