Treatment FAQ

what percent of cancer patients experience a major depressive episode during treatment

by Uriah Hodkiewicz Published 3 years ago Updated 2 years ago

A systematic review and meta-analysis shows the prevalence of major depression (15%), minor depression (20%), and anxiety (10%) in patients treated for cancer. 4 These figures greatly exceed population estimates of past-year depression (5%) and anxiety (7%). 8 Two thirds of patients with cancer and depression also have clinically significant anxiety symptoms. 3 Figures vary by cancer type, with major depression affecting an estimated 13% of patients with lung cancer, 11% of those with gynaecological cancers, 9% in breast cancer, 7% in colorectal cancer, and 6% in genitourinary cancers. 9 The highest levels of anxiety are reported in lung, gynaecological, and haematological cancers. 10 Evidence suggests these variations relate to the differing prognoses, pain levels, and degrees of body image disruption associated with each tumour type, as well as specific tumour-related neuropsychiatric effects and treatment-related neuropsychiatric side effects. 3

Overview. Depression is a comorbid disabling syndrome that affects approximately 15% to 25% of cancer patients. [1-3] Depression is believed to affect men and women with cancer equally, and gender-related differences in prevalence and severity have not been adequately evaluated.6 days ago

Full Answer

How common is depression in cancer patients?

Jul 23, 2018 · With one in three people experiencing a major depressive episode in their lifetime, clinical depression is more common than many people realize. And a major life event like a cancer diagnosis and cancer treatment – whether your own or that of a loved one – can trigger it. In fact, as many as 25% of cancer patients are dealing with depression.

What are the risk factors for depressive symptoms in cancer survivors?

Jun 10, 2019 · Anywhere from 10 to 60 percent experience some degree of depression, and approximately 20 percent meet criteria to be said to have experienced a major depressive episode. “People with prior history of depression are much more prone to experience depression during cancer treatment,” Dr. Johnson says.

What percentage of patients with major depressive disorder respond to drug treatment?

Mar 04, 2022 · In a study conducted in 1988 with a sample of 30 adolescent cancer patients, the rate of major depression was not higher than the rate for the population at large.[Level of evidence: II] One review reported a 17% incidence of depression using the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition.

Is it normal to feel depressed during cancer treatment?

Feb 09, 2015 · Depression is a common comorbidity in cancer cases, affecting >10% of patients. A cancer diagnosis is life-changing, and is a source of considerable psychological and emotional stress. Non - pathological sadness may be a normal response to a cancer diagnosis, however, stress beyond the coping mechanisms of patients may result in major ...

What percent of people have a depressive episode?

According to data from the 2017 National Survey on Drug Use and Health, 17.3 million adults in the United States—equaling 7.1% of all adults in the country—have experienced a major depressive episode in the past year. 11 million U.S. adults experienced an episode that resulted in severe impairment in the past year.

What percentage of people who are diagnosed with major depressive disorder will experience a recurrence following their first episode?

Many patients are at substantial risk of later recurrence, with 60% lifetime risk of recurrence after the first major depressive episode. As many as 70% of those with 2 MDEs have recurrences throughout their life, and 90% of those with three or more episodes will experience further recurrent episodes [2].Mar 19, 2020

What percentage of cancer patients usually suffer a mental illness?

Research shows that an average of 30% to 35% of cancer patients suffer from a psychiatric or neuropsychiatric disorder, with variance among the stages of cancer.Aug 13, 2021

Is depression common in cancer patients?

Depression is a common comorbidity in cancer cases, affecting >10% of patients. A cancer diagnosis is life-changing, and is a source of considerable psychological and emotional stress.Feb 9, 2015

What percentage of people recover from major depressive disorder?

Approximately 67 percent of people who had a major depressive episode said they received treatment. Around 72 percent of people who had a major depressive episode and a severe impairment said they received treatment.

When is MDD considered recurrent?

A recurrent depressive disorder is characterized by repeated episodes of depression without any history of independent episodes of mood elevation and increased energy or mania. There has been at least one previous episode lasting a minimum of two weeks and separated by the current episode of at least two months.

What percentage of cancer patients have depression?

Overview. Depression is a comorbid disabling syndrome that affects approximately 15% to 25% of cancer patients.Mar 4, 2022

How common are depression and anxiety in cancer patients?

Our findings showed that the prevalence of depressive and anxious symptomatology among cancer patients was 23.4% and 19.1–19.9%, respectively. Increased likelihood of depressive and anxious symptomatology was detected among patients in the inpatient setting (37.1% and 35.6–37.6%, respectively).Apr 15, 2021

Can cancer treatment affect mental health?

One in three people with cancer will experience a mental health problem such as depression or anxiety disorders before, during or after treatment.

Is depression common after cancer treatment?

Feeling low or depressed after treatment ends is common. Cancer survivors often experience worry, fear of recurrence, or periods of feeling down, for months or even years after treatment. Some people feel sad or depressed because of the changes that cancer has caused, or because they are frightened about the future.

Why do cancer patients experience depression?

Cancer patients often get depressed simply because having cancer can be a depressing experience.

Why do people with cancer get depressed?

As a cancer patient, you may develop clinical depression for a variety of reasons, including concerns over your diagnosis, the amount of pain you're experiencing, your family history of depression or other mental health issues, the number of outside stressors you're facing, and how much support you're getting from the ...Mar 6, 2017

What is Dr. Johnson's degree?

Dr. Johnson earned her master’s degree from The George Washington University and her doctoral degree from Seattle Pacific University. She provides counseling for adolescents and adults, and conducts psychological testing. Dr. Johnson specializes in geriatric mental health, grief and loss, adjustment to medical illness, post-abuse syndromes and depression. She is also a credentialed art therapist.

Is depression always obvious in oncology?

“The oncologist is focused on the disease process and medical treatment. Unless a patient is obviously distressed, their mental state often doesn’t come up. And depression isn’t always obvious, to the casual observer or even to the seasoned clinician in oncology practice, so it’s really important to proactively seek help for the best mental and physical health outcomes.”

Is it safe to face cancer alone?

But for some, cancer treatment can bring on depression, from mild to severe. Fortunately , there’s no need to face it alone.

How long does it take for a cancer patient to show depression?

To make a diagnosis of depression, the clinician confirms that these symptoms have lasted at least 2 weeks and are present on most days. The diagnosis of depression in people with cancer can be difficult because of the problems inherent in distinguishing biological or physical symptoms of depression from symptoms of illness or toxic side effects of treatment. This is particularly true of individuals who are receiving active treatment or those with advanced disease.

How many people are affected by depression?

Major depression affects approximately 25% of patients and has recognizable symptoms whose diagnosis and treatment