
Other side effects that have been reported include:
- Liver failure
- Kidney failure
- Dry eye
- Clotting disorders
- Internal hemorrhage
- Skin disease and itching
- Vomiting
- Diarrhea
- Inappetence
- Drooling
Are there any side effects to oral flea treatment for dogs?
Side Effects Of Oral Flea And Tick Meds But dog owners have reported some pretty serious side effects. They’re often neurological in nature, like seizures. That’s because most of these products kill the pests by attacking the nervous system and paralyzing them.
What are the most common side effects of flea medications?
The most common side effect reported for prescription oral flea medications is vomiting. No medication is without the risk of side effects, but leaving parasites untreated is far more dangerous.
Can Oral Flea and tick medications cause vomiting?
Oral flea and tick medications are great for households with small children or other small pets who may be in danger of coming into contact with the chemical residue from flea collars or topical medications. The most common side effect reported for prescription oral flea medications is vomiting. No...
What are the side effects of permetherin in flea treatment?
Permetherin is an example of this and can be found in some spot treatment products. It can cause itching where the medicine was placed, weakness, vomiting, and a change in a dog’s behavior such as hyperactivity or depression. Resistance to flea products is also not uncommon.

Can oral flea medicine make a dog sick?
When used as directed, such products are safe and effective. However, dogs and cats can easily become sick if too much or the wrong flea product is applied, or the product is ingested post-application. Ingestion occurs if the dog or cat licks the treated area.
Why does my dog act weird after flea treatment?
The ingredients in a flea medicine can be an allergen to certain dogs and behaving weird could be due to an allergic reaction. Wounds: if the dog has a wound on their skin near where the pipette has been administered, it is possible the toxicity can cause a reaction.
Are oral flea treatments better than topical?
The ninety-day study found that topicals were 88.4 percent effective, while oral treatments were 99.9 percent effective.
How long do side effects from flea medicine last?
Human descriptions of pyrethroid paresthesia vary from “tingling” to “pins and needles” to “burning” sensations in the skin at the site of pyrethroid contact. These sensations begin within 30 minutes of application and may last 8 to 24 hours if untreated.
Does dog flea treatment have side effects?
Mild Reactions Itching at the spot the medication was applied. Respiratory issues. Paw flicking, ear twitching, vomiting and diarrhea.
How can I tell if my dog is allergic to flea medicine?
Allergic reactions -- hives, congestion, itching, extreme sensitivity, shock, respiratory distress, death (very rare) Idiosyncratic reactions -- resembles toxic reactions at much lower doses. Mild reaction -- excessive (hyper) salivation, paw flicking, ear twitching, mild depression, vomiting, diarrhea.
Is oral flea treatment safe?
#1 Definitely Not Safe – Oral Flea And Tick Preventatives. These are the worst offenders and most dangerous to use on your dog. They're taken orally, usually as a tasty chew for your dog. These drugs contain isoxazolines.
How long does it take for oral flea medicine to work?
After ingestion, some oral flea, like Trifexis, preventatives begin to kill fleas in at little as 30 minutes and kill 100% of fleas within 24 hours. Fluralaner, afoxolaner, spinosad, milbemycin oxime, praziquantel, and sarolaner are among the many common ingredients found in oral flea and tick preventatives.
What is better flea collar or pill?
Collars are a good choice for those who don't want to be on a monthly schedule of applying a topical between the shoulder blades or giving tablets by mouth, which some dogs hate. They last up to 6 to 8 months at a time.
Does flea medicine have side effects?
Although most dogs and cats handle this powerful pesticide just fine, others can have severe reactions, the U.S. Food and Drug Administration said Thursday. Isoxazoline products have been associated with neurologic reactions, including muscle tremors, loss of muscle control and seizures.
Why is my cat acting weird after flea treatment?
If your flea already has a flea infestation, then they might be acting irritable or annoyed because of the fleas. It might take a little time for the treatment to become effective. Another reason your cat might be acting weird is that you have had to take them to the veterinarian.
Can flea treatment make my dog drowsy?
However, both dogs and cats can have serious adverse reactions to some of these ingredients, even when the product is used according to label directions. Side effects can include skin irritation, agitation or lethargy, vomiting, tremors and seizures.
What is oral flea and tick medicine?
What It Is. Oral flea and tick medications are pills or tablets that treat and prevent infestations.
Can flea pills cause vomiting in dogs?
Precautions: Are Flea Pills Safe for Dogs and Cats? May cause vomiting in some pets. Less commonly seen side effects are lethargy, itching, excessive salivation, or rarely, seizures. Make sure to give the dose appropriate for your pet’s weight and species.
Does Sentinel kill fleas?
Note: Sentinel contains an ingredient to stop the development of flea larvae but does not kill adult fleas. Fleas and ticks: Bravecto (every 12 weeks), Nexgard, (for monthly use). Image: Ermolaev Alexander / via Shutterstock.
