In short, radioiodine is administered as a salt pill or solution. Instead of being normal salt, sodium chloride (NaCl), it is sodium iodide (NaI). Once you swallow the treatment dose, iodine-131 (131 I) is rapidly absorbed into the circulation.
Full Answer
What is radioactive iodine therapy (RIT)?
Radioactive iodine therapy is a radiopharmaceutical. It involves the use of radioactive isotopes — in this case, Iodine-131 (I-131) — to diagnose or treat disease. How is radioactive iodine therapy used? Currently, radioactive iodine therapy is only used to treat hyperthyroidism (overactive thyroid gland) and certain types of thyroid cancer.
What should I do after radioactive iodine treatment?
After that, you should drink plenty of fluids to flush the radioactive iodine out of your system. You can eat as normal. The treatment makes you radioactive. So your sweat, urine and saliva will be radioactive for a few days.
How does radioactive iodine treat thyroid cancer?
Treatment with radioactive iodine helps reduce the risk that thyroid cancer will come back. It is also used to treat thyroid cancer that has spread. Radioactive iodine enters your bloodstream and is taken up by your thyroid cells. The radioactivity destroys the cancer cells.
What is a low-iodine diet for radioactive iodine therapy?
A low-iodine diet will make your radioactive iodine therapy more effective. If you have too much iodine in your diet, it can stop the thyroid cells from taking up the radioactive iodine. Continue to follow this diet for 24 hours after your treatment is completed, or as instructed by your doctor. Read the resource for more information.
Do you have to stay in the hospital after radioactive iodine treatment?
Having radioactive iodine treatment for thyroid cancer. Radioactive iodine treatment takes place in the hospital. You usually stay there for a few days until your radiation levels have fallen to a safe level. You will be looked after in a single room, where you stay alone.
How long do you stay in the hospital after radioactive iodine treatment?
Most people are in the hospital for 1 night. Your doctor will tell you if you need to stay longer. You'll have another whole-body scan several days after your treatment. This helps your doctor see where the dose of radioactive iodine was taken up in your body.
How do you prepare a patient for radioactive iodine therapy?
You might need to have a low iodine diet for a few weeks before you have your treatment. This prepares the thyroid cells so that they can absorb the radioactive iodine. All food and drink contains some iodine. A low iodine diet means that you should avoid foods that have a high level of iodine in them.
What care should be taken when a client is taking radioactive iodide?
Treatment procedure for radioiodine Rinse your washcloth and toothbrush well after use. Take care not to splash urine outside the pan when using the toilet and flush it twice after use (with the lid down). Men may find this easier if they sit down when passing urine. Use more toilet paper than you normally would.
Can you go home after radioactive iodine treatment?
After radioactive iodine treatment for thyroid cancer. Having radioactive iodine treatment means you will be radioactive for several days afterwards. You will be able to go home from hospital when the radiation level in your body is at a safe level.
Is it safe to be around someone after radioactive iodine treatment?
Keep Your Distance Here are some ways to minimize radiation risks to other people (and pets) after you have had RAI treatment: Stay at least six feet away from other people, including members of the public, family members, and co-workers, for three to 11 days.
When can I eat regular food after radioactive iodine?
Drink only water. For 3 days after you swallow the capsule: Follow your low-iodine diet. You may resume your normal diet after 3 days. For 1 or 2 days after your dose: Avoid fatty or rich foods to help ease any nausea.
What can I expect from radioactive iodine treatment?
Short-term side effects of RAI treatment may include: Neck tenderness and swelling. Nausea and vomiting. Swelling and tenderness of the salivary glands.
Do you have to isolate after radiation?
You are also required to self isolate for 7 days after your radioiodine treatment in order to minimise the risk of contracting COVID-19 whilst there is still a large amount of radioactivity in your body. A small proportion of people with COVID-19 may become very unwell and require admission to hospital.
How to reduce radioiodine contamination?
Since most of the radioiodine leaves your body in your urine, good toilet hygiene and careful, thorough washing of your hands will reduce the possibility of contamination.
How to avoid radiation exposure?
There are three basic principles to remember: 1 Distance: The greater the distance you are from others, the less radiation they will receive. Try not to remain in close contact with others for longer than is necessary. 2 Time: Radiation exposure to others depends on how long you remain close to them. You should try to minimize the time spent in close contact with others. 3 Hygiene: good hygiene minimizes the possibility that other people will be contaminated with the radioiodine that leaves your body. Since most of the radioiodine leaves your body in your urine, good toilet hygiene and careful, thorough washing of your hands will reduce the possibility of contamination.
How often do radiation safety specialists come to your room?
A radiation safety specialist will come to your room one to two times a day to measure your radiation levels. These radiation levels will be less everyday. On discharge from the hospital, a minimal amount of radiation remains in your body and will go away over the next several weeks.
