Treatment FAQ

which of the following drugs is the most potent treatment for gerd

by Dr. Emil Kunde Published 3 years ago Updated 2 years ago

PPIs: PPIs are the most effective medical therapy to treat GERD . PPIs work by blocking the mechanism that produces stomach acid.

Medication

76 rows · Topics under GERD. Barrett's Esophagus (16 drugs) Laryngopharyngeal Reflux (6 drugs) Alternative treatments for GERD. The following products are considered to be alternative treatments or natural remedies for GERD. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above.

Procedures

Nexium ( esomeprazole) is used to treat gastroesophageal reflux disease ( GERD ), ulcers, certain bacteria in the stomach, and inflammation of the esophagus. It can also be used to prevent ulcers in patients taking medicines called NSAIDs. Esomeprazole is more popular than other proton pump inhibitors.

Nutrition

Prokinetic agents are drugs that enhance the activity of the smooth muscle of your gastrointestinal tract. These drugs are somewhat less effective than PPIs. Your doctor may prescribe them in combination with an acid-suppressing drug. TIF and Other Endoscopic Therapy. Transoral incisionless fundoplication (TIF) is an option to address GERD.

What is the strongest medication for GERD?

Mar 29, 2022 · PPIs are the most powerful medications available for treating GERD. These agents should be used only when this condition has been objectively documented. They have few adverse effects.

What is the best treatment of Gerd?

PPIs lower the amount of acid your stomach makes. PPIs are better at treating GERD symptoms than H2 blockers, and they can heal the esophageal lining in most people with GERD. You can buy PPIs over the counter, or your doctor can prescribe one. Doctors may prescribe PPIs for long-term GERD treatment.

Are there any medications that can make Gerd worse?

May 07, 2021 · Histamine blockers (H2 blockers or H2-receptor antagonists) are another class of medications used to treat GERD. H2 blockers, similar to PPIs, block signals from certain cells in the stomach that promote the production of stomach acid. This process reduces acid overall and may help reduce the symptoms of GERD.

What to eat to improve Gerd?

Jun 26, 2013 · Acid suppression is the mainstay of therapy for GERD and proton pump inhibitors (PPIs) are the most potent drug in this regard. Although the use of PPIs is the treatment of choice for GERD, still approximately one-third of patients with GERD fail to response symptomatically to a standard dose PPI, either partially or completely [14, 15]. Refractory GERD, defined as reflux …

What is the most potent therapy for the prevention of GERD?

PPIs are accepted as the most effective treatment for GERD and are the mainstay of initial GERD management, providing more rapid symptom control and better healing of erosive esophagitis than H2-receptor antagonists and antacids.

What is the first line treatment for GERD?

Lifestyle modifications and acid-suppressive therapy through the use of antacids, H2RAs, or PPIs remain first-line treatment options for the management of GERD despite limited supporting data.Dec 16, 2016

What treatment is used for GERD?

Your doctor may prescribe one or more medicines to treat GERD.
  • Antacids. Doctors may recommend antacids to relieve mild heartburn and other mild GER and GERD symptoms. ...
  • H2 blockers. ...
  • Proton pump inhibitors (PPIs). ...
  • Other medicines. ...
  • Fundoplication. ...
  • Bariatric surgery. ...
  • Endoscopy.

What is the medicine of GERD?

These include esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), rabeprazole (Aciphex) and dexlansoprazole (Dexilant).May 22, 2020

What is the best medicine for GERD?

Prevacid (lansoprazole) Lansoprazole (Prevacid) is a moderately priced drug used to treat GERD, heartburn, gastric ulcer, and duodenal ulcer. It works by reducing acid in the stomach. It is slightly more popular than comparable drugs.

What is the name of the drug that is used to treat gastroesophageal reflux disease?

Protonix (pantoprazole) Pantoprazole (Protonix) is an inexpensive drug used to treat gastroesophageal reflux disease, inflammation of the esophagus, and Zollinger-Ellison syndrome. This drug is slightly more popular than comparable drugs. It is available in brand and generic form.

What is Prilosec used for?

Prilosec (omeprazole) Omeprazole (Prilosec) is an inexpensive drug used to treat certain conditions where there is too much acid in the stomach, like ulcers and gastroesophageal reflux disease ( GERD ). It is more popular than comparable drugs.

