Treatment FAQ

what treatment groups did the pediatric ocd treatment study 1

by Stone Hayes Published 3 years ago Updated 2 years ago
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The Pediatric OCD Treatment Study is a multicenter, randomized, masked clinical trial designed to evaluate the relative benefit and durability of four treatments for children and adolescents with OCD: sertraline, CBT, combination of sertraline and CBT, and pill placebo.

Full Answer

What kind of therapy is used to treat OCD?

Types of OCD Therapy

  • Family OCD Therapy. Family therapy sessions help teach the OCD patient and family members how to function as a normal family; helps the family members focus less on the OCD ...
  • Exposure Response Prevention (ERP) Therapy. ...
  • CBT for OCD (Cognitive Behavioral Therapy) Like ERP, cognitive therapy (CT) is a type of cognitive behavioral therapy (CBT) for OCD. ...

What is an effective treatment for OCD?

Cognitive behavior therapy is an effective way to treat OCD symptoms. It can be effective with or without medication. It is a type of talk therapy that focuses on identifying and changing unhealthy thought patterns. The thought in a person with OCD comes in a familiar kind of a cycle. There is an intrusive thought that sparks anxiety.

What is the best therapy for OCD patients?

Treatments for OCD

  • Exposure Therapy. The psychotherapy of choice for the treatment of OCD is exposure and response prevention (ERP), which is a form of CBT.
  • Imaginal Exposure. ...
  • Habit Reversal Training. ...
  • Cognitive Therapy. ...

Does OCD "need" to be treated?

Treatment. Obsessive-compulsive disorder treatment may not result in a cure, but it can help bring symptoms under control so that they don't rule your daily life. Depending on the severity of OCD, some people may need long-term, ongoing or more intensive treatment. The two main treatments for OCD are psychotherapy and medications. Often, treatment is most effective with a combination of these.

What is OCD in children?

What are the limitations of pediatric OCD research?

What is exposure based therapy?

How does OCD affect children?

Is OCD a heterogeneous disorder?

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How was OCD first treated?

When the symptoms became disruptive, people with OCD were sometimes placed in asylums, often against their will. Toward the end of the 1800s, OCD was starting to be treated with more humane methods, which mostly included forms of psychotherapy and talk therapy that were popular in Freudian psychology.

Which group of medications has been found to be most effective in treating OCD?

The types of medication that research has shown to be most effective for OCD are a type of drug called a Serotonin Reuptake Inhibitor (SRI), which are traditionally used as an antidepressants, but also help to address OCD symptoms.

What were the main results of the Pediatric OCD treatment Study and the Pediatric OCD treatment Study II?

Conclusions: Among patients aged 7 to 17 years with OCD and partial response to SRI use, the addition of CBT to medication management compared with medication management alone resulted in a significantly greater response rate, whereas augmentation of medication management with the addition of instructions in CBT did ...

What is the most popular treatment for OCD?

More specifically, the most effective treatments are a type of CBT called Exposure and Response Prevention (ERP), which has the strongest evidence supporting its use in the treatment of OCD, and/or a class of medications called serotonin reuptake inhibitors, or SRIs.

Which of the following medications was the first effective pharmacological treatment for OCD?

Clomipramine. The tricyclic antidepressant clomipramine was the first agent shown clearly to be beneficial in patients with OCD [4]; it was approved by the FDA for the treatment of OCD in 1989. Of the tricyclics, clomipramine is the most potent inhibitor of serotonin reuptake.

What is CBT therapy for OCD?

Cognitive-behavior therapy is a type of treatment that helps individuals cope with and change problematic thoughts, behaviors, and emotions. The treatment you are beginning is a specialized type of cognitive-behavior therapy for obsessive-compulsive disorder (OCD) called Exposure and Ritual Prevention.

How do you get treated for OCD?

