A. The client must have functioning pancreatic beta cells. Rationale: Because glyburide stimulates pancreatic beta cells to produce more insulin, it is effective only when functioning pancreatic beta cells are present. A client's current condition requires rapid reduction of blood sugar levels.
Full Answer
Which is a priority action of the nurse when administering glyburide?
Conditions that glyburide oral Treats What Conditions does GLYBURIDE Treat? type 2 diabetes mellitus diabetes during pregnancy Full Drug Information Available coupons Save up to …
What is the mechanism of action of glyburide?
May 27, 2020 · Glyburide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Glyburide is not for treating type 1 diabetes. Warnings You should not use glyburide if you are being treated with bosentan ( Tracleer ), or if you have diabetic ketoacidosis (call your doctor for treatment).
When should I take glyburide for type 2 diabetes?
Oct 11, 2016 · The nurse knows teaching has been effective when the patient states, "I need to monitor for dizziness, lightheadedness, and sweating if I take: The physician prescribes glyburide (Micronase, DiaBeta, Glynase) for a patient, age 57, when diet and exercise have not been able to control type 2 diabetes.
What lab tests should I do to check my response to glyburide?
Which condition must be met in order for glyburide treatment to be effective? The client must have functioning pancreatic beta cells. A client’s current condition requires rapid reduction of blood sugar levels.
When should a patient take glyburide?
It is usually taken once a day with breakfast or the first main meal of the day. However, in some cases your doctor may tell you to take glyburide twice a day. To help you remember to take glyburide, take it at around the same time(s) every day.
What is the purpose for taking glyburide?
Glyburide is used to treat high blood sugar levels caused by a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream.
What do you monitor for glyburide?
Consistent monitoring of blood glucose and HbA1C is vital in determining treatment success with glyburide.Jul 19, 2021
What adverse reaction related to glyburide needs to be considered before beginning a dental procedure on this client?
Your dosage may need to be increased. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
What should you assess before starting glyburide?
AssessmentObserve for signs and symptoms of hypoglycemic reactions (sweating, hunger, weakness, dizziness, tremor, tachycardia, anxiety). Patients on concurrent beta-blocker therapy may have very subtle signs and symptoms of hypoglycemia.Assess patient for allergy to sulfonamides.
What is the basic pharmacologic mechanism of action for glyburide?
Glyburide appears to lower blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets. The mechanism by which glyburide lowers blood glucose during long-term administration has not been clearly established.
When should I take glyburide for gestational diabetes?
Per protocol, hypoglycemic medications are initiated when ≥ 50% of finger stick blood sugars are elevated from target values of <95 mg/dL fasting and <120 mg/dL at two hours postprandial. If started on glyburide, patients are instructed to take their medication thirty minutes prior to expected mealtime.Sep 14, 2015
How quickly does glyburide work?
Depending on whether you are taking the non-micronized (Diabeta) or the micronized (Glynase) formulation of the medication will determine how long it takes for the medication to work. Generally, Diabeta (glyburide) lowers your blood sugar anywhere from 15 to 60 minutes after taking the dose.
Which is the best indicator of overall diabetic control?
Glycated hemoglobin (A1C, hemoglobin A1C, HbA1c), which reflects average levels of blood glucose over the previous two to three months, is the most widely used test to monitor chronic glycemic control. It is used to diagnose diabetes and to monitor the efficacy of treatment.Feb 15, 2022
What are the most common adverse effects of glyburide?
The more common side effects that can occur with glyburide include:diarrhea.dizziness.headache.heartburn.nausea.gas.weight gain.
What are the most common adverse effects of glyburide micronase )?
Common side effects may include:low blood sugar;nausea, heartburn, feeling full;muscle or joint pain;blurred vision; or.mild rash or skin redness.
What's the side effects of glyburide?
Common side effects of glyburide (Mifeprex) include:Skin swelling.Hives.Rash.Drug rash.Itching.Photosensitivity reaction.Heartburn.Vasculitis.More items...
Before Taking This Medicine
You should not use glyburide if you are allergic to it, or if: 1. you are being treated with bosentan (Tracleer); 2. you have type 1 diabetes; or 3...
How Should I Take Glyburide?
Glyburide is usually taken with breakfast or the first main meal of the day.Follow all directions on your prescription label and read all medicatio...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A glyburide overdose can cause life-threatening hypoglycemia.Sympt...
What Should I Avoid While Taking Glyburide?
If you also take colesevelam, avoid taking it within 4 hours after you take glyburide.Avoid drinking alcohol. It lowers blood sugar and may interfe...
