Treatment FAQ

which of the following drugs is most commonly used in the treatment of bleeding esophageal varices?

by Jarred Satterfield Published 2 years ago Updated 2 years ago

These medications include propranolol (Inderal, Innopran XL) and nadolol (Corgard). Using elastic bands to tie off bleeding veins. If your esophageal varices appear to have a high risk of bleeding, or if you've had bleeding from varices before, your doctor might recommend a procedure called endoscopic band ligation.

Beta blockers — Beta blockers, which are traditionally used to treat high blood pressure, are the most commonly recommended medication to prevent bleeding from varices.May 9, 2022

Full Answer

What medications are used to treat esophageal varices?

These medications include propranolol (Inderal, Innopran XL) and nadolol (Corgard). Using elastic bands to tie off bleeding veins. If your esophageal varices appear to have a high risk of bleeding, or if you've had bleeding from varices before, your doctor might recommend a procedure called endoscopic band ligation.

What is esophageal varices Quizlet?

Esophageal varices Flashcards - Questions and Answers | Quizlet Liver cirrhosis. Esophageal varices 1. A health care provider who has not been immunized for hepatitis B is exposed to the hepatitis B virus (HBV) through a needle stick from an infected patient.

Which medications are used in the treatment of variceal bleeding?

As many as two-thirds of patients with variceal bleeding develop an infection, most commonly spontaneous bacterial peritonitis, UTI, or pneumonia. Antibiotic prophylaxis with oral norfloxacin 400 mg or IV ceftriaxone, 1 g q24h for up to a week, is indicated.

What is the first choice of endoscopic treatment for esophageal bleeding?

The first choice of endoscopic treatment for esophageal bleeding is endoscopic variceal ligation (EVL), or endoscopic injection sclerotherapy (EIS) if EVL cannot be performed.

Which of the following is a treatment for bleeding esophageal varices?

There is a high risk that bleeding will recur in people who've had bleeding from esophageal varices. Beta blockers and endoscopic band ligation are the recommended treatments to help prevent re-bleeding.

How beta-blockers treat esophageal varices?

By slowing the heart rate and widening the blood vessels, beta-blocker medicines such as propranolol and nadolol appear to lower the blood pressure in varices that bypass the liver. In people who have esophageal varices, beta-blockers have been shown to reduce the risk of having a first episode of bleeding.

What is a long term treatment for esophageal varices?

Injection sclerotherapy remains the most widely used long-term management for patients after an esophageal variceal bleed. Sclerotherapy treatments should be repeated weekly until the varices are eradicated. Follow-up endoscopy every 6 to 12 months is required for life.

What is the recommended treatment for active variceal hemorrhage?

The current treatment options for acute variceal hemorrhage include medications (vasopressin, somatostatin, and their analogs), endoscopy, transjugular intrahepatic portosystemic shunt placement, and surgery.

Why use octreotide esophageal varices?

Octreotide reduces portal and variceal pressures as well as splanchnic and portal-systemic collateral blood flows [2]. It also prevents postprandial splanchnic hyperemia in patients with portal hypertension [3] and lowers gastric mucosal blood flow in normal and portal hypertensive stomachs [4].

How does octreotide stop variceal bleeding?

Variceal bleeding: Octreotide decreases the inflow of blood to portal system by constricting the splanchnic arterioles and significantly reduces intravariceal pressure.

Which medication is used to decrease portal pressure halting bleeding esophageal varices?

Beta blockers decrease pressure inside of the varices, which can reduce the risk of bleeding by 45 to 50 percent [1]. There are several forms of beta blockers. The two most commonly used beta blockers for prevention of bleeding are propranolol (sample brand name: Inderal) and nadolol (brand name: Corgard).

Why is Terlipressin used in variceal bleeding?

In patients with cirrhosis and variceal bleeding, the use of terlipressin reduces the portal vein pressure and decreases the pressure in esophageal varices.

What is Terlipressin used for?

Terlipressin is an analog of the vasoconstrictor vasopressin, which is used to treat bleeding esophageal varices, another sequelae of portal hypertension.