The 2013 APA Practice Guideline for the Treatment of Patients with Obsessive Compulsive Disorder recommends beginning OCD treatment with a type of cognitive behavior therapy (CBT) called exposure and response prevention (ERP), which has the strongest evidence supporting its use in the treatment of OCD.

How is OCD treated in autism?

Cognitive behavioral therapy (CBT) is typically the most helpful treatment for OCD, and it is also used in treating OCD with autism. This behavioral intervention relies on uncovering potential triggers and learning how to manage them.

What is OCD in children?

Pediatric obsessive-compulsive disorder (OCD) is a chronic, impairing condition associated with high levels of family accommodation. Research shows that involving families in treatment helps shape outcomes for youth with OCD. Specifically, the way a family reacts and copes when faced with OCD symptoms plays an important role in the course and maintenance of the disorder. In this chapter, we provide a brief overview of specific family factors that are associated with child and adolescent OCD, and we document their links to CBT outcomes. We then detail additional skills focusing on self-soothing, resolving broader family conflicts, and troubleshooting around barriers to successful treatment.

What are the limitations of pediatric OCD research?

One important limitation in pediatric OCD research has been the relative cultural homogeneity in research samples. In the United States, for example, the majority of participants in the largest treatment trials have identified as White-Caucasian ( Wetterneck et al., 2012; Williams et al., 2010 ). Further, large-scale genetic studies have been conducted predominantly with individuals from the United States or Scandinavian countries ( Arnold et al., 2018 ). Epidemiologic research, however, has generally not identified racial or class disparities in the prevalence of OCD, however ( Himle et al., 2008 ), though it is interesting to note relatively lower prevalence estimates in European countries compared with South or North American countries reviewed in this article ( Alvarenga et al., 2015a, 2015b; Barzilay et al., 2019; Canals et al., 2012; Politis et al., 2017; Vivan et al., 2014 ). Research is beginning to focus on understanding barriers and differences in clinical presentation among African Americans compared with European Americans; for example, following a small number of studies on African Americans with OCD, it has been proposed that African American children with OCD may be less likely to receive help or participate in randomized controlled trials due to less access to, greater stigma toward, or less trust in mental health treatment ( Williams and Jahn, 2017 ). One study found minimal differences in clinical presentation, comorbidity, or treatment outcome among White and non-White children and adolescents with OCD ( de la Cruz et al., 2015 ), though there may be important clinical differences between these groups that could be identified by studying OCD-relevant constructs that may differ across specific cultures; for example, Williams and Jahn (2017) point out that African American parents are more likely to use authoritarian parenting style that may protect against excessive parental accommodation, though this is an empirical question that has not been tested to date. As investigators continue to advance research on OCD, it will be critical to place greater emphasis on including diverse samples in order to better understand how sociocultural factors influence the presentation, assessment, and treatment of pediatric OCD.

What is exposure based therapy?

Exposure-based cognitive behavioral therapy (CBT) is an effective first-line treatment for anxiety disorders and obsessive-compulsive disorder (OCD) in youth. The chapter provides an overview of the evidence base for CBT in youth anxiety and OCD, including examples of well-studied interventions: Coping Cat, Cool Kids, the Pediatric OCD Treatment Study, and the Nordic Long-Term OCD Treatment Study. It then examines the efficacy of key delivery format adaptations such as remote treatments, treatment intensity, and group versus individual therapy. Finally, it presents research on the impact of important clinical characteristics on CBT outcome, such as family factors, disorder-specific issues, and comorbid disorders. Although further research is needed regarding predictors of treatment outcome and how to maximize efficiency of care, there is strong evidence to support the use of exposure-based CBT for youth anxiety and OCD.

How does OCD affect children?

Pediatric OCD can disrupt normal development and cause significant academic impairment, social difficulties, distress, and poor quality of life. Prior to the emergence of clomipramine in the 1960s, OCD was believed to be a lifelong untreatable condition with a poor prognosis ( Arumugham & Reddy, 2013 ). However, it is now clear that many children with OCD will remit or develop subclinical symptoms over time ( Geller et al., 1998 ). Approximately 40% of treated children with OCD have a remission of their symptoms over the long term ( Arumugham & Reddy, 2013; Bloch et al., 2009; Stewart et al., 2004 ).

