Treatment FAQ

what treatment for bladder cancer

by Prof. Jessy Oberbrunner PhD Published 2 years ago Updated 2 years ago
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Bladder cancer treatment may include: Surgery, to remove the cancer cells. Chemotherapy in the bladder (intravesical chemotherapy), to treat cancers that are confined to the lining of the bladder but have a high risk of recurrence or progression to a higher stage.May 17, 2021

Medication

Chemo (with or without radiation) is typically the first treatment when bladder cancer has spread to distant parts of the body (M1). After this treatment the cancer is rechecked. If it looks like it's gone, a boost of radiation to the bladder may be given or cystectomy might be done.

Procedures

Depending on the stage of the cancer and other factors, treatment options for people with bladder cancer can include: Bladder Cancer Surgery Intravesical Therapy for Bladder Cancer Chemotherapy for Bladder Cancer Radiation Therapy for Bladder Cancer Immunotherapy for Bladder Cancer Targeted Therapy Drugs for Bladder Cancer

Therapy

The most common chemotherapeutic drug used in bladder cancer is cisplatin. Immunotherapy Immunotherapy is a cancer treatment approach that uses drugs and vaccines to harness the immune system’s natural ability to fight cancer, in the same way it fights off infections.

Nutrition

Sep 28, 2021 · Chemotherapy drugs commonly used for bladder cancer include Mutamycin (mitomycin), Gemzar (gemcitabine), or Valstar (valrubicin). 1 Radiation therapy Immunotherapy with a drug such as Opdivo (nivolumab) System-wide chemotherapy Targeted therapy Clinical trials Summary BCG treatment is a form of immunotherapy for non-muscle invasive bladder …

What is the best cure for bladder cancer?

Bacillus Calmette-Guerin or BCG is the most common intravesical immunotherapy for treating early-stage bladder cancer. It's used to help keep the cancer from growing and to help keep it from coming back. BCG is a germ that's related to the one that causes tuberculosis (TB), but it doesn’t usually cause serious disease.

What is the newest treatment for bladder cancer?

Feb 13, 2020 · In the case of BCG infection, antituberculosis drug treatment is prescribed, which consists of four daily antimicrobials for four months and two antimicrobials for two more months. When serious adverse events appear, intravesical instillations of BCG are stopped, and these patients are deprived of this efficacious treatment.

What is bladder cancer, and how is it treated?

Jan 17, 2013 · Classification. Classification of bladder cancer is important to determine the appropriate treatment strategy and predict outcomes. The WHO grading of bladder cancer has changed, with the 2004 grading system incorporating a range of histologic descriptions such as urothelial papilloma (completely benign lesion), papillary urothelial neoplasm of low malignant …

How do I care for someone with bladder cancer?

For other people, bladder cancer might never go away completely or might come back in another part of the body. Some people may get regular treatment with chemotherapy , immunotherapy, or other treatments to try to keep the cancer in check. Learning to live with cancer that doesn't go away can be difficult and very stressful.

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What is the best treatment for bladder cancer?

Transurethral resection (TURBT) is often done first to find out how far the cancer has grown into the bladder wall. Chemotherapy followed by radical cystectomy (removal of the bladder and nearby lymph nodes) is then the standard treatment. Partial cystectomy is rarely an option for stage III cancers.Sep 20, 2021

Is bladder cancer very curable?

The stage of the cancer (whether it is superficial or invasive bladder cancer, and whether it has spread to other places in the body). Bladder cancer in the early stages can often be cured.Mar 25, 2022

Does bladder cancer spread quickly?

It is an early stage cancer but is always high grade. This means it can grow quickly and might spread. If you have bladder carcinoma in situ your doctor will start treatment straight away.

What is the latest treatment for bladder cancer?

Advanced and metastatic bladder cancer treatment A notable new FDA approval in December 2019 was enfortumab vedotin (Padcev), approved for advanced bladder cancer patients who have not responded to chemotherapy or immune checkpoint drugs.

What are the warning signs of bladder cancer?

Bladder Cancer: Symptoms and SignsBlood or blood clots in the urine.Pain or burning sensation during urination.Frequent urination.Feeling the need to urinate many times throughout the night.Feeling the need to urinate, but not being able to pass urine.Lower back pain on 1 side of the body.

