Treatment FAQ

what treatment is aggrenox

by Ismael Lockman Published 2 years ago Updated 2 years ago
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Aggrenox (aspirin / dipyridamole) contains two medications, aspirin and dipyridamole. They prevent your platelets from clumping together into blood clots. This lowers the risk of stroke, since most strokes are caused by blood clots in the vessels supplying your brain.

Precautions

  • constipation
  • diarrhea
  • dizziness
  • headache
  • nausea, vomiting
  • passing gas
  • trouble sleeping

What pain medications can you take with Aggrenox?

Works better than either aspirin or dipyridamole alone to prevent strokes. Works as well as Plavix (clopidogrel), another antiplatelet medication, to prevent stroke. Raises your risk of bleeding and bruising, which can be serious and life-threatening. May not be safe to be taken with many other medicines or supplements.

Is Aggrenox better on the stomach than aspirin?

Aggrenox (aspirin / dipyridamole) can cause liver damage or liver failure. If you have a history of liver problems, your risk of liver damage is higher. There are blood tests available to check for this problem. Tell your healthcare provider right away if you have any unusual stomach pain, nausea, or vomiting.

Are there any risks in taking Aggrenox?

Aggrenox is a prescription medicine that contains aspirin and a medicine that is slowly released in your body, called dipyridamole. Aggrenox is used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot. It is not known if Aggrenox is safe and effective in children.

What is Aggrenox prescribed for?

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What is Aggrenox used to treat?

This medication is used to reduce the risk of stroke in patients who have had "mini-strokes" (transient ischemic attacks) or a previous stroke due to a blood clot and are at high risk for another stroke.

What is the action of Aggrenox?

Aggrenox acts as an antiplatelet, preventing blood platelets from aggregating to form the dangerous clots. Platelet aggregation is actually a natural process which allows platelet cells to stick together and adhere to the blood vessel wall to prevent excessive blood loss when a blood vessel is damaged.

When should Aggrenox be used?

Aggrenox, a combination of low-dose aspirin and extended-release dipyridamole, is a new agent that is effective in the secondary prevention of stroke and transient ischemia of the brain.

Is Aggrenox an anticoagulant?

Clinical trials have demonstrated the safety and efficacy of antiplatelets for noncardioembolic stroke prevention, while anticoagulants are more often used for cardioembolic stroke prevention. Commonly used antiplatelets include aspirin, clopidogrel, and aggrenox (aspirin plus extended-release dipyridamole).

What class of drug is Aggrenox?

Aggrenox belongs to a class of drugs called Antiplatelet Agents, Hematologic.

Is Aggrenox an antiplatelet?

Aggrenox (aspirin / dipyridamole) is a combination of two antiplatelet medications that work together to prevent a stroke.

What is the difference between Plavix and Aggrenox?

Plavix (clopidogrel) is a cheap, generically available blood thinner that protects you from clots after you've had a heart attack or surgery. Prevents blood clots that can cause a stroke. Aggrenox (Aspirin / Dipyridamole) prevents blood clots and stroke, but cheaper options are available that work just as well.

What vitamins should be avoided when on blood thinners?

If you are a heart patient who is taking blood thinners, such as warfarin (Coumadin®), you need to be careful not to overdo vitamin K. Blood thinners are often prescribed for people at risk for developing harmful blood clots.

What is the difference between antithrombotic and anticoagulant?

As overview, antithrombotic therapy comprises two main classes of drugs, the anticoagulants (which inhibit various aspects of the coagulation pathways) and the antiplatelet agents (which inhibit platelet function).

Before Taking This Medicine

You should not use Aggrenox if you are allergic to aspirin or dipyridamole, or if you have: 1. asthma; 2. polyps in your nose; or 3. a history of a...

How Should I Take Aggrenox?

Take Aggrenox exactly as it was prescribed for you. Follow all directions on your prescription label. Your doctor may occasionally change your dose...

Aggrenox Dosing Information

Usual Adult Dose for Ischemic Stroke - Prophylaxis:1 tablet/capsule (25 mg aspirin/200 mg extended-release dipyridamole) orally, twice a day; 1 dos...

What Happens If I Miss A Dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...

What Happens If I Overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include warmth or tingly feeling, sweating, r...

What Should I Avoid While Taking Aggrenox?

Drinking alcohol while taking this medicine can increase your risk of bleeding.See also: Aggrenox and alcohol (in more detail)Ask a doctor or pharm...

What Other Drugs Will Affect Aggrenox?

