Treatment FAQ

why does osteomyelitis require longer treatment

by Dr. Dejah Kohler DVM Published 3 years ago Updated 2 years ago

Medication

Osteomyelitis requires long-term care to prevent further complications, including care to prevent the following: 1 Fracturesof the affected bone 2 Stunted growth in children (if the infection has involved the growth plate) 3 Gangrene infection in the affected area

Procedures

So, no, osteomyelitis does not always need surgery, in fact, osteomyelitis should rarely need a knife if appropriate treatment interventions are implemented. Aletha Tippett MD is a family medicine and wound care expert, founder and president of the Hope of Healing Foundation®, family physician, and international speaker on wound care.

Self-care

Keywords: Osteomyelitis, long bones, antibiotics, debridement Osteomyelitis in long bones presents a variety of challenges depending on the infection's particular features (etiology, pathogenesis, extent of bone involvement, and duration) and the patient (infant, child, adult, or immunocompromised).

Nutrition

Many cases of osteomyelitis may be treated with antimicrobial therapy alone. One example is seen in pediatric osteomyelitis cases where the ability of the younger patient to resorb dead bone thereby removes the devitalized surfaces where bacteria can persist in a biofilm mode of growth (discussed later).

Why is long-term care necessary for osteomyelitis?

Does osteomyelitis always need surgery?

What are the challenges in the treatment of osteomyelitis in long bones?

How is osteomyelitis treated with antimicrobial therapy alone?

How long should osteomyelitis be treated?

Traditionally, antibiotic treatment of osteomyelitis consists of a 4- to 6-week course. Animal studies and observations show that bone revascularization following debridement takes about 4 weeks. However, if all infected bone is removed, as in forefoot osteomyelitis, antibiotic therapy can be shortened to 10 days.

Does osteomyelitis require long term antibiotics?

Acute hematogenous osteomyelitis in children typically can be treated with a four-week course of antibiotics. In adults, the duration of antibiotic treatment for chronic osteomyelitis is typically several weeks longer. In both situations, however, empiric antibiotic coverage for S. aureus is indicated.

How long does it take to recover from osteomyelitis?

You'll usually take antibiotics for 4 to 6 weeks. If you have a severe infection, the course may last up to 12 weeks. It's important to finish a course of antibiotics even if you start to feel better. If the infection is treated quickly (within 3 to 5 days of it starting), it often clears up completely.

Why it is important that osteomyelitis be diagnosed and treated as soon as possible?

Bone is usually good at fighting infection, but trauma, bacteremia, surgery, or foreign body insertion may disrupt blood flow and lead to the development of osteomyelitis. Early diagnosis is very important because fast antibiotic delivery may prevent permanent bone loss.

How long is antibiotic treatment for osteomyelitis?

The duration of therapy for acute osteomyelitis is 4-8 weeks. The optimal duration of therapy for chronic osteomyelitis is uncertain, but treatment is usually administered for a minimum of 6 weeks.

What happens if osteomyelitis goes untreated?

What is osteomyelitis? Osteomyelitis is a bone infection caused by bacteria or fungi. It causes painful swelling of bone marrow, the soft tissue inside your bones. Without treatment, swelling from this bone infection can cut off blood supply to your bone, causing bone to die.

Can osteomyelitis lead to death?

Osteomyelitis complications may include: Bone death (osteonecrosis). An infection in your bone can impede blood circulation within the bone, leading to bone death.

Can osteomyelitis spread to the rest of the body?

When a person has osteomyelitis: Bacteria or other germs may spread to a bone from infected skin, muscles, or tendons next to the bone. This may occur under a skin sore. The infection can start in another part of the body and spread to the bone through the blood.

What complication of osteomyelitis is the most likely to occur?

The most common complication in children with osteomyelitis is recurrence of bone infection.

Why are bone infections hard to treat?

Bone infection can be difficult to treat because bacteria are constantly changing to fight the new antibiotics that are used to kill them. Some bacteria have been extremely difficult to kill, including methicillin-resistant Staphylococcus aureus species and vancomycin-resistant enterococci.

What is the gold standard for diagnosing osteomyelitis?

The gold standard for the diagnosis of osteomyelitis is bone biopsy with histopathologic examination and tissue culture. When the patient is clinically stable, one should consider delaying empiric antimicrobial treatment until bone biopsy is performed.

