Treatment options
- Medication. Initially, steroids will be given to minimize the swelling around the tumor. If you’re experiencing...
- Surgery. Surgery is typically used for treating oligodendrogliomas, particularly if the tumor is low grade. However,...
- Radiotherapy. Radiotherapy involves the use of high energy rays. It’s typically used after surgery to help kill any tiny...
What are the treatment options for oligodendroglioma?
In some cases, people with oligodendroglioma need to continue treatments, including chemotherapy or radiation, to keep the tumor from growing or spreading. These treatments may continue indefinitely. After oligodendroglioma treatment, you should follow up with your doctor throughout the rest of your life.
What chemotherapy is used to treat anaplastic oligodendroglioma?
Nov 09, 2017 · A NCCTG/Mayo Clinic trial treated 28 patients with low-grade Oligodendroglioma or Oligoastrocytoma who had residual disease postoperatively with an intensified regimen of PCV, to determine the response rate and toxicity of PCV administered before radiation therapy . Radiation therapy (59.4 or 54.0 Gy) began within 10 weeks of completing chemotherapy or …
What is the prognosis for oligodendroglioma?
Apr 04, 2020 · Oligodendroglioma treatment options include: Surgery to remove the tumor. Your brain surgeon (neurosurgeon) will work to remove as much of the oligodendroglioma as... Chemotherapy. Chemotherapy uses drugs to kill cancer cells. Chemotherapy drugs can be taken in pill form or through a... Radiation ...
What are the treatment options for low-grade gliomas?
Jan 06, 2022 · Chemotherapy. The role of chemotherapy for the treatment of oligodendroglioma was well established by several studies using nitrosourea-based therapy. [ 10] Most used procarbazine, lomustine...
What does low grade oligodendroglioma mean?
Oligodendrogliomas are grouped in two grades based on their characteristics. Grade II oligodendrogliomas are low grade tumors. This means the tumor cells grow slowly and invade nearby normal tissue. In many cases, they form years before being diagnosed as no symptoms appear.Jul 21, 2021
Can a low grade brain tumor be cured?
Most low-grade gliomas are both highly treatable and highly curable. The most common kind of low-grade glioma is pilocytic astrocytoma. It has a cure rate of over 90 percent.
Can grade 2 oligodendroglioma be cured?
Oligodendroglioma, a rare tumor that starts in the brain or spinal cord, has no cure.Jan 11, 2021
How are low grade gliomas treated?
Treatment Available A low-grade glioma that is slow to grow usually does not need radiation or chemotherapy immediately. We often treat them through monitoring, surgery, radiosurgery, chemotherapy, or a combination.
Can a low grade tumor be benign?
Benign or malignant Doctors might refer to some low grade tumours as benign. And high grade tumours as malignant. This grading system generally works well for most tumours.Oct 29, 2019
What does a low grade tumor mean?
A term used to describe cells and tissue that look almost normal under a microscope. Low-grade cancer cells look more like normal cells and tend to grow and spread more slowly than high-grade cancer cells. Cancer grade may be used to help plan treatment and determine prognosis.
How long can you live with an oligodendroglioma?
As a general rule, people with grade II oligodendrogliomas are likely to live for around 12 years following diagnosis. People with grade III oligodendrogliomas are expected to live an average of 3.5 years. Do talk to your doctors. They will be able to give you a more individualized prognosis for your condition.
What are the chances of an oligodendroglioma coming back?
Prognosis. Oligodendroglioma is currently an incurable disease and the chances that it will recur and eventually progress are very high. Some people have a recurrence in 2 years and some in 10.
Is oligodendroglioma benign or malignant?
Oligodendrogliomas can be malignant (cancer) or benign (not cancer). Some of these tumors grow quickly, but many are slower. They may spread to other parts of the central nervous system (brain and spinal cord). They don't usually spread outside the central nervous system.Feb 25, 2020
Can low grade glioma be removed?
Low grade gliomas are usually treated with a combination of surgery, observation, and radiation. If the tumor is located in an area where it is safe to remove, then the neurosurgeon will attempt to remove as much as possible.
What is the standard surgical of choice for low grade glioma?