How far away should family members be from you on radiation?
If you are treated as an outpatient, family members should not come closer than six feet from you the first day and three feet the second day. Further precautions will most likely not be necessary after this, but this will be determined by the radiation safety specialists with a specific measurement.
What to wear to stay in a hospital?
Plan to wear a hospital gown and slippers as you will be confined to your room. Do not bring a suitcase full of personal items. Anything that is taken into your room will need to be checked by the radiation safety office before it can be removed. This is to keep the radioactive material from going into public areas.
Can you return home after iodine?
Most patients, however, are able to return home immediately after administration of the iodine, and will need to follow specific radiation safety precautions at home. If you are admitted to the hospital, your room will have a protective covering on the floor.
Is iodine 131 radioactive?
Iodine-131 (I-131) is radioactive. Radiation can be measured around your body and I-131 is present in your skin oil and sweat. Whatever touches your skin will pick up a small amount of radiation. The I-131 leaves your body through your urine primarily. Small amounts of I-131 may also leave through your saliva, sweat and feces.
How long before I-131 injections?
You may receive injections of a medication called Thyrogen over two days prior to your I-131 therapy. Thyrogen is recombinant TSH and these injections will elevate the TSH level in your blood, which in turn stimulates the thyroid cells to take up the I-131.
What is radioactive iodine?
Radioactive iodine (I-131) Therapy for Thyroid Cancer. Radioactive iodine (RAI) is a therapy used in the treatment of some thyroid cancers, specifically papillary and follicular thyroid cancer. For the thyroid gland to make thyroid hormone, the first step in the process is for the thyroid cells to "take up" iodide from the bloodstream.
What is the first step in thyroid hormone production?
TSH is what signals the thyroid cells to produce thyroid hormone and, as discussed above, the first step in thyroid hormone production is for the thyroid cells to take up iodide from the bloodstream. Therefore, to maximize the amount of I-131 that enters the thyroid cells, your TSH level must be high.
What is RAI for thyroid cancer?
RAI for remnant ablation destroys any residual normal thyroid tissue, allowing your physicians to more easily detect if your thyroid cancer comes back . A blood test called thyroglobulin is used in surveillance monitoring of thyroid cancer.
What is RAI used for?
This therapy can be used for several purposes: The most common use of RAI is to destroy (called "ablate") the small amount of normal thyroid that remains (called the "remnant") after you have had thyroid surgery (near-total or total thyroidectomy). This use of RAI is called remnant ablation. Sometimes, but not always, thyroid cancer cells are also ...
How long after I-131 treatment can I go home?
After the whole body scan is completed, you will then receive the oral I-131 treatment pill. After taking the I-131, you will be sent home or, rarely, you may be required to remain in the hospital for a few days . You will be asked to return to the nuclear medicine department 7-10 days later to have another whole body scan, also known as the "post-therapy scan," that will show where the I-131 was deposited in your body. This scan may also identify any new sites of iodine-avid thyroid cancer not seen on the first whole body scan.
How long does it take for I-131 to work?
To prepare you for I-131 therapy and to maximize the effects I-131, there are two things that must happen. First, you must follow a low iodine diet for 1-2 weeks to deplete your body of iodine. Iodine is found in many foods that we eat. This will make your thyroid cells "hungry" for the I-131 and help to increase the amount ...
How long does it take for thyroid to stop taking up radioactive iodine?
If you have too much iodine in your diet, it can stop the thyroid cells from taking up the radioactive iodine. Continue to follow this diet for 24 hours after your treatment is completed, or as instructed by your doctor. Read the resource for more information.
How long after radioactive iodine therapy can you get pregnant?
Pregnancy and radioactive iodine therapy. Don’t get pregnant or get your partner pregnant for at least 6 months after getting radioactive iodine therapy, or as long as your doctor tells you to. Use birth control after treatment for at least 6 months after getting this treatment.
What is the name of the service that takes up thyroid cells?
If you do, tell your doctor in Molecular Imaging and Therapy Service (MITS) before your treatment. This is sometimes called the Nuclear Medicine service. Radioactive iodine enters your bloodstream and is taken up by any thyroid- like cells. The radioactivity destroys the cancer cells.
How to treat thyrotropin alfa?
Your treatment plan will follow these steps that will take place over a few days: 1. On the first day, you’ll have blood tests. After those tests, you’ll see your doctor and get a thyrotropin alfa (Thyrogen ®) injection (shot) to help you get ready for your treatment.
Where does radioactive iodine leave the body?
Most of the extra radioactive iodine will leave your body through your urine (pee), and smaller amounts will leave your body in your saliva (spit), sweat, and bowel movements (poop).
How long before breast cancer treatment can you pump milk?
To prevent having radioactive iodine collect in your breast after your treatment, you’ll need to stop breastfeeding or pumping breast milk at least 6 to 12 weeks before your treatment.