What is the main cause of bladder cancer?

Smoking is the single biggest risk factor for bladder cancer. This is because tobacco contains cancer-causing (carcinogenic) chemicals. If you smoke for many years, these chemicals pass into your bloodstream and are filtered by the kidneys into your urine.

Where does bladder cancer usually spread to first?

Bladder cancer can spread this way. If it does, it usually first spreads to the lymph nodes in the pelvis around the bladder (called perivesicular lymph nodes). From there, it can spread to lymph nodes that are close to major blood vessels that run into the leg and pelvis.7 days ago

Does bladder cancer show up on a CT scan?

Computed tomography (CT) scan It can provide detailed information about the size, shape, and position of any tumors in the urinary tract, including the bladder. It can also help show enlarged lymph nodes that might contain cancer, as well as other organs in the abdomen (belly) and pelvis.Jan 30, 2019

Can you live without a bladder?

With enough time, you should be able to do almost everything you did before. Even if you now use a urostomy bag (to collect your urine), you can go back to work, exercise, and swim. People might not even notice you until you tell them.Oct 28, 2021

Which of the following is usually the first symptom of bladder cancer?

For most people, the first symptom of bladder cancer is blood in the urine, also called hematuria. Sometimes the blood is visible, prompting the patient to visit a doctor.

How long do you have to wear a catheter after bladder surgery?

Sometimes the catheter must stay in place for a while after you go home. The blood in your urine will slowly clear and then the catheter can come out. This is normally about 1 to 3 days after surgery.

How long does it take to recover from bladder cancer surgery?

It will take 6 weeks from the date of surgery to fully recover from your operation. This can be divided into two parts -- the first 2 weeks and the last 4 weeks. During the first 2 weeks from the date of your surgery, it is important to be "a person of leisure".

Which Treatments Are Used For Bladder Cancer?

Depending on the stage of the cancer and other factors, treatment options for people with bladder cancer can include: 1. Surgery 2. Intravesical th...

Which Doctors Treat Bladder Cancer?

Depending on your options, you can have different types of doctors on your treatment team. The types of doctors who treat bladder cancers include:...

Making Treatment Decisions

It’s important to discuss all of your treatment options, including their goals and possible side effects, with your doctors to help make the decisi...

Help Getting Through Treatment

Your cancer care team will be your first source of information and support, but there are other resources for help when you need it. Hospital- or c...

What is the treatment for bladder cancer?

Depending on the stage of the cancer and other factors, treatment options for people with bladder cancer can include: Bladder Cancer Surgery. Intravesical Therapy for Bladder Cancer. Chemotherapy for Bladder Cancer. Radiation Therapy for Bladder Cancer. Immunotherapy for Bladder Cancer. Targeted Therapy Drugs for Bladder Cancer.

What are the things to consider when considering cancer treatment?

Some important things to consider include: Your age and expected life span. Any other serious health conditions you have. The stage and grade of your cancer. The likelihood that treatment will cure your cancer (or help in some other way) Your feelings about the possible side effects from treatment.

What kind of doctor treats cancer?

Based on your treatment options, you might have different types of doctors on your treatment team. These doctors could include: 1 Urologists: surgeons who specialize in treating diseases of the urinary system and male reproductive system 2 Radiation oncologists: doctors who treat cancer with radiation therapy 3 Medical oncologists: doctors who treat cancer with medicines such as chemotherapy and immunotherapy

What do people with cancer need?

People with cancer need support and information, no matter what stage of illness they may be in. Knowing all of your options and finding the resources you need will help you make informed decisions about your care.

What are the things to consider when making a treatment decision?

Some important things to consider include: Your age and expected life span.

What are the services offered by the American Cancer Society?

These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. The American Cancer Society also has programs and services – including rides to treatment, lodging, and more – to help you get through treatment.

Is treatment information given here official policy of the American Cancer Society?

The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

What is bladder cancer?

Bladder cancer is a disease in which malignant (cancer) cells form in the tissues of the bladder. The bladder is a hollow organ in the lower part of the abdomen. It is shaped like a small balloon and has a muscular wall that allows it to get larger or smaller to store urine made by the kidneys.