Surgical Resection Surgery remains the mainstay of therapy for most low-grade gliomas. The best outcomes are associated with optimal surgical resection. One prospective study found a 5-year overall survival rate of 97% when the extent of resection exceeded 90%, vs 76% for tumors with lesser resection.Mar 10, 2017
How long can you live with a low grade glioma?
Low grade glioma is a uniformly fatal disease of young adults (mean age 41 years) with survival averaging approximately 7 years. Although low grade glioma patients have better survival than patients with high grade (WHO grade III/IV) glioma, all low grade gliomas eventually progress to high grade glioma and death.
What is the treatment for oligodendroglioma?
Radiation therapy: Cancer specialists called radiation oncologists use high doses of X-rays to destroy what remains of the tumor after surgery. People with oligodendroglioma do not usually have radiation before surgery. Chemotherapy: Anti-cancer drugs destroy cancer cells throughout the body.
What are the prognostic factors for oligodendroglioma?
The prognosis for people with oligodendroglioma varies greatly. Factors that can affect prognosis include the tumor’s location and grade, and your age and health. Doctors can successfully treat many cases of oligodendroglioma.
What is the name of the cell that surrounds nerve cells?
Oligodendrocytes are a type of cell called glial cells. Glial cells are glue-like cells that surround nerve cells and help them function. When these cells grow uncontrollably, a tumor forms. Oligodendroglioma is a type of tumor called a glioma, named for the type of cell –glial cells– from which it develops.
How do you know if you have oligodendroglioma?
Symptoms of oligodendroglioma may include: Seizures. Headaches. Weakness on one side of the body. Language difficulty. Behavior and personality changes. Balance and movement problems. Memory problems.
What are glial cells?
Glial cells are glue-like cells that surround nerve cells and help them function . Your outcome depends on the tumor’s location and grade, and your age and health. Appointments 866.588.2264. Appointments & Locations. Contact Us. Overview. Symptoms and Causes. Diagnosis and Tests.
What is the function of oligodendrocytes?
Oligodendrocytes create a substance that protects nerves in the brain and helps them function. Oligodendrogliomas can be malignant (cancer) or benign (not cancer). Some of these tumors grow quickly, but many are slower. They may spread to other parts of the central nervous system (brain and spinal cord).
Can you get chemotherapy before or after radiation?
Doctors may recommend chemotherapy before or after radiation therapy to kill cancer cells left behind after surgery or radiation. Clinical trials: If all treatments have been tried and failed, you and your healthcare provider may want to look into clinical trials. You may meet entry criteria to join a clinical trial.
How is oligodendroglioma treated?
Oligodendroglioma treatment usually involves surgery to remove the tumor. Additional treatments may be necessary if the tumor is aggressive or is more likely to recur.
How to diagnose oligodendroglioma?
Tests and procedures used to diagnose oligodendroglioma include: 1 Neurological exam. During a neurological exam, your doctor will ask you about your signs and symptoms. He or she may check your vision, hearing, balance, coordination, strength and reflexes. Problems in one or more of these areas may provide clues about the part of your brain that could be affected by a brain tumor. 2 Imaging tests. Imaging tests can help your doctor determine the location and size of your brain tumor. MRI is often used to diagnose brain tumors, and it may be used along with specialized MRI imaging, such as functional MRI and magnetic resonance spectroscopy.#N#Other imaging tests may include CT and positron emission tomography (PET). 3 Removing a sample of tissue for testing (biopsy). A biopsy can be done with a needle before surgery or during surgery to remove your oligodendroglioma, depending on your particular situation and the location of your tumor. The sample of suspicious tissue is analyzed in a laboratory to determine the types of cells and their level of aggressiveness.#N#Specialized tests of the tumor cells can tell your doctor the types of mutations the cells have acquired. This gives your doctor clues about your prognosis and may guide your treatment options.
Where does oligodendroglioma occur?
Oligodendroglioma is a tumor that can occur in the brain or spinal cord. Oligodendroglioma forms from oligodendrocytes — cells in the brain and spinal cord that produce a substance that protects nerve cells. Oligodendroglioma can occur at any age, but most often affects adults. Signs and symptoms can include seizures and headaches.