Is omeprazole a prescription drug?

Omeprazole (Prilosec) is an inexpensive drug used to treat certain conditions where there is too much acid in the stomach, like ulcers and gastroesophageal reflux disease ( GERD ). It is more popular than comparable drugs. It is available in both generic and brand versions, and without a prescription. Generic omeprazole is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

What is the class of famotidine?

Pepcid (famotidine) Drug class: Histamine-2 Antagonists. Famotidine (Pepcid) is a type of antihistamine that blocks the release of stomach acid. It is used to treat stomach or intestinal ulcers. It can also relieve heartburn from acid reflux. It is more popular than comparable drugs.

Is famotidine a generic?

It can also relieve heartburn from acid reflux. It is more popular than comparable drugs. It is available in generic and brand versions.Generic famotidine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Is lansoprazole a Medicare drug?

It is slightly more popular than comparable drugs. It is available in generic and brand versions. Generic lansoprazole is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

What is the best medicine for reflux?

Antacids. Over-the-counter antacids are best for intermittent and relatively infrequent symptoms of reflux. When taken frequently, antacids may worsen the problem. They leave the stomach quickly, and your stomach actually increases acid production as a result.

How to treat GERD?

Dietary and lifestyle changes are the first step in treating GERD. Certain foods make the reflux worse. Suggestions to help alleviate symptoms include: 1 Lose weight if you are overweight — of all of the lifestyle changes you can make, this one is the most effective. 2 Avoid foods that increase the level of acid in your stomach, including caffeinated beverages. 3 Avoid foods that decrease the pressure in the lower esophagus, such as fatty foods, alcohol and peppermint. 4 Avoid foods that affect peristalsis (the muscle movements in your digestive tract), such as coffee, alcohol and acidic liquids. 5 Avoid foods that slow gastric emptying, including fatty foods. 6 Avoid large meals. 7 Quit smoking. 8 Do not lie down immediately after a meal. 9 Elevate the level of your head when you lie down.

What is a prokinetic agent?

Prokinetic agents are drugs that enhance the activity of the smooth muscle of your gastrointestinal tract. These drugs are somewhat less effective than PPIs. Your doctor may prescribe them in combination with an acid-suppressing drug.

What is a TIF for GERD?

Transoral incisionless fundo plication (TIF) is an option to address GERD. TIF can mean a shorter treatment time, less pain and faster recovery compared to laparoscopic surgery. The procedure involves using a special TIF device to create a passageway for a flexible, tube-like imaging instrument called an endoscope. The procedure allows the physician to use preloaded tweezers and fasteners to repair or recreate the valve that serves as a natural barrier to reflux.#N#Currently, there are clinical trials testing the efficacy of endoscopic therapy for GERD. One form of therapy uses an endoscopic sewing machine to place sutures in the stomach and increase the anti-reflux barrier.

Can you have surgery for GERD?

Surgery for GERD. If your symptoms did not improve with lifestyle changes or drug therapy, you may be a candidate for surgery. Some patients prefer a surgical approach as an alternative to a lifetime of taking medications. The goal of surgery for reflux disease is to strengthen the anti-reflux barrier.

What is the procedure to treat reflux disease?

The goal of surgery for reflux disease is to strengthen the anti-reflux barrier.#N#During a procedure known as a Nissen fundoplication, your surgeon wraps the upper part of your stomach around the lower esophagus. This enhances the anti-reflux barrier and can provide permanent relief from reflux. Your surgeon may perform this surgery laparoscopically, which means a less invasive procedure with a shorter recovery time.

Can reflux cause pneumonia?

It may also cause bronchitis, asthma or pneumonia. If there are no obvious causes for the inflammation, your doctor may suspect reflux. The goal of treatment is to improve the symptoms through medication.

What is the best medication for GERD?

pantoprazole sodium (Protonix) rabeprazole sodium (Aciphex) Another prescription drug known as Vimovo is also available for treating GERD. It contains a combination of esomeprazole and naproxen. Prescription-strength and over-the-counter PPIs seem to work equally well in preventing GERD symptoms.

Can PPIs help with GERD?

Prescription-strength and over-the-counter PPIs seem to work equally well in preventing GERD symptoms. Talk to your doctor if GERD symptoms don’t improve with over-the-counter or prescription PPIs within a few weeks. You could possibly have a Helicobacter pylori ( H. pylori) bacterial infection.