How to report a problem with a veterinary product?
To report a problem or to get more information about the product you use, contact the following companies directly: If you or your veterinarian have additional questions, contact the FDA at [email protected], or call 240-402-7002.
What is the FDA approved drug for dogs?
The FDA-approved drugs in this class are: Bravecto. Credelio. Nexgard. Simparica. Although these products can be safely used for most cats and dogs, the FDA advised that you check with your veterinarian to review your pet's medical history to be sure these products are safe for your pet.
Can flea medicine affect pets?
FDA: Pets May Have Bad Reactions to Flea Medicine. FRIDAY, Sept. 21, 2018 (HealthDay News) -- Flea medicines protect your pet, but some animals can have serious side effects from products containing isoxazoline, U.S. health officials warn. Although most dogs and cats handle this powerful pesticide just fine, others can have severe reactions, ...
Can dogs have seizures from isoxazoline?
Isoxazoline products have been associated with neurologic reactions, including muscle tremors, loss of muscle control and seizures. Most dogs and cats don't have bad reactions to these products, but seizures can occur even if they haven't happened before, the agency said. The FDA-approved drugs in this class are: Bravecto. Credelio.
What are the best treatments for fleas and ticks?
Types of Medicines for Fleas and Ticks. There are shampoos, topicals, insecticides and flea and tick collars that can prevent the attachment of any tick to the skin of an animal.
How long does it take for a tick collar to work?
Some collars and topicals work for 1 to 2 months and can easily be applied. It is important to prevent a tick from attaching itself to any animal for a 48-hour period. After being attached for 48 hours, a tick will secrete fluids that can sicken the animal.
Can flea and tick medicine be used on cats?
Flea and tick medicine can be used to prevent infestations of either or both fleas or ticks or can be used to eradicate either or both after an infestation has occurred. Unfortunately, use of such medicines can produce side effects in both dogs and cats. Sometimes the symptoms can be mild and short term and therefore acceptable considering ...
Can permethrin be used on dogs?
For example, permethrin should not be used on dogs that interact with cats or that play in water, such as ponds, etc. since the substance is extremely toxic to aquatic life within the first 48 hours after application of the product. Do not use in conjunction with other flea or tick control products such as flea collars.
Can you use flea collars on pregnant animals?
Do not use in conjunction with other flea or tick control products such as flea collars. Before using on pregnant or nursing animals, check with a veterinarian. Before using on an animal with heart, liver or kidney disease or any other serious ailment, check with a veterinarian.
Can you use flea medicine on a dog?
Precautions When Using Flea or Tick Medications. Some medicines should not be used on cats but can be used safely on dogs and visa versa. The medication Permethrin is an example of one such drug that should not be used on cats or even on dogs that interact with cats.
What is the best flea control for dogs?
There are a variety of options a pet owner can choose when it comes to dog flea control: monthly topical “spot” solutions, sprays, shampoos, and pills or tablets. If a veterinary clinic does not administer the dog flea control product, and one purchases an item over-the-counter, dosing instructions should be strictly followed.
Why is my dog not getting flea control?
The reason for this is usually not because of the quality of the product—it’s because of misapplication on the part of the person administering the product. If a pet owner is not sure about what flea products is best for a dog, a veterinarian should be consulted so the proper flea control product can be purchased and administration instructions ...
How many people died from fleas in 2008?
In 2008, over 1,000 deaths and over 40,000 severe reactions were reported as a result of flea control products in pets.
Does flea shampoo kill fleas?
Flea shampoos for dogs, for example, contain toxins, insecticides, and neurotoxins to kill fleas . The dog’s immune system can weaken over time because of the toxins found in the shampoo. At the same time, fleas can build up more resistances against the ingredients in the flea shampoos with every new generation.
Can flea control products cause side effects?
Common Side Effects of Dog Flea Control Products. Many flea control product manufacturers state their products have a little to no side effects, but there are ingredients within them that have proven to be hazardous to a dog’s health. Side effects to a dog flea control product include irritation or redness where a topical product was placed, ...
Is flea control safe for dogs?
While veterinarian state flea control products for dogs are safe (even over-the-counter products), the EPA is studying these flea control aids for safety and efficacy.
Can flea medicine cause itching?
Certain ingredients in flea control products have been known to cause more side effects than others. Permetherin is an example of this and can be found in some spot treatment products. It can cause itching where the medicine was placed, weakness, vomiting, and a change in a dog’s behavior such as hyperactivity or depression.
What are the chemicals used to treat fleas?
They’re potent and dangerous enough. They include acaricides that are pesticides poisonous to ticks and mites. Ectoparasiticides are to treat external parasites like fleas, ticks, lice, mites and flies.
