FDA-Approved HIV Medicines
| Drug Class | Generic Name (Other names and acronyms) | Brand Name | FDA Approval Date |
| NRTIs block reverse transcriptase, an en ... | abacavir (abacavir sulfate, ABC) | Ziagen | December 17, 1998 |
| NRTIs block reverse transcriptase, an en ... | emtricitabine (FTC) | Emtriva | July 2, 2003 |
| NRTIs block reverse transcriptase, an en ... | lamivudine (3TC) | Epivir | November 17, 1995 |
- Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
- Nucleoside reverse transcriptase inhibitors (NRTIs)
- Protease inhibitors (PIs)
- Fusion inhibitors.
- CCR5 antagonists.
- Integrase strand transfer inhibitors (INSTIs)
- Post-attachment inhibitors.
What are the best medications for HIV?
“They will have to make their own decision, based on discussions with their provider, as to what is best for them,” he says. “Whatever option they choose, it is important for them to adhere to their medication as prescribed and have the periodic HIV ...
What are the different types of HIV medications?
The classes of anti- HIV drugs include:
- Non-nucleoside reverse transcriptase inhibitors (NNRTIs) turn off a protein needed by HIV to make copies of itself. Examples include efavirenz (Sustiva), rilpivirine (Edurant) and doravirine (Pifeltro).
- Nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs) are faulty versions of the building blocks that HIV needs to make copies of itself. ...
- Protease inhibitors (PIs) inactivate HIV protease, another protein that HIV needs to make copies of itself. Examples include atazanavir (Reyataz), darunavir (Prezista) and lopinavir/ritonavir (Kaletra).
What are the classes of HIV?
Viral infections typically induce very similar patterns of immune responses. These include an early induction of type 1 interferons secreted by dendritic cells, increased expression of interleukin-15, and a proliferation of natural killer (NK) cells.
What are the classes of medication?
a) pre anaesthetic medication • anti cholinergics • anti emetics • barbiturates • benzodiazepines • opoids . b) muscle relaxants • atracurium (tracrium) • succinylcholine (anectine) • vecuronium (norcuron) 2) general anaesthetics a) inhalant anaesthetics • enflurane (ethrane) • halothane (generic, fluothane)
What is HIV treatment?
HIV treatment (antiretroviral therapy or ART) involves taking medicine as prescribed by a health care provider. HIV treatment reduces the amount of...
When should I start HIV treatment?
Start HIV treatment as soon as possible after diagnosis. All people with HIV should take HIV treatment, no matter how long they’ve had HIV or how h...
What if I delay HIV treatment?
If you delay treatment, HIV will continue to harm your immune system. Delaying treatment will put you at higher risk for transmitting HIV to your p...
Are there different types of HIV treatment?
There are two types of HIV treatment: pills and shots. Pills are recommended for people who are just starting HIV treatment. There are many FDA-app...
What are HIV treatment shots?
HIV treatment shots are long-acting injections used to treat people with HIV. The shots are given by your health care provider and require routine...
Can I switch my HIV treatment from pills to shots?
Talk to your health care provider about changing your HIV treatment plan. Shots may be right for you if you are an adult with HIV who has an undete...
What are the benefits of taking my HIV treatment as prescribed?
HIV treatment reduces the amount of HIV in the blood (viral load). Taking your HIV medicine as prescribed will help keep your viral load low. HIV t...
Does HIV treatment cause side effects?
HIV treatment can cause side effects in some people. However, not everyone experiences side effects. The most common side effects are Nausea and vo...
What should I do if I’m thinking about having a baby?
Let your health care provider know if you or your partner is pregnant or thinking about getting pregnant. They will determine the right type of HIV...
Can I take birth control while on HIV treatment?
You can use any method of birth control to prevent pregnancy. However, some HIV treatment may make hormone-based birth control less effective. Talk...
What is the treatment for HIV?
HIV treatment involves taking medicines that slow the progression of the virus in your body. HIV is a type of virus called a retrovirus, and the combination of drugs used to treat it is called antiretroviral therapy (ART). ART is recommended for all people living with HIV, regardless of how long they’ve had the virus or how healthy they are.
