Therefore, according to its mechanism of action, the targets of antibacterial drugs include cell membrane, cell wall, protein synthesis, nucleic acid synthesis, and biological metabolic compound synthesis.
What are the five major targets of antimicrobial agents?
List the five major targets of antimicrobial agents. 1) inhibition of cell wall synthesis 2) inhibition of nucleic acid structure and function 3) inhibition of protein synthesis 4) interference with cell membrane structure and function. 5) inhibition of folic acid synthesis.
What is the main goal of antimicrobial treatment?
Main goal of antimicrobial treatment. To administer a drug to an infected person that destroys the infective agent without harming the host's cells. Identify the sources for most commonly used antimicrobials.
Are antimicrobial drugs safe for people with food allergies?
Safe and effective, useful in the management of food allergies 5% of all persons taking an antimicrobial drug will experience an adverse side effect. Side effects of drugs: direct damage to tissues, allergic reactions, disruption of normal biota.
What is a superinfection Quizlet?
True or false: A superinfection is an infection occurring during antimicrobial therapy that is caused by an overgrowth of drug-resistant microorganisms. True _______ is an all-inclusive term for any drug used to fight an infection, regardless of its origin or type.
What are the major targets of antimicrobial therapy?
Five bacterial targets have been exploited in the development of antimicrobial drugs: cell wall synthesis, protein synthesis, ribonucleic acid synthesis, deoxyribonucleic acid (DNA) synthesis, and intermediary metabolism.
What are the 5 modes of antimicrobial action?
Basis of Antimicrobial Action Various antimicrobial agents act by interfering with (1) cell wall synthesis, (2) plasma membrane integrity, (3) nucleic acid synthesis, (4) ribosomal function, and (5) folate synthesis.
What are the 3 types of antimicrobial?
There are three types of public health antimicrobials: sterilizers, disinfectants, and sanitizers. See Table 2. Sanitizers are the weakest public-health antimicrobials. They reduce bacteria on surfaces.
What are the main cellular targets of antimicrobial control agents?
Two main cellular components, DNA and plasma membrane, are regarded as the most important PDI targets. Using Zn porphyrin-based PSs and Escherichia coli as a model Gram-negative microorganism, we demonstrate that efficient photoinactivation of bacteria can be achieved without detectable DNA modification.
What are the 4 targets of antimicrobial agents?
1). Therefore, according to its mechanism of action, the targets of antibacterial drugs include cell membrane, cell wall, protein synthesis, nucleic acid synthesis, and biological metabolic compound synthesis.
What are the 5 characteristics of an ideal antimicrobial agents?
An ideal antimicrobic: - soluble in body fluids, - selectively toxic, - nonallergenic, - reasonable half life (maintained at a constant therapeutic concentration) - unlikely to elicit resistance, - has a long shelf life, - reasonably priced.
What is antimicrobial treatment?
An antimicrobial therapy kills or inhibits the growth of microorganisms such as bacteria, fungi, or protozoans. Therapies that kill microorganisms are called microbiocidal therapies and therapies that only inhibit the growth of microorganisms are called microbiostatic therapies.
What are examples of antimicrobials?
What are examples of antimicrobials?Penicillin (an antibiotic).Valacyclovir (an antiviral agent).Fluconazole (an antifungal medication).Praziquantel (an antiparasite medication).
What are the five main classes of antimicrobial drugs?
Antibacterials are used to treat bacterial infections. Antibiotics are classified generally as beta-lactams, macrolides, quinolones, tetracyclines or aminoglycosides. Their classification within these categories depends on their antimicrobial spectra, pharmacodynamics, and chemical composition.
Which two of the following are targets of antibacterial drugs that inhibit nucleic acid synthesis?
The nucleic acid synthesis inhibitors rifamycins and fluoroquinolones target bacterial RNA transcription and DNA replication, respectively.
Which of the following need to be considered when selecting an antimicrobial?
The use of antibiotics requires a consideration of three elements: the antibiotic, the organism, and the patient. The antimicrobial susceptibility of a micro- organism can be determined easily.
What are the 6 mechanisms of antimicrobial action?
Antimicrobial agents can be divided into groups based on the mechanism of antimicrobial activity. The main groups are: agents that inhibit cell wall synthesis, depolarize the cell membrane, inhibit protein synthesis, inhibit nuclei acid synthesis, and inhibit metabolic pathways in bacteria.
What is a prebiotic?
prebiotic. Used to replace microbiota lost during antimicrobial chemotherapy. probiotic. True or false: A superinfection is an infection occurring during antimicrobial therapy that is caused by an overgrowth of drug-resistant microorganisms.
Can bacteriophage infect bacteria?
c. bacteriophage cannot infect antibiotic resistant microbes. d. bacteriophage are effective against bacteria and fungi. a. bacteriophage are specific to a single species of microbe. b. bacteriophage have been shown to be active against microbes in biofilms.