What is the best flea control?
Lotilaner – an ectoparasiticide belonging to the isoxazoline family, with a 1 month duration. Spinosad – made from soil bacteria that is toxic to insects and found in garden insect spray. Lufenuron – controls flea infestations by preventing the hatching of eggs, and prevents the flea shell from developing.
How do flea and tick preventatives work?
How Oral Flea And Tick Preventatives Work. When you give your dog isoxazolines, they work systemically. This means they’re absorbed into his blood and they affect the entire body. When fleas and ticks feast on your dog’s blood, they eat the chemicals … and become paralyzed and die.
How long does flea and tick prevention last?
Here’s a reminder of some things to beware of. Duration of prevention. Avoid the longer-lasting 8 to 12 week products. Longer prevention means a more potent product and longer time in your dog’s system.
How long do tick collars last?
The second riskiest category is impregnated flea and tick collars that your dog wears all day and all night for as long as 8 months. So they’re right under your dog’s nose all the time. The absorption of chemicals is through the skin. And unlike oral flea and tick preventives, your dog isn’t supposed to eat these.
How long does it take for a dog to die from fleas?
When a flea or tick draws blood from your dog it’s infected with the chemical and dies. This takes place over several months while your dog wears the collar.
What is the name of the drug that binds to chloride channels inside a flea?
These drugs contain isoxazolines. And they’re usually only available by prescription. Many of these meds contain a class of ingredients called isoxazolines. They’re non-competitive GABA (gamma-aminobutyric acid) receptor antagonists. This means they bind to chloride channels inside the flea or tick.
What is the best flea treatment for dogs?
Types of Safe Flea Treatments for Dogs. Veterinarians typically recommend dog flea and tick collars, topical flea and tick treatments , or oral flea and tick medications (sometimes in combination) to fully protect their patients. Here are a few of the safest flea treatments for dogs on the market today and some of their pros and cons.
How to treat fleas and ticks in dogs?
Keep in mind that no two pets are the same. Therefore, a product that’s commonly considered to be safe flea and tick prevention for dogs may be a great option for one animal and a mistake for another. Factors to consider include: 1 Age: Flea treatments must be age-appropriate; many are not made for young puppies. Look at the product’s label for this information. 2 Breed: Coat type may influence your decision. Thicker coats may be difficult for topical treatments. 3 Your pet’s health history: Other medications or supplements that you give, concurrent health conditions, and previous reactions to flea and tick preventatives should be taken into account. For example, neurologic problems have been seen in dogs when high doses of ivermectin (heartworm prevention ingredient) are given in conjunction with spinosad, a flea preventative ingredient. 4 Your pet’s lifestyle: The presence of children and other pets (especially cats) in the household and your pet’s daily activities/exposure to the outdoors are important details. 5 Where you live: Which parasites are common in your area? Is resistance to certain preventatives a concern?
What factors to consider when treating a puppy for fleas?
Factors to consider include: Age: Flea treatments must be age-appropriate; many are not made for young puppies. Look at the product’s label for this information. Breed: Coat type may influence your decision. Thicker coats may be difficult for topical treatments. Your pet’s health history: Other medications or supplements that you give, ...
Can flea and tick collars be used on cats?
As is the case with flea and tick collars, if you’re unable to keep your pet away from small children or animals who may come into direct contact with the medication before it has dried or absorbed into your pet’s skin, a topical treatment might not be the ideal solution. If you have cats in your home, you will want to talk to a veterinarian ...
Is a flea collar safe for dogs?
Under many circumstances, newer dog flea collars are safe options for flea and tick control (unlike older collars, which were largely ineffective). The Seresto collar is a very popular option right now. It uses flumethrin and imidacloprid to kill fleas at multiple stages of development as well as ticks. The collar’s effectiveness lasts ...
Does Frontline Plus work?
Frontline Plus is an OTC product that uses fipronil and (S)-methoprene to attack fleas and ticks at every life stage. It also eliminates chewing lice and helps to control sarcoptic mange infestations. While it shouldn’t be ingested, a few surreptitious licks by your dog won’t cause much in the way of problems.
Can you treat a dog with thick coats?
Thicker coats may be difficult for topical treatments. Your pet’s health history: Other medications or supplements that you give, concurrent health conditions, and previous reactions to flea and tick preventatives should be taken into account.
What is the best treatment for fleas?
Flea pills are just one option for flea treatment and prevention. Topical applications, flea collars, flea shampoos, and environmental insecticides are also options to help you deal with a flea infestation.
How long does flea medicine stay in dogs system?
If you are looking for an oral monthly preventative, then a fast-acting flea pill that only stays in your dog’s system for a few days is probably not your best bet. On the other hand, if your dog is suffering from flea allergy dermatitis, then a fast-acting flea adulticide is exactly what you need.
