| Drug Class | Generic Name (Other names and acronyms) | Brand Name |
|---|---|---|
| Nucleoside Reverse Transcriptase Inhibitors (NRTIs) | ||
| Fusion Inhibitors | ||
| Fusion inhibitors block HIV from entering the CD4 T lymphocyte (CD4 cells) of the immune system. | enfuvirtide (T-20) | Fuzeon |
| CCR5 Antagonists | ||
What stops HIV from entering cells?
To infect a cell, HIV has to bind to two types of molecules on the cell's surface. Blocking either of these molecules prevents HIV from entering the cells. Attachment inhibitors bind to a specific protein on the outer surface of HIV. This prevents HIV from entering the cell.
Which of the following drugs acts by preventing the HIV virus from attaching to immune cells?
CCR5 blockers, such as maraviroc, as well as CXCR4 blockers, are examples of these ARV drugs. They work by blocking cell receptors, called CCR5 and CXCR4, respectively, and prevent HIV from attaching to the host cell, interrupting the HIV life cycle in its earliest stages.
What is the current treatment for HIV?
The treatment for HIV is called antiretroviral therapy (ART). ART involves taking a combination of HIV medicines (called an HIV treatment regimen) every day. ART is recommended for everyone who has HIV. ART cannot cure HIV, but HIV medicines help people with HIV live longer, healthier lives.
What are the three medications for HIV?
The following combination drugs are made up of either two or three NRTIs: abacavir, lamivudine, and zidovudine (Trizivir) abacavir and lamivudine (Epzicom) emtricitabine and tenofovir alafenamide fumarate (Descovy)
What is Ziagen used for?
ZIAGEN tablets and oral solution, in combination with other antiretroviral agents, are indicated for the treatment of human immunodeficiency virus (HIV-1) infection.
How do NRTIs and NNRTIs work?
The reverse transcriptase inhibitors (NRTIs, NNRTIs) suppress HIV replication by competitive inhibition of viral reverse transcriptase. PIs prevent the late stages of viral replication by interfering with the formation of structural proteins of the virion core.
What is the AZT?
AZT, in full azidothymidine, also called zidovudine, drug used to delay development of AIDS (acquired immunodeficiency syndrome) in patients infected with HIV (human immunodeficiency virus). AZT belongs to a group of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).