Treatment FAQ

with lupus, what approach to treatment would you take?

by Dr. Lorena White Published 2 years ago Updated 2 years ago
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Most people with lupus take hydroxychloroquine throughout their lives. It helps control lupus symptoms with very few side effects. Hydroxychloroquine may also help prevent blood clots and organ damage from lupus.

Lupus is mainly treated with medicine. The types of drugs that have been used to treat lupus include NSAIDs, corticosteroids and other immune system suppressing drugs, hydroxychloroquine, and the newest lupus drug, Benlysta. Lupus medications work in different ways.

Full Answer

What is the best approach to treating my lupus?

The best approach to treating your lupus is a plan tailored to your specific needs. It should consider the type of lupus you have, the severity of your inflammation and the damage to your organs that has occurred. Keep in mind that this plan may take some time to create and may need to be adjusted as your symptoms and your needs change.

What medications are used to treat lupus?

Corticosteroids like prednisone, prednisolone, methylprednisolone, and hydrocortisone Immunosuppressives like cyclophosphamide (Cytoxan®), methotrexate (Rheumatrex™), and azathioprine (Imuran®) People with lupus may also need other medicines to treat conditions often seen with the disease.

Can Mayo Clinic help with lupus?

Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition. If you receive care for lupus at Mayo Clinic, consider registering for this online class: Living Well with Lupus. Take steps to care for your body if you have lupus.

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What is the best treatment of lupus?

Steroids Synthetic cortisone medications are some of the most effective treatments for reducing the swelling, warmth, pain, and tenderness associated with the inflammation of lupus. Cortisone usually works quickly to relieve these symptoms.

What is the first treatment for lupus?

Early Progress With Lupus Treatment Involves Antimalarials and Corticosteroids. The first medication used for lupus, quinine (an antimalarial), was described by Payne in 1894 (Payne, 1894).

Is there a holistic approach to lupus?

Omega-3 fatty acids can curb inflammation. In addition, several studies have also found that they improve lupus symptoms. 2 You can increase your omega-3 intake by eating oily fish (such as salmon and sardines), flaxseeds, or by taking a daily omega-3 supplement.

How are patients managed with lupus?

In patients with mild-to-moderate lupus, NSAIDs, anti-malarial agents, and corticosteroids are commonly used to treat signs and symptoms. As the disease progresses and clinical manifestations worsen, high-dose corticosteroids and immunosuppressive agents are used to help control disease progression.

What is lupus and how is it treated?

Lupus (Systemic Lupus Erythematosus) Lupus is an autoimmune disease that can cause joint pain, fever, skin rashes and organ damage. There's currently no cure for lupus and it requires life-long management. Lupus is most commonly seen in women — typically between the ages of 15 and 45.

What is the latest treatment for lupus?

People living with systemic lupus erythematosus (SLE) have a new drug option. The U.S. Food and Drug Administration approved anifrolumab (Saphnelo) in early August — the first new drug approved for SLE in 10 years.

How does a naturopath treat lupus?

The treatment of lupus with Naturopathic medicine involves evaluation of the whole body, including how it is affected by inflammation. Naturopathic treatment of lupus may involve the use of acupuncture, homeopathy, lifestyle and stress counselling, and herbal therapies to address immune system over-activation.

Can you live with lupus without treatment?

If left untreated, it can put you at risk of developing life-threatening problems such as a heart attack or stroke. In many cases, lupus nephritis does not cause any noticeable symptoms. However, this does not mean the condition is not dangerous, as the kidneys could still be being damaged.

How can you prevent lupus from getting worse?

Other things you can do include:Visit your doctor regularly. ... Get plenty of rest. ... Watch out for stress. ... Avoid physical stress. ... Avoid sunlight whenever possible. ... Take your medications as prescribed. ... Be careful with certain foods and supplements.

What is standard therapy for SLE?