Can osteomyelitis be cured without surgery?

Non-surgical treatment of osteomyelitis requires a multidisciplinary team approach including primary care, infectious disease specialist care, nutritionist care and wound care. These wounds will require antibiotic therapy for a duration of six to eight weeks.

Who Is Affected by Osteomyelitis?

Osteomyelitis can affect both adults and children. The bacteria or fungus that can cause osteomyelitis, however, differs among age groups. In adult...

What Causes Osteomyelitis?

It can be caused by a variety of microbial agents (most common in staphylococcus aureus) and situations, including: 1. An open injury to the bone,...

What Are The Symptoms of Osteomyelitis?

The symptoms of osteomyelitis can include: 1. Pain and/or tenderness in the infected area. 2. Swelling, redness and warmth in the infected area. 3....

Why is it important to treat osteomyelitis?

The objective of treating osteomyelitis is to eliminate the infection and prevent the development of chronic infection. Chronic osteomyelitis can lead to permanent deformity, possible fracture, and chronic problems, so it is important to treat the disease as soon as possible.

What is osteomyelitis infection?

What is osteomyelitis? Osteomyelitis is a bacterial, or fungal, infection of the bone. Osteomyelitis affects about 2 out of every 10,000 people. If left untreated, the infection can become chronic and cause a loss of blood supply to the affected bone.

What is the disease that can cause bone tissue death?

Osteomyelitis. Osteomyelitis is an infection of the bone that can affect both adults and children. If left untreated, it can lead to bone tissue death over time. Appointments 216.444.2606. Appointments & Locations. Contact Us. Overview. Symptoms and Causes. Diagnosis and Tests.

How do you know if you have osteomyelitis?

The symptoms of osteomyelitis can include: Pain and/or tenderness in the infected area. Swelling, redness and warmth in the infected area. Fever. Nausea, secondarily from being ill with infection. General discomfort, uneasiness, or ill feeling. Drainage of pus (thick yellow fluid) through the skin.

How do antibiotics help the body?

Antibiotics help the body get rid of bacteria in the bloodstream that may otherwise re-infect the bone. The dosage and type of antibiotic prescribed depends on the type of bacteria present and the extent of infection.

Why are antibiotics ineffective?

The reason for this is that antibiotics are ineffective at reaching pockets of infected fluid as they have no blood supply. Antibiotic medications: Prescribing antibiotics is the first step in treating osteomyelitis. Antibiotics help the body get rid of bacteria in the bloodstream that may otherwise re-infect the bone.

What causes a bone to break out?

It can be caused by a variety of microbial agents (most common in staphylococcus aureus) and situations, including: An open injury to the bone, such as an open fracture with the bone ends coming out through the skin.

How to treat osteomyelitis?

Treating osteomyelitis: antibiotics and surgery. Osteomyelitis is best managed by a multidisciplinary team. It requires accurate diagnosis and optimization of host defenses, appropriate anti-infective therapy, and often bone débridement and reconstructive surgery.

How is osteomyelitis managed?

Osteomyelitis is best managed by a multidisciplinary team. It requires accurate diagnosis and optimization of host defenses, appropriate anti-infective therapy, and often bone débridement and reconstructive surgery.

Can osteomyelitis be chronic?

It can affect all ages and involve any bone. Osteomyelitis may become chronic and cause persistent morbidity. Despite new imaging techniques, diagnosis can be difficult and often delayed. Because infection can recur years after apparent "cure," "remission" is a more appropriate term.

What is the treatment for osteomyelitis?

Treatment consists of a combined surgical and medical approach, including long-duration antibiotic therapy, except in the case of amputation of the entire area of infected bone with residual uninfected proximalmargins.

How long does antibiotic treatment last for osteomyelitis?

Total duration of antibiotic treatment, following effective debridement surgery, can be limited to 6 weeks for osteomyelitis in the absence of implanted material. When an osteosynthetic device is used or prosthesis retention is attempted, the current guideline advised therapy for 3 to 6 months.

How long does osteomyelitis stay in the hospital?

Because osteomyelitis is often chronic in adults and principally a surgical disease, length of hospital stay is largely influenced by the number of surgical interventions needed and may be well beyond 1 month in resource-rich countries.

