Why are beta-blockers avoided in cocaine?
Beta Blockers should not be used in the treatment of cocaine induced myocardial ischaemia.
How long after cocaine can you use beta-blocker?
The 2014 ACCF/AHA guidelines on unstable angina and non–ST-segment elevation myocardial infarction advise that the use of beta-blockers within 4 to 6 hours after cocaine exposure is controversial, with some evidence for harm.
Can you use labetalol with cocaine?
Labetalol is accepted for use in cocaine- and methamphetamine- associated unstable angina/non-ST-elevation myocardial infarction in a recent American Heart Association/American College of Cardiology guideline, specifically: “Administration of combined alpha- and beta-blocking agents (e.g., labetalol) may be reasonable ...
Which beta-blockers are non selective?
WHAT ARE NAMES OF NONSELECTIVE BETA-BLOCKERS?Betapace.Betapace AF.Blocadren (DSC)Corgard.Hemangeol.Inderal.Inderal LA.Innopran XL.More items...•
What do you give for cocaine intoxication?
Emergency treatment of cocaine-associated high body temperature consists of giving a benzodiazepine and physical cooling. Immediate administration of aspirin is required for patients reporting cocaine-associated chest pain.
Can you use alpha and beta-blockers together?
Sometimes, a beta-blocker is combined with an alpha-blocker. This may be useful for men who have hypertension and an enlarged prostate. The alpha-blocker may help both problems at the same time.
Does propranolol interact with cocaine?
Propranolol may reduce symptoms of autonomic arousal associated with early cocaine abstinence and improve treatment outcome. This trial was an 8-week, double-blind, placebo-controlled trial of propranolol in 108 cocaine dependent subjects.
Is metoprolol safe in cocaine?
The attending physician felt that since the use of cocaine occurred 6 hours prior, it would be safe to give metoprolol as the cocaine had probably been metabolized. A dose of 2.5 mg was administered with no effect on the heart rate.
Which B blockers are Cardioselective?
The cardio-selective beta-blockers include atenolol, betaxolol, bisoprolol, esmolol, acebutolol, metoprolol, and nebivolol.
What are contraindications of beta-blockers?
Traditional contraindications to beta-blockers are peripheral vascular diseases, diabetes mellitus, chronic obstructive pulmonary disease (COPD) and asthma.
What's the difference between selective and non selective beta-blockers?
The non-selective β-blockers offer α-blockade resulting in vasodilation and lower peripheral resistance without changes in cardiac output [27, 37, 38]. In addition, carvedilol reduces cardiac adrenergic activity while β-1 selective agents increase sensitivity to adrenergic activity [11].
Why are non selective beta-blockers contraindicated in patients with asthma?
Asthma and chronic obstructive pulmonary disease (COPD) have been classic contraindications to the use of beta blockers because of their potential for causing bronchospasm.