What is the purpose of a neurologic exam?
Neurological exam. During a neurological exam, your doctor will ask you about your signs and symptoms. He or she may check your vision, hearing, balance, coordination, strength and reflexes. Problems in one or more of these areas may provide clues about the part of your brain that could be affected by a brain tumor.
How does chemotherapy kill cancer cells?
Chemotherapy. Chemotherapy uses drugs to kill cancer cells. Chemotherapy drugs can be taken in pill form or through a vein in your arm. Chemotherapy is often used after surgery to kill any cancer cells that might remain. It can be combined with radiation therapy for aggressive cancers.
Can radiation therapy be combined with chemotherapy?
Radiation therapy is sometimes recommended after surgery and may be combined with chemotherapy. Clinical trials. Clinical trials are studies of new treatments. These studies give you a chance to try the latest treatment options, but the risk of side effects may not be known.
What is the treatment for cancer?
Radiation therapy . Radiation therapy uses high-energy beams, such as X-rays or protons, to kill cancer cells. During radiation therapy , you lie on a table while a machine moves around you, directing beams to precise points in your brain.
How to treat oligodendroglioma?
Treatment options vary from conservative treatment of some patients with serial imaging studies and no intervention to aggressive multimodal treatment including surgical resection, radiotherapy, and chemotherapy in others. Because most patients either develop or present with seizures, anticonvulsive therapy is recommended once the patient is diagnosed with oligodendroglioma. See Brain Cancer Treatment Protocols for summarized information.
What is anaplastic oligodendroglioma?
Oligodendrogliomas with vascular proliferation and significant mitotic activity are best considered to be anaplastic oligodendrogliomas (World Health Organization [WHO] grade III). Oligodendrogliomas. Anaplastic oligodendrogliomas frequently take on eosinophilic cytoplasm and hyperchromasia of the nuclei.
How long does it take for a patient to die from a progressive disease?
The median time for recurrence was at least 16 months in partial responders and at least 25 months in complete responders.
Oligodendroglioma Grades and Treatment for Brain Cancer
Learn all about oligodendroglioma grades and treatment for brain cancer. Glioma is a general term for a group of tumors that start in the supportive tissues (glial cells) of the brain or spinal cord.
Oligodendroglioma (Brain Cancer)
Oligodendrogliomas are a rare type of tumour that usually starts in the brain or sometimes the spinal cord. Oligodendrogliomas most resemble oligodendrocytes, the cells that encircle and insulate the nerve cells of the brain.
Oligodendroglioma Symptoms
A person with an oligodendroglioma may display one or more of these symptoms:
What is the best treatment for oligodendrogliomas?
Surgery. Surgery is typically used for treating oligodendrogliomas, particularly if the tumor is low grade. However, surgery often doesn’t completely remove the tumor effectively, so there is a need to use other therapies following the surgery to avoid reoccurrence.
What is oligodendroglioma?
Overview. Oligodendroglioma is a rare tumor that occurs in the brain. It belongs to a group of brain tumors called gliomas. Gliomas are primary tumors. This means they have originated in the brain rather than spreading from elsewhere in the body. Around 3% of all brain tumors are oligodendrogliomas.
What are the symptoms of a tumor in the temporal lobe?
When the tumor is located in the temporal lobe, symptoms often include: loss of hearing. inability to understand language and music. memory loss. hallucinations.
Can cytotoxic drugs be used before radiotherapy?
This treatment uses cytotoxic drugs to help kill cancer cells and can be used before and after radiotherapy. It’s also useful for shrinking brain tumors, particularly those that cannot be surgically removed. It’s recommended for malignant tumors and reoccurring cases.
What is radiotherapy used for?
Radiotherapy involves the use of high energy rays. It’s typically used after surgery to help kill any tiny fragments of the tumor that may remain . It’s also used to treat malignant tumors.
Can oligodendrogliomas be removed?
There are many treatment options available and oligodendrogliomas appear to respond well to treatment. It’s unusual to be able to completely remove the disease, but it’s entirely possible to prolong the life of someone with an oligodendroglioma.