Promethazine has mutliple uses. It is most often used to prevent or treat nausea and vomiting related to certain conditions (motion sickness, pregnancy, chemotherapy). It is also used to treat allergic reactions (hives, swelling, closing of the throat) or allergy symptoms (rash, itching, and runny nose).
What is promethazine used to treat after surgery?
Promethazine (Phenergan) is used to treat allergy symptoms, nausea and vomiting after surgery and to prevent motion sickness. Includes promethazine side effects, interactions and indications. Promethazine (Phenergan) is used to treat allergy symptoms, nausea and vomiting after surgery and to prevent motion sickness.
When was promethazine first used to treat cancer?
A safe and humane treatment for cancer based on Dr Mahmud’s observations and effective in the early stages of disease became available at the end of 1994. Promethazine, the active principle of the therapy, was introduced into clinical practice in 1947 and is long out of patent.
What is the best time of day to take promethazine?
Promethazine is often taken at bedtime or before meals. For motion sickness, promethazine is usually started within 1 hour before traveling. When used for surgery, promethazine is usually taken the night before the surgery.
What are the side effects of chemotherapy with promethazine?
ChemoExperts Tips. Notify your doctor or nurse immediately if you feel discomfort during the infusion. If you have a central line (port), the risk of this adverse reaction is much lower Drowsiness is a very common side effect of promethazine (Phenergan ®) and may increase your risk of falling down and getting injured.
Should I take anti nausea meds before chemo?
Three studies have found that a combination of two medicines: netupitant, an experimental medicine, and Aloxi, a standard anti-nausea medicine, works better to control chemotherapy-induced nausea and vomiting better than standard anti-nausea treatments.
Why would promethazine be prescribed?
Promethazine is used to relieve or prevent the symptoms of hay fever, allergic conjunctivitis (inflammation of the eye), and other types of allergy or allergic reactions. It works by preventing the effects of a substance called histamine, which is produced by the body.
What medication do you take before chemotherapy?
Corticosteroids, such as dexamethasone and methylprednisolone. Monoamine antagonists, such as olanzapine. Serotonin antagonists, such as dolasetron, granisetron. Substance P/NK1 Antagonists, including aprepitant, fosaprepitant and others.
What is the first thing to introduce to chemotherapy?
Beginnings. The beginnings of the modern era of cancer chemotherapy can be traced directly to the German introduction of chemical warfare during World War I. Among the chemical agents used, mustard gas was particularly devastating.
What is promazine used to treat?
Promazine is a phenothiazine used to manage schizophrenia. A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Do chemo side effects get worse with each treatment?
The effects of chemo are cumulative. They get worse with each cycle. My doctors warned me: Each infusion will get harder. Each cycle, expect to feel weaker.
How long after your first chemo treatment do you get sick?
Acute nausea and vomiting usually happens within minutes to hours after treatment is given, and usually within the first 24 hours. This is more common when treatment is given by IV infusion or when taken by mouth.
What happens on the first day of chemotherapy?
Your nurse will begin with a saline solution through your IV. As soon as the medications are delivered, your nurse will hang the bags of medication on the IV stand and then start the different IVs. You'll be given pre-medications first, then the chemotherapy.
How many rounds of chemo is normal?
During a course of treatment, you usually have around 4 to 8 cycles of treatment. A cycle is the time between one round of treatment until the start of the next. After each round of treatment you have a break, to allow your body to recover.
What is the success rate of chemotherapy?
Around 13% of lung cancers are small-cell. Most people with this type receive chemotherapy. Approximately 83% of lung cancers are N-SC....Lung cancer.N-SC lung cancer stageSurgery plus chemo and/or radiotherapy16%7%Chemo alone1%18%Chemo plus radiotherapy without surgery6%35%Total24%60%1 more row
How long does chemo take to shrink a tumor?
In general, chemotherapy can take about 3 to 6 months to complete. It may take more or less time, depending on the type of chemo and the stage of your condition.
Before Taking This Medicine
Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young child...
How Should I Take Promethazine?
Take promethazine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include overactive reflexes, loss of coordina...
What Should I Avoid While Taking Promethazine?
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fas...
Promethazine Side Effects
Get emergency medical help if you have any signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throa...
Promethazine Dosing Information
Usual Adult Dose of Promethazine for Anaphylaxis:Parenteral: 25 mg IV or IM once, followed by close observation for response. This dose may be repe...
What Other Drugs Will Affect Promethazine?
Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can...
When was Promethazine first used?
Promethazine, the active principle of the therapy, was introduced into clinical practice in 1947 and is long out of patent. In marked contrast with standard cancer drugs, no fatalities appear to have been recorded despite widespread international use.
How long did Promethazine last?
Tragically the treatment was stopped prematurely after five months, far too soon. Recommencement produced no advantage, and the patient died eighteen months later.
What is the active drug in cancer treatment?
