Treatment FAQ

what to expect with larynx cancer treatment

by Prof. Modesta Cartwright PhD Published 2 years ago Updated 2 years ago
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Cancers of the larynx or hypopharynx and their treatments can sometimes cause problems such as trouble swallowing, dry mouth, or even loss of teeth. This can make it hard to eat, which can lead to weight loss and weakness from poor nutrition.

The larynx (voice box) often needs to be removed as well. People who have a high chance of the cancer returning (based on what's found during surgery) might then be treated with radiation or chemotherapy combined with radiation (chemoradiation). Some patients with small tumors may get radiation as their main treatment.Jan 21, 2021

Full Answer

What happens after treatment for laryngeal cancer?

After treatment for laryngeal cancer, frequent and careful follow-up is important. After laryngeal cancer has been diagnosed, tests are done to find out if cancer cells have spread within the larynx or to other parts of the body.

What is the prognosis of advanced larynx cancer?

Standard treatment for patients with advanced laryngeal cancer has historically consisted of total laryngectomy, often combined with modified neck dissection. When metastatic cancer is present in the lymphatics of the neck, surgery is combined with radiation therapy. Five-year cure rates vary from 40-60%.

What are the treatment options for local recurrence of larynx cancer?

Local recurrence in people who have already had limited surgery such as partial laryngectomy, can often be treated with more extensive surgery (such as a total laryngectomy). This may be followed by radiation therapy or chemoradiation (radiation and chemo are given at the same time).

What are larynx cancers?

Written by Gregory T. Wolf, M.D. Cancers arising in the larynx (voice box) are devastating malignancies that account for roughly 200,000 deaths annually worldwide. Although this only represents 2-5% of all malignancies, these cancers have special importance because of their significant effects on voice, swallowing and quality of life.

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What is the prognosis for malignant tumors of the larynx?

For laryngeal cancers, survival rates differ based on which part of the larynx the cancer started in (supraglottis, glottis, or subglottis)....Supraglottis (part of the larynx above the vocal cords)SEER stage5-year relative survival rateLocalized62%Regional47%Distant30%All SEER stages combined46%Mar 1, 2022

Can you talk after laryngeal cancer?

While your throat heals, you'll need to be fed through a tube that's passed through your nose and into your stomach. If you have had all of your larynx removed (total laryngectomy), you will not be able to speak normally, because you'll no longer have vocal cords.

Can you talk after vocal cord cancer surgery?

Your ability to talk will depend on how much of your voice box was removed. If all of it was removed, you will need to learn new ways to communicate. If only a part of your voice box was removed, you may be able to talk after your throat has healed. Losing your ability to talk can be very upsetting and hard to accept.

How long does it take to recover from throat cancer treatment?

The course of treatment usually lasts for 3 to 7 weeks. As well as killing cancerous cells, radiotherapy can affect healthy tissue and has a number of side effects, including: sore skin which may look red or darker, depending on your skin tone (like sunburn)

Can you live a normal life after throat cancer?

With treatment, many people live a long life after throat cancer, especially when it's caught early.

Can larynx cancer be cured?

Generally, early laryngeal cancer has a better cure rate. Advanced cancer that spreads to other areas has a poorer survival rate. But even advanced laryngeal cancer can be cured. If it comes back, it usually happens within the first two or three years after treatment.

How long is hospital stay after throat surgery?

You are usually in hospital for around 11 days after surgery to remove your oesophagus. You'll need help when you first go home. The dietitian will talk to you and your family about what to eat. It can take some time to find what works for you.

Is vocal cord surgery painful?

You may experience minor discomfort in your throat or soreness in your jaw, but pain is rarely severe. Your doctor may recommend a dose of over-the-counter pain relief medication, if necessary.

How long is recovery after vocal cord surgery?

If your vocal cords were affected during the procedure, rest your voice completely for 3 days. If nodules or other lesions were removed from your vocal cords, you may have to follow total voice rest (no talking, whispering, or making any other voice sounds) for up to 2 weeks.

Can you fully recover from throat cancer?

Throat cancers may be cured when detected early. If the cancer has not spread (metastasized) to surrounding tissues or lymph nodes in the neck, about one half of patients can be cured. If the cancer has spread to the lymph nodes and parts of the body outside the head and neck, the cancer is not curable.

