Because the use of thiazide diuretics is supported by a strong body of evidence and no other class of antihypertensive medications has been shown to be better at improving outcomes, they are the first-line drugs for most patients with hypertension. Current evidence does not support using beta blockers as first-line therapy for hypertension.
When are different antihypertensive drug classes used as the first‐line drug?
Secondary objectives: when different antihypertensive drug classes are used as the first‐line drug, to quantify the blood pressure lowering effect and the rate of withdrawal due to adverse drug effects, compared to placebo or no treatment. Search methods
What is the initial first-line therapy for Stage 1 hypertension (high blood pressure)?
Initial first-line therapy for stage 1 hypertension includes thiazide diuretics, CCBs, and ACE inhibitors or ARBs. Two first-line drugs of different classes are recommended with stage 2 hypertension and average BP of 20/10 mm Hg above the BP target.
What is the best first‐line treatment for high blood pressure?
Most of the available evidence justifying treatment of patients with elevated blood pressure used a thiazide as the first‐line drug. First‐line low‐dose thiazides were more effective than first‐line high‐dose thiazides and first‐line beta‐blockers.
Which drug class is the best first choice for hypertension?
Thiazides best first choice for hypertension Review Question(s) In this first update of a review published in 2009, we wanted to determine which drug class was the best first‐line choice in treating adult patients with raised blood pressure.
What is the best treatment for hypertension?
Here's what you can do:Eat healthy foods. Eat a heart-healthy diet. ... Decrease the salt in your diet. Aim to limit sodium to less than 2,300 milligrams (mg) a day or less. ... Maintain a healthy weight. ... Increase physical activity. ... Limit alcohol. ... Don't smoke. ... Manage stress. ... Monitor your blood pressure at home.More items...•
What is the drug of choice for hypertension?
Angiotensin converting enzyme inhibitors (ACEIs) are the treatment of choice in patients with hypertension, chronic kidney disease, and proteinuria.
Is Amlodipine first line treatment for hypertension?
Results Amlodipine has good efficacy and safety, in addition to strong evidence from large randomised controlled trials for cardiovascular event reduction. Conclusions Amlodipine should be considered a first-line antihypertensive agent.
What is first line drug?
a drug that is the first choice for treating a particular condition because it is considered a very effective treatment for that condition with the least likelihood of causing side effects. A first-line medication may be a class of drugs (e.g., SSRIs for depression) as well as a single drug.
Which are the drugs for 1st line treatment of hypertension Mcq?
Treatment was to be clearly defined as a specific class of first‐line antihypertensive therapy in one of the following classes: thiazide diuretics, beta blockers, calcium channel blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists, or alpha adrenergic blockers.
Is lisinopril first line for hypertension?
Despite these limitations, both classes are recommended as first-line treatment choices, and ACE inhibitors continue to be far more commonly prescribed in the treatment of hypertension than ARBs, with lisinopril being the most commonly used antihypertensive medication worldwide.
Why are beta-blockers not first line for hypertension?
In summary, beta-blockers are effective in preventing cardiovascular disease but are no longer suitable for routine initial treatment of hypertension because their cardiovascular protection and metabolic effects are worse than those of other antihypertensive drugs.
Which are the drugs for 2nd line treatment of hypertension?
SubstancesAdrenergic beta-Antagonists.Angiotensin II Type 1 Receptor Blockers.Antihypertensive Agents.Calcium Channel Blockers.Diuretics.Sodium Chloride Symporter Inhibitors.