How to tell if you have GERD?

Talk to your doctor if GERD symptoms don’t improve with over-the-counter or prescription PPIs within a few weeks. You could possibly have a Helicobacter pylori ( H. pylori) bacterial infection. This type of infection requires more complex treatment. However, the infection doesn’t always cause symptoms. When symptoms do develop, they’re very similar to GERD symptoms. This makes it hard to distinguish between the two conditions. Symptoms of an H. pylori infection may include: 1 nausea 2 frequent burping 3 loss of appetite 4 bloating

What are the stages of GERD?

The first two stages include taking medications and making diet and lifestyle changes . The third stage is surgery. Surgery is generally used only as a last resort in very severe cases of GERD that involve complications. Most people will benefit from first-stage treatments by adjusting how, when, and what they eat.

How long does it take for a PPI to work?

PPIs help to decrease stomach acid over a four to 12-week period. This amount of time allows for proper healing of the esophageal tissue. It may take longer for a PPI to ease your symptoms than an H2 receptor blocker, which usually starts reducing stomach acid within one hour.

How to stop taking PPIs?

When you stop taking PPIs, you may experience an increase in acid production. This increase can last for several months. Your doctor may gradually wean you off these drugs to help prevent this from happening. They may also recommend taking the following steps to reduce your discomfort from any GERD symptoms: 1 eating smaller portions 2 consuming less fat 3 avoiding laying down for at least two hours after eating 4 avoiding snacks before bedtime 5 wearing loose clothing 6 elevating the head of the bed about six inches 7 avoiding alcohol, tobacco, and foods that trigger symptoms

What is the best medicine for GERD?

Your doctor may prescribe one or more medicines to treat GERD. Antacids. Doctors may recommend antacids to relieve mild heartburn and other mild GER and GERD symptoms. Antacids are available over the counter. Antacids can help relieve mild symptoms.

What is the procedure to treat GERD?

Endoscopy . In a small number of cases, doctors may recommend procedures that use endoscopy to treat GERD. For endoscopy , doctors insert an endoscope—a small, flexible tube with a light and camera—through your mouth and into your esophagus.

Can you buy over the counter GERD medication?

You can buy many GERD medicines over the counter. However, if you have symptoms that will not go away with over-the-counter medicines, you should talk with your doctor. Your doctor may prescribe one or more medicines to treat GERD.

Can antacids help with GERD?

Antacids. Doctors may recommend antacids to relieve mild heartburn and other mild GER and GERD symptoms. Antacids are available over the counter. Antacids can help relieve mild symptoms. However, you shouldn’t use these medicines every day or for severe symptoms, except after discussing your antacid use with your doctor.

Can you take antacids every day?

Antacids are available over the counter. Antacids can help relieve mild symptoms. However, you shouldn’t use these medicines every day or for severe symptoms, except after discussing your antacid use with your doctor. These medicines can have side effects, such as diarrhea or constipation. H2 blockers.

Can antacids cause constipation?

Antacids can help relieve mild symptoms. However, you shouldn’t use these medicines every day or for severe symptoms, except after discussing your antacid use with your doctor. These medicines can have side effects, such as diarrhea or constipation. H2 blockers. H2 blockers lower the amount of acid your stomach makes.

Can you buy H2 blockers over the counter?

You can buy H2 blockers over the counter, or your doctor can prescribe one. Proton pump inhibitors (PPIs). PPIs lower the amount of acid your stomach makes. PPIs are better at treating GERD symptoms than H2 blockers, and they can heal the esophageal lining in most people with GERD.

What is the best medication for GERD?

Histamine blockers ( H2 blockers or H2-receptor antagonists) are another class of medications used to treat GERD. H2 blockers, similar to PPIs, block signals from certain cells in the stomach that promote the production of stomach acid. This process reduces acid overall and may help reduce the symptoms of GERD.

What is the best treatment for GERD?

Proton pump inhibitors (PPIs) are an often-used option for managing GERD. These medications work to treat the symptoms by blocking the production of stomach acid. With less stomach acid, there may be fewer symptoms of GERD. 2

What is the common cause of GERD?