Is OCD a heterogeneous disorder?

OCD is a highly heterogeneous condition, encompassing a wide range of possible obsessions and compulsions. Factor analytic studies have found that paediatric OCD symptoms fall into at least four dimensions, namely, hoarding/checking, taboo obsessions, contamination/cleaning, and symmetry/ordering ( Mataix-Cols, do Rosario-Campos, & Leckman, 2005 ). Several studies have examined the temporary stability of OCD symptoms in young people. The main finding from these investigations is that it is relatively common for OCD symptoms to change over time within symptom dimension but changes between symptoms dimensions are rare ( Delorme et al., 2006; Fernandez de la Cruz et al., 2013; Rettew, Swedo, Leonard, Lenane, & Rapoport, 1992 ). Nevertheless, frequently changing compulsions are commonly reported by clinicians as being an obstacle in CBT for OCD ( Keleher, Jassi, & Krebs, in press ). The therapist might find it hard to construct or adhere to a hierarchy, and treatment can feel like a constant process of firefighting of new symptoms.

What is the best treatment for pediatric OCD?

Medication for Pediatric OCD. The best treatment for pediatric OCD includes both medication and a type of cognitive behavioral therapy (CBT) called exposure and response prevention (ERP) therapy. Medication should only be considered when there are moderate to severe OCD symptoms. Click here to learn more about ERP and therapeutic approaches used ...

How long does it take for OCD to work?

All OCD medications work slowly. It is important to not give up on a medication until it has been taken at the right dose for 10 to 12 weeks. Studies have also shown that improvement of childhood OCD can continue for at least a year after starting medication.

How long does OCD last after stopping?

Many doctors suggest that OCD treatment should continue for at least one year even after symptoms have stopped. Unfortunately, OCD drugs do not “cure” the illness. When medication is stopped, symptoms often return within a few weeks to months, especially if your child has not received ERP therapy.

What is the first medication that a doctor will try?

Antidepressants are usually the first kind of medication that a doctor will try. Your doctor might refer to these medications as “serotonin reuptake inhibitors” (SRIs). SRIs include: Citalopram (Celexa®) Escitalopram (Lexapro®) Fluvoxamine (Luvox®) Fluoxetine (Prozac®) Paroxetine (Paxil®) Sertraline (Zoloft®)

Does ERP help with OCD?

Both ERP and medication effectively treat OCD in children and adolescents. Their use is supported by the treatment guidelines of the American Psychiatric Association (APA) and the American Academy of Child and Adolescent Psychiatry (AACAP). Medications should only be considered when there are moderate to severe OCD symptoms and when exposure ...

Can OCD medication be used to treat a child?

OCD medications control and decrease symptoms, but do not “cure” the disorder. OCD is usually well controlled when proper treatment is in place. Symptoms often return when the child stops taking the medication, especially if he or she has not received ERP therapy.

Can OCD pills be used for depression?

However, OCD symptoms often require the use of higher, adult-sized doses. This is important since most doctors are used to using lower doses for treating depression and anxiety, but that may not work for OCD. If the child has difficulty swallowing pills, a liquid or other version may be available.

How many children have OCD?

Childhood-onset obsessive-compulsive disorder (OCD) affects 1–2% of children and adolescents. Characterized by recurrent obsessions and compulsions, the illness can create severe distress as it interferes with daily life. A treatment was needed to effectively control symptoms in the pediatric population without concomitant adverse events.

When was clomipramine approved?

The team's research was the first to demonstrate a drug’s effectiveness in treating children with obsessive-compulsive disorder, which led the way for an eventual FDA approval of clomipramine in 1998 to help improve pediatric patients’ lives.

