Trichomoniasis can be cured with a single dose of prescription antibiotic medication (either metronidazole or tinidazole), pills which can be taken by mouth.
What are the drugs of choice for trichomoniasis?
The nitroimidazoles are the only class of antimicrobials known to be effective against trichomonas infection. Metronidazole resistance occurs in 4%–10% of cases of vaginal trichomoniasis ( 1116, 1118 ). Tinidazole resistance is less well studied but was present in 1% of infections in one study ( 1116 ).
Is metronidazole effective for trichomoniasis?
Jul 12, 2020 · 5. Which of the following medications is the treatment of choice for trichomonas? a.Metronidazole b.Ceftriaxone c.Diflucan d.Doxycycline ____ 6. …
What is included in patient education about trichomoniasis during pregnancy?
Nov 17, 2021 · The drugs of choice for trichomoniasis are the nitroimidazole antibiotics metronidazole and tinidazole. The optimal choice will depend on the patient’s allergies to these drugs, the organism’s drug resistance, the presence …
What is expedited partner therapy for trichomoniasis?
Jan 13, 2022 · The following treatment options are recommended by the CDC: Single-dose 2-g oral metronidazole therapy Prolonged metronidazole therapy with 500 mg twice daily for 7 days Single-dose 2-g oral...
Drugs used to treat Trichomoniasis
The following list of medications are in some way related to, or used in the treatment of this condition.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Other Management Considerations
Providers should advise persons with T. vaginalis infections to abstain from sex until they and their sex partners are treated (i.e., when therapy has been completed and any symptoms have resolved). Testing for other STIs, including HIV, syphilis, gonorrhea, and chlamydia, should be performed for persons with T. vaginalis.
Follow-Up
Because of the high rate of reinfection among women treated for trichomoniasis, retesting for T. vaginalis is recommended for all sexually active women approximately 3 months after initial treatment regardless of whether they believe their sex partners were treated ( 137, 1115 ).
Management of Sex Partners
Concurrent treatment of all sex partners is vital for preventing reinfections. Current partners should be referred for presumptive therapy. Partners also should be advised to abstain from intercourse until they and their sex partners have been treated and any symptoms have resolved.
Recurrent Trichomoniasis
A recurrent infection can result from treatment failure (antimicrobial-resistant T. vaginalis or host-related problems), lack of adherence, or reinfection from an untreated sex partner. In the case of a recurrent infection, the origin of the repeat infection should be assessed because most recurrent infections likely result from reinfection.
Special Considerations
Metronidazole and tinidazole are both nitroimidazoles. Patients with an IgE-mediated-type hypersensitivity reaction to 5-nitroimidazole antimicrobials should be managed by metronidazole desensitization according to published regimens ( 1127, 1128) and in consultation with an allergy specialist. The optimal treatment for patients with T.
Treatment
Treatment reduces symptoms and signs of T. vaginalis infection, cures infection, and might reduce transmission. Likelihood of adverse outcomes among women with HIV infection is also reduced with T. vaginalis therapy.
What is the best medication for trichomoniasis?
The drugs of choice for trichomoniasis are the nitroimidazole antibiotics metronidazole and tinidazole. The optimal choice will depend on the patient’s allergies to these drugs, the organism’s drug resistance, the presence of HIV infection, and the persistence of the infection. Best Medications for Trichomoniasis.
What is the cause of trichomoniasis?
Infecting both and women, trichomoniasis is caused by a parasite, Trichomonas vaginalis (or T. vaginalis), that colonizes the vagina, urethra, and prostate gland. 95% of infections are readily cured by a single large dose of the antibiotic metronidazole. Trichomonas vaginalis is a protozoan: a one-celled organism.
How long does it take to clear trichomoniasis?
95% of T. vaginalis infections are successfully cleared by metronidazole or tinidazole treatment. The Centers for Disease Control (CDC) recommends that patients treated for trichomoniasis be seen within three months for a test-of-cure follow-up visit. Most clinics and healthcare professionals will schedule this visit two to three weeks after treatment. A NAAT test will be performed on a vaginal or urethral sample to confirm the infection has cleared.
How long does it take to get trichomoniasis results?
These tests can be purchased as trichomoniasis-only tests or as multiple-STD tests. Results will take two to four days to receive. The cost of the lab test is usually included in the cost of the kit.
How long does metronidazole help with trichomonasis?
HIV patients, however, will be given a twice-daily 500 mg dose of metronidazole for seven days.
What are the risk factors for trichomoniasis?
T. vaginalis infections are most common in people who have multiple sexual partners. Other risk factors include new sexual partners, unprotected sex, or a history of STD infections.
Can trichomoniasis cause low birth weight?
However, left untreated, trichomoniasis can cause problems in pregnant women—premature membrane rupture, premature birth, and low birth weight. Also, trichomoniasis makes both men and women more susceptible to pelvic inflammatory disease and STDs such as HIV/AIDs, syphilis, and gonorrhea.
How much metronidazole should I take for trichomoniasis?
The CDC does not offer a definitive recommendation on treating pregnant patients with symptomatic trichomoniasis but currently recommends that a single 2-g dose of metronidazole be used when treatment is prescribed. [ 11] . Infected asymptomatic pregnant women may wish to defer treatment to after 37 weeks’ gestation. [ 48] .
How long does metronidazole last?
The following treatment options are recommended by the CDC: Prolonged metronidazole therapy with 500 mg twice daily for 7 days. Single-dose tinidazole or metronidazole appears to be equally effective in the treatment of trichomoniasis.
Where do T vaginalis trophozoite reside?
Life cycle of Trichomonas vaginalis. T vaginalis trophozoite resides in female lower genital tract and in male urethra and prostate (1), where it replicates by binary fission (2).
Is metronidazole teratogenic?
Topical treatments are not recommended due to inadequate therapeutic levels. [ 11] . Treatment with oral metronidazole has not been shown to have teratogenic effects [ 122, 123] and may prevent transmission to the infant.
Can pregnant women take tinidazole?
Tinidazole is a pregnancy Class C agent and should not be used by pregnant women. Drug-resistance in T vaginalis infection is rare, despite the prevalent use of nitroimidazole drugs. Treatment failures may require a higher-dose regimen, a longer course of the agent, or the use of different nitroimidazoles.
Is tinidazole more expensive than metronidazole?
Tinidazole is generally more expensive than metronidazole but may have fewer side-effects and remains in serum longer. Single-dose therapy with metronidazole or tinidazole improves patient compliance and results in a lower total dose than the week-long metronidazole schedule, although the week-long schedule may be useful in some situations, ...
