Which medication is contraindicated during pregnancy?
Some of the over-the-counter medicines that increase the chances of birth defects are: Bismuth subsalicylate (such as Pepto-Bismol). Phenylephrine or pseudoephedrine, which are decongestants. Avoid medicines with these ingredients during the first trimester.
What treatments can not be used during pregnancy?
Medications You Should Avoid During PregnancyChloramphenicol.Cipro and levofloxacin.Primaquine.Sulfonamides.Trimethoprim (Primsol)Codeine.Ibuprofen (Advil, Motrin)Warfarin (Coumadin)More items...•
Which drug is contraindicated during pregnancy due to its teratogenicity?
Teratogenic drugs and birth defects isotretinoin (an acne drug) alcohol. cocaine. high doses of vitamin A.
Is ceftriaxone contraindicated in pregnancy?
The U.S. Food and Drug Administration (FDA) considers ceftriaxone a pregnancy Category B medicine, which means that it has not been studied in pregnant women. However, when studied in pregnant animals, ceftriaxone showed no negative effects on unborn babies.
Depression
Management of Depression During Pregnancy: A Report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists Obstet Gynecol. 2009; 114: 703-713 Yonkers KA, Wisner KL, Stewart DE; et. al. [ Read guidelines external icon ]
Epilepsy
Practice Parameter update: Management issues for women with epilepsy—Focus on pregnancy (an evidence based review): Teratogenesis and perinatal outcomes Neurology. 2009; 73: 133-141. Harden CL, Meador KJ, Pennell PB, et al. [ Read recommendations pdf icon external icon ]
Nausea and Vomiting
ACOG Practice Bulletin No. 189: Nausea and Vomiting Of Pregnancy Obstet Gynecol. 2018;131:15-30. [Read recommendations] external icon
Pain
Clinical Guidance for Treating Pregnant and Parenting Women With Opioid Use Disorder and Their Infants SAMHSA. 2018; HHS Publication No. (SMA) 18-5054 [ Read guidelines external icon ]
Additional Resources
Many organizations are committed to understanding more about medicines and pregnancy and providing helpful resources for women and healthcare providers.
Can you take ACE inhibitors while pregnant?
Answer. ACE inhibitors should be avoided during pregnancy, as they are associated with fetal renal dysgenesis or death when used in the second and third trimesters, as well as with increased risk of cardiovascular and central nervous system malformations when used in the first trimester. [ 24] . In a retrospective cohort study, Li et al found ...
Can you take angiotensin II during pregnancy?
Angiotensin II receptor antagonists/blockers are not used during pregnancy, because they have a mechanism of action that is similar to that of ACE inhibitors. Diuretics do not cause fetal malformations but are generally avoided in pregnancy, as they prevent the physiologic volume expansion seen in normal pregnancy.
Can ACE inhibitors cause malformations?
In a retrospective cohort study, Li et al found that during the first trimester, the risk of malformations with the use of ACE inhibitors is similar to the use of other antihypertensives but that the apparent increased risk of malformations is due more to the mother’s underlying hypertension rather than the medications. [ 25]
What is the CDC's guidance for post delivery management of infants born to mothers with known or suspected SARS
Specific guidance for post-delivery management of infants born to mothers with known or suspected SARS-CoV-2 infection , including breastfeeding recommendations, is provided by the CDC 14,15 and the American Academy of Pediatrics. 16
Is nausea more common in pregnant people than nonpregnant people?
Local injection site pain, nausea, and vomiting were reported slightly more frequently in pregnant people than in nonpregnant people. Other systemic reactions were reported more frequently among nonpregnant vaccine recipients, but the overall reactogenicity profile was similar for pregnant and nonpregnant patients.
What is the best treatment for influenza during pregnancy?
The Centers for Disease Control and Prevention (CDC) recommends women in any trimester of their pregnancy who have a suspected or confirmed influenza infection receive prompt antiviral therapy with Tamiflu (oseltamavir) or Relenza (zanamivir).