What is OCD in children?

Paediatric obsessive-compulsive disorder (OCD) is a chronic condition often associated with severe disruptions of family functioning, impairment of peer relationships and academic performance. Mean age of onset of juvenile OCD is 10.3 years; however, reports on young children with OCD show that the disorder can manifest itself at an earlier age. Both an earlier age of onset and a longer duration of illness have been associated with increased persistence of OCD. There seems to be difficulty for health professionals to recognize and diagnose OCD in young children appropriately, which in turn may prolong the interval between help seeking and receiving an adequate diagnosis and treatment. The objective of this study is to enhance knowledge about the clinical presentation, diagnosis and possible treatment of OCD in very young children.

How old is too old to have OCD?

Mean age of onset of OCD symptoms was 3 years, with some OCD symptoms appearing as early as 18 months of age. All subjects had at least one comorbid disorder; the most frequent comorbidity was an anxiety disorder, and boys exhibited more comorbid diagnoses than girls.

What was the diagnosis of patient 5?

She had one elder brother and lived with both parents. At the age of 1 year, patient 5 was diagnosed with a benign brain tumor (astrocytoma). The tumor had been removed for 90% by surgery; the remaining tumor was treated with chemotherapy.

Can OCD relapse?

OCD is known to be a chronic condition. Therefore, in spite of treatment success, relapse might occur. However, as our treatment approach mainly targeted family accommodation, parents will hopefully react with less accommodation, should a new episode of OCD occur.

Can a streptococcal infection cause OCD?

One possible, but rare and debated cause of OCD are streptococcal infections, often referred to as PANS [ 33 ]. However, in none of the cases parents reported an abrupt and sudden onset of OCD symptoms after an infection. Instead, symptoms seem to have developed gradually over a period of several months or even years.

Does early OCD shorten the time between symptoms?

Disseminating knowledge about the clinical presentation, diagnosis and treatment of early OCD may shorten the long delay between first OCD symptoms and disease-specific treatment that is reported as main predictor for persistent OCD.

How to treat OCD in children?

Pediatric OCD is best treated by a licensed mental health professional using a type of cognitive behavior therapy (CBT) called exposure and response prevention (ERP): 1 In ERP, kids learn to face their fears (exposure) without giving in to compulsions (response prevention). 2 A licensed mental health professional (such as a psychologist, social worker, or counselor) will guide them through this process, and children will learn that they can allow the obsessions and anxiety to come and go without the need for their compulsions or rituals. Click here for help finding the right therapist for your child/teen.

What is the first line treatment for OCD?

Taken together, ERP and medication are considered the “first-line” treatments for OCD. In other words, START HERE! About 70 percent of people will benefit from ERP and/or medication for their OCD.

How long are summer camps for OCD?

Summer Programs and Camps#N#Many intensive treatment programs now offer summer “camps” for children and teens with OCD. These programs vary in approach and style, but most are about a week long, and range from traditional “sleep-away” camps to daytime camps where children sleep at home or stay with family nearby. Click here to learn more.

What is OCD in children?

Pediatric obsessive-compulsive disorder (OCD) is a chronic, impairing condition associated with high levels of family accommodation. Research shows that involving families in treatment helps shape outcomes for youth with OCD. Specifically, the way a family reacts and copes when faced with OCD symptoms plays an important role in the course and maintenance of the disorder. In this chapter, we provide a brief overview of specific family factors that are associated with child and adolescent OCD, and we document their links to CBT outcomes. We then detail additional skills focusing on self-soothing, resolving broader family conflicts, and troubleshooting around barriers to successful treatment.

What are the limitations of pediatric OCD research?