What is the most common microorganism that causes osteomyelitis?

The most prevalent microorganism causing osteomyelitis is S. aureus, but the local antibiotic susceptibility pattern of S. aureus may change according to the geographical region.

What infection was removed from the implant?

An implant-related infection due to Staphylococcus aureus was diagnosed, the osteosynthesis material was removed, and the underlying osteomyelitis debrided. The patient received a course of antibiotic treatment with a penicillin-based agent for 3 months.

What is the most common pathogen for osteomyelitis?

Almost every bacterial and fungal pathogen can cause osteomyelitis. Among all bacteria and types of osteomyelitis, except the jaw, S. aureus is the predominant pathogen and accounts for 66 to 75% of reported cases, followed by streptococci and gram-negative pathogens, such as P. aeruginosa.

Can osteomyelitis be amputation?

Amputation is infrequent for long bone osteomyelitis, in contrast to toe osteomyelitis of the diabetic foot. Treatment of infection at the site of a fracture must integrate efforts to achieve fracture healing and treatment of the infection.

What is the surgical management of osteomyelitis?

As with antibiotic therapy, surgical management of long bone osteomyelitis can be guided by the Cierny-Mader classification system. In stage 1, the nidus of infection is limited to the medullary canal and usually caused by blood-borne bacteria or surgical hardware, such as an intermedullary nail.

What is osteomyelitis in long bones?

Osteomyelitis in long bones presents a variety of challenges depending on the infection's particular features (etiology, pathogenesis, extent of bone involvement, and duration) and the patient (infant, child, adult, or immunocompromised).

What are the symptoms of hematogenous osteomyelitis?

Children with hematogenous osteomyelitis may present with acute signs of infection including fever, irritability, lethargy, and local signs of inflammation. However, not all of these signs may be present.

What antibiotics are used for osteomyelitis?

Initial antibiotic therapy for long bone osteomyelitis may consist of either nafcillin or clindamycin (or vancomycin when MRSA, methicillin-resistant Staphylococcus epidermidis, or Enterococcusspp. are suspected) and ciprofloxacin (except with children, where an aminoglycoside should be used).

What is the vascular supply to the bone decreased by osteomyelitis?

In early acute disease, the vascular supply to the bone is decreased by infection extending into the surrounding soft tissue.

What is long bone osteomyelitis?

Long bone osteomyelitis presents a variety of challenges to the physician. The severity of the disease is staged depending upon the infection's particular features, including its etiology, pathogenesis, extent of bone involvement, duration, and host factors particular to the individual patient (infant, child, adult, or immunocompromised).

What are the primary weapons used to treat osteomyelitis?

The primary weapons to treat these infections are culture-specific antibiotics, aggressive debridement, muscle flaps, and bone grafts. This article offers a basic review of the classification, etiology, epidemiology, pathogenesis, and treatment of long bone osteomyelitis.

What is the treatment for osteomyelitis?

Typical treatment when osteomyelitis (bone infection) is discovered is to plan a surgical treatment , usually wide debridement, but up to and including amputation. I was recently treating an 80-year-old with a wound on her foot that was healing very well.

How do you know if you have osteomyelitis?

Do you know when osteomyelitis is present? Some symptoms of osteomyelitis include bone pain, redness and pain at the site of infection, and lower extremity swelling. Other signs of infection may also be present including fever, chills and excessive sweating.

Can osteomyelitis be treated with antibiotics?

It turns out, according to more current thought, that most osteomyelitis can be treated with antibiotics. Over 70% of osteomyelitis cases will resolve with appropriate antibiotic treatment, or can be converted into chronic osteomyelitis. A patient can live with chronic osteomyelitis, especially a patient receiving palliative wound care.

Do you need surgery for osteomyelitis?

Your patients will thank you if they can save their legs and stay functional. So, no, osteomyelitis does not always need surgery, in fact, osteomyelitis should rarely need a knife if appropriate treatment interventions are implemented. About The Author.

Can osteomyelitis be detected with an infrared camera?

We have also been able to detect osteomyelitis using an infrared camera. I would urge everyone to be aware that osteomyelitis can be present where a wound is near bone. It can readily be diagnosed with simple techniques. Then, treatment with antibiotics is preferred as the first course of action.

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