What is the success rate of radiation therapy for throat cancer?

Conclusion: In summary, radiotherapy is a suitable treatment modality for patients with early-stage laryngeal cancer, with an overall locoregional control rate of 84 per cent.

What are side effects of radiation for throat cancer?

Side effects of radiation therapy for laryngeal or hypopharyngeal cancerSkin problems in the area being treated, ranging from redness to blistering and peeling.Mouth sores.Dry mouth.Worsening of hoarseness.Trouble swallowing.Change of taste.Possible breathing trouble from swelling.Tiredness.More items...

How long does it take for laryngeal cancer to recur?

Patients treated for laryngeal cancers are at the highest risk of recurrence in the first 2 to 3 years. Recurrences after 5 years are rare and usually represent new primary malignancies. Close, regular follow-up is crucial to maximize the chance for salvage.

What are the prognostic factors for laryngeal cancer?

Prognostic Factors. The most important adverse prognostic factors for laryngeal cancers include increasing T stage and N (regional lymph node) stage. Other prognostic factors may include sex, age, performance status, and a variety of pathologic features of the tumor, including grade and depth of invasion.

What is the staging system for laryngeal cancer?

The staging system for laryngeal cancer is clinical and based on the best possible estimate of the extent of disease before treatment. The assessment of the primary tumor is based on inspection and palpation when possible and by fiberoptic laryngoscopy. Panendoscopy under anesthesia ensures careful clinical examination to determine clinical extent ...

What is laryngectomy?

Laryngectomy is reserved for patients with less than a 50% response to chemotherapy or who have persistent disease after radiation. [ 1 - 6] Definitive radiation therapy alone in patients who are not candidates for concurrent chemotherapy and surgery (total laryngectomy) for salvage of radiation failures.

Can you use fractionation alone for laryngeal cancer?

Radiation therapy alone with altered fractionation may be used for patients with locally advanced laryngeal cancer who are not candidates for chemotherapy. Altered fractionation radiation therapy yields a higher locoregional control rate compared with standard fractionated radiation therapy for patients with stage III and stage IV head and neck cancer.

Is radiation therapy a standard treatment for laryngeal cancer?

Surgery and radiation therapy have been the standards for treatment of laryngeal cancer; however, outcome data from randomized trials are limited. Studies have attempted to address the question of whether to use surgery or radiation, but the studies have been underpowered. [ 1] .

Can subglottic cancer cause throat pain?

Supraglottic cancers typically present with sore throat, painful swallowing, referred ear pain, change in voice quality, or enlarged neck nodes. Early vocal cord cancers are usually detected because of hoarseness. By the time they are detected, cancers arising in the subglottic area commonly involve the vocal cords; thus, symptoms usually relate to contiguous spread.

Who treats laryngeal cancer?

These doctors can include: An otolaryngologist (also known as an ear, nose, and throat, or ENT doctor): a surgeon who treats certain diseases of the head and neck. ...

What do people with cancer need?

People with cancer need support and information, no matter what stage of illness they may be in. Knowing all of your options and finding the resources you need will help you make informed decisions about your care.

What is the difference between a radiation oncologist and a medical oncologist?

A radiation oncologist: a doctor who treats cancer with radiation therapy. A medical oncologist: a doctor who treats cancer with medicines such as chemotherapy, targeted therapy, or immunotherapy. A plastic surgeon : a doctor who specializes in reconstructing or repairing parts of the body. An oral and maxillofacial surgeon : a dental surgeon who ...

What is the role of a dental surgeon in cancer?

An oral and maxillofacial surgeon : a dental surgeon who treats diseases of the mouth, teeth, and jaws. A speech therapist, an audiologist, and a dietician are also key players on your cancer care team.

What are the factors to consider when making a treatment plan for cancer?

In making your treatment plan, important factors to consider are the site and the stage (extent) of the cancer. Your cancer care team will also take into account your general health and your personal preferences. A major focus of treatment is to try to save your larynx and voice if possible. Most experts don’t recommend surgery ...

Why is communicating with your cancer team important?