Glyburide Dosing Information
Usual Adult Dose for Diabetes Type 2:Standard glyburide:-Initial dose: 2.5 mg to 5 mg orally once a day-Dose titration: Increase in increments of n...
What Other Drugs Will Affect Glyburide?
Glyburide may not work as well when you use other medicines at the same time. Many other drugs can also affect blood sugar control. This includes p...
When should metformin be discontinued?
Metformin should be discontinued at least 48 hours before and after diagnostic tests that use contrast medias.
What are the symptoms of hypoglycemia?
The nurse realizes the client is experiencing symptoms of hypoglycemia when the client displays: decreased respiratory rate and hot, dry skin. increased pulse rate and fruity smelling breath. weakness, sweating, and decreased mentation. increased thirst and increased urine output.
What are the signs of diabetes?
When talking to a class of adolescent diabetics, the educator tells the students that the most recognized signs of diabetes are: hyperglycemia and glycosuria. carbohydrate use and insulin levels. protein intake and hyperglycemia. hypoglycemia and glucagon levels.
How to take glyburide?
Glyburide is usually taken with breakfast or the first main meal of the day. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
What is glyburide used for?
Glyburide is an oral diabetes medicine that helps control blood sugar levels. Glyburide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Glyburide is not for treating type 1 diabetes.
What are the symptoms of a syringe?
Call your doctor at once if you have: 1 dark urine, jaundice (yellowing of the skin or eyes); 2 severe skin rash, redness, or itching; 3 pale skin, easy bruising or bleeding; 4 fever, chills, sore throat, mouth sores; or 5 low levels of sodium in the body headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.
What are the side effects of glyburide?
low blood sugar; nausea, heartburn, feeling full; muscle or joint pain; blurred vision; or. mild rash or skin redness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Glyburide side effects (more detail)
What are the symptoms of low blood sugar?
Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency.
Does glyburide affect blood sugar?
Glyburide may not work as well when you use other medicines at the same time. Many other drugs can also affect blood sugar control. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.
What is the name of the disease that causes a lack of red blood cells?
you have diabetic ketoacidosis (call your doctor for treatment). Tell your doctor if you have ever had: hemolytic anemia (a lack of red blood cells); an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD); a nerve disorder affecting bodily functions;
How often should I take glyburide?
It is usually taken once a day with breakfast or the first main meal of the day. However, in some cases your doctor may tell you to take glyburide twice a day. To help you remember to take glyburide, take it at around the same time (s) every day.
What is glyburide used for?
Glyburide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Glyburide is in a class of medications called sulfonylureas. Glyburide lowers blood sugar by causing ...
What are the side effects of glyburide?
Glyburide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: 1 nausea 2 upper abdominal fullness 3 heartburn 4 rash
What to do if you are allergic to glyburide?
tell your doctor and pharmacist if you are allergic to glyburide, any other medications, or any of the ingredients in glyburide. Ask your pharmacist for a list of the ingredients.
Does glyburide help with diabetes?
Glyburide helps control blood sugar but does not cure diabetes. Continue to take glyburide even if you feel well.
What is the phone number to call for poison control?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Can you drink alcohol while taking glyburide?
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking glyburide. ask your doctor about the safe use of alcoholic beverages while you are taking glyburide. Alcohol can make the side effects from glyburide worse.
Usual Adult Dose for Diabetes Type 2
Standard glyburide:#N#-Initial dose: 2.5 mg to 5 mg orally once a day#N#-Dose titration: Increase in increments of no more than 2.5 mg at weekly intervals based upon blood glucose response#N#-Maintenance dose: 1.25 to 20 mg orally as a single dose or in divided doses#N#-Maximum dose: 20 mg/day#N#Micronized glyburide:#N#-Initial dose: 1.5 mg to 3 mg orally once a day#N#-Dose titration: Increase in increments of no more than 1.5 mg at weekly intervals based upon blood glucose response#N#-Maintenance dose: 0.75 to 12 mg orally as a single dose or in divided doses#N#-Maximum dose: 12 mg/day#N#Comments:#N#-Administer with breakfast or the first main meal of the day#N#-Lower initial doses may be used in patients who are sensitive to hypoglycemic drugs#N#-Once a day therapy is generally satisfactory, however, some patients may have a more satisfactory response with twice-a-day dosing, especially those receiving higher doses.#N#TRANSFER FROM OTHER HYPOGLYCEMIC THERAPY:#N#-Oral Antidiabetic Therapy: No exact dosage relationships exists between standard glyburide, micronized glyburide, or other oral hypoglycemic agents; when transferring patients from other oral hypoglycemic therapy, the maximum starting doses should be observed.#N#-Insulin:#N#--If the insulin dose is less than 20 units per day substitute 2.5 to 5 mg (standard) OR 1.5 to 3 mg (micronized) orally once a day.#N#--If the insulin dose is between 20 and 40 units per day, substitute 5 mg (standard) OR 3 mg (micronized) orally once a day.#N#--If the insulin dose is more than 40 units per day; transition the patient by concomitantly decreasing insulin by 50% and starting glyburide at 5 mg (standard) OR 3 mg (micronized) orally once a day; as insulin is progressively withdrawn, titrate glyburide in increments of 1.25 to 2.5 mg (standard) OR 0.75 to 1.5 mg (micronized) orally once a day every 2 to 10 days.#N#Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus..
