Treatment FAQ

a patient is diagnosed with syphilis. what is the treatment of choice for this condition?

by Winona Labadie DDS Published 3 years ago Updated 2 years ago
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When diagnosed and treated in its early stages, syphilis is easy to cure. The preferred treatment at all stages is penicillin, an antibiotic medication that can kill the organism that causes syphilis. If you're allergic to penicillin, your doctor may suggest another antibiotic or recommend penicillin desensitization.Sep 25, 2021

Common tests & procedures

Syphilis can be diagnosed by testing samples of: Blood. Blood tests can confirm the presence of antibodies that the body produces to fight infection. The antibodies to the syphilis-causing bacteria remain in your body for years, so the test can be used to determine a current or past infection. Cerebrospinal fluid.

How is syphilis diagnosed and treated?

The nurse is preparing to administer medication therapy to a woman diagnosed with syphilis. The nurse would expect to administer: 1- miconazole. 3- metronidazole. 4- doxycycline. The nurse is developing a plan of care for a client who is receiving aggressive drug therapy for treatment of HIV. The goal of this therapy is to:

What medication would the nurse expect to administer to a syphilis?

Patients with treated primary or secondary syphilis. Patients treated for primary and secondary syphilis should have follow-up VDRL testing at 6, and 12 months after treatment. Patients with HIV infection should be monitored at 3, 6, 9, and 12 months, as they are known to have more rapid progression of disease.

What is the follow-up care for primary and secondary syphilis?

The primary goal of prevention is to limit the spread of syphilis. This entails counseling patients to use safe sex practices and advising patients who abuse intravenous (IV) drugs to never share needles and to use clean needles.

What is the primary goal of prevention of syphilis?

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What is the treatment of choice for syphilis?

Penicillin G, administered parenterally, is the preferred drug for treating patients in all stages of syphilis. The preparation used (i.e., benzathine, aqueous procaine, or aqueous crystalline), dosage, and length of treatment depend on the stage and clinical manifestations of the disease.

What is the recommended treatment for syphilis and gonorrhea?

Chlamydia, gonorrhoea and syphilis are all caused by bacteria and they are generally curable with antibiotics.

What penicillin is used for syphilis?

What is the treatment for syphilis? A single injection of long-acting Benzathine penicillin G can cure the early stages of syphilis. This includes primary, secondary, or early latent syphilis.

Which one of the following is treated with penicillin?

Penicillin is given to patients with an infection caused by bacteria. Some types of bacterial infections that may be treated with penicillin include pneumonia, strep throat, meningitis, syphilis and gonorrhea, according to the National Library of Medicine. It may also be used to prevent dental infections.

What test can confirm syphilis?

Blood. Blood tests can confirm the presence of antibodies that the body produces to fight infection. The antibodies to the syphilis-causing bacteria remain in your body for years, so the test can be used to determine a current or past infection. Cerebrospinal fluid.

How to prevent HIV infection?

Avoid sexual contact with new partners until the treatment is completed and blood tests indicate the infection has been cured. Notify your sex partners so that they can be tested and get treatment if necessary. Be tested for HIV infection.

Can you cure syphilis with penicillin?

When diagnosed and treated in its early stages, syphilis is easy to cure. The preferred treatment at all stages is penicillin, an antibiotic medication that can kill the organism that causes syphilis. If you're allergic to penicillin, your doctor may suggest another antibiotic or recommend penicillin desensitization.

What to do if you have syphilis?

If you might have syphilis, your doctor will order a blood test. If this blood test is positive, the lab typically performs a second test on your blood to confirm that you have syphilis. If you have syphilis, you need treatment.

What happens if you catch syphilis in a late stage?

If the syphilis was caught in a late stage, it may have affected your body in other ways. You may need other medical tests. People also need follow-up syphilis blood tests to make sure the syphilis treatment worked. Taking good care of yourself also plays an important role in your treatment.

How long does it take to get penicillin for syphilis?

Here’s how you may get the antibiotic: Early stage: One shot of penicillin. Late stage: Three shots of penicillin, with one shot given each week for three weeks. Syphilis affects your nervous system: Penicillin given through an IV (intravenous) infusion, with treatment given once a week for two weeks. To treat syphilis with penicillin, you need ...

How long after syphilis treatment can you have sex?

To treat syphilis with penicillin, you need a shot or IV infusion. Taking penicillin pills cannot cure you. You should not have sex for at least 1 week after treatment and until all symptoms have gone away.

Can you use latex condoms for syphilis?

When you start having sex again, use latex condoms and/or dental dams to prevent getting syphilis again or other sexually transmitted diseases. While the right antibiotic can cure syphilis, it cannot undo damage already done. If syphilis caused hearing loss, you’ll continue to have hearing loss after being treated.

Can you take doxycycline for syphilis?

If your doctor decides to treat you with one of these antibiotics, you will need several follow-up appointments. These antibiotics can be less effective at treating syphilis.

Do you need a follow up appointment for syphilis?

Others get re-infected. During your follow-up appointments, you’ll have: A blood test to make sure you no longer have syphilis. Other medical tests if the disease was caught late.

Nontreponemal Tests and Traditional Algorithm

False-positive nontreponemal test results can be associated with multiple medical conditions and factors unrelated to syphilis, including other infections (e.g., HIV), autoimmune conditions, vaccinations, injecting drug use, pregnancy, and older age ( 566, 569 ).