Why does my mouth dry out after iodine?
Dry mouth. This is also caused by irritation or damage to your salivary glands. Dry mouth may happen if you’re taking a higher dose of radioactive iodine. Dry mouth can happen right after treatment, or it may happen for several months to a year after treatment.
What is radioiodine used for?
What is radioiodine? Radioiodine (sodium I-131) is a form of radiation therapy that has been used for many years to treat thyroid conditions. It is safe and effective but requires you to observe certain precautions to decrease the small amount of radiation that other people may receive from your body and bodily fluids.
How can radiation exposure be reduced?
Radiation exposure to other people can be reduced by keeping a reasonable distance between yourself and others and keeping the time you are close to others to a minimum. Your doctor should review the following instructions with you and answer all of your questions.
How long should you wait to breastfeed after radioiodine?
You must stop breastfeeding before you can be treated with radioiodine. If possible, you should stop breastfeeding for 6 weeks prior to treatment. You should not resume breastfeeding after treatment for your current child, but you may safely breastfeed babies you may have in the future.
How long does radioiodine stay in your system?
Radioiodine stays in your body for only a short time. Most of the radioiodine that does not go to thyroid tissue will be eliminated from your body during the first few days after treatment. Radioiodine leaves your body primarily through your urine, but very small amounts can be found in your saliva, sweat and bowel movements.
How long does radioactive iodine treatment last?
Having radioactive iodine treatment for thyroid cancer. Radioactive iodine treatment takes place in the hospital. You usually stay there for a few days until your radiation levels have fallen to a safe level. You will be looked after in a single room, where you stay alone.
How long after iodine treatment can you drink?
The capsule is about the size of a paracetamol capsule. You won’t be able to eat or drink for a couple of hours afterwards so that your body can absorb the iodine. After that, you should drink plenty of fluids to flush the radioactive iodine out of your system.
How long does saliva stay radioactive?
So your sweat, urine and saliva will be radioactive for a few days. There are certain precautions that you and the staff need to follow. Try not to be alarmed by these. Your treatment contains a low dose of radiation that is necessary to treat your cancer.
How Do I Prepare For The Treatment?
- If you’re a woman of childbearing age (13 to 50), you will need to have a pregnancy test before you receive radioactive iodine. Your referring doctor will order this test.
What Will Happen During The Treatment?
- The doctor treating you will explain the procedure and the expected outcome of this therapy with you. We will ask you to sign a consent form. We will provide the treatment in the form of one capsule for you to swallow.
What Will Happen After The Procedure?
- You will need to take steps to minimize radiation exposure to your family and the general public. The radioiodine will only be in your body in insignificant amounts for the first 48 hours. Use the following guidelines to avoid unnecessary exposure to individuals around you: 1. If you are a woman, you should protect against pregnancy for six months after treatment. 2. Maintain a reas…
Remnant Ablation
- RAI for remnant ablation destroys any residual normal thyroid tissue, allowing your physicians to more easily detect if your thyroid cancer comes back. A blood test called thyroglobulin is used in surveillance monitoring of thyroid cancer. Thyroglobulin is a protein that is only produced by either normal thyroid cells or thyroid cancer cells. After surgery you may still have a small amount of n…
Rai Effect on Cancer Cells
- Some thyroid cancer cells also share the same ability as normal thyroid cells to take up iodine from the bloodstream. These are referred to as "iodine-avid". If your cancer cells are able to do this, then I-131 may also destroy microscopic residual thyroid cancer cells or be used as a treatment for thyroid cancer that has spread to lymph nodes or other areas of the body. Doctors …
Preparing For Treatment
- Although I-131 is a pill, you cannot simply take the pill without prior preparation. To prepare you for I-131 therapy and to maximize the effects I-131, there are two things that must happen. First, you must follow a low iodine diet for 1-2 weeks to deplete your body of iodine. Iodine is found in many foods that we eat. This will make your thyroid ...
Treatment Procedure
- Prior to treatment, patients will have a "whole body scan" that is performed one day after taking a small dose of a different radioiodine isotope (I-123). I-123 does not destroy thyroid cells and will allow your treatment team to visualize the location and amount of any remaining thyroid remnant and possibly thyroid cancer. After the whole body scan is completed, you will then receive the or…
Safety After Treatment
- I-131 remains in your system for up to a few weeks and excess not taken up by the thyroid is excreted in urine, stool, saliva and perspiration over the first 1-2 days following treatment. As the radioactivity of the I-131 in your system is a concern for those around you, you need to follow radiation safety precautions after receiving I-131. The length of time one has to follow these pre…
Resources For More Information
- ThyCa: Thyroid Cancer Survivors' Association, Inc. National Cancer Institute Thyroid Cancer Page American Thyroid Association Radioactive Iodine FAQ's