Their diverse uses include the treatment of schizo- phrenia, nausea and pain. The active drug in this form of cancer treatment is the phenotianzine Phenergan (promethazine), currently used as an anti-histamine, as a paediatric sedative, and to quell travel sickness.
How does chemotherapy prevent cancer?
Conventional chemotherapy has for the most part sought to prevent the growth of cancers by using poisons to block the division of cancer cells. Unfortunately maintenance of the mammalian body involves cellular division within all organs, especially the bone marrow and mucosal surfaces of the intestine.
What was the name of the drug that Dr. John F. Kennedy gave to his patients?
He had three patients with inoperable cancer of the pancreas, a painful form of cancer with a bad prognosis. Initially he gave promethazine, an anti-histamine and paediatric sedative, by the intravenous route. The drug was followed by calcium, and then given orally every eight hours.
When did Dr Mahmud's research become available?
a very modest scale. A safe and humane treatment for cancer based on Dr Mahmud’s observations and effective in the early stages of disease became available at the end of 1994.
When did cancer chemo start?
Cancer chemotherapy began in the wake of World War II, when American doctors obtained limited success in treating patients with derivatives of highly toxic mustard gas. Since those early days a huge variety of chemical means of inducing the death of cancers in the living body have been devised.
How long before surgery can you take promethazine?
For motion sickness, promethazine is usually started within 1 hour before traveling. When used for surgery, promethazine is usually taken the night before the surgery. How often you take this medicine and the timing of your dose will depend on the condition being treated.
How to avoid promethazine?
Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Drinking alcohol can increase certain side effects of promethazine. Avoid exposure to sunlight or tanning beds.
How does Promethazine work?
Promethazine is in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals in your brain. Promethazine also acts as an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body.
What to do if you don't have a dose measuring device?
If you do not have a dose-measuring device, ask your pharmacist for one. If a child is using this medicine, tell your doctor if the child has any changes in weight. Promethazine doses are based on weight in children, and any changes may affect your child's dose.
Is promethazine safe for a person with COPD?
To make sure promethazine is safe for you, tell your doctor if you have: asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder; a sulfite allergy; a history of seizures; a weak immune system (bone marrow depression); glaucoma; enlarged prostate or problems with urination;
Can you give a child promethazine?
These could be early signs of dangerous side effects. Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in a child in very young children. Carefully follow your doctor's instructions when giving this medicine to a child of any age.
Can a 2-year-old take Promethazine?
Before taking this medicine. Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young children. Carefully follow your doctor's instructions when giving this medicine to a child of any age.
What is Promethazine used for?
Promethazine oral tablet is used to treat several conditions, such as allergies, motion sickness, nausea and vomiting, anxiety before surgery, and pain after surgery. It’s also used as a sleep aid, including before and after surgery.
Why do older people take drugs so slowly?
This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time . This increases your risk of side effects.
How to avoid interactions with medications?
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
What to do if you have serious side effects?
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Is Promethazine a generic drug?
Promethazine oral tablet is available as a generic drug only. It doesn’t have a brand-name version. Promethazine comes in four forms: oral tablet, oral solution, injectable solution, and rectal suppository.
Can you give Promethazine to a pregnant woman?
This drug should not be given to a pregnant woman within 2 weeks of delivery because it raises the risk of bleeding in the newborn. For women who are breastfeeding: Promethazine may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child.
Does promethazine cause drowsiness?
When you take certain nausea and motion sickness drugs with promethazine, certain side effects may increase and last longer. These side effects include dry mouth, constipation, trouble emptying your bladder, blurred vision, and drowsiness. Examples of these drugs include:
How to prepare for chemotherapy?
If you are the person responsible for meals, consider making some meals before you begin chemotherapy and freeze them in containers that offer the correct portions.
How to help someone with chemotherapy?
Consider help at home . Many times, your friends and family members want to know what they can do to help you during your chemotherapy. Give them a job - it will help both of you. Some ideas include: 1 Helping with meals 2 Helping with child care 3 Helping with house cleaning 4 Helping with transportation 5 Running errands 6 Keeping you company
How long after chemo can you get a wig?
If you are female and preparing for chemotherapy, it may be wise to get your annual PAP smear before chemotherapy begins, to avoid false abnormal results. Sometimes chemotherapy can affect the cells on the cervix for 6 months to a year after chemotherapy. Get a wig if you will need one. If you are likely to lose your hair due ...
How to get chemo through vein?
If you will be receiving your chemotherapy through a vein in your arm, make sure your sleeves will allow good access past your elbow. Talk with your boss at work. Depending on your work situation, it may be wise to discuss your chemotherapy situation with your boss. Ask if there is any flexibility in scheduling.
What to wear for chemo?
Many times it's nice to have a support person with you during treatment as well. Wear comfortable clothing . If you will be getting chemotherapy, it is best to wear comfortable clothing .
Can you watch children while on chemo?
You may need to arrange for child care both during treatment and afterwards. In most cases, you will be unable to watch young children while you are receiving your chemotherapy. Once you are at home, you may or may not feel up to the challenge.
