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Asystole is treated by cardiopulmonary resuscitation (CPR) combined with an intravenous vasopressor such as epinephrine (a.k.a. adrenaline). Sometimes an underlying reversible cause can be detected and treated (the so-called "Hs and Ts", an example of which is hypokalaemia).
What is the treatment for asystole?
When treating asystole, epinephrine can be given as soon as possible but its administration should not delay initiation or continuation of CPR. After the initial dose, epinephrine is given every 3-5 minutes. Rhythm checks should be performed after 2 minutes (5 cycles) of CPR.
When should epinephrine be given to a patient with asystole?
For most patients, true asystole is the result of a prolonged illness or cardiac arrest, and prognosis is very poor. The few patients that have a positive outcome following a diagnosis of cardiac arrest with asystole will usually result from the identification and correction of an underlying cause of the asystole.
What is the prognosis of asystole?
ACLS Asystole Treatment Algorithm Conduct an initial patient assessment, checking for respirations and pulse If the patient is not breathing and has no pulse, start CPR Establish an airway and administer oxygen to keep oxygen saturation above 94%
What is the ACLS asystole treatment algorithm?

What is the most appropriate treatment for a patient in asystole?
The only two drugs recommended or acceptable by the American Heart Association (AHA) for adults in asystole are epinephrine and vasopressin. Atropine is no longer recommended for young children and infants since 2005, and for adults since 2010 for pulseless electrical activity (PEA) and asystole.
Which intervention is most appropriate for the treatment of a patient in asystole ACLS?
When treating asystole, epinephrine can be given as soon as possible but its administration should not delay initiation or continuation of CPR. After the initial dose, epinephrine is given every 3-5 minutes. Rhythm checks should be performed after 2 minutes (5 cycles) of CPR.
What is treatment during asystole?
Standard drug therapy for asystole during cardiac arrest includes epinephrine, atropine, and calcium chloride (CaCl). Recent studies have shown that ventricular fibrillation (VF) can appear to be asystole when recorded from the chest surface.
When the patient is in asystole the preferred initial treatment is?
If the initial rhythm is pulseless electrical activity or asystole, an initial dose of epinephrine 1 mg IV/IO (intravenous/intraosseous) should be administered as soon as possible after recognition of cardiac arrest.
Will AED shock asystole?
Children or adults who develop cardiac arrest caused by a slowing of the heart rate (bradycardia) or cardiac standstill (asystole) cannot be treated with an AED. These rhythms do not respond to electric shocks, so the AED will not allow a shock to be activated and standard CPR measures should be performed.
When do you give adrenaline in asystole?
When adrenaline is used, it should be used as soon as possible when the cardiac arrest rhythm is non-shockable, and after 3 defibrillation attempts for a shockable cardiac arrest rhythm.
Is vasopressin given for asystole?
In addition, both vasopressin and epinephrine were included among prompt resuscitative measures recommended for the treatment of ventricular asystole.
What happens when a patient is in asystole?
Asystole is a type of cardiac arrest, which is when your heart stops beating entirely. This usually makes you pass out. It's also likely that you'll stop breathing or that you'll only have gasping breaths. Without immediate CPR or medical care, this condition is deadly within minutes.
Do you give amiodarone for asystole?
Amiodarone serum level was within therapeutic range. The possible electrophysiologic mechanisms by which amiodarone might suppress both normal and abnormal pacemakers are discussed. The occurrence of asystole at therapeutic serum concentration of amiodarone suggests that this drug should be used with caution.
What is asystole?
Asystole, colloquially referred to as flatline, represents the cessation of electrical and mechanical activity of the heart. Asystole typically occurs as a deterioration of the initial non-perfusing ventricular rhythms: ventricular fibrillation (V-fib) or pulseless ventricular tachycardia (V-tach).
Which of the following treatment options are administered during cardiopulmonary resuscitation?
Overview. In its full, standard form, cardiopulmonary resuscitation (CPR) comprises 3 steps: chest compressions, airway, and breathing (CAB), to be performed in that order in accordance with American Heart Association (AHA) guidelines.
How do you confirm asystole?
Answer: The standard practice for an ACP to confirm asystole is to use multiple leads to check for lack of electrical activity. According to the Medical Cardiac Arrest Medical Directive the patient must meet the conditions (arrest not witnessed by EMS AND no ROSC AND no shocks delivered).
What is the best medicine for asystole?
For asystole, the standard medication to use is epinephrine.
What is an asystole?
Asystole, otherwise known as a flatline, is a state of cardiac standstill in which all electrical activity has ceased.
How often should you do a rhythm check for CPR?
Following the initial dose, epinephrine is given every 3-5 minutes as needed. During CPR, a rhythm check should be done every 2 minutes (5 cycles). These rhythm checks should be kept to less than 10 seconds, in order to prevent meaningful interruptions in CPR.
What to do if your rhythm is incorrect?
If you believe the rhythm may be incorrect, ensure patches have good contact with the individual, leads are connected, the gain is set appropriately, and the power is on. If all equipment appears to be functioning normally, and you still see a rhythm that appears to be asystole, quick action is imperative.
Is defibrillation effective for asystole?
Because asystole is not a shockable rhythm, defibrillation is not an effective asystole treatment. Researchers estimate that less than two percent of people who suffer asystole outside of the hospital will survive - even with trained emergency intervention.
Is asystole a flatline?
Identifying Asystole. Confirmation that the rhythm is indeed a flatline, and not a false positive, is an important part of the asystole treatment algorithm. For most patients, true asystole is the result of a prolonged illness or cardiac arrest, and prognosis is very poor.
