Metronidazole is highly effective in the treatment of many anaerobic bacterial and protozoal infections. Oral metronidazole is the drug of choice for trichomoniasis.
What are the most common treatments for trichomoniasis?
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Is there any over the counter medication for trichomoniasis?
The nitroimidazoles are the only class of antimicrobials known to be effective against trichomonas infection. Metronidazole resistance occurs in 4%–10% of cases of vaginal trichomoniasis ( 1116, 1118 ). Tinidazole resistance is less well studied but was present in 1% of infections in one study ( 1116 ).
Can trichomoniasis go away on its own?
Oct 01, 2001 · Nitroimidazoles (such as metronidazole [Flagyl]) are the most effective treatment for parasitological cure of trichomoniasis.
How do you cure trichomoniasis?
Apr 22, 2003 · Nitroimidazole drugs are effective in the treatment of trichomoniasis in women. Trichomoniasis is a sexually transmitted infection that affects about 120 million women worldwide every year. This review examines the effectiveness of various treatments and found that oral nitroimidazole drugs are effective in treating trichomoniasis in women.
What is the treatment for trichomoniasis?
Trichomoniasis can be cured with medication prescribed by a doctor. These pills can be taken by mouth. It is safe for pregnant women to take this medication.
Resources for clinicians
Vaginitis Self-Study Module#N#external icon#N#– An online learning experience that helps users learn how to manage vaginitis. Free CME/CNE available. (November 1, 2017)
Other Management Considerations
Providers should advise persons with T. vaginalis infections to abstain from sex until they and their sex partners are treated (i.e., when therapy has been completed and any symptoms have resolved). Testing for other STIs, including HIV, syphilis, gonorrhea, and chlamydia, should be performed for persons with T. vaginalis.
Follow-Up
Because of the high rate of reinfection among women treated for trichomoniasis, retesting for T. vaginalis is recommended for all sexually active women approximately 3 months after initial treatment regardless of whether they believe their sex partners were treated ( 137, 1115 ).
Management of Sex Partners
Concurrent treatment of all sex partners is vital for preventing reinfections. Current partners should be referred for presumptive therapy. Partners also should be advised to abstain from intercourse until they and their sex partners have been treated and any symptoms have resolved.
Recurrent Trichomoniasis
A recurrent infection can result from treatment failure (antimicrobial-resistant T. vaginalis or host-related problems), lack of adherence, or reinfection from an untreated sex partner. In the case of a recurrent infection, the origin of the repeat infection should be assessed because most recurrent infections likely result from reinfection.
Special Considerations
Metronidazole and tinidazole are both nitroimidazoles. Patients with an IgE-mediated-type hypersensitivity reaction to 5-nitroimidazole antimicrobials should be managed by metronidazole desensitization according to published regimens ( 1127, 1128) and in consultation with an allergy specialist. The optimal treatment for patients with T.
Treatment
Treatment reduces symptoms and signs of T. vaginalis infection, cures infection, and might reduce transmission. Likelihood of adverse outcomes among women with HIV infection is also reduced with T. vaginalis therapy.
Clinical Scenario
A 26-year-old woman presents with a yellow vaginal discharge, vaginal itching and soreness, and mild dyspareunia. No cervicitis is found but, on wet mount, numerous motile protozoa consistent with Trichomonas vaginalis are seen.
Clinical Question
What is the most effective treatment strategy for women diagnosed with vaginal trichomoniasis?
Evidence-Based Answer
Nitroimidazoles (such as metronidazole [Flagyl]) are the most effective treatment for parasitological cure of trichomoniasis. Single-dose treatment is as effective as longer term treatment but increases side effects.
Practice Pointers
In women with trichomoniasis, physicians can treat both the patient and her partner with a single dose of metronidazole (e.g., one 2-g oral dose) in return for a 90 percent chance of parasitological cure in one month.
How long does it take to cure trichomoniasis?
Typically, you take one dose consisting of several tablets, or a weeklong course of an antibiotic tablet twice a day. If you’re like most people, you’re cured in about a week.
How long after taking a syringe can you take it?
Some doctors suggest you don’t take it at all if you’re breastfeeding. The CDC suggests that you stop breastfeeding and don’t start again until 3 days after you’ve taken your last dose. If you’re unsure what to do, you can talk it through with your doctor to see what’s best for you and your baby.
Can you drink alcohol while taking metronidazole?
With either drug, you’ll need to avoid drinking alcohol for a short period. You’ll need to avoid drinking while you are taking the drug and for at least 3 days after taking the last dose.