One important limitation in pediatric OCD research has been the relative cultural homogeneity in research samples. In the United States, for example, the majority of participants in the largest treatment trials have identified as White-Caucasian ( Wetterneck et al., 2012; Williams et al., 2010 ). Further, large-scale genetic studies have been conducted predominantly with individuals from the United States or Scandinavian countries ( Arnold et al., 2018 ). Epidemiologic research, however, has generally not identified racial or class disparities in the prevalence of OCD, however ( Himle et al., 2008 ), though it is interesting to note relatively lower prevalence estimates in European countries compared with South or North American countries reviewed in this article ( Alvarenga et al., 2015a, 2015b; Barzilay et al., 2019; Canals et al., 2012; Politis et al., 2017; Vivan et al., 2014 ). Research is beginning to focus on understanding barriers and differences in clinical presentation among African Americans compared with European Americans; for example, following a small number of studies on African Americans with OCD, it has been proposed that African American children with OCD may be less likely to receive help or participate in randomized controlled trials due to less access to, greater stigma toward, or less trust in mental health treatment ( Williams and Jahn, 2017 ). One study found minimal differences in clinical presentation, comorbidity, or treatment outcome among White and non-White children and adolescents with OCD ( de la Cruz et al., 2015 ), though there may be important clinical differences between these groups that could be identified by studying OCD-relevant constructs that may differ across specific cultures; for example, Williams and Jahn (2017) point out that African American parents are more likely to use authoritarian parenting style that may protect against excessive parental accommodation, though this is an empirical question that has not been tested to date. As investigators continue to advance research on OCD, it will be critical to place greater emphasis on including diverse samples in order to better understand how sociocultural factors influence the presentation, assessment, and treatment of pediatric OCD.

What is exposure based therapy?

Exposure-based cognitive behavioral therapy (CBT) is an effective first-line treatment for anxiety disorders and obsessive-compulsive disorder (OCD) in youth. The chapter provides an overview of the evidence base for CBT in youth anxiety and OCD, including examples of well-studied interventions: Coping Cat, Cool Kids, the Pediatric OCD Treatment Study, and the Nordic Long-Term OCD Treatment Study. It then examines the efficacy of key delivery format adaptations such as remote treatments, treatment intensity, and group versus individual therapy. Finally, it presents research on the impact of important clinical characteristics on CBT outcome, such as family factors, disorder-specific issues, and comorbid disorders. Although further research is needed regarding predictors of treatment outcome and how to maximize efficiency of care, there is strong evidence to support the use of exposure-based CBT for youth anxiety and OCD.

How does OCD affect children?

Pediatric OCD can disrupt normal development and cause significant academic impairment, social difficulties, distress, and poor quality of life. Prior to the emergence of clomipramine in the 1960s, OCD was believed to be a lifelong untreatable condition with a poor prognosis ( Arumugham & Reddy, 2013 ). However, it is now clear that many children with OCD will remit or develop subclinical symptoms over time ( Geller et al., 1998 ). Approximately 40% of treated children with OCD have a remission of their symptoms over the long term ( Arumugham & Reddy, 2013; Bloch et al., 2009; Stewart et al., 2004 ).

Is OCD a heterogeneous disorder?

OCD is a highly heterogeneous condition, encompassing a wide range of possible obsessions and compulsions. Factor analytic studies have found that paediatric OCD symptoms fall into at least four dimensions, namely, hoarding/checking, taboo obsessions, contamination/cleaning, and symmetry/ordering ( Mataix-Cols, do Rosario-Campos, & Leckman, 2005 ). Several studies have examined the temporary stability of OCD symptoms in young people. The main finding from these investigations is that it is relatively common for OCD symptoms to change over time within symptom dimension but changes between symptoms dimensions are rare ( Delorme et al., 2006; Fernandez de la Cruz et al., 2013; Rettew, Swedo, Leonard, Lenane, & Rapoport, 1992 ). Nevertheless, frequently changing compulsions are commonly reported by clinicians as being an obstacle in CBT for OCD ( Keleher, Jassi, & Krebs, in press ). The therapist might find it hard to construct or adhere to a hierarchy, and treatment can feel like a constant process of firefighting of new symptoms.

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