Can you get a PAP smear for chemo?
Get a PAP smear. If you are female and preparing for chemotherapy, it may be wise to get your annual PAP smear ...
When is the first round of chemo?
on September 23, 2020. If you're about to go for your first round of chemotherapy, you may have lots of questions along with some fears. Your oncologist will talk about the drugs you will receive and potential side effects, as well as how often you will need to be seen. Yet there are many tips that don't often make their way into those ...
How long before chemo do you eat?
Two to three hours before an infusion, eat light and make your choices high-fiber. Chemo drugs tend to slow peristalsis (digestion and bowel processes), so whatever you eat may be in your digestion for longer than usual and will dry out. 1
Why is drinking water important for chemo?
A benefit of drinking enough water is that it will help your body to process and flush the chemo drugs out of your system sooner, so you can start to recover sooner, too.
How to get hydrated after chemo?
Staying Hydrated by Drinking Fluids. Chemotherapy drugs are very drying to your body's tissues, and the drugs will be going to every cell you have. Right after an infusion, drink 8 ounces of water every hour until bedtime. Avoid caffeine, as it is also drying (it's a diuretic) and may cause you to feel worse.
How to recover from chemo?
Remember that chemo affects every cell in your body. Stay well-hydrated by drinking lots of water or juice . If you feel fuzzy brained from the medications, try a hot tub soak.
What are the side effects of chemotherapy?
If you have side effects from chemotherapy that are bothersome, such as nausea, vomiting, rash, swelling, or unusual pain around the injection site, write these down. Your doctor or nurse will need to know how often you're having problems, how severe they are, and how you're coping.
What blood test is done before chemo?
Before you have each round of chemo, you will have a blood test called a complete blood count (CBC). Your CBC provides a reading on all of the types of blood cells produced by the bone marrow which can be affected by chemotherapy. Your red blood cell count and hemoglobin are looked at to see if you have anemia.
Introduction
Self-Medication - The Schedule
- The treatment is in four parts: If possible patients should begin to take nutritional supplements, especially polyunsaturated fatty acids, several days before starting with Phenergan. All supplements should be continued for the entire duration of the therapy. In most countries Phenergan can be freely purchased in the form of 10mg and 25mg tablets; ...
Contra-Indications
- Cancer patients are unlikely to benefit from this treatment if: Serious pain calls for professional attention. Paracetamol in moderation is suitable; so are opiates (for example, morphine) given on prescription. Provided the pain is not too severe, electrical stimulation with a TENS device (transcutaneous electrical nerve stimulation) can provide a limited measure of relief. Polyunsatu…
Response to Therapy
- A general improvement in terms of weight gain, improved sleep, restored appetite and general well being should be perceptible at least by the end of the first week. Lessening of pain is an encouraging sign, but where there is involvement of bone several weeks may pass before relief is noticed. A record of body weight should be kept. The advice on offer is gentle and humane; for t…
Side Effects
- The commonest of these is sedation; on the whole patients do not find the experience unpleasant, but driving a car and using machinery or sharp tools are not recommended, at least for the first fortnight. Some patients are quite unaffected. Drowsiness in the first few days after commencing Phenergan normally lasts not more than a week. In a few cases sedation persists; more rarely p…
Duration of Treatment and Outcome
- Very reasonably, patients may ask whether their particular form of disease is likely to respond to the self-medication procedure described here. The therapy takes advantage of a metabolic weakness common to all malignant tissues so far examined; in theory, then, all cancers should be amenable to treatment. Forms of the disease which have displayed sensitivity include non-Hodg…
Precautions
- A leaflet is provided with the Phenergan packet; the advice given should be read and, apart from discontinuation, adhered to. Alcohol does not interfere with the anti-cancer action, but abstinence is advised. Exposure to ultraviolet light and sunlight, especially sunbathing, are to be avoided as far as possible. The group of drugs known as monoamine oxidase inhibitors must not be taken i…
Relationship of The Patient with The Doctor and Cancer Specialist
- Cancer is a serious disease and should at all times be regarded accordingly. The help and support of medial advisers is valuable and must at all costs be enlisted and retained.Being secretive is discourteous; keeping your oncologist fully informed is essential, and may stimulate genuine interest and additional sympathy. The patient who manages best is sufficiently brave to face th…
Orthodox Treatment and Self-Medication
- In England doctors make great efforts to sustain hopes of remission, and are the beneficiaries of measures of deep faith from their patients. Optimism is seen as a valuable asset. An understandable reluctance exists to tell a patient that a condition is incurable, a shattering experience for which few are prepared. Self-delusion, though, is dangerous. Patients have turne…
Alternative Approaches
- Modern medicine is often miraculous. Antibiotics, transplants, open-heart surgery, joint replacements come to mind. Unhappily the conventional treatment of cancer has not kept pace with other advances in healthcare. The failure of medicine opens the door to the glib operator anxious to line his pockets at the expense of the desperate. Critics of alternative treatments are …