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Dec 30, 2017 · Phototherapy is one of the topical treatment methods that is best medically demonstrated in terms of treating morphea. The functional principle of this therapy is based on exposing skin lesions to ultraviolet radiation, which according to its wavelength can be divided into three basic subtypes, such as UVA (UVA1 and UVA2 are distinct), UVB (broadband UVB …
What is the best treatment for morphea?
Conclusion: Phototherapy, methotrexate/systemic corticosteroids, calcipotriene, and topical tacrolimus have the most evidence for efficacy in morphea. Treatment works best in inflammatory disease. Disease activity, severity, progression, and depth should play a role in therapeutic decision making. Copyright © 2010 American Academy of Dermatology, Inc. …
Does morphea go away on its own?
Jul 17, 2021 · 20 participants at any age with plaque, linear, or atrophic morphea. Fractional carbon dioxide laser 10,600 nm, 1×/month for 3 months versus. UVA1 (340–400 nm) 3×/week for 8 weeks. Unknown status; Primary outcome measures. Efficacy of fractional carbon dioxide laser (over 12 weeks) Secondary outcome measures.
Which phototherapy modalities are used in the treatment of morphea?
Nov 01, 2011 · A. Morphea (pronounced more-FEE-ah) is a fairly unusual skin condition. I see perhaps one or two cases a year. The plaque type — which is the most common and probably what your wife has — affects women more often than it does men and typically is seen on the trunk. It's caused by an overproduction of collagen by cells in the skin called ...
Which medications are used in the treatment of juvenile morphea?
Oct 04, 2018 · Current first-line treatments with the most evidence for efficacy in morphea include phototherapy, methotrexate, systemic corticosteroids, calcipotriene, and topical tacrolimus. 7 However, there is no consensus on the treatment of morphea, and most of the studies are case series, with very few comparative or placebo-controlled clinical trials. 8 Management of …
What kind of doctor treats morphea?
You may start by seeing your primary care doctor. He or she may refer you to a doctor who specializes in skin disorders (dermatologist) or a specialist in diseases of the joints, bones and muscles (rheumatologist).Oct 9, 2020
How do you get rid of morphea naturally?
5 Ways to Relieve Morphea ItchMoisturize your skin. The main morphea symptoms are tight, hard, and dry discolored patches on the skin. ... Get out in the sun. Another inexpensive morphea treatment includes getting more sunlight. ... Try phototherapy. ... Use a medicated cream. ... Avoid itchy situations.
How do you get rid of morphea?
There is no cure for morphea. Type of treatment depends on the type of morphea and how severe it is. Current treatment is aimed at controlling symptoms until the morphea goes away on its own, typically within five years.
Is sunlight good for morphea?
Sun exposure may be helpful for morphea lesions, but do not over do it. Ten to 15 minutes of exposure to midday sunlight two to three times per week may improve the morphea lesions.
Does morphea ever go away?
Morphea usually has a benign, self-limited course and life expectancy is typically normal. When lesions are superficial and circumscribed, the skin condition tends to slowly go away with time, with each individual lesion lasting an average of 3-5 years. However, some patients develop new lesions over their lifetimes.
Is morphea serious?
Morphea can cause a number of complications, including: Self-esteem issues. Morphea can have a negative effect on your self-esteem and body image, particularly if discolored patches of skin appear on your arms, legs or face. Movement problems.Oct 9, 2020
What foods should be avoided with scleroderma?
REFLUX/HEARTBURN: eat small frequent meals to avoid overfilling your stomach; avoid eating within 2-3 hours of bedtime; avoid foods that may aggravate symptoms such as citrus fruits, tomato products, greasy fried foods, coffee, garlic, onions, peppermint, gas-producing foods (such as raw peppers, beans, broccoli, raw ...
Can morphea be misdiagnosed?
Its clinical findings are diverse, ranging from erythematous to hypopigmented or hyperpigmented patches or plaques1. Due to this variability, morphea may be misdiagnosed especially by non-dermatologists as pigmentary disorders such as vitiligo2.
Is morphea an autoimmune disorder?
Morphea is an autoimmune disease that causes sclerosis, or scarlike, changes to the skin. Autoimmune diseases occur when the immune system, which normally protects us from bacteria, viruses, and fungi, mistakenly attacks a person's own body.
What autoimmune disease causes morphea?
It is thought to be isolated to the skin without internal organ involvement as seen in systemic sclerosis (commonly known as scleroderma). Morphea is an autoimmune disorder (such as type I diabetes, lupus, vitiligo, or multiple sclerosis, among others).
Does morphea make you tired?
Most patients with generalized morphea and eosinophilic fasciitis reported fatigue, and a substantial proportion of patients noted severe fatigue. Patients with eosinophilic fasciitis particularly reported pain and itch.Oct 20, 2008
What is Generalised morphea?