Communicating with your cancer care team is important so you understand your diagnosis, what treatment is recommended, and ways to maintain or improve your quality of life. Different types of programs and support services may be helpful, and can be an important part of your care. These might include nursing or social work services, financial aid, ...

Why is it important to discuss all treatment options with your doctor?

It’s important to discuss all treatment options, including their goals and possible side effects, with your doctors to help make the decision that best fits your needs. For instance, if the cancer is too advanced to be cured, the goal may be to remove or destroy as much of the cancer as possible to keep the tumor from growing, spreading, ...

What to do after laryngectomy?

If you need more treatment after surgery, your options might include radiation therapy, chemoradiation, or surgery to remove more of the larynx. Supraglottic cancer: Supraglottic cancers are more likely to spread to the lymph nodes in the neck. If you're having surgery for supraglottic laryngectomy, the surgeon might also remove lymph nodes ...

What is the treatment for stage 1 hypopharyngeal cancer?

Stage I hypopharyngeal cancers. The main options for initial treatment of these cancers are surgery with or without radiation to the lymph nodes. Surgery includes removing all or part of the pharynx (throat) as well as lymph nodes on one or both sides of the neck (lymph node dissection).

What is the first treatment for cancer?

Another option is to first treat with both radiation and chemo ( chemoradiation ). If any cancer remains after treatment, surgery can try to remove it. A third option is to get chemotherapy as the first treatment, called induction chemotherapy.

What is the best treatment for thyroid cancer?

In these cases, the best treatment may be surgery to remove the larynx and nearby tissues with cancer (such as the thyroid gland). Another option may be to start with just chemotherapy, which is called induction chemotherapy. If the tumor shrinks, radiation therapy or chemoradiation is then given.

How to treat glottic cancer?

Glottic cancer: Some early glottic cancers might be treated by removing the vocal cord with cancer ( cordectomy ), or even by laser surgery. Radiation or surgery is usually enough to treat most glottic cancers unless there are signs that the treatment might not have cured the cancer (such as finding cancer cells at the edge of the removed tumor).

What to do if lymph nodes are enlarged?

If the tumor does not shrink, surgery might be done. If the lymph nodes in the neck are still enlarged after treatment, surgery can be done to remove them (lymph node dissection).

How to treat a cancerous neck?

One option to treat these cancers is surgery to remove the pharynx, larynx, thyroid gland, and lymph nodes in the neck. This is usually followed by radiation alone or radiation with chemo, especially if there's a high chance that the cancer will come back based on what is found during surgery.

How long does it take to cure larynx cancer?

Early cancers are remarkably curable with five-year survival or "cure rates" of 80-95% compared to advanced stages that have five-year survival rates of 25-50%.

How to cure advanced laryngeal cancer?

Standard treatment for patients with advanced laryngeal cancer has historically consisted of total laryngectomy , often combined with modified neck dissection. When metastatic cancer is present in the lymphatics of the neck, surgery is combined with radiation therapy . Five-year cure rates vary from 40-60%. The major sequelae of total laryngectomy include loss of natural voice and problems associated with living with a permanent tracheal stoma (hole in the neck). Modern voice restoration techniques with tracheoesophageal puncture (Blom-Singer prosthesis) has significantly reduced loss of voice as a result of total laryngectomy since the majority of patients are able to speak with a naturally sounding, lung powered voice and fewer patients must rely on the artificial electrolarynx or esophageal speech.

How to treat vocal cord cancer?

Early cancer of the glottis (vocal cords) or supraglottis (false vocal cords) can be effectively treated with either surgery alone or radiation therapy. Most surgical procedures can spare major portions of the voice box and with modern techniques, reconstruction of the voice box can be accomplished with preservation of reasonable voice quality and swallowing. The past ten years have seen the introduction of laser resections for many of these cancers thereby avoiding external neck incisions. In general, cancers that are superficial or limited in extent are best treated with laser removal. Similar tumors are also easily cured with 6-7 weeks of radiation treatment. Many physicians feel that voice quality may be better following radiation compared to surgery, but side effects of permanent dry mouth and risks of some long-term swallowing problems are associated with radiation. Decision making as to treatment of choice also depends on availability of skilled surgeons or radiation therapists and the depth of invasion (extent) and the overall size (volume) of cancer.

What are the causes of cancer in the larynx?