What is it called when you have cancer in your bladder?

Cancer that is in the lining of the bladder is called superficial bladder cancer. Cancer that has spread through the lining of the bladder and invades the muscle wall of the bladder or has spread to nearby organs and lymph nodes is called invasive bladder cancer. See the following PDQ summaries for more information:

What type of cancer begins in squamous cells?

Squamous cell carcinoma: Cancer that begins in squamous cells (thin, flat cells lining the inside of the bladder). Cancer may form after long-term infection or irritation. Adenocarcinoma: Cancer that begins in glandular cells that are found in the lining of the bladder.

Where does bladder cancer start?

Most bladder cancers begin in the transitional cells. Transitional cell carcinoma can be low- grade or high-grade: Low-grade transitional cell carcinoma often recurs (comes back) after treatment, but rarely spreads into the muscle layer of the bladder or to other parts of the body.

Can chemo be given in the bladder?

For bladder cancer, regional chemotherapy may be intravesical (put into the bladder through a tube inserted into the urethra). The way the chemotherapy is given depends on the type and stage of the cancer being treated. Combination chemotherapy is treatment using more than one anticancer drug.

Which type of cancer begins in the innermost tissue layer of the bladder?

These cancers are named for the type of cells that become malignant (cancerous): Transitional cell carcinoma: Cancer that begins in cells in the innermost tissue layer of the bladder. These cells are able to stretch when the bladder is full and shrink when it is emptied.

Is metastatic bladder cancer the same as primary cancer?

The metastatic tumor is the same type of cancer as the primary tumor. For example, if bladder cancer spreads to the bone, the cancer cells in the bone are actually bladder cancer cells. The disease is metastatic bladder cancer, not bone cancer. YouTube. National Cancer Institute.

How does radiation therapy help bladder cancer?

Radiation therapy. Radiation therapy uses beams of powerful energy, such as X-rays and protons, to destroy the cancer cells. Radiation therapy for bladder cancer usually is delivered from a machine that moves around your body, directing the energy beams to precise points.

How to diagnose bladder cancer?

Tests and procedures used to diagnose bladder cancer may include: Using a scope to examine the inside of your bladder (cystoscopy). To perform cystoscopy, your doctor inserts a small , narrow tube (cystoscope) through your urethra. The cystoscope has a lens that allows your doctor to see the inside of your urethra and bladder, ...

What is a cystoscope?

Cystoscopy allows your doctor to view your lower urinary tract to look for abnormalities, such as a bladder stone. Surgical tools can be passed through the cystoscope to treat certain urinary tract conditions.

How to get a follow up on bladder cancer?

Get a schedule of follow-up tests and go to each appointment. When you finish bladder cancer treatment, ask your doctor to create a personalized schedule of follow- up tests. Before each follow-up cystoscopy exam, expect to have some anxiety. You may fear that cancer has come back or worry about the uncomfortable exam.

What is the procedure called when you remove a sample of tissue for testing?

Removing a sample of tissue for testing (biopsy). During cystoscopy, your doctor may pass a special tool through the scope and into your bladder to collect a cell sample (biopsy) for testing. This procedure is sometimes called transurethral resection of bladder tumor (TURBT). TURBT can also be used to treat bladder cancer.

What is a low grade bladder cancer?

Low-grade bladder cancer. This type of cancer has cells that are closer in appearance and organization to normal cells (well differentiated). A low-grade tumor usually grows more slowly and is less likely to invade the muscular wall of the bladder than is a high-grade tumor. High-grade bladder cancer.

What tests can be done to determine if you have bladder cancer?

Tests may include: CT scan.

What is the treatment for bladder cancer?

Immunotherapy is a cancer treatment approach that uses drugs and vaccines to harness the immune system’s natural ability to fight cancer, in the same way it fights off infections. The approach is still being researched and there is a lot left to learn, but clinical studies have shown that immunotherapy holds a lot of promise in its ability to treat a wide range of malignancies, including some types of bladder cancer.

What is the procedure to remove a bladder tumor?