Generalized morphea is defined as more than 4 indurated plaques larger than 3 cm each and/or involving 2 of more of 7 anatomic sites (head-neck, each extremity, anterior trunk, and posterior trunk) but sparing the face and hands.
What is the best homeopathic remedy for rash?
Analysis of the rubrics scored Rhus toxicodendron, also known as the Atlantic poison oak ( Toxicodendron pubescens ), as the top remedy. A review of homeopathic materia medica and provings indicated clinical use of both Rhus tox and Rhus radicans in dermatological conditions characterized by rash, stiffness, induration, yellow or white discoloration, and anxiety with restlessness. 10 Rhus radicans, also known as the Eastern poison ivy ( Toxicodendron radicans ), is symptomatically a close relative of the well-known homeopathic remedy Rhus toxicodendron. Rhus radicans is a poisonous Asian and North American flowering plant that causes intense pruritus, erythema, and dermatitis on contact.
What is homeopathy medicine?
As a complementary and alternative medicine, homeopathy is a whole-systems approach to healthcare that is prescribed based on the patient’s entire pattern of symptoms, including the physical, emotional, mental, and spiritual factors of disease, to treat root causes and provide highly individualized treatment.
Does methotrexate cause nausea?
Chronic use of methotrexate can result in liver damage and side effects including nausea and vomiting, mouth ulcers, and anemia. Treating scleroderma in earlier stages is generally more successful at reducing inflammatory activity compared to treating sclerosis featuring chronic, well-established lesions. 9.
Does Rhus Radicans help with morphea?
The homeopathic medicine Rhus radicans was clinically shown to improve morphea, a rare skin condition that is historically difficult to treat.
How long does it take for morphea to respond to hydroxychloroquine?
However, in 2019, a retrospective study of 84 adults with morphea treated with at least 6 months of hydroxychloroquine showed 43% of patients had a complete response, with only 7.1% having no response. [ 78]
How long does MTX last?
[ 66, 67, 68, 69, 70] To minimize the risk of relapse, the recommended treatment duration of MTX is at least 2 years. [ 71]
What is the wavelength of UVA?
There are many types of phototherapy, including narrowband UVB (310-311 nm), broadband UVB, broadband UVA (320-400 nm), long-wavelength UVA (UVA1; 340-400 nm, low- or medium-dose), and psoralen plus UVA chemotherapy (PUVA). All modalities have been reported to be beneficial, with UVA being the most studied to date.
Is reducing inflammation in early disease more successful than sclerosis?
[ 55] In general, therapy aimed at reducing inflammatory activity in early disease is more successful than attempts to decrease sclerosis in well-established lesions. [ 56]
Is UVA1 more effective than UVB?
In a randomized trial comparing the efficacy of different forms of phototherapy for morphea, medium dose UVA1 (50 J/cm 2) was found to be significantly more effective than narrowband UVB.
What Is The Best Medicine For Morphea?
There is no one best medicine for morphea and the treatment is highly individualized. The treatment should be started with topical medicines, but in rapidly progressive cases, topical medicines are not sufficient, so it mandates system therapy, such as systemic corticosteroid and methotrexate as first line therapy.
Symptoms Of Morphea
The clinical presentation of morphea or localized scleroderma is diverse depending on the subdivision of the disease, localization of the condition and the depth of involvement. Broadly it can be classified as circumscribed, linear, generalized, pansclerotic and mixed.
What is the best treatment for morphea?
Phototherapy (especially UVA1) Currently, phototherapy is one of the best treatment options in morphea when it does not involve subcutis or below. The highest level of evidence is broad-band UVA (320 to 400nm wavelength), narrow-band UVB (wavelength centered around 311 nm), UVA1 (340 to 400nm wavelength).
What is the cause of morphea in children?
Morphea causes functional, psychologic, and neurologic complications. Morphea in children may cause growth retardation and muscular atrophy of affected limbs as well as limitation of range of motion and contracture, especially in deep lesions spanning joints or affecting the majority of the surface area of an extremity. Pain, sometimes severe, is reported in patients with deep involvement or circumferential involvement of an extremity.
Is methotrexate good for morphea?
Advise patients to avoid extensive sun exposure and tanning beds and to be screened for cancerous lesions annually. Methotrexate (MTX) is one of the best systemic treatment options for morphea. Oral or intravenous (IV) glucocorticoids may be used along with methotrexate in rapidly progressive or inflammatory disease.
Is morphea present in children?
Morphea may present at any age. In children, the linear subtype predominates while in adults’ plaque and generalized subtypes are most common. Morphea occurs more frequently in women, especially in adults where female predominance is marked (5:1).