What is Fosamax used for?
Lumbar spinal stenosis is found among people who take Fosamax, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years. The phase IV clinical study analyzes which people take Fosamax and have Lumbar spinal stenosis. It is created by eHealthMe based on reports of 94,665 people who have side effects when taking ...
What should I do if I have serious side effects from Fosamax?
Spinal fusion surgery is found among people who take Fosamax, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years. The phase IV clinical study analyzes which people take Fosamax and have Spinal fusion surgery.
Does Fosamax increase BMD in the spine?
Nov 02, 2020 · Fosamax is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely. Store at room temperature away from moisture and heat. Your doctor will determine how long to treat you with this medicine.
How does Fosamax treat Paget’s disease of bone?
Aug 13, 2020 · Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill; Risedronate (Actonel), a weekly or monthly pill; Ibandronate (Boniva), a monthly pill or quarterly intravenous (IV) infusion; Zoledronic acid (Reclast), an annual IV infusion
What is the best treatment for osteoporosis of the spine?
Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.
How can I strengthen my spinal osteoporosis?
The Best Exercises For OsteoporosisWalking.Jogging.Climbing stairs.Jumping rope.Hiking.Dancing.Pilates & yoga.Sep 8, 2020
Do side effects of Fosamax go away?
How long do side effects from Fosamax last? It depends. Certain side effects, such as heartburn or nausea, may go away after you've taken a few doses of Fosamax. However other side effects, such as bone pain or a low blood calcium level, may not go away after a few doses of the drug.
What happens if you take too much Fosamax?
Overdose symptoms may include muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior. Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking alendronate and cholecalciferol.
Does walking help osteoporosis of the spine?
As counterintuitive as it may seem, certain types of exercise can actually help prevent and manage osteoporosis. Low-impact weight-bearing exercises (such as walking) help build bones and keep them strong, according to the National Osteoporosis Foundation (NOF).Nov 26, 2019
How do you reverse spinal osteopenia?
There's no cure for osteopenia, but it's important to preserve bone density as much as possible. Treatment involves simple strategies to keep your bones as healthy and strong as possible and prevent progression to osteoporosis: Calcium treatment.Sep 29, 2021
How long does it take for Fosamax to strengthen bones?
Response and effectiveness. Fosamax starts to affect markers that reflect bone resorption within one month of treatment and reaches a plateau by three to six months. Effects remain stable following continued treatment for up to three years.Feb 16, 2022
Why was Fosamax taken off the market?
Researchers say that the fractures occurred because alendronate stops the body from breaking down bone. This creates thick, but brittle bones. In October 2010, the FDA ordered Merck to change its drug label to reflect the bone-fracture connection. Fosamax use may also make fractures more difficult to heal.
How long does it take for Fosamax to leave your system?
After a 2-h intravenous infusion, plasma concentrations of alendronate decline rapidly to approximately 5% of initial values within 6 h. About 50% of a systemic dose is excreted unchanged in the urine in the 72 h following administration.
What happens when you stop taking alendronate?
If you stop taking the drug suddenly or don't take it at all: If you don't take this drug, you may have a higher risk for bone breaks. If you miss doses or don't take the drug on schedule: Your medication may not work as well or may stop working completely.
Does Fosamax increase bone density?
Fosamax and other drugs such as Actonel, Boniva, and Reclast increase bone density and help prevent and treat osteoporosis and/or reduce the risk of fractures.Jul 16, 2010
What are the long term side effects of alendronate?
Serious side effects of alendronate include:Severe pain (joints, bone, muscle, jaw, back, or heartburn)Chest pain.Difficulty swallowing.Bloody stools.Eye pain.Skin blisters.Swelling of the face, tongue, or throat.
Before Taking This Medicine
You should not take Fosamax if you are allergic to alendronate, or if you have: 1. low levels of calcium in your blood (hypocalcemia); or 2. proble...
How Should I Take Fosamax?
Take Fosamax exactly as prescribed by your doctor. Fosamax is taken either once daily or once per week. Follow all directions on your prescription...