Why do you prescribe HIV?
Your health care provider may prescribe medicines to prevent certain infections. HIV treatment is most likely to be successful when you know what to expect and are committed to taking your medicines exactly as prescribed.
What is drug resistance in HIV?
What Is HIV Drug Resistance? Drug resistance can be a cause of treatment failure for people living with HIV. As HIV multiplies in the body, it sometimes mutates (changes form) and produces variations of itself. Variations of HIV that develop while a person is taking ART can lead to drug-resistant strains of HIV.
How long do HIV side effects last?
Some side effects can occur once you start a medicine and may only last a few days or weeks.
How soon can you start ART for HIV?
Treatment guidelines from the U.S. Department of Health and Human Services recommend that a person living with HIV begin ART as soon as possible after diagnosis. Starting ART slows the progression of HIV and can keep you healthy for many years.
Is HIV treatment a prevention?
There is also a major prevention benefit. People living with HIV who take HIV medication daily as prescribed and get and keep an undetectable viral load have effectively no risk of sexually transmitting HIV to their HIV-negative partners. This is called treatment as prevention.
Can HIV be drug resistant?
A person can initially be infected with drug-resistant HIV or develop drug-resistant HIV after starting HIV medicines. Drug-resistant HIV also can spread from person to person. Drug-resistance testing identifies which, if any, HIV medicines won’t be effective against your specific strain of HIV.
What is the treatment for HIV called?
The treatment for HIV is called antiretroviral therapy (ART). ART involves taking a combination of HIV medicines (called an HIV treatment regimen) every day. ART is recommended for everyone who has HIV. People with HIV should start taking HIV medicines as soon as possible.
How many classes of HIV are there?
There are many HIV medicines available for HIV regimens. The HIV medicines are grouped into seven drug classes according to how they fight HIV. The choice of an HIV regimen depends on a person's individual needs.
How does HIV treatment affect the body?
By reducing the amount of HIV in the body, HIV medicines also reduce the risk of HIV transmission. A main goal of HIV treatment is to reduce a person’s viral load to an undetectable level. An undetectable viral load means that the level of HIV in the blood is too low to be detected by a viral load test.
Why is it important to have less HIV?
Having less HIV in the body gives the immune system a chance to recover and produce more CD4 cells.
How long after HIV infection can you start taking a drug?
(Early HIV infection is the period up to 6 months after infection with HIV.)
Can HIV be treated with ART?
People with HIV should start taking HIV medicines as soon as possible. ART can’t cure HIV, but HIV medicines help people with HIV live longer, healthier lives. ART also reduces the risk of HIV transmission. A main goal of HIV treatment is to reduce a person’s viral load to an undetectable level.
Can HIV medications interact with other HIV medications?
HIV medicines can interact with other HIV medicines in an HIV regimen or with other medicines a person is taking . Health care providers carefully consider potential drug interactions before recommending an HIV regimen.
Why is it important to take HIV medication?
Taking HIV medication consistently, as prescribed, helps prevent drug resistance. Drug resistance develops when people with HIV are inconsistent with taking their HIV medication as prescribed. The virus can change (mutate) and will no longer respond to certain HIV medication. If you develop drug resistance, it will limit your options ...
What is the amount of HIV in the blood called?
The amount of HIV in the blood is called viral load . Taking your HIV medicine as prescribed will help keep your viral load low and your CD4 cell count high. HIV medicine can make the viral load very low (called viral suppression ). Viral suppression is defined as having less than 200 copies of HIV per milliliter of blood.
What does it mean when your HIV is suppressed?
Viral suppression is defined as having less than 200 copies of HIV per milliliter of blood. HIV medicine can make the viral load so low that a test can’t detect it (called an undetectable viral load ). If your viral load goes down after starting HIV treatment, that means treatment is working.
How long does it take for a mother to give her baby HIV?