Treponemal Tests and Reverse Sequence Algorithm

The majority of patients who have reactive treponemal tests will have reactive tests for the remainder of their lives, regardless of adequate treatment or disease activity. However, 15%–25% of patients treated during the primary stage revert to being serologically nonreactive after 2–3 years ( 570 ).

Cerebrospinal Fluid Evaluation

Further testing with CSF evaluation is warranted for persons with clinical signs of neurosyphilis (e.g., cranial nerve dysfunction, meningitis, stroke, acute or chronic altered mental status, or loss of vibration sense).

Special Considerations

Parenteral penicillin G is the only therapy with documented efficacy for syphilis during pregnancy. Pregnant women with syphilis at any stage who report penicillin allergy should be desensitized and treated with penicillin (see Management of Persons Who Have a History of Penicillin Allergy).

Management of Sex Partners

Sexual transmission of T. pallidum is thought to occur only when mucocutaneous syphilitic lesions are present. Such manifestations are uncommon after the first year of infection.

What is STI characterized by?

1- "This STI is characterized by an infection of your cervix. ". 2- "This STI is an infection that will cause itching in the genital area.". 3- "This STI is an infection that results in ulcers in the genital area.". 4- "This STI is an infection that will result in the formation of genital warts.". 1.

What is a nurse's goal in HIV treatment?

The goal of this therapy is to: 1- promote the progression of disease. 2- intervene in late-stage AIDS. 3- improve survival rates. 4- conduct additional drug research. Click card to see definition 👆.

What does it mean when a young woman has a frothy discharge?

1. A young woman presents with vaginal itching and irritation of recent onset. Her labia are swollen, and she has a frothy yellowish discharge with an unpleasant smell and a pH of 6.8. She has been celibate during the last six months and has been taking antibiotics for a throat infection.

What is the most common infectious cause of infertility?

3- Antiviral drug regimes will cure this infection. 4- The new recombinant human papillomavirus vaccine will prevent the infection. 1.

What is the best treatment for syphilis?

Penicillin is the drug of choice to treat syphilis. Doxycycline is the best alternative for treating early and late latent syphilis. Syphilis associated with HIV infection does not require any enhanced antimicrobial therapy.

How long after syphilis treatment should you have a VDRL test?

Patients treated for primary and secondary syphilis should have follow-up VDRL testing at 6, and 12 months after treatment. Patients with HIV infection should be monitored at 3, 6, 9, and 12 months, as they are known to have more rapid progression of disease.

How long does it take for a spirochete to clear?

The reaction is common, develops within several hours after beginning antibiotic treatment, and usually clears within 24 hours after onset. Its exact etiology is unclear, although it may be due to an immunological reaction to the rupture of spirochetes.

Is penicillin a syphilis drug?

Penicillin. Penicillin was established as an effective treatment for syphilis before the widespread use of randomized clinical trials. [ 26] . The treatment guidelines published by the CDC (see current CDC recommendations) are based largely on uncontrolled trials and expert opinion.

Can CSF be used for neurosyphilis?

CSF testing to detect neurosyphilis is strongly recommended in patients with tertiary syphilis or with neurological signs or symptoms consistent with neurosyphilis and in patients without symptoms whose serologic titers do not decline appropriately after being treated with recommended therapy.

Is azithromycin effective in syphilis?

Although azithromycin is effective, resistance is increasing in the United States, with some areas reporting up to 84% resistance; therefore, azithromycin should be used only in areas of low resistance or in early syphilis with close clinic al follow-up. [ 19, 36] Jarisch-Herxheimer reaction.

Can penicillin be used for syphilis?

Penicillin is the only recommended therapy for neurosyphilis, congenital syphilis, or syphilis during pregnancy. Rarely, T pallidum has been found to persist following adequate penicillin therapy; however, there is no indication that the organism has acquired resistance to penicillin.

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Diagnosis

Treatment

Clinical Trials

Medically reviewed by
Dr. Karthikeya T M
Your provider may recommend one or more of these diagnostic tests and procedures as part of an evaluation.
It can be diagnosed by blood test and spinal fluid tests.
Common tests & procedures

Physical examination: Physical examination of the rashes or sores.

Blood test: Blood test to detect bacteria.

Fluid examination: Examination of the fluid from the sore.

Spinal tap (lumbar puncture): Extracting the spinal fluid to examine for infection in case of nervous system problems.

Coping and Support

Preparing For Your Appointment

Nontreponemal Tests and Traditional Algorithm

  • Medication
    When diagnosed and treated in its early stages, syphilis is easy to cure. The preferred treatment at all stages is penicillin, an antibiotic medication that can kill the organism that causes syphilis. If you're allergic to penicillin, your doctor may suggest another antibiotic or recommend penicillin d…
  • Treatment follow-up
    After you're treated for syphilis, your doctor will ask you to: 1. Have periodic blood tests and exams to make sure you're responding to the usual dosage of penicillin. Your specific follow-up will depend on the stage of syphilis you're diagnosed with. 2. Avoid sexual contact with new part…
See more on mayoclinic.org

Treponemal Tests and Reverse Sequence Algorithm

  • Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
See more on mayoclinic.org

Cerebrospinal Fluid Evaluation

  • Finding out you have syphilis can be extremely upsetting. You might experience anger if you feel you've been betrayed, or shame if you think you've infected others. However, hold off placing blame. Don't assume that your partner has been unfaithful to you. One (or both) of you may have been infected by a past partner.
See more on mayoclinic.org

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