Fosamax Dosing Information
Usual Adult Dose for Osteoporosis:Treatment of Osteoporosis in Postmenopausal Women; To Increase Bone Mass in Men with Osteoporosis:-10 mg orally o...
What Happens If I Miss A Dose?
Once-daily dosing: If you forget to take Fosamax first thing in the morning, do not take it later in the day. Wait until the following morning and...
What Happens If I Overdose?
Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do n...
What Should I Avoid While Taking Fosamax?
Avoid taking any other medicines for at least 30 minutes after taking alendronate. This includes vitamins, calcium, and antacids. Some medicines ca...
What Other Drugs Will Affect Fosamax?
Tell your doctor about all your current medicines and any you start or stop using, especially: 1. aspirin; or 2. NSAIDs (nonsteroidal anti-inflamma...
Which Medications Are Commonly Used For Osteoporosis Treatment?
Bisphosphonates are the most common medications prescribed for osteoporosis treatment. These include: 1. Alendronate (Fosamax) 2. Risedronate (Acto...
How Do Most Osteoporosis Medications Work?
With the exception of teriparatide, osteoporosis medications slow bone breakdown. Healthy bones continuously break down and rebuild.As you age — es...
How Do You Know If You're Taking The Right bisphosphonate?
Drugs in the bisphosphonate class are more alike than they are different. They all help maintain bone density. And, all bisphosphonates have been s...
When Might Other Osteoporosis Medications Be used?
Drugs such as denosumab, teriparatide and abaloparatide can be used by anyone with osteoporosis, but are more likely to be recommended for people w...
What Are Common Side Effects of Bisphosphonate pills?
Bisphosphonate pills aren't absorbed well in the stomach. The main side effects of bisphosphonate pills are stomach upset and heartburn. Generic fo...
Do Intravenous Bisphosphonates Have Advantages Over The Pill form?
Infused forms of bisphosphonates don't cause stomach upset. And it may be easier for some women to schedule a quarterly or yearly infusion than to...
Can Bisphosphonates Hurt Your Bones?
Long-term bisphosphonate therapy has been linked to a rare problem in which the upper thighbone cracks and may break. This injury, known as atypica...
How Long Should You Take A Bisphosphonate For Osteoporosis Treatment?
There's some uncertainty about how long to take bisphosphonates because of a lack of long-term studies. Bisphosphonates have been shown to be safe...
What Happens If You Break A Bone While Taking An Osteoporosis medication?
Osteoporosis medications lower the chance of fracture, but they don't eliminate all risk of breaking a bone. If you have a fracture while on treatm...
Can Medication Alone Successfully Treat Osteoporosis?
Don't rely entirely on medication as the only treatment for your osteoporosis. These practices also are important: 1. Exercise. Weight-bearing phys...
What is Fosamax?
Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 93,226 Fosamax users for its effectiveness, alternative drugs and more.
What is Spinal fusion surgery?
Spinal fusion surgery is found to be associated with 544 drugs and 296 conditions by eHealthMe.
How to use the study?
You can use the report to supplement drug labels on your pill bottles or discuss it with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
How the study uses the data?
The study uses data from the FDA. It is based on alendronate sodium (the active ingredients of Fosamax) and Fosamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature.
We work with your doctor to manage your meds!
When serious adverse effects are detected in your trial, your doctor will be notified to check them out promptly. What you need to do:
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
Why is Fosamax used?
Fosamax is used in women to treat or prevent osteoporosis caused by menopause and in men and women to treat osteoporosis caused by taking steroids. Fosamax is also used to increase bone mass in men who have osteoporosis, and to treat Paget's disease of bone in men and women.
How long does Fosamax last?
Your doctor will determine how long to treat you with this medicine. Fosamax is often given for only 3 to 5 years. Detailed Fosamax dosage information.
What are the side effects of Fosamax?
trouble swallowing; problems with your stomach or digestion; low levels of calcium in your blood; a dental problem (you may need a dental exam before you begin taking Fosamax); kidney disease; or. any condition that makes it hard for your body to absorb nutrients from food (malabsorption).