If a mother with HIV takes HIV medicine as prescribed throughout pregnancy, labor, and delivery and gives HIV medicine to her baby for 4 to 6 weeks after birth, the risk of transmitting HIV to her baby can be 1% or less.
How long does it take to get rid of HIV?
There is no effective cure for HIV. But with proper medical care, you can control HIV. Most people can get the virus under control within six months. Taking HIV medicine does not prevent transmission ...
What to do if substance use is interfering with your ability to keep yourself healthy?
If substance use is interfering with your ability to keep yourself healthy, it may be time to quit or better manage it. If you need help finding substance use disorder treatment or mental health services, use SAMHSA’s Treatment Locator. external icon. .
Does HIV harm the immune system?
HIV will continue to harm your immune system. This will put you at higher risk for developing AIDS. Learn more about AIDS and opportunistic infections. This will put you at higher risk for transmitting HIV to your sexual and injection partners.
What is the treatment for HIV?
However, there are many medications that can control HIV and prevent complications. These medications are called antiretroviral therapy (ART). Everyone diagnosed with HIV should be started on ART, regardless of their stage of infection or complications.
What are some examples of anti-HIV drugs?
Examples include efavirenz (Sustiva), rilpivirine (Edurant) and doravirine (Pifeltro).
What test can help determine if you have HIV?
If you receive a diagnosis of HIV / AIDS, several tests can help your doctor determine the stage of your disease and the best treatment, including: CD4 T cell count. CD4 T cells are white blood cells that are specifically targeted and destroyed by HIV. Even if you have no symptoms, HIV infection progresses to AIDS when your CD4 T cell count dips ...
What is HIV RNA?
Viral load (HIV RNA). This test measures the amount of virus in your blood. After starting HIV treatment the goal is to have an undetectable viral load. This significantly reduces your chances of opportunistic infection and other HIV -related complications.
How long does it take to get tested for HIV?
Most rapid HIV tests, including self-tests done at home, are antibody tests. Antibody tests can take three to 12 weeks after you're exposed to become positive. Nucleic acid tests (NATs). These tests look for the actual virus in your blood (viral load). They also involve blood drawn from a vein.
How to diagnose HIV?
Diagnosis. HIV can be diagnosed through blood or saliva testing. Available tests include: Antigen/antibody tests. These tests usually involve drawing blood from a vein. Antigens are substances on the HIV virus itself and are usually detectable — a positive test — in the blood within a few weeks after exposure to HIV.
What to do if you think you have HIV?
If you think you might have HIV infection, you're likely to start by seeing your family doctor. You may be referred to an infectious disease specialist — who additionally specializes in treating HIV / AIDS.
What are the two drugs that are used to treat HIV?
There are currently two FDA-approved PrEP agents, both of which are combinations of two HIV drugs in single pills: 1 Truvada — emtricitabine and tenofovir disoproxil fumarate 2 Descovy — tenofovir alafenamide and emtricitabine
How many types of medication are there for HIV?
A person with a recent HIV diagnosis usually starts treatment with a combination medication. There are at least 22 types, and a healthcare provider should recommend a combination medication that best suits a person’s requirements after a careful discussion of the options.
What is a non-nucleoside reverse transcriptase inhibitor?
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) prevent HIV from replicating by binding to and altering reverse transcriptase, which HIV use s to replicate. This reduces the viral load of HIV in the person’s body.
What is the CCR5 antagonist?
One of these receptors is the CCR5 coreceptor. CCR5 antagonists are drugs that block the CCR5 coreceptor, preventing HIV from attaching to and entering white blood cells.
How does antiretroviral therapy work?
In a person with HIV, antiretroviral therapy reduces the amount of the virus in the body to very low levels. When levels are so low that doctors consider them undetectable, the virus can no longer damage the body or transmit to others. recommend consistent treatment with antiretroviral therapy for everyone with HIV, ...
What is the treatment for HIV?
Side effects. Summary. Treatment for HIV involves taking medication that reduces the amount of the virus in the body. This is called antiretroviral therapy. Two other options, PEP and PrEP, can prevent HIV. HIV is a type of virus called a retrovirus. In a person with HIV, antiretroviral therapy reduces the amount of the virus in ...