Tell your doctor about all your current medicines and any you start or stop using, especially: 1. acetazolamide; 2. methotrexate; 3. probenecid; 4....

What are the factors that determine the labeling of Aggrenox?

Decisions to include these reactions in labeling are typically based on one or more of the following factors: (1) seriousness of the reaction, (2) frequency of reporting, or (3) strength of causal connection to Aggrenox. Body as a Whole: Hypothermia, chest pain, allergic reaction, syncope.

How long before stress test can you take Aggrenox?

Intake of Aggrenox capsules within 48 hours prior to stress testing with intravenous dipyridamole or other adenosinergic agents may increase the risk for cardiovascular side effects of these agents and may impair the sensitivity of the test.

Does Aggrenox cause birth defects?

Available data from published studies and postmarketing experience with Aggrenox use during pregnancy have not identified a clear association between Aggrenox use and major birth defects, miscarriage, or adverse maternal or fetal outcomes (see Data). Aggrenox contains low-dose aspirin which is an NSAID (see Clinical Considerations). In animal reproduction studies, there were adverse developmental effects with administration of aspirin in rats and rabbits at doses about 66 and 44 times, respectively, the human exposure at the maximum recommended daily dose of aspirin-dipyridamole. Reproduction studies with dipyridamole in mice, rabbits, and rats have revealed no evidence of harm to the fetus up to doses about 25 times the maximum recommended daily human dose of aspirin-dipyridamole. Nonclinical data are suggestive of a possible potentiation of aspirin-related fetal toxicity when combined with dipyridamole (see Data).

Can you take Aggrenox with dipyridamole?

Aggrenox is not interchangeable with the individual components of aspirin and dipyridamole tablets. The recommended dose of Aggrenox is one capsule given orally twice daily, one in the morning and one in the evening. Swallow capsules whole without chewing. Aggrenox can be administered with or without food.

Does dipyridamole increase adenosine?

Adenosinergic agents (e.g. adenosine, regadenoson) Dipyridamole has been reported to increase the plasma levels and cardiovascular effects of adenosine. Adjustment of adenosine dosage may be necessary. Dipyridamole also increases the cardiovascular effects of regadenoson, an adenosine A 2A -receptor agonist.

How to use Aggrenox

Read the Patient Information Leaflet if available from your pharmacist before you start taking this product and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Are you currently using Aggrenox?

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How does Aggrenox work?

Aggrenox (aspirin / dipyridamole) contains two medications, aspirin and dipyridamole. They prevent your platelets from clumping together into blood clots. This lowers the risk of stroke, since most strokes are caused by blood clots in the vessels supplying your brain.

How long before surgery can you stop taking Aggrenox?

For major surgeries, some people may be told to stop Aggrenox (aspirin / dipyridamole) 7 to 14 days beforehand. This may not be necessary for smaller procedures. Only stop taking Aggrenox (aspirin / dipyridamole) as your doctor or surgeon instructs.

How much aspirin is in Aggrenox?

The typical dose of Aggrenox (aspirin / dipyridamole) is 1 capsule twice a day (morning and evening). Each capsule contains 25 mg of aspirin and 200 mg of dipyridamole.

What to do if you have a rash after taking Aggrenox?

Stop taking Aggrenox (aspirin / dipyridamole) and call your healthcare provider if you notice a rash or hives after taking this medication. Get medical help immediately if you experience swelling in your face or tongue or are having trouble breathing.

Can you take Aggrenox with other blood thinners?

Tell your provider about all of your medications and medical conditions before starting Aggrenox (aspirin / dipyridamole). Don't take Aggrenox (aspirin / dipyridamole) with other blood thinning medications unless your doctor tells you it's safe.

Can Aggrenox cause bleeding?

Like all blood-thinning medications, Aggrenox (aspirin / dipyridamole) can cause unexpected bleeding or bruising. Talk to your doctor or pharmacist about how to monitor for serious bleeding problems. Avoid taking NSAID medications like ibuprofen (Advil, Motrin) or naproxen (Aleve).

Does Aggrenox contain aspirin?

Aggrenox (aspirin / dipyridamole) contains aspirin as well as a second medication called dipyridamole. People with a history of stroke or TIA (transient ischemic attack, or mini-stroke) usually have to take aspirin or Aggrenox (aspirin / dipyridamole), but not both.

How to report Aggrenox side effects?

These are not all the possible side effects of Aggrenox. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Does Aggrenox cause chest pain?

