Can trichomoniasis be cured?
The nitroimidazoles are the only class of antimicrobials known to be effective against trichomonas infection. Metronidazole resistance occurs in 4%–10% of cases of vaginal trichomoniasis ( 1116, 1118 ). Tinidazole resistance is less well studied but was present in 1% of infections in one study ( 1116 ).
Are nitroimidazoles effective against trichomonas infection?
Oct 01, 2001 · Nitroimidazoles (such as metronidazole [Flagyl]) are the most effective treatment for parasitological cure of trichomoniasis. Single-dose treatment is …
When is trichomoniasis retesting recommended?
Apr 05, 2022 · As one of most common forms of treatment for trichomoniasis, antibiotics are also one of the most effective. Often, metronidazole and tinidazole are prescribed for the treatments of trichomoniasis, though other antibiotics may be prescribed in certain cases. Unlike other types of antibiotics, which are often prescribed for an extended period of time, …
Should pregnant women with trichomoniasis be screened for T. vaginalis?
Nitroimidazoles are the most effective treatment for Trichomonal vaginalis. • The BNF recommends metronidazole by mouth in children with urogenital trichomonasis as follows: Child 1-2 years: 50 mg 3 times a day for 7 days.
Other Management Considerations
Providers should advise persons with T. vaginalis infections to abstain from sex until they and their sex partners are treated (i.e., when therapy has been completed and any symptoms have resolved). Testing for other STIs, including HIV, syphilis, gonorrhea, and chlamydia, should be performed for persons with T. vaginalis.
Follow-Up
Because of the high rate of reinfection among women treated for trichomoniasis, retesting for T. vaginalis is recommended for all sexually active women approximately 3 months after initial treatment regardless of whether they believe their sex partners were treated ( 137, 1115 ).
Management of Sex Partners
Concurrent treatment of all sex partners is vital for preventing reinfections. Current partners should be referred for presumptive therapy. Partners also should be advised to abstain from intercourse until they and their sex partners have been treated and any symptoms have resolved.
Recurrent Trichomoniasis
A recurrent infection can result from treatment failure (antimicrobial-resistant T. vaginalis or host-related problems), lack of adherence, or reinfection from an untreated sex partner. In the case of a recurrent infection, the origin of the repeat infection should be assessed because most recurrent infections likely result from reinfection.
Special Considerations
Metronidazole and tinidazole are both nitroimidazoles. Patients with an IgE-mediated-type hypersensitivity reaction to 5-nitroimidazole antimicrobials should be managed by metronidazole desensitization according to published regimens ( 1127, 1128) and in consultation with an allergy specialist. The optimal treatment for patients with T.
Treatment
Treatment reduces symptoms and signs of T. vaginalis infection, cures infection, and might reduce transmission. Likelihood of adverse outcomes among women with HIV infection is also reduced with T. vaginalis therapy.
Clinical Scenario
A 26-year-old woman presents with a yellow vaginal discharge, vaginal itching and soreness, and mild dyspareunia. No cervicitis is found but, on wet mount, numerous motile protozoa consistent with Trichomonas vaginalis are seen.
Clinical Question
What is the most effective treatment strategy for women diagnosed with vaginal trichomoniasis?
Evidence-Based Answer
Nitroimidazoles (such as metronidazole [Flagyl]) are the most effective treatment for parasitological cure of trichomoniasis. Single-dose treatment is as effective as longer term treatment but increases side effects.
Practice Pointers
In women with trichomoniasis, physicians can treat both the patient and her partner with a single dose of metronidazole (e.g., one 2-g oral dose) in return for a 90 percent chance of parasitological cure in one month.
Drugs used to treat Trichomoniasis
The following list of medications are in some way related to, or used in the treatment of this condition.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
What is a client with type 1 diabetes mellitus receiving?
A client with type 1 diabetes mellitus is receiving short-acting insulin to maintain control of blood glucose levels. In providing glucometer instructions, the nurse would instruct the client to use which site for most accurate findings?
What is a chlamydial infection?
Chlamydial infection. 1. A patient has been admitted to a medical unit with respiratory symptoms that are characteristic of tuberculosis. When transporting the patient to radiology for a chest x-ray, the nurse has applied a mask that covers the patient's nose and mouth.
Why do ketones accumulate in urine?
As cells rupture, they release these acids into the blood.". "Ketones accumulate in the blood and urine when fat breaks down in the absence of insulin. Ketones signal an insulin deficiency that will cause the body to start breaking down stored fat for energy.".
Why use a spirometer?
Use of an incentive spirometer helps to prevent pneumonia and atelectasis.) The nurse is creating a plan of care for a client scheduled for surgery. The nurse should include which activity in the nursing care plan for the client on the day of surgery? 1.
What is a nurse practitioner?
2. A nurse practitioner assessed a patient's complaints about a vaginal discharge and prescribed Flagyl. The nurse was able to diagnose bacterial vaginosis because of this defining characteristic, a discharge that: Is yellow-green and frothy.
Is diabetes more common in blacks than whites?
Diabetes mellitus is more common in Hispanics and Blacks than in Whites. 4. A client with long-standing type 1 diabetes is admitted to the hospital with unstable angina pectoris. After the client's condition stabilizes, the nurse evaluates the diabetes management regimen.
What is the best treatment for trichomoniasis?
As one of most common forms of treatment for trichomoniasis, antibiotics are also one of the most effective. Often, metronidazole and tinidazole are prescribed for the treatments of trichomoniasis, though other antibiotics may be prescribed in certain cases.
Is trichomoniasis a serious disease?
While trichomoniasis can, obviously, be a very serious condition, treatments for trichomoniasis are usually relatively painless.
What is a trichomonas vaginalis?
E. Vaginal secretions 50 Trichomonas vaginalis, an odd-looking protozoan, moves as a whip-like, almost darting motion. Trichomonasis, a bothersome vaginal infection, can be diagnosed by observing this organism in a wet mount of vaginal secretions. It may be washed out in the urine as well.
What are the symptoms of a protozoan infection?
Typical signs and symptoms include a malodorous, green-yellow, frothy discharge, burning, pruritus, dysuria, frequency, dyspareunia, and punctate hemorrhages on the vagina/cervix. Metronidazole is the treatment for this infection.
What percentage of women have vaginal discharge?
Women usually present with vaginal discharge (70%) or frothy yellowish vaginal discharge (<30%), vulval itching and dysuria (urethral infection is seen in 90% of cases). Some women may present with lower abdominal pain and a few others may show signs of vaginitis and vulvitis. However, 50% of women may be asymptomatic.
Where is T. vaginalis found?
The parasite inhabits predominately the female lower genital tract and can also be found in the male urethra and prostate. The parasite divided by binary fission and does not have a cyst form and is transmitted human to human primarily by sexual intercourse. T. vaginalis infection in women is frequently symptomatic.
What is a flagellated protozoan?
Trichomonas vaginalis is a flagellated protozoan which is best diagnosed when a swab is used to sample the fluid in the posterior fornix of the vagina and examined on a slide using a microscope as a "wet prep". Women typically present with a malodorous "frothy" discharge.
What are the symptoms of bacterial vaginosis?
The symptoms include a moderate amount of malodorous ("fishy"), white to gray, homogeneous vaginal discharge.
What is the pH of Candida?
Candida typically causes a thick, white ("cottage-cheese") discharge with a pH of 4 to 5. Also, microscopic examination demonstrates the organism T. vaginalis and not the pseudohyphae seen with a Candida infection. Gardnerella vaginalis (choice B) is a common organism in bacterial vaginosis, in .