How does HIV replicate?
Integrase inhibitors. After entering a white blood cell, HIV can replicate by inserting, or integrating, its DNA into that of the cell. This process relies on an enzyme called integrase. Integrase inhibitors disable the effects of the enzyme, thereby preventing HIV from inserting its DNA into the host cell.
What is the drug class for HIV?
By doing so, HIV can begin to churn out multiple copies of itself. Nucleoside reverse transcriptase inhibitors (NRTIs) block the action of reverse transcriptase and so prevent the replication of the virus. DRUG CLASS: Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Brand Name. Generic Name.
What enzyme is used to replicate HIV?
Nucleoside Reverse Transcriptase Inhibitors. In order for HIV to replicate, it uses an enzyme called reverse transcriptase to translate its viral RNA into double-stranded DNA, which is then integrated into the nucleus of the host cell to "hijack" its genetic machinery.
What antiretroviral drugs have been discontinued?
While several new antiretroviral drugs have been added to the treatment arsenal since 2010, older ones like Crixivan (indinavir), Invirase (saquinavir), Rescriptor (delavirdine), Videx (didanosine), Viracept (nelfinavir), and Zerit (stavudine) have been discontinued and are no longer in use. An Overview of HIV Treatment.
What is the purpose of antiretroviral drugs?
Latesha Elopre, MD, MSPH. on May 20, 2021. Ridofranz / Getty Images. Antiretroviral drugs are used to treat HIV infection. They work by blocking a stage of the virus's life cycle and, by doing so, prevent the virus from replicating.
What is the name of the drug that blocks reverse transcriptase?
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) also block reverse transcriptase but in a different way. Rather than attaching to viral DNA like NRTIs do, NNRTIs bind directly to the enzyme, blocking its action.
How many FDC drugs are there?
Some FDC drugs are used with other antiretroviral agents. Others are entirely used on their own. Of the 22 FDC drugs approved for use in the United States, 14 are all-in-one treatments taken once daily. Fixed-Dose Combination (FDC) Drugs. Brand Name.
What is a pharmacokinetic enhancer?
Pharmacokinetic Enhancers. Also called HIV boosters, these drugs are used to "boost" the concentration of protease inhibitors in the bloodstream. Without them, the concentration of the accompanying PI would quickly fall beneath the therapeutic level, providing the virus an opportunity to replicate.
Diagnosis
Treatment
- Currently, there's no cure for HIV/AIDS. Once you have the infection, your body can't get rid of it. However, there are many medications that can control HIV and prevent complications. These medications are called antiretroviral therapy (ART). Everyone diagnosed with HIV should be started on ART, regardless of their stage of infection or complicati...
Clinical Trials
- Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
Lifestyle and Home Remedies
- Along with receiving medical treatment, it's essential to take an active role in your own care. The following suggestions may help you stay healthy longer: 1. Eat healthy foods.Make sure you get enough nourishment. Fresh fruits and vegetables, whole grains, and lean protein help keep you strong, give you more energy and support your immune system. 2. Avoid raw meat, eggs and mo…
Alternative Medicine
- People who are infected with HIV sometimes try dietary supplements that claim to boost the immune system or counteract side effects of anti-HIVdrugs. However, there is no scientific evidence that any nutritional supplement improves immunity, and many may interfere with other medications you're taking. Always check with your doctor before taking any supplements or alter…
Coping and Support
- Receiving a diagnosis of any life-threatening illness is devastating. The emotional, social and financial consequences of HIV/AIDScan make coping with this illness especially difficult — not only for you but also for those closest to you. But today, there are many services and resources available to people with HIV. Most HIV/AIDSclinics have social workers, counselors or nurses wh…
Preparing For Your Appointment
- If you think you might have HIV infection, you're likely to start by seeing your family doctor. You may be referred to an infectious disease specialist — who additionally specializes in treating HIV/AIDS.