Aggrenox may cause serious side effects including: hives, difficulty breathing, swelling of your face, lips, tongue, or throat, new or worsening chest pain, lightheadedness, hearing problems, ringing in your ears, upper stomach pain,

Is Aggrenox safe for children?

Aggrenox belongs to a class of drugs called Antiplatelet Agents, Hematologic. It is not known if Aggrenox is safe and effective in children.

Does aggrenox cause birth defects?

Available data from published studies and postmarketing experience with AGGRENOX use during pregnancy have not identified a clear association between AGGRENOX use and major birth defects, miscarriage, or adverse maternal or fetal outcomes (see Data ). AGGRENOX contains low-dose aspirin which is an NSAID (see Clinical Considerations ). In animal reproduction studies, there were adverse developmental effects with administration of aspirin in rats and rabbits at doses about 66 and 44 times, respectively, the human exposure at the maximum recommended daily dose of aspirin-dipyridamole. Reproduction studies with dipyridamole in mice, rabbits, and rats have revealed no evidence of harm to the fetus up to doses about 25 times the maximum recommended daily human dose of aspirin-dipyridamole.

Does dipyridamole increase adenosine?

Dipyridamole has been reported to increase the plasma levels and cardiovascular effects of adenosine. Adjustment of adenosine dosage may be necessary. Dipyridamole also increases the cardiovascular effects of regadenoson, an adenosine A A2 -receptor agonist. The potential risk of cardiovascular side effects with intravenous adenosinergic agents may be increased during the testing period when dipyridamole is not held 48 hours prior to stress testing.

Can aspirin be taken with anagrelide?

Patients taking aspirin in combination with anagrelide are at an increased risk of bleeding. Anticonvulsants. Salicylic acid can displace protein-bound phenytoin and valproic acid, leading to a decrease in the total concentration of phenytoin and an increase in serum valproic acid levels. Beta Blockers.

Can you take aggrenox with dipyridamole?

AGGRENOX is not interchangeable with the individual components of aspirin and dipyridamole tablets. The recommended dose of AGGRENOX is one capsule given orally twice daily, one in the morning and one in the evening. Swallow capsules whole without chewing. AGGRENOX can be administered with or without food.

What is Aggrenox?

Aggrenox is a prescription medicine that contains aspirin and a medicine that is slowly released in your body, called dipyridamole. Aggrenox is used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

How should I take Aggrenox?

Take Aggrenox exactly as prescribed. Your healthcare provider will tell you how many Aggrenox to take and when to take them.

What should I avoid while taking Aggrenox?

heavy alcohol use. People who drink three or more alcoholic drinks every day have a higher risk of bleeding during treatment with Aggrenox, because it contains aspirin.

General information about the safe and effective use of Aggrenox

Medicines are sometimes prescribed for purposes other than those listed in the Patient Information. Do not use Aggrenox for a condition for which it was not prescribed. Do not give Aggrenox to other people, even if they have the same symptoms that you have. It may harm them.

What are the ingredients in Aggrenox?

Active Ingredients: dipyridamole in an extended-release form and aspirin

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Indications and Usage For Aggrenox

This medication is used to reduce the risk of stroke in patients who have had "mini-strokes" (transient ischemic attacks) or a previous stroke due to a blood clot and are at high risk for another stroke.

May Treat: Cerebral thrombosis

Drug Class: Platelet Aggregation Inhibitor Combinations

Availability: Prescription Required

Pregnancy: Consult a doctor before using

Lactation: Does not adversely affect lactation

May Treat: Cerebral thrombosis

Drug Class: Platelet Aggregation Inhibitor Combinations

Availability: Prescription Required

Pregnancy: Consult a doctor before using

Lactation: Does not adversely affect lactation

Alcohol: Limit intake while taking this medication

Driving: May cause drowsiness or dizziness. Use caution

Manufacturer: BOEHRINGER ING.

Precautions

  • If available, read the patient package insert
  • May make you dizzy. Use caution when driving.
  • Tell your pharmacist & Dr if you have allergies

  • If available, read the patient package insert
  • May make you dizzy. Use caution when driving.
  • Tell your pharmacist & Dr if you have allergies
  • Do not chew or crush
  • Swallow capsules whole.
  • Take with a full glass of water (8 ounces)
  • Call Dr if you have black stools or stomach pain
  • Limit alcohol consumption and stop using tobacco.
  • Tell Dr/dentist on drug prior to any surgery.

Aggrenox Dosage and Administration

Dosage Forms and Strengths

Contraindications

Warnings and Precautions

Adverse Reactions

Drug Interactions

Use in Specific Populations

Overdosage

Aggrenox Description

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