What are the symptoms of low calcium levels?
signs of low calcium levels - muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes). bone pain, muscle or joint pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Can Fosamax cause jaw pain?
Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Fosamax, the more likely you are to develop this condition. Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids.
Can you take fosamax if you are allergic to alendronate?
You should not take Fosamax if you are allergic to alendronate, or if you have: problems with the muscles in your esophagus (the tube that connects your mouth and stomach). Do not take Fosamax if you cannot sit upright or stand for at least 30 minutes. Fosamax can cause serious problems in the stomach or esophagus.
How often is romosozumab given?
Romosozumab is given as a monthly injection at your doctor's office. It is a new drug and less is known about long-term side effects, but it is not given to people who have recently had a stroke or heart attack. Treatment stops after 12 monthly doses.
What is the best treatment for osteoporosis?
Bisphosphonates are usually the first choice for osteoporosis treatment. These include: 1 Alendronate (Fosamax), a weekly pill 2 Risedronate (Actonel), a weekly or monthly pill 3 Ibandronate (Boniva), a monthly pill or quarterly intravenous (IV) infusion 4 Zoledronic acid (Reclast), an annual IV infusion
How does osteoporosis medication work?
Because bone rebuilding cannot keep pace, bones deteriorate and become weaker. Most osteoporosis medications work by reducing the rate at which your bones break down. Some work by speeding up the bone-building process. Either mechanism strengthens bone and reduces your risk of fractures.
What are the side effects of bisphosphonate?
The main side effects of bisphosphonate pills are stomach upset and heartburn. Don't lie down or bend over for 30 to 60 minutes to avoid the medicine washing back up into the esophagus. Most people who follow these tips don't have these side effects. Bisphosphonate pills aren't absorbed well by the stomach.
Can you take bisphosphonate with water?
Bisphosphonate pills aren't absorbed well by the stomach. It may help to take the medication with a tall glass of water on an empty stomach. Don't put anything else into your stomach for 30 to 60 minutes, after which you can eat, drink other liquids and take other medications.
How long can you take bisphosphonate?
These bone-building drugs can be taken for only one or two years and the benefits begin disappearing quickly after you stop. To protect the bone that's been built up, you'll need to start taking a bone-stabilizing medication such as a bisphosphonate.
Can denosumab cause osteonecrosis?
Bisphosphonates and denosumab can also cause osteonecrosis of the jaw, a rare condition in which a section of jawbone is slow to heal or fails to heal, typically after a tooth is pulled or other invasive dental work.
What is Fosamax used for?
Fosamax (alendronate sodium) is a bisphosphonate that is a specific inhibitor of osteoclast -mediated bone resorption used to both treat and prevent osteoporosis, and to treat Paget's disease. Fosamax is available in generic form.
How much Fosamax is in a bottle?
Fosamax is available in a tablet or oral liquid form. Each bottle of the oral solution contains 91.35 mg of alendronate monosodium salt trihydrate, which is the molar equivalent to 70 mg of the drug. The recommended initial dosage is one 70 mg molar equivalent tablet or oral liquid bottle once weekly or one 10 mg molar equivalent tablet per day. Fosamax must be taken at least one-half hour before the first food, beverage, or medication of the day with plain water only to avoid any reduction in gastrointestinal adsorption.
What are the side effects of calcium?
Common side effects may include: heartburn, upset stomach; stomach pain, nausea; diarrhea, constipation; or.
Can adverse reaction rates be directly compared to rates in clinical trials?
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.
Does Fosamax cause back pain?
swelling in your hands or feet, dizziness, headache, eye pain, back pain, or. weakness. Serious side effects of Fosamax include. severe pain (joints, bone, muscle, jaw, back or heartburn), chest pain, difficulty swallowing,
What are the side effects of a syringe?