Cystectomy (Bladder Removal) Surgery. When bladder cancer tumors completely invade the bladder’s muscular wall, the standard of care is to perform bladder removal surgery. Typically, complete removal of the bladder ( radical cystectomy) is required. Partial cystectomy is rare because the requirements are that the tumor is easily accessible ...

What is the procedure called when a camera is passed through the urethra?

Cystoscopy is an outpatient procedure during which a thin, lighted tube with a camera is passed through the urethra into the bladder, allowing your doctor to see the inside of the bladder.

How does chemotherapy work?

Chemotherapy uses chemical agents to interfere with replication and other normal functions of cells, resulting in tumor shrinkage or cancer cell death . The use of two or more chemotherapy drugs together has been found to be more effective than a single drug alone. There are several types of chemotherapy.

What percentage of bladder cancer is superficial?

Bladder Cancer Liver Gallbladder and Pancreas Urological Conditions Cancer. Over 75 percent of bladder cancers remain confined to the lining of the bladder and do not invade the bladder wall. These are called nonmuscle-invasive bladder cancer, or superficial bladder cancer, and when managed well, they are associated with excellent prognoses.

What is a TUR procedure?

Transurethral resection (TUR) is an endoscopic or scope procedure that does not involve making an incision in the body. Drug therapy after TUR is commonly prescribed for patients with large, multiple or high-grade tumors.

What is radiation therapy?

Radiation therapy, used to treat cancer, is a special high-energy X-ray that is more powerful than the X-rays used for imaging studies. Radiation therapy is planned and executed in a way to kill cancer cells or alter their ability to reproduce, while the surrounding healthy cells are minimally affected.

The Early-Stage Bladder Cancer Treatment

Jennifer Welsh is a Connecticut-based science writer and editor with over ten years of experience under her belt. She’s previously worked and written for WIRED Science, The Scientist, Discover Magazine, LiveScience, and Business Insider.

Who Can Use BCG?

BCG is a treatment for early-stage bladder cancer that has not yet invaded the muscle of the bladder wall. Called non-muscle invasive bladder cancers (NMIBCs) or in situ bladder cancers, these account for about half of all bladder cancers. 3

What to Expect During BCG Treatment

First, make sure you haven’t had any fluids for four hours before the treatment. Right before you go into the treatment room your doctor or nurse will have you empty your bladder. 2

How to Prepare

To prepare for the BCG treatment, your doctor will likely have you undergo surgery to remove any visible cancer in the bladder. The surgery is called transurethral resection of bladder tumor (TURBT) and is usually done about two weeks before BCG therapy.

When to See a Doctor

There are a few side effects that can be especially dangerous, so make sure to talk to your doctor if you notice that you: 2

Other Treatments for Bladder Cancer

For many early-stage bladder cancers, BCG is the best option for treatment. Other treatments for bladder cancer include:

Summary

BCG treatment is a form of immunotherapy for non-muscle invasive bladder cancer. It is administered into the bladder through a catheter. It then activates the body's immune system to attack the cancer cells.

What is the best treatment for bladder cancer?

Immunotherapy causes the body’s own immune system to attack the cancer cells. Bacillus Calmette-Guerin or BCG is the most common intravesical immunotherapy for treating early-stage bladder cancer. It's used to help keep the cancer from growing and to help keep it from coming back.

What is the treatment for low grade bladder cancer?

Low-risk non-invasive (low-grade) bladder cancers grow slowly. They may be treated with 1 dose of intravesical chemo after TURBT. It's used to help keep the cancer from coming back. Intravesical chemotherapy or immunotherapy may used for intermediate non-invasive bladder cancers.

How long after a turbt can you get a tumor?

After TURBT. Intravesical therapy is commonly used after transurethral resection of bladder tumor (TURBT). It's often done within 24 hours of the TURBT procedure. Some experts say it should be done within 6 hours. The goal is to kill any cancer cells that may be left in the bladder.

What is non invasive bladder cancer?

They may be called non-invasive (stage 0), or minimally invasive (stage I) bladder cancers. They have not spread into deeper layers on the bladder wall muscles or to other parts of the body.

How long does bladder cancer treatment last?