1 GERD is a condition that occurs when bile or stomach acid causes irritation in the esophagus, the hollow, muscular tube leading from the throat to the stomach. People who have symptoms of acid reflux or heartburn more ...

Can antacids help with GERD?

Antacids don’t address the source of GERD, only the symptoms, so they are typically only used for short periods of time. Some of the OTC antacids available to treat GERD include: Gaviscon (aluminum hydroxide and magnesium carbonate) Mylanta (aluminum hydroxide and magnesium hydroxide)

What is a PPI for GERD?

Proton pump inhibitors (PPIs) are an often-used option for managing GERD. These medications work to treat the symptoms by blocking the production of stomach acid. With less stomach acid, there may be fewer symptoms of GERD. 2. A PPI may be prescribed by a physician, but some forms are available over the counter.

How does PPI work?

These medications work to treat the symptoms by blocking the production of stomach acid. With less stomach acid, there may be fewer symptoms of GERD. 2. A PPI may be prescribed by a physician, but some forms are available over the counter.

Can H2 blockers be used for GERD?

This process reduces acid overall and may help reduce the symptoms of GERD. H2 blockers may not be the first choice for treating GERD, but they might be used as a "step-down" therapy to treat certain aspects of GERD. 3. There are currently two H2 blockers approved for treating GERD.

What is the best medication for GERD?

If you suffer from occasional heartburn and have not been diagnosed with GERD, nonprescription antacids such as Maalox, Mylanta, Rolaids, and Tums, or acid-reducing drugs known as H2 blockers, such as cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), and ranitidine (Zantac) will very likely provide relief.

Can you have heartburn twice a week?

If, however, you experience heartburn twice a week or more for weeks or months on end, have frequent regurgitation of food into your throat or mouth (with or without heartburn), or if your heartburn is not relieved by the drugs mentioned above, you may have GERD and may need a PPI.

Treatment

Diet

Mechanism of action

Availability

Medically reviewed by
Dr. Karthikeya T M
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Generally, the treatment begins with over-the-counter medication to control the stomach acid. If the pain prolongs for a few weeks the doctor may prescribe other treatments which include medications and surgery.
Medication

Antacids: Acts by neutralizing stomach acids, thereby providing quick relief.

Omeprazole . Aluminium hydroxide/Magnesium hydroxide/Simethicone . Magnesium Hydroxide


H-2 receptor blockers: H-2-receptor blockers do not act as quickly as antacids, but they provide longer relief and may decrease acid production from the stomach for up to 12 hours.

Cimetidine . Famotidine

Procedures

Linx surgery: Surgeon wraps a ring of tiny beads around LES, strong enough to keep the opening closed to refluxing acid but food can pass through it.

Nissen fundoplication: The upper part of the stomach is wrapped around the lower esophageal sphincter. This prevents the refluxes back in the esophagus.

Nutrition

Foods to eat:

  • Vegetables
  • Ginger
  • Oatmeal
  • Noncitrus fruits
  • Lean meats and egg whites.

Foods to avoid:

  • High fat foods
  • Tomatoes and citrus fruits
  • Chocolates
  • Garlic, onion and spicy foods
  • Caffeine and mint

Specialist to consult

Gastroenterologist
Specializes in the digestive system and its disorders.

Symptoms

  • Treatment for gastroesophageal reflux disease (GERD) usually consists of three stages. The first two stages include taking medications and making diet and lifestyle changes. The third stage is surgery. Surgery is generally used only as a last resort in very severe cases of GERD that involve complications. Proton pump inhibitors (PPIs) are one type of medication that can be used to red…
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Diagnosis

  • Most people will benefit from first-stage treatments by adjusting how, when, and what they eat. However, diet and lifestyle adjustments alone may not be effective for some. In theses cases, doctors may recommend using medications that slow or stop acid production in the stomach.
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Risks

  • PPIs work by blocking and reducing the production of stomach acid. This gives any damaged esophageal tissue time to heal. PPIs also help prevent heartburn, the burning sensation that often accompanies GERD. PPIs are one of the most powerful medications for relieving GERD symptoms because even a small amount of acid can cause significant symptoms.
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Side effects

  • PPIs are available both over-the-counter and by prescription. Over-the-counter PPIs include: Lansoprazole and omeprazole are also available by prescription, as are the following PPIs:
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