Usual Geriatric Dose for Diabetes Type 2
Initial dose:#N#Standard: 1.25 to 2.5 mg orally once a day#N#Micronized: 0.75 to 1.5 mg orally once a day#N#Titration: See Adult Dosing
Renal Dose Adjustments
Use with caution; initial and maintenance doses should be conservative to avoid hypoglycemic reactions#N#-Initial dose: 1.25 mg (standard) or 0.75 mg (micronized) orally once a day
Liver Dose Adjustments
Use with caution; initial and maintenance doses should be conservative to avoid hypoglycemic reactions#N#-Initial dose: 1.25 mg (standard) or 0.75 mg (micronized) orally once a day
Dose Adjustments
Initial and maintenance doses should be conservative in patients at risk for serious hypoglycemic reactions#N#-Initial dose: 1.25 mg (standard) or 0.75 mg (micronized) orally once a day#N#Micronized glyburide tablets (Glynase Prestab) are not bioequivalent to standard glyburide formulations (DiaBeta, Micronase); patients should retitrate dose when transferring from one formulation to the other#N#No exact dosage relationship exists between glyburide and other oral hypoglycemic agents; however, a maintenance dose of glyburide 5 mg/day provides approximately the same degree of blood glucose control as chlorpropamide 250 to 375 mg/day, tolazamide 250 to 375 mg/day, acetohexamide 500 to 750 mg/day, or tolbutamide 1000 to 1500 mg/day.#N#-Patients should not exceed maximum starting doses when switching agents.
Precautions
CONTRAINDICATIONS:#N#-Hypersensitivity to the active substance or any product excipients#N#-Type 1 diabetes mellitus#N#-Diabetic ketoacidosis, with or without coma#N#-Concomitant administration of bosentan#N#Safety and efficacy have not been established in patients younger than 18 years.#N#Consult WARNINGS section for additional precautions.
Other Comments
Administration advice:#N#-Take orally once a day with first main meal of the day#N#-When coadministered with colesevelam, this drug should be taken at least 4 hours prior#N#-Missed doses should not be corrected by doubling the next dose.
How Effective is Glyburide?
Glyburide is a diabetes medicine that is administered orally and assists in regulating blood sugar levels. Glyburide is utilized effectively in treatment of type 2 diabetes and is not used in treating type one diabetes.
What is the Recommended Dosage of Glyburide?
First dose: Administer glyburide orally 1.5 milligrams (micronized) or 2.5 milligrams (standard) once daily with morning meal.
What are the Side Effects of Glyburide?
Seek emergency medical assistance if you experience symptoms of allergic reactions to glyburide such as breathing problems, hives or swelling of your throat, tongue, face and lips.
Medical uses
- Glyburide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Glyburide is in a class of medications called sulfonylureas. Glyburide lowers blood sugar by causing the pancreas ...
Usage
- Glyburide comes as a tablet to take by mouth. It is usually taken once a day with breakfast or the first main meal of the day. However, in some cases your doctor may tell you to take glyburide twice a day. To help you remember to take glyburide, take it at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to e…
Treatment
- Your doctor will probably start you on a low dose of glyburide and gradually increase your dose if needed. After you have taken glyburide for some time, glyburide may not control your blood sugar as well as it did at the beginning of your treatment. Your doctor may adjust the dose of your medication as needed so that the medication will work best for you. Be sure to tell your doctor h…
Diet
- Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. It is important to eat a healthy diet, exercise regularly, and lose weight if necessary.
Preparation
- Before you start to take glyburide, ask you doctor what you should do if you forget to take a dose. Write these directions down so that you can refer to them later.
Prevention
- As a general rule, take the missed dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moist…
Risks
- Glyburide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). In one study, peopl…
Results
- Keep all appointments with your doctor and the laboratory. Your fasting blood sugar levels and glycosylated hemoglobin (HbA1c) should be checked regularly to determine your response to glyburide. Your doctor may order other lab tests to check your response to glyburide. Your doctor will also tell you how to check your response to this medication by measuring your blood sugar l…