This is called induction therapy. After a 4- to 6-week break, maintenance treatments are then done for at least 1 year. High-risk non-invasive bladder cancers might be fast-growing (high-grade), big, or there may be more than 1 tumor.

How long does a drug stay in your bladder?

The drug is put in through a soft catheter that's put into your bladder through your urethra. The drug stays in your bladder for up to 2 hours. This way, the drug can affect the cells lining the inside ...

Can you get cancer from a bladder lining?

This means that any cancer cells outside of the bladder lining, including those that have grown deeply into the bladder wall, are not treated by intravesical therapy. Drugs put into the bladder also can’t reach cancer cells in the kidneys, ureters, and urethra, or those that have spread to other parts of the body.

What to do if you have bladder cancer?

If you have (or have had) bladder cancer, you probably want to know if there are things you can do that might lower your risk of the cancer growing or coming back, such as exercising, eating a certain type of diet, or taking nutritional supplements. Unfortunately, it’s not yet clear if there are things you can do that will help.

What tests are done to see if bladder cancer is growing back?

Your follow-up plan might include urine tests, physical exams, imaging tests (like x-rays, MRI, or CT scans), and blood tests. These doctor visits and tests will be done less often as time goes by and no new cancers are found.

How often should you have a cystoscopy?

If your bladder hasn’t been removed, regular cystoscopy exams will also be done every 3 months for at least the first 2 years. If you have a urinary diversion, you will be checked for signs of infection and changes in the health of your kidneys. Urine tests, blood tests, and x-rays might be used to do this.

What happens if you have a radical cystectomy and a urostomy?

If you had a radical cystectomy and now have a urostomy, you might worry even about everyday activities at first. You might have to alter some of your daily (and nightly) routines because of changes in how you urinate. Other issues such as having sex might also cause concerns (see below).

Can bladder cancer affect your sex life?

Bladder cancer treatment can often affect your sex life. (See Bladder Cancer Surgery for more on this.) Learning to be comfortable with your body during and after bladder cancer treatment is a personal journey, one that's different for everyone. Information and support can help you cope with these changes over time.

Does bladder cancer go away?

For other people, bladder cancer might never go away completely or might come back in another part of the body. Some people may get regular treatment with chemotherapy , immunotherapy, or other treatments to try to keep the cancer in check. Learning to live with cancer that doesn't go away can be difficult and very stressful.

Can bladder cancer be removed?

Living as a Bladder Cancer Survivor. For some people with bladder cancer , treatment can remove or destroy the cancer. The end of treatment can be both stressful and exciting. You may be relieved to finish treatment, but find it hard not to worry about cancer coming back. This is very common if you’ve had cancer.

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatments include surgery, chemotherapy, and biological therapy.
Medication

Immunotherapy: This therapy helps boost your immune system fight against the cancerous cells.

Atezolizumab . Durvalumab . Avelumab


Chemotherapy: Injection of cancer-fighting medications into the bladder through a catheter to kill the harmful cells.

Gemcitabine/Cisplatin . Methotrexate/ Vinblastine/Doxorubicin/Cisplatin (called MVAC) . Cisplatin/ Methotrexate/Vinblastine (called CMV) . Carboplatin/Paclitaxel . Docetaxel

Procedures

Transurethral resection of bladder tumor (TURBT): An instrument called a resectoscope is inserted into the bladder through the urethra which is used to remove abnormal tissues or tumors.

Cystectomy: Removal of a part of bladder is called as partial cystectomy or complete bladder removal which is called as radical cystectomy.

Therapy

Radiation therapy:High-energy radiation is used to kill the cancer cells.

Nutrition

Foods to eat:

  • Focus on starchy carbohydrates such as bread, pasta, rice or potatoes
  • Whole grains are highly recommended
  • Eat a variety of fruit and vegetables daily
  • Include lean protein such as meat, fish, eggs, beans or pulses
  • Have milk and cheese

Foods to avoid:

  • Eggs, total fat, butter
  • Soft drinks, caffeine, chlorinated surface water, sugar

Specialist to consult

Urologist
Specializes in the urinary tract disease.
Oncologist
Specializes in the diagnosis and treatment of cancer.

Preparing For Your Appointment

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