Side effects requiring immediate medical attention 1 Difficulty with swallowing 2 heartburn 3 irritation or pain of the esophagus 4 muscle pain
What does it mean when your face is itching?
itching. joint pain. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs. loosening of a tooth. muscle aching or cramping. muscle cramps in the hands, arms, feet, legs, or face. numbness and tingling around the mouth, fingertips, or feet. pain or burning in the throat.
What does it mean when your eye hurts?
eye pain. feeling of constant movement of self or surroundings. general feeling of discomfort or illness. hair loss or thinning of the hair. sensation of spinning. sensitivity of the eye to light. tearing. Managing side effects (general information)
What is the new drug for osteoporosis?
A number of other osteoporosis drugs are in development, including a new monoclonal antibody (romosozumab) and drugs that block sclerostin, a protein that inhibits bone formation. However, Dr. Slovik doesn't think we're going to see any of these new drugs approved within the next year.
What is raloxifene used for?
Raloxifene (Evista), a selective estrogen receptor modulator (SERM), is perhaps best known for its role in breast cancer prevention and treatment, but it serves double duty in treating osteoporosis, too. It works by binding with estrogen receptors around the body to produce estrogen-like effects, one of which is to decrease bone turnover.
What is the process of breaking down old bone?
There's no one-size-fits-all answer. Understanding your options begins with knowing what's available. Throughout our lives, our bones undergo constant renovation. In a process called bone turnover, cells called osteoclasts break down and remove old bone, and then cells called osteoblasts lay down new bone.
How to determine if you have osteoporosis?
Your doctor will determine whether you have osteoporosis by measuring your bone density —usually at the hip and spine—using dual energy x-ray absorptiometry (DEXA).
Which is better, alendronate or risedronate?
Alendronate, risedronate, and ibandronate have all been shown effective for reducing spine fractures. For women with a history of hip or nonspinal fractures, alendronate and risedronate are better options than ibandronate.
What is a T score?
The doctor will likely recommend medicine if you have. a T-score of –2.5 or lower —the definition of osteoporosis.
How long do women take bisphosphonates?
Doctors acknowledge that the risk of these side effects also increases with long-term use of bisphosphonates, so most women take these drugs for about five years. The good news is that the bone-protective benefits continue even after you stop taking bisphosphonates.
How to treat overuse syndrome?
The easiest way to treat overuse syndrome is to stop the activities or motions that trigger your symptoms. Of course, this isn’t always possible since some of these activities are required for a specific job. If you aren’t able to completely cut out these activities, you should try to limit them as much as you can.
How to relax after a marathon?
During the day, if you need to, take breaks to rest and stretch again after excessive use of your hands and arms. Gradually relaxing your muscles : When you get home from work, don't stop using your hands and arms altogether. Think about marathon runners: They always cool down following a grueling race.
What is repetitive motion disorder?
Overuse syndrome is another term for a repetitive motion disorder. It mainly affects those who repeat certain motions over and over again during their daily activities. If you’re suffering from overuse syndrome , it will most likely affect your hands and/or arms before any other parts of the body.
What are the causes of overuse syndrome?
Performing repetitive tasks that involve your hands and arms is the main cause of this disorder. There are certain jobs and activities that can cause overuse syndrome, including: Working on an assembly line. Sewing.
Is overuse syndrome a serious condition?
You might not think overuse syndrome is a serious condition, but if you let it go unnoticed and untreated for too long, it can cause lasting damage. If you notice yourself repeating certain movements too often in your everyday life, to the point that it’s putting unwanted strain on your body, take the necessary preventative measures before it becomes a bigger problem.
How do you know if you have a trauma?
Eventually, your muscles and tissues will experience more and more trauma, resulting in pain and loss of use. Other common symptoms include: Swelling. Numbness. Gradual loss of the ability to move your hands and/or arms like you once could. Cleveland Clinic is a non-profit academic medical center.
Can you get overuse syndrome from repetitive motion?
Repeating one movement or motion constantly over a long period of time can lead to overuse syndrome in your hands and arms. Though many are able to recover from this condition, it can be very inconvenient, and can prevent you from completing everyday tasks and activities.