What does "pregnancy category C" mean?
Both drugs are designated "Pregnancy Category C," which means that they have not been studied in pregnant women. However, Pregnancy Category C does NOT mean the drug cannot be used in pregnant women. Pregnant women can and should receive a category C drug when the possible benefits of using the drug are more likely than the possible risk ...
Is antiviral therapy safe for pregnant women?
The CDC has looked at these issues carefully for pregnant women: because the risks of influenza for pregnant women are serious, CDC believes that the benefits of antiviral therapy outweigh the potential for risks from the drugs. Both drugs are designated "Pregnancy Category C," which means that they have not been studied in pregnant women.
What are contraindications for abortion?
Definitions. Contraindications: If a woman has any of these specific conditions, she should not be offered medical abortion with the specified regimen. Vacuum aspiration, dilatation and evacuation or treatment for ectopic pregnancy should be offered, as appropriate. Precautions: If a woman has any of these specific conditions, ...
Is medical abortion risky?
Precautions: If a woman has any of these specific conditions, medical abortion with the specified regimen may incur higher risks than normal. The risks, benefits and alternatives to medical abortion must be considered. Medical abortion provision to women with these conditions may require a higher degree of clinical judgment, skill and monitoring.
Can you give asthmatic women mifepristone?
Medical abortion in asthmatic women requiring systemic corticosteroids has not been studied as giving mifepristone to such women risks asthma exacerbation. One review suggests using a high level of caution when giving mifepristone to such women and only doing so if the asthma is well-controlled (Davey, 2006).
Is an IUD in place?
Precautions. IUD in place: A woman who is pregnant with an IUD is at significantly elevated risk of ectopic pregnancy ( Barnhart, 2009) and must be evaluated for the presence of ectopic pregnancy. If the pregnancy is found to be intrauterine, the IUD should be removed before starting medical abortion due to the theoretical risk ...
Why are beta blockers used during pregnancy?
Beta-blockers are used frequently for the treatment of several cardiovascular conditions during pregnancy. Large, retrospective studies show no association between the use of beta-blockers and major congenital abnormalities. Beta-blockers are associated with intrauterine growth restriction (small for gestational age infants), ...
When should antiarrhythmics be avoided?
Antiarrhythmic medications should be avoided in the first trimester if possible, and the lowest effective dose should be used. Amiodarone should be avoided due to the risk of fetal thyroid and neurodevelopmental complications.
What is the best treatment for SVT?
Beta-blockers (with or without digoxin) or oral verapamil can be used for suppressive therapy for SVT in the absence of pre-excitation. Sotalol or flecainide can be considered in the absence of structural heart abnormalities. In Wolff-Parkinson-White (WPW) syndrome, fle cainide or propafenone are recommended for the prevention of SVT.
Can digoxin be used for pulmonary edema?
Beta-blockers can be used, and digoxin can be considered. Diuretics (furosemide, bumetanide, hydrochlorothiazide) can be used for pulmonary edema, but excessive dosing carries the risk of placental hypoperfusion and fetal electrolyte abnormalities.
Can you give LMWH after 24 hours?
Regional anesthesia cannot be given within 24 hours of the last dose of LMWH. Cesarean delivery should be performed if a mother arrives in labor while on warfarin. Reversal of warfarin with vitamin K in the mother does not ensure reversal in the fetus.
Can prostaglandins be used for pulmonary arterial hypertension?
Pulmonary Arterial Hypertension. Parenteral and inhaled prostaglandins can be used in the appropriate setting and phosphodiesterase-5 inhibitors may be considered. Endothelin receptor blockers (bosentan, ambrisentan, macitentan) are teratogenic and should not be used.
Is aspirin safe during pregnancy?
Low-dose aspirin is considered safe during pregnancy and lactation, and is commonly used for the prevention of pre-eclampsia. High-dose aspirin should be avoided due to the risk of premature closure of the ductus arteriosus. Clopidogrel has been used in pregnancy but since there are limited data, it is recommended to use it for ...