Nowadays, antimalarials are the basic treatment for every patient with SLE, whereas glucocorticoids should only be used when acutely indicated. If reduction or tapering of glucocorticoids proves impossible, extended immunosuppression with azathioprine, methotrexate, or mycophenolate mofetil is recommended.

How to treat lupus?

Maintaining a healthy lifestyle can help manage your lupus symptoms. Here are a few easy ways to take care of yourself: 1 Eat a heart-healthy diet. 2 Maintain a healthy weight. 3 Exercise several times a week. 4 Reduce your sun exposure by staying out of the sun as much as possible, wearing clothes that cover your skin and using sunscreen of SPF 100. 5 See your doctor for infections. 6 Don’t smoke.

What to do if you have lupus?

It’s also important to have regular exams and lab tests to track your lupus and adjust your treatment as needed.

What are some medications that help with kidney lupus?

Antibiotics for infections. Antihypertensive drugs for high blood pressure. Statins for high cholesterol. Drugs for osteoporosis. Vitamin D to help improve kidney lupus.

Does cortisone help with lupus?

It reduces flares by 50 percent and may also help prevent blood clots . Corticosteroids and immune suppressants: often recommended for people with serious or life-threatening problems such as kidney inflammation, lung, heart or central nervous system lupus.

What is the best treatment for lupus?

Corticosteroids. Prednisone and other types of corticosteroids can counter the inflammation of lupus. High doses of steroids such as methylprednisolone (Medrol) are often used to control serious disease that involves the kidneys and brain.

How to help someone with Lupus?

Connect with others who have lupus. Talk to other people who have lupus. You can connect through support groups in your community or through online message boards. Other people with lupus can offer unique support because they're facing many of the same obstacles and frustrations that you're facing.

What does a low platelet count mean in a lupus test?

Erythrocyte sedimentation rate. This blood test determines the rate at which red blood cells settle to the bottom of a tube in an hour.

What are the challenges of living with Lupus?

The challenges of living with lupus increase your risk of depression and related mental health problems, such as anxiety, stress and low self-esteem. To help you cope, try to:

What are the side effects of lupus?

Side effects include weight gain, easy bruising, thinning bones, high blood pressure, diabetes and increased risk of infection. The risk of side effects increases with higher doses and longer term therapy. Immunosuppressants. Drugs that suppress the immune system may be helpful in serious cases of lupus.

What are the tests for Lupus?

Laboratory tests. Blood and urine tests may include: Complete blood count. This test measures the number of red blood cells, white blood cells and platelets as well as the amount of hemoglobin, a protein in red blood cells. Results may indicate you have anemia, which commonly occurs in lupus. A low white blood cell or platelet count may occur in ...

Can you take care of Lupus at Mayo Clinic?

If you receive care for lupus at Mayo Clinic, consider registering for this online class: Living Well with Lupus. Diagnosis and treatment. Take steps to care for your body if you have lupus. Simple measures can help you prevent lupus flares and, should they occur, better cope with the signs and symptoms you experience.

What is the best medicine for Lupus?

The most common medicines used to treat lupus include: Anticoagulants to help prevent blood clots. Anti-inflammatories to help with. Antimalarials to protect skin from rashes and UV light. Biologics to help your immune system work correctly. Immunosuppressives to help keep your immune system from attacking your body.

What kind of doctor treats lupus?

A special doctor called a rheumatologist can help you find the right treatment plan — and refer you to other types of doctors to treat specific symptoms. Learn more about the types of doctors who treat lupus.

Is lupus a team effort?

If you’ve been diagnosed with lupus, treatment is probably your biggest concern. Treating lupus is a team effort — so you and your doctors will work together to find the treatment plan that’s right for you.

Is there a cure for Lupus?

While there’s no cure for lupus right now, having the right treatment plan can help: Control your symptoms — like joint pain, swelling, and feeling tired. Keep your immune system (the part of the body that fights off bacteria and viruses) from attacking your body. Protect your organs from damage.

Can you take Lupus meds while pregnant?

