Treatment FAQ

when patients are in the manic phase are often resistive to treatment because of?

by Pablo Feil Published 3 years ago Updated 2 years ago

What is therapy resistant mania in the elderly?

A group of elderly bipolar patients develops therapy resistant mania with persistent psychotic symptoms. These patients may require institutional care until they "burn-through" their disease; a process that may require years to stabilize. Mania is a complex disorder in the elderly.

How long does it take to recover from a manic episode?

Because the median duration of a manic episode is approximately 13 weeks, it is crucial for patients and their immediate family to recognize that recovery might be gradual, and that it will likely take time before she (he) can resume full-time responsibilities at work or school or in the home.23

Which medications are approved for the treatment of manic episodes?

Olanzapine, risperidone, quetiapine, aripiprazole and asenapine were approved by the FDA for the treatment of acute manic episodes. Olanzapine, aripiprazole, quetiapine and ziprasidone were approved as monotherapy for maintenance treatment as well.

Should manic elderly patients with psychosis stop all medications?

Manic elderly patients who are stressed by psychotic agitation may stop all medications including cardiac medicines, antihypertensives, etc. The clinicians must carefully weigh the medical risk of sustained anti-manic therapy verses the medical risk of acute psychosis.

How is bipolar resistant treatment?

Treatment-resistant bipolar depression Only 2 have been FDA-approved: quetiapine and a combination of olanzapine and fluoxetine. Other treatments that have been recommended include lithium and lamotrigine. If any of these standard treatments is partially effective, an increase in dose may be considered.

What happens to patients in a manic state?

Symptoms of a manic episode Feeling extremely happy or excited — even euphoric. Not sleeping or only getting a few hours of sleep but still feeling rested. Having an inflated self-esteem, thinking you're invincible. Being more talkative than usual.

What happens during a manic phase?

In the manic phase of bipolar disorder, it's common to experience feelings of heightened energy, creativity, and euphoria. If you're experiencing a manic episode, you may talk a mile a minute, sleep very little, and be hyperactive. You may also feel like you're all-powerful, invincible, or destined for greatness.

What are the factors affecting mania?

The 4 classic defining features of mania appeared as 3 factors in this analysis: factors 2 (psychomotor pressure), 4 (increased hedonic function comprising euphoric mood and grandiosity), and 5 (irritable aggression).

How is manic behavior treated?

You'll typically need mood-stabilizing medication to control manic or hypomanic episodes. Examples of mood stabilizers include lithium (Lithobid), valproic acid (Depakene), divalproex sodium (Depakote), carbamazepine (Tegretol, Equetro, others) and lamotrigine (Lamictal).

What is manic behavior?

The terms "mania" and "manic episode" describe a state of mind characterized by high energy, excitement, and euphoria over a sustained period of time. It's an extreme change in mood and cognition that can interfere with school, work, or home life. Mania is also the main feature of bipolar disorder.

What causes mania in bipolar?

Possible causes of hypomania or mania include: high levels of stress. changes in sleep patterns or lack of sleep. using recreational drugs or alcohol.

What is the manic phase of bipolar disorder?

Both a manic and a hypomanic episode include three or more of these symptoms: Abnormally upbeat, jumpy or wired. Increased activity, energy or agitation. Exaggerated sense of well-being and self-confidence (euphoria)

What happens after a manic episode?

After a manic or hypomanic episode you might: Feel very unhappy or ashamed about how you behaved. Have made commitments or taken on responsibilities that now feel unmanageable. Have only a few clear memories of what happened during your episode, or none at all.

What happens in the brain during mania?

We found significantly decreased frontal cortical volume (dorsolateral prefrontal and inferior frontal cortex) in the Mania group, but no volume changes in the No-Mania group. Our results indicate that volume decrease in frontal brain regions can be attributed to the incidence of manic episodes.

What is mania a symptom of?

Mania is a psychological condition that causes a person to experience unreasonable euphoria, very intense moods, hyperactivity, and delusions. Mania (or manic episodes) is a common symptom of bipolar disorder.