Tobacco use is known to be the major predisposing factor for laryngeal cancer. However, alcohol use, nutritional deficiencies, genetic predisposition and viral factors may also play a role. The vast majority (85-90%) of cancers of the larynx are squamous cell carcinomas that arise from the covering of the vocal cords.

What is the larynx?

Finally, the larynx is important in communication . The voice box consists of upper and lower components. The upper part is called the supraglottic larynx and consists of the epiglottis; false vocal cords and supporting muscles within the framework of the cartilaginous "box" called the thyroid cartilage.

What is the best way to diagnose neck cancer?

Radiologic imaging studies such as computerized tomographic (CAT) scans and magnetic resonance imaging (MRI) are often used to examine the neck for cancer spread outside the larynx or involvement of lymph nodes.

What kind of doctor is needed for cancer?

These cancers are usually slow growing and so, if necessary, there is ample time for consultation with both surgical, radiation and medical oncologists. Usually the surgical oncologist will "stage" the cancer and outline various treatment options and often will consult the specialists in the other disciplines.

What is the treatment for laryngeal cancer?

Treatment. Treating laryngeal cancer may involve multiple medical experts including otolaryngologists, surgeons, oncologists, and radiation oncologists. The exact method of treatment will depend on your particular situation but often will involve surgery to remove as much of the cancer as possible.

How do you know if you have laryngeal cancer?

Some possible symptoms are: hoarseness. sore throat. difficulty swallowing. difficulty breathing. bad breath. earaches.

What is the long term impact of laryngeal cancer?

Long-Term Impact. Depending on the stage of your cancer you may need a surgery called a partial laryngectomy or total laryngectomy, which involves a tracheostomy. Sometimes the tracheostomy is temporary but sometimes it is permanent. Perhaps one of the most devastating side effects of laryngeal cancer is its effects on speech.

What is it called when the cells in the larynx multiply?

When the cells that make up the tissue of the larynx begin to multiply and divide at an unusual rate it is called laryngeal cancer. The cells also grow abnormally large, usually forming a mass called a tumor. The tumor can displace and interfere with other organs surrounding the larynx and spread to other parts of the body.

What test is done to visualize vocal cords?

If necessary, other tests will be ordered and may include: Laryngoscopy - Indirect laryngoscopy can be preformed in your doctor's office. Your physician will put a mirror with a very long handle down your throat to visualize the vocal cords and surrounding tissues.

What is a laryngoscope?

The doctor will use a laryngoscope (a tube with a light on the end which is inserted through your nose or your mouth) to visualize the larynx. CT Scan. Biopsy.

Where is the larynx located?

Laryngeal cancer is cancer of the larynx (sometimes called the voice box), an organ located in the front of the esophagus between the pharynx and the trachea. The larynx assists in breathing, speaking, and even swallowing.

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Common Symptoms of Laryngeal Or Voice Box Cancer

How Cancer Affects Vocal Function

  • As tumors grow they encroach on the airway and affect the muscles of the voice box. These muscles are vitally important in providing protection of the trachea (windpipe) during swallowing of solids, liquids and saliva. When interfered with, closure of the larynx is incomplete and can lead to severe coughing, choking or even chronic pneumonia. The structure of the voice box also pro…
See more on rogelcancercenter.org

Cancer Evaluation and Staging

  • The first step in decision-making for patients with cancer of the larynx is accurate diagnosis and staging. This requires adequate tissue biopsy and histologic interpretation by a pathologist. Generally, these cancers are not difficult to diagnose by the pathologist, but if the clinical presentation is unusual (i.e. cancer in a younger person or non-smoker), or if the appearance is n…
See more on rogelcancercenter.org

Management Alternatives

  • Early Disease:
    Early cancer of the glottis (vocal cords) or supraglottis (false vocal cords) can be effectively treated with either surgery alone or radiation therapy. Most surgical procedures can spare major portions of the voice box and with modern techniques, reconstruction of the voice box can be ac…
  • Intermediate Disease:
    For those cancers that are of intermediate size (T2, small T3), treatment decisions are more difficult. Deeply invasive cancers are best treated with surgical excision, often combined with modified or selective neck dissection (removal of lymph nodes). Most of these procedures can …
See more on rogelcancercenter.org

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