Some lupus medicines aren’t safe to take when you’re pregnant or breastfeeding. If you’re pregnant or planning to get pregnant, talk with your doctors about which treatments are safe for you and your baby. Learn more about medicines used to treat lupus: Read our detailed guide to lupus medicines. Find out how to get the most from your medicines.

What is the best medication for lupus?

They do this by lessening the immune system’s response. Prednisone is the most commonly prescribed steroid for lupus. Prednisolone and methylprednisolone (Medrol®) are similar to prednisone.

What causes lupus to die?

Infections are one of the leading causes of death in people with lupus. Avascular necrosis of bone. This occurs most often in the hip—it is the destruction of the bone itself and is quite painful. Relief from pain often requires total joint replacement. Osteoporosis (bones become fragile and more likely to break).

What is the body's most powerful anti-inflammatory hormone?

Cortisol helps regulate blood pressure and the immune system. It is also the body’s most powerful anti-inflammatory hormone. Corticosteroids prescribed for autoimmune diseases are different from anabolic steroids. Anabolic steroids are sometimes used by weightlifters and other athletes to increase strength.

What is the purpose of corticosteroids?

They are designed to work like cortisol, a naturally occurring hormones produced by the adrenal glands. Hormones are the body’s chemical messengers that regulate most of the body’s functions.

Why do people with variations in two genes need to take warfarin?

Specifically, people with variations in two genes may need lower warfarin doses due to differences in how the body breaks down (metabolizes) warfarin and regulates the ability of warfarin to prevent blood from clotting. For this reason, the dosage and administration of warfarin must be individualized for each person.

What is the best treatment for rheumatoid arthritis?

Methotrexate (Rheumatrex™) Originally developed as a chemotherapy drug (to treat cancer) and used as an immunosuppressant (to treat lupus). Known as the "gold standard" -- the best drug -- for the treatment of rheumatoid arthritis.

Do you need an eye exam for Lupus?

However, as a precaution, people treated with antimalarials should get an eye exam before or soon after starting the drug. They should also visit an eye doctor (ophthalmologist) annually.

How to treat lupus?

Lifestyle Changes for Lupus 1 Eat a healthy diet. Although no specific meal plan has been shown to help with lupus symptoms, aim for a diet high in fruits and vegetables and low in unhealthy fats. Ask your doctor to suggest additional dietary changes based on your personal health. For instance, if you have bone loss, your doctor may recommend increasing calcium and vitamin D. If you have kidney problems, your doctor might suggest eating a low-salt diet. 2 Exercise. Exercise is key if you have lupus. It can help improve your mood, boost energy, lower your risk of heart disease, and sharpen your thinking. 3 Reduce stress. In many people, stress can trigger flares. Use techniques like meditation, biofeedback, yoga, and breathing exercises to cut down on stress. Cognitive-behavioral therapy can help as well. 4 Rest. People with lupus might need more rest than the average person. If you can, build time for rest into the day and allow for 8 to 10 hours of sleep a night.

What to do if you have lupus?

If you have kidney problems, your doctor might suggest eating a low-salt diet. Exercise. Exercise is key if you have lupus.

What is the best medicine for lupus?

Hydroxychloroquine ( Plaquenil) is used to treat malaria, and researchers have found that this drug also helps with lupus flares. These drugs work well with mild to moderate cases of lupus. They can help ease lupus symptoms such as joint swelling and skin rashes.

What are the medications for Lupus?

These can include statins, diuretics, anticoagulants, drugs to strengthen bones, blood pressure medicines, antibiotics, stimulants, and others .

What are the side effects of lupus?

The most common side effects are nausea, diarrhea, and fever. Corticosteroids. Oral steroids – such as prednisone and prednisolone -- can be a lifesaving treatment for people with lupus. During serious lupus flares that affect organs such as the kidneys, high doses of steroids can quickly control symptoms.

How to get rid of lupus flares?

