Medication
Procedures
Therapy
Self-care
Nutrition
What type of gene therapy is used for sickle cell anemia?
With the new gene therapy, called LentiGlobin, blood-forming stem cells are collected from the patient's blood. Harmless lentiviruses are then used to deliver a modified copy of the beta-globin gene into the stem cells.
What is the mainstay of treatment in sickle cell syndromes?
Since publication of its landmark trial in 1995, hydroxyurea continues to represent a mainstay of disease-modifying therapy for SCD. Hydroxyurea induces fetal hemoglobin production through stress erythropoiesis, reduces inflammation, increases nitric oxide and decreases cell adhesion.
What is the best medication for sickle cell?
Approved Treatments for Sickle Cell DiseaseAdakveo. Adakveo (crizanluzumab) is administered as an injection into the bloodstream to treat painful vaso-occlusive crisis events caused by sickle cell disease. ... Endari. ... Hydroxyurea. ... Ketamine. ... NSAIDs. ... Oxbryta. ... Opioid Narcotics.
How do you treat a child with sickle cell anemia?
To help your child manage sickle cell disease:Go to all doctor's visits and share any concerns or new symptoms.Make sure your child takes all prescribed medicines.Follow up with any recommended specialists to check for complications.Help your child avoid pain crisis triggers, such as extreme temperatures or stress.More items...
Diagnosis
Lifestyle and Home Remedies
Coping and Support
Preparing For Your Appointment
Specialist to consult
Blood, Stem Cell, and Bone Marrow Transplants
- A blood test can check for the form of hemoglobin that underlies sickle cell anemia. In the United States, this blood test is part of routine newborn screening. But older children and adults can be tested, too. In adults, a blood sample is drawn from a vein in the arm. In young children and babi…
Hydroxyurea
- Taking the following steps to stay healthy might help you avoid complications of sickle cell anemia: 1. Take folic acid supplements daily and choose a healthy diet.Bone marrow needs folic acid and other vitamins to make new red blood cells. Ask your doctor about a folic acid supplement and other vitamins. Eat a variety of colorful fruits and vegetables, as well as whole g…
SCD Complications
- If you or someone in your family has sickle cell anemia, you might consider the following to help you cope: 1. Finding someone to talk with.Living with a chronic illness is stressful. Consider consulting a mental health professional, such as a psychologist, counselor or social worker, to help you cope. 2. Join a support group.Ask your health care provider about support groups for fa…
Gene Therapy & Novel Treatment Strategies
- Sickle cell anemia is usually diagnosed through genetic screening done when a baby is born. Those test results will likely be given to your family doctor or pediatrician. He or she will likely refer you to a doctor who specializes in blood disorders (hematologist) or a pediatric hematologist. Here's information to help you get ready for your appointment.
References
Further Reading
- Hydroxyurea (HU) is an effective medication that can reduce the frequency of painful episodes and clotting in SCD. HU can induce fetal hemoglobin (HbF) production in favor of faulty sickle hemoglobin (HbS) as well as reducing HbS polymerization. Hydroxyurea is also able to reduce the expression of clot-inducing adhesion molecules in red blood cells, as well as leading to a reducti…