Can I order flea pills for dogs?
Your veterinarian is your best source for discovering which flea pill will be most effective against a resistant flea population. It is possible to order some flea pills for dogs online or from a pet store without a veterinarian, but many of these pills do require a prescription.
Can flea pills be used on dogs?
You’ve probably heard someone in your life mention flea pills for dogs. These pills can be a very effective method for getting rid of fleas on dogs, and there are more options available today than ever before. Here is what you need to know about flea pills to help you choose the best option for your dog.
Can a dog have fleas while pregnant?
Pre-existing medical conditions, your dog’s age, and whether or not she is pregnant can also help determine the right flea product for your dog. In some cases, a fast-acting flea pill that kills fleas within a few hours can be part of a treatment plan for flea allergy dermatitis.
Can fleas be on dogs?
parasites. The flea circus your grandfather told you about was cute. Fleas on your dog are not . If your home feels like it is turning into your very own flea circus, you definitely need to take some action. You’ve probably heard someone in your life mention flea pills for dogs. These pills can be a very effective method for getting rid ...
Do you have to treat your home for fleas?
In most cases of flea infestations, you will also have to treat your home and yard for fleas, along with any other pets in the household, and you will need to stay on top of your flea and tick preventative schedule in order for it to remain effective.
What are the side effects of flea spray?
They include “spot-on” products applied to an animal’s skin, flea sprays, powders and collars. Many can cause nausea, vomiting and neurological side effects.
Why do people use flea products?
There are good reasons to use flea products. Fleas and ticks carry a range of diseases, including plague and Lyme disease, which can affect animals and their owners. Pets can develop allergies or sensitivities to the bites, and lose large patches of fur as a result.
What is the name of the flea pill?
The flea pills and chews all contain a pesticide called isoxazoline, the FDA said. They include products sold under the brand names Bravecto, Nexgard and Simparica. “Another product in this class, Credelio, recently received FDA approval.
Is isoxazoline safe for dogs?
These products are approved for the treatment and prevention of flea infestations, and the treatment and control of tick infestations,” the FDA said in a statement. “Isoxazoline products have been associated with neurologic adverse reactions, including muscle tremors, ataxia and seizures in some dogs and cats,” the FDA added.
Is Permethrin safe for dogs?
Products containing permethrin are safe for dogs but can be toxic to cats. “If you have both dogs and cats in your household, you should be aware that using a permethrin ‘spot-on’ product on a dog may cause illness in a household cat,” the FDA noted.
Do chews have neurological effects?
The label s on the products, sold mostly as flavored chews, already mention the risk of neurological side effects, and the risks have been reported by consumer groups. It is just important for vets and owners to get more information, the FDA said.
Can fleas be given to cats?
“Flea treatments meant for dogs can be deadly if given to cats instead. It is important to use only flea and tick products specifically designed for cats, and to administer the proper dosage,” the FDA cautions.

What Side Effects Are Possible When Using These Drugs?
- Neurological side effects or adverse reactions can range from barely noticeable to severe. Adverse reactions to these compounds appear to affect animals randomly, although those with certain chronic diseases, the young and elderly, and animals that are immune-compromised or have the genetic mutation of the MDR1 gene seem to be at higher risk. A sur...
What Should I Do If I Believe My Pet Is Having An Adverse reaction?
- Milk Thistle 50-100mg per 25lbs twice daily (you can also use Hepato Supportor Liver Tonic)
- NAC500mg twice daily for 2 weeks then once daily for two weeks
- Chlorella 25mg twice daily for 3 weeks
- The Chinese Herb Di Tan Tang for seizures 0.5 gm per 20 pounds body weight twice daily until the pet has been free of seizures for at least three months
Report The Incident to The FDA and The Manufacturer!
- To report suspected adverse drug events for these products and/or obtain a copy of the Safety Data Sheet (SDS) or for technical assistance, contact the appropriate manufacturers at the following ph...
- If you prefer to report directly to the FDA, or want additional information about adverse drug experience reporting for animal drugs, see How to Report Animal Drug and Device Side Effect…
- To report suspected adverse drug events for these products and/or obtain a copy of the Safety Data Sheet (SDS) or for technical assistance, contact the appropriate manufacturers at the following ph...
- If you prefer to report directly to the FDA, or want additional information about adverse drug experience reporting for animal drugs, see How to Report Animal Drug and Device Side Effects and Produ...
- Pet owners and veterinarians who have additional questions can contact [email protected] call 240-402-7002.
What Are The Long Term Effects?
- With the cases I have seen so far, some animals are able to make a full recovery while others will experience side effects forever. Using my protocol, I have been able to help improve the quality of life of many animals, but it is important to remember that the damage done may be permanent. Some of my clients now have to deal with seizures or other neurological side effects for the rest …