Reduce stress. In many people, stress can trigger flares. Use techniques like meditation, biofeedback, yoga, and breathing exercises to cut down on stress.

Can lupus cause side effects?

As many people with lupus know, the list of possible side effects from lupus medications can be alarming. However, Bermas says that fears about side effects can get blown out of proportion. Although lupus drugs can have serious side effects, many are quite rare and most can be well managed,she says.

What is the drug used to treat lupus?

Rapamycin (Sirolimus, Rapamune®), is used in combination with other medications to prevent rejection of kidney transplants. This treatment has unique effects on T Cells and inhibits a certain form of a control point in the cell called MTOR (Mammalian Target of Rapamycin ) that is known to be imbalanced in lupus.

What is the purpose of anti-interferon-alpha?

Anti-interferon-alpha antibody targets interferon-alpha (INF-α), a chemical the body makes to fight viruses. Too much IFN-α can lead to immune problems, and levels of INF-α are higher than normal in lupus and other autoimmune disorders. Stopping the overproduction of INF-α may reduce disease activity in lupus.

Is Lupus a drug?

Many drugs, both old and new, are now being studied in people with lupus. The drugs described below are not a complete list of all the drugs currently in development for lupus, and they may not all end up as approved medications. However, the variety of scientific approaches reflects the growing interest in lupus at all levels of the biomedical and pharmaceutical industry.

Is Abatacept approved for Lupus?

Some have already been approved by the FDA for treating other conditions, and are now being studied in lupus. Other treatments listed here are not yet approved for any diseases, and are not on the market or available to any individuals except those in clinical trials. Abatacept (Orencia®) targets the T cells, a type of white blood cell ...

Is there a guarantee that a drug being studied will provide any benefit?

There is no guarantee that a drug being studied will provide any benefit, and of course there are always risks with all drugs, whether investigational treatments in trials or standard of care treatments, commonly prescribed in general medical care. In early phase clinical trials, less is known about the side effects to be expected.

Is a placebo a double blind study?

Generally, as part of the clinical trial designs, some of the volunteers receive placebo (an inactive substance). These trials are also "double blind" meaning that neither the investigating team or the volunteer know whether they are receiving the real treatment or the placebo--at least not until the study is over.

Can you get lupus without clinical trial volunteers?

This is done to make sure the results are scientific. There will be no new drugs for lupus without clinical trial volunteers! While participation in research studies is not for everyone, people with lupus, as well as people without lupus, can make a profound contribution by participating in clinical trials.

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Diagnosis

Treatment

Clinical Trials

  • Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
See more on mayoclinic.org

Lifestyle and Home Remedies

  • Take steps to care for your body if you have lupus. Simple measures can help you prevent lupus flares and, should they occur, better cope with the signs and symptoms you experience. Try to: 1. See your doctor regularly.Having regular checkups instead of only seeing your doctor when your symptoms worsen may help your doctor prevent flares, and can be useful in addressing routine …
See more on mayoclinic.org

Alternative Medicine

  • Sometimes people with lupus seek alternative or complementary medicine. There aren't any alternative therapies that have been shown to alter the course of lupus, although some may help ease symptoms of the disease. Discuss these treatments with your doctor before initiating them on your own. He or she can help you weigh the benefits and risks and t...
See more on mayoclinic.org

Coping and Support

  • If you have lupus, you're likely to have a range of painful feelings about your condition, from fear to extreme frustration. The challenges of living with lupus increase your risk of depression and related mental health problems, such as anxiety, stress and low self-esteem. To help you cope, try to: 1. Learn all you can about lupus.Write down any questions you have about lupus as they occu…
See more on mayoclinic.org

Preparing For Your Appointment

  • You're likely to start by seeing your primary care doctor, but he or she may refer you to a specialist in the diagnosis and treatment of inflammatory joint conditions and immune disorders (rheumatologist). Because the symptoms of lupus can mimic so many other health problems, you may need patience while waiting for a diagnosis. Your doctor must rule out a number of other ill…
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