Treatment FAQ

which injectable to use in the treatment of intrinsic sphincter deficiency?

by Joe Lesch Published 3 years ago Updated 2 years ago
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The injection of glutaraldehyde cross-linked collagen (Contigen) is a recently approved method for treating patients with urinary incontinence secondary to intrinsic sphincter deficiency (ISD).

GAX collagen is an effective treatment modality for stress urinary incontinence caused by intrinsic sphincter deficiency in the neuropathic urethra.

Full Answer

What is a bulking agent used for?

A bulking agent is a material injected into the wall of the urethra to improve urethral coaptation in women suffering from stress incontinence. The concept was initially described in the 1930s when sodium morrhuate and paraffin were used to augment urethral resistance.

How is intrinsic sphincter deficiency diagnosed?

Intrinsic sphincter deficiency (ISD) is a pathologic condition that is diagnosed by using urodynamics to measure Valsalva leak point pressure and maximal urethral closure pressure.

What is intrinsic sphincter deficiency?

Intrinsic Sphincter Deficiency (ISD) occurs when there is weakness of the urethral sphincter. ISD may be caused by genetics, nerve damage from prior surgery, or neurological disorders.

What is bulking agent made of?

Urethral bulking agents reported in the literature include autologous fat, glutaraldehyde cross-linked bovine collagen, calcium hydroxylapatite, pyrolytic carbon-coated beads, polydimethylsiloxane, ethylene vinyl alcohol copolymer, dextranomer hyaluronic acid, and polytetrafluoroethylene.

What is Macroplastique injection?

Macroplastique is an injectable soft-tissue urethral bulking agent for treating stress urinary incontinence primarily due to Intrinsic Sphincter Deficiency.

How can I stop SUI?

What Lifestyle changes can treat SUI?Absorbent Pads. You may need to rely on absorbent pads daily or from time to time. ... Pelvic Floor Muscle Exercises (also called Kegel exercises) ... Maintain Good Bowel Function. ... Maintaining a Healthy Weight. ... Bladder Training. ... Quit Smoking.

What is a Coaptite injection?

What is Coaptite? Coaptite is used to help control urine (pee) leakage caused by a weak urinary sphincter. This is a permanent urethral implant. This is a procedure that is done in our office with local anesthesia.

How do you strengthen your urethral sphincter?

How to perform kegel exercisesSit on the toilet and start to urinate.Try to stop the flow of urine midstream by contracting your pelvic floor muscles.Repeat this action several times until you become familiar with the feel of contracting the correct group of muscles. ... This method of contraction is a kegel exercise.

What is a urethral bulking agent?

Urethral bulking agent injections are used to treat urinary incontinence, the accidental leakage of urine. During this procedure, a bulking agent such as silicon is injected into the wall of the urethra, the tube that carries urine from your bladder to outside your body.

What is a Bulkamid injection?

Bulkamid is a thick, permanent gel used to treat women who have stress urinary incontinence due to weak pelvic floor (urethral sphincter) muscles. The Bulkamid Urethral Bulking System is a single-use kit that consists of sterile syringes filled with the Bulkamid gel, a rotatable sheath, and injection needles.

How long does Bulkamid injection last?

Bulkamid injections are an effective and safe first-line treatment option for women with SUI or stress-predominant MUI providing durable outcomes at 7 years.

Is Bulkamid injection painful?

A number of small injections - typically three to four – are needed to administer the treatment. If it's done under local anaesthetic, you may feel a sting, however, the procedure can be performed under general anaesthetic if you would like it to be.

Why do women have weak sphincters?

For women in particular, having weak sphincters could lead to a form of incontinence. Sphincters are the muscles within the urinary system that allow the body to hold in urine. If the sphincter muscles stop working, urine leakage will ...

What causes incontinence in women?

The inability to control urine, known as incontinence, can affect any individual for a host of different reasons. For women in particular, having weak sphincters could lead to a form of incontinence. Sphincters are the muscles within the urinary system that allow the body to hold in urine. If the sphincter muscles stop working, urine leakage will result. This condition is known as intrinsic sphincter deficiency. There are treatment options available for this disorder. One of the most common remedies is known as intrinsic sphincter deficiency repair—a procedure in which collagen implant injections are inserted through a needle into the wall of the urethra creating a blockage of urine flow from the bladder. This procedure might not be suited for everyone, so it is best for patients to consult with their physician for the best course of treatment.

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