Why is nitroglycerin used for esophageal varices?

Abstract. Background: Continuous infusion of IV vasopressin have been widely used to lower portal pressure and reduce bleeding from esophageal varices. Recently, the combination of vasopressin and nitroglycerin has been noted to be superior to vasopressin alone.

Why do we give vasopressin for esophageal varices?

Vasopressin has been used for 25 years to control bleeding from esophageal varices. Its efficacy is believed to be due to a direct vasoconstrictor activity on splanchnic arterioles and precapillary sphincters, with secondary reduction in portal venous blood flow and pressure.

Why is vasopressin given to patients with bleeding from esophageal varices?

Vasopressin is commonly used in the treatment of bleeding esophageal varices. Its mechanism of action is thought to be splanchnic arteriolar vasoconstric- tion, resulting in a decrease in portal inflow and therefore pressure (1,2).

How to stop bleeding from esophageal varices?

Doctors are exploring an experimental emergency therapy to stop bleeding from esophageal varices that involves spraying an adhesive powder. The hemostatic powder is administered through a catheter during an endoscopy. When sprayed on the esophagus, hemostatic powder sticks to the varices and may stop bleeding.

What is the procedure called to check for varices in the esophagus?

A procedure called upper gastrointestinal endoscopy is the preferred method of screening for esophageal varices. Your doctor inserts a thin, flexible, lighted tube (endoscope) through your mouth and into your esophagus, stomach and the beginning of your small intestine (duodenum).

How to stop bleeding after endoscopy?

If medication and endoscopy treatments don't work, doctors may try to stop bleeding by applying pressure to the esophageal varices. One way to temporarily stop bleeding is by inflating a balloon to put pressure on the varices for up to 24 hours, a procedure called balloon tamponade.

What is the procedure to insert a tube into the esophagus?

Endoscopy. An endoscopy procedure involves inserting a long, flexible tube (endoscope) down your throat and into your esophagus. A tiny camera on the end of the endoscope lets your doctor examine your esophagus, stomach and the beginning of your small intestine (duodenum). If you have cirrhosis, your doctor should screen you for esophageal varices ...

What test is used to diagnose cirrhosis?

How often you'll undergo screening tests depends on your condition. Main tests used to diagnose esophageal varices are: Endoscopic exam. A procedure called upper gastrointestinal endoscopy is the preferred method of screening for esophageal varices.

How long does it take for octreotide to stop bleeding?

Drugs such as octreotide (Sandostatin) and vasopressin (Vasostrict) slow the flow of blood to the portal vein. The drug is usually continued for up to five days after a bleeding episode. Diverting blood flow away from the portal vein.

What to do if you have internal bleeding?

If you're having signs and symptoms of internal bleeding, call 911 or your local emergency number to be taken to the hospital for urgent care.

Why is the esophageal balloon deflated?

The health care provider inserts the tube and verifies the position. The esophageal balloon is deflated every 8 to 12 hours to avoid necrosis, but if the gastric balloon is deflated, the esophageal balloon may occlude the airway. 19.

What is a portocaval shunt?

A portocaval shunt is considered for a patient with cirrhosis following an episode of bleeding esophageal varices. The nurse plans to teach the patient that this procedure. a. is likely to improve the patient's life expectancy. b. will increase the risk of hepatic encephalopathy.

What is the definition of HBV?

1. A health care provider who has not been immunized for hepatitis B is exposed to the hepatitis B virus (HBV) through a needle stick from an infected patient. The infection control nurse informs the individual that treatment for the exposure should include

Does a nurse need to talk to a doctor before giving spironolactone?

The nurse does not need to talk with the doctor before giving the spironolactone, although the health care provider should be notified about the low potassium value. The furosemide will further decrease the patient's potassium level and should be held until the nurse talks with the health care provider. 14.

Does propranolol decrease BP?

Rationale: -blockers have been shown to decrease the risk for bleeding in esophageal varices. Although propranolol will decrease BP and prevent cardiac ischemia, these are not the purposes for this patient. Propranolol will not decrease fluid retention or edema. Cognitive Level: Application Text Reference: p. 1107.

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