What is the pathophysiology of mania?

PATHOPHYSIOLOGY. Organic lesions associated with manic syndromes involve the areas of the brain that modulate neurovegetative functions (such as sleep, appetite, libido, and energy) and emotion. Organic psychoses: delusional disorders and secondary mania.

What is a bipolar phase?

Bipolar Phases. Highs and lows associated with emotion are usually temporary for most people . People with bipolar disorder, however, experience more dramatic changes in mood. These shifts are often referred to as bipolar phases or bipolar episodes.

What can a therapist do to help with bipolar disorder?

Therapists can help educate clients and their family members/significant others about bipolar disorder and teach ways to be supportive during episodes. Psychotherapy also focuses on recognizing potential triggers for changes in episodes and ways to avoid triggers, such as avoiding stressful situations and behaviors.

Why do people have bipolar disorder?

The exact cause of bipolar disorder remains unknown among mental health professionals. Scientists believe that there is a genetic component that may cause the disorder to run in some families. However, while people are genetically predisposed to be at risk of developing bipolar disorder, not everyone who has a family member with the disorder will experience it. Environmental factors such as gender, stress, and alcohol or substance abuse are also thought to be contributing factors to the development of bipolar disorder.

What are the factors that increase the risk of bipolar disorder?

Other factors, such as physical or sexual abuse (especially in the early developmental stages of life), or the death of a parent or other traumatic events are also believed to increase the risk of bipolar disorder later in life.

What percentage of the population is affected by bipolar disorder?

The National Institute of Mental Health reports that approximately 2.6 percent of the adult population in the United States is affected by bipolar disorder.

Can bipolar disorder cause manic episodes?

The manic symptoms of bipolar disorder may be especially difficult for some people to understand as people may react differently during these episodes. For example, when manic episodes occur, one person may experience mania or hypomania episodes with feelings of frustration or irritability while another may exhibit a decreased need for sleep, accelerated thinking, or hyperactivity.

Is hypomania a form of bipolar disorder?

Hypomania is a less severe form of mania. During episodes of hypomania, mood and energy levels are heightened, but they are not “out of control.”. The depressive symptoms associated with bipolar disorder are very similar to those of other major depressive episodes.

What are the three forms of mania?

Mania in the elderly occurs in three forms: (1) Bipolar patients who get older (2) elderly patients with pre-existing depression who develop manic symptoms and (3) elderly patients who first present with mania.

Who cares for elderly bipolar patients?

Families care for most elderly bipolar patients and most caregivers are spouses. The stress of bereavement over caregiver illness or death will often trigger affective symptoms in otherwise stable patients. The absence of caregiver support will complicate management of the patient.

What causes bipolar disorder?

Well-controlled bipolar patients become unstable for many reasons. Patients have worsening of symptoms as a result of: 1 medication non-compliance 2 medical problem 3 natural history, i.e., changes in the symptoms over time 4 caregiver death 5 delirium 6 substance abuse 7 inter-current dementia

What is an atypical antipsychotic?

Atypical anti-psychotic can be used to manage patients unable to take mood stabilizers or who fail to respond to single agent therapy. Each of the atypical anti-psychotics is compatible with major mood stabilizers such as lithium, tegretol, and valproic acid.

Is mania a complex disorder?

Mania is a complex disorder in the elderly. Management of the elderly manic requires a sophisticated management strategy that accounts for biomedical psychosocial aspects of the disease. next: Personal Stories on Living with Bipolar Disorder Table of Contents. ~ bipolar disorder library. ~ all bipolar disorder articles.

Can elderly people have mania?

A group of elderly bipolar patients develops therapy resistant mania with persistent psychotic symptoms. These patients may require institutional care until they "burn-through" their disease; a process that may require years to stabilize. Mania is a complex disorder in the elderly.

Can ACE inhibitors cause mania?

Many medications can destabilize mood. Antidepressants and steroids commonly provoke manic symptoms but ACE inhibitors (angiotensin converting enzyme); thyroid supplementation and AZT will also cause mania in the elderly.

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