Full Answer
Can you use any nebulizer with Cayston?
CAYSTON is taken as an inhaled breathing treatment with the lightweight, quiet, and portable ALTERA ® Nebulizer System. Do not use any other nebulizer for your CAYSTON treatment. CAYSTON nebulization time is typically 2-3 minutes,* 3 times a day, at least 4 hours apart.
What is Cayston inhalation used for?
Cayston (aztreonam) is an antibiotic that fights severe or life-threatening infection caused by bacteria. Cayston inhalation is used to improve breathing symptoms in people who have cystic fibrosis and a certain bacteria in their lungs.
Who invented the nebulizer?
The first “powered” nebulizer was invented in France in 1858 by a man named Sales-Girons. He made a device that would atomize medication in liquid form.
How often can you take Cayston inhalation?
Cayston inhalation is usually given 3 times daily for 28 days. Follow your doctor's dosing instructions very carefully. Your doses should be spaced at least 4 hours apart. You may need to use a bronchodilator medication before each dose of Cayston inhalation.
What kind of drug is CAYSTON?
CAYSTON is a prescription antibacterial medicine used to improve breathing symptoms in people with cystic fibrosis (CF) who have a lung infection due to Pseudomonas aeruginosa (Pa).
Does CAYSTON need to be refrigerated?
Misconception: Patients need to refrigerate their CAYSTON at all times. Fact: CAYSTON vials and diluent ampules should be stored in the refrigerator at 2 °C to 8 °C (36 °F to 46 °F) until needed.
How often do you take CAYSTON?
The dosing of CAYSTON is flexible enough to allow you to fit it into your schedule as long as you take it 3 times a day with at least 4 hours in between each dose.
What is the CAYSTON community?
My Cayston Community is a program aimed at promoting adherence and providing helpful support and encouragement to patients. Content lives in the form of articles, videos, and emails from the voices of real people in the CAYSTON community. Tell your patients to visit www.cayston.com/my-cayston-community to enroll.
How do you clean a CAYSTON nebulizer?
0:144:50Cleaning & Disinfecting Your Altera or eFlow Nebulizer - YouTubeYouTubeStart of suggested clipEnd of suggested clipThoroughly rinse each part under warm running tap water for approximately 10 seconds rinse bothMoreThoroughly rinse each part under warm running tap water for approximately 10 seconds rinse both sides of the aerosol head being careful not to touch the metal membrane.
How do you mix CAYSTON?
Mix (reconstitute) CAYSTON with the saline only when ready to take a dose. Take 1 amber vial of CAYSTON and 1 ampule of saline from the carton. Separate the saline ampules by gently pulling apart.
How do you use a CAYSTON nebulizer?
CAYSTON nebulization time is typically 2-3 minutes,* 3 times a day, at least 4 hours apart. One course consists of taking CAYSTON 3 times a day for 28 days, followed by at least 28 days off CAYSTON, as directed by your doctor. See examples of how to best fit CAYSTON in to your day.
What is the clinical indication for the use of aztreonam CAYSTON )?
What is aztreonam (Cayston)? Aztreonam is an antibiotic that fights severe or life-threatening infection caused by bacteria. Aztreonam inhalation is used to improve breathing symptoms in people who have cystic fibrosis and a certain bacteria in their lungs.
How is CAYSTON administered?
CAYSTON is administered by inhalation using an Altera Nebulizer System. CAYSTON should not be administered with any other nebulizer. CAYSTON should not be mixed with any other drugs in the Altera Nebulizer Handset. CAYSTON is not for intravenous or intramuscular administration.
Is cayston FDA approved?
(Nasdaq:GILD) today announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Cayston(R)(aztreonam for inhalation solution) as a treatment to improve respiratory symptoms in cystic fibrosis (CF) patients with Pseudomonas aeruginosa (P. aeruginosa).
Who can take Kalydeco?
Check Your Eligibility. KALYDECO is for people with cystic fibrosis (CF) age 4 months and older with at least one mutation in their CF gene that is responsive to KALYDECO. Enter your mutations to see if at least one of them is eligible.
CAYSTON improved respiratory symptoms and lung function
As shown in the AIR-CF1 Study, people with CF and Pa taking CAYSTON reported an improvement in their breathing symptoms such as wheezing, coughing, and mucus production on Day 28 compared to placebo (a solution with no medication in it). People also had an improvement in lung function.
CAYSTON and Tobramycin Inhalation Solution (TOBI) were studied together
The goal of the Active Comparator Study was to look at 2 approved medications, CAYSTON and TOBI, by tracking changes in FEV 1 in people with CF taking CAYSTON or TOBI over 3 treatment courses.
People experience some common side effects while taking CAYSTON
The most common side effects of CAYSTON include cough, nasal congestion, wheezing, sore throat, fever (may be more common in children than in adults), chest discomfort, stomach area (abdominal) pain, and vomiting. These are not all the possible side effects of CAYSTON. Please see additional Important Safety Information to the right below .
CAYSTON goes where you go
The quiet and portable ALTERA ® Nebulizer System makes it convenient to bring CAYSTON with you on the go (especially if you have a carrying case ).
CAYSTON gives you fast treatment time and flexible dosing
CAYSTON nebulization time is typically 2–3 minutes,* and is taken 3 times a day, at least 4 hours apart over a 28-day course of treatment. See how CAYSTON may fit into your schedule schedule with our interactive dosing tool .
What is a Cayston?
CAYSTON is a prescription antibacterial medicine used to improve breathing symptoms in people with cystic fibrosis (CF) who have a lung infection due to Pseudomonas aeruginosa (Pa). CAYSTON is not for infections caused by other bacteria or viruses, such as the common cold.
What are the side effects of Cayston?
What are the possible side effects of CAYSTON? CAYSTON may cause serious side effects, including: Severe allergic reactions. Stop your treatment with CAYSTON and call your healthcare provider right away if you have any symptoms of an allergic reaction, including rash or swelling of your face, or throat tightness.
Can Cayston harm a baby?
Tell your healthcare provider about all of your medical conditions, including if you are allergic to any antibiotics; if you are pregnant or plan to become pregnant, as it is not known if CAYSTON can harm your unborn baby; if you are breastfeeding or plan to breastfeed, as CAYSTON can pass into your breastmilk.
Is Cayston safe for children?
CAYSTON is not for infections caused by other bacteria or viruses, such as the common cold. It is not known if CAYSTON is safe and effective in children under the age of 7 or in people with FEV 1 <25% or >75% predicted.
Does Cayston cause coughing?
The most common side effects of CAYSTON include cough, nasal congestion, wheezing, sore throat, fever, chest discomfort, stomach area pain, and vomiting. These are not all the possible side effects of CAYSTON. Tell your healthcare provider if you have any new or worsening symptoms while taking CAYSTON and about any side effect ...
PREPARING CAYSTON
See all of the important details you should know while preparing and taking CAYSTON.
Caring for Your ALTERA Nebulizer System
The ALTERA Nebulizer System is small, portable, and battery operated, allowing you to administer your CAYSTON quickly* and quietly throughout the day.
Cleaning and disinfecting
Clean the ALTERA Handset after each dose to help prevent the Aerosol Head from clogging.
When was the nebulizer invented?
The first “powered” nebulizer was invented in France in 1858 by a man named Sales-Girons. He made a device that would atomize medication in liquid form. It was similar to a bicycle pump where you would lift up and push down on a long pump handle which would push the medication through the atomizer and near the persons mouth where they would breathe it in.
What was the first inhaled corticosteroid?
In the 1960s there was a pretty serious epidemic of asthma deaths and these medications were superseded by more selective short acting beta-agonist albuterol and the first inhaled corticosteroid (ICS) beclomethasone. Since that time, MDI’s have made leaps and bounds to what we have today.
What propellants were used in MDIs?
The first MDIs were made with CFC (chlorofluorocarbon) propellant systems and were found to be detrimental to the environment, specifically to the ozone layer. A replacement propellant was developed and CFCs were replaced with HFA (Hydrofluoroalkane). The substitution of HFA propellants changed the make up of the inhalers ...
When was the first spray inhaler invented?
In 1864 in Germany, Dr. Siegel invented the first “spray inhaler ” which used steam from boiling water underneath the device to force the steam across the medication chamber and draw it out of a glass tube that the patient would then breathe in. In the early 1900s many asthma patients would use hand held atomizers.
When did epinephrine become a first line treatment for asthma flare ups?
In the early 1900s many asthma patients would use hand held atomizers. In 1910 epinephrine became a first line treatment for asthma flare ups when it became available in a solution that could be nebulized with less side effects than injecting it directly into a vein. The term “aerosol” was first coined in 1920.
How to inhale asthma smoke?
The directions for inhaling the asthma cigarettes was very similar to both metered dose inhalers (MDI) and dry powder inhalers (DPI) like we have today. Breathe all the way out and then take a deep breath & inhale as much of the smoke in as possible and then hold your breath for several seconds before exhaling.
Multiple handsets can be disinfected all at once at the end of the day
Patients will receive a new ALTERA Nebulizer Handset † with each shipment of CAYSTON. To save time, patients with multiple handsets can use a different one for each of their daily doses, wash them after use, but wait to disinfect them all at once at the end of the day.
Cleaning and Disinfecting
To reduce the risk of infection and ensure proper operation, the ALTERA Nebulizer Handset should be cleaned and dried as soon as possible after each use and disinfected before it’s used again.
Carrying Case for CAYSTON and the ALTERA Nebulizer
Your patients can sign up to receive a carrying case for CAYSTON and the ALTERA Nebulizer System. For US residents only. It may take up to 4-6 weeks to receive the carrying case.
What to do if you have an allergic reaction to Cayston?
If an allergic reaction occurs, stop administration of CAYSTON and initiate treatment as appropriate . Caution is advised when administering CAYSTON to patients if they have a history of allergy to beta-lactam antibiotics, such as penicillins, cephalosporins, and/or carbapenems, since cross-reactivity may occur.
Can you use Cayston for CF?
To reduce the development of drug-resistant bacteria and maintain the effectiveness of CAYSTON and other antibacterial drugs, CAYSTON should be used only to treat patients with CF known to have Pa in the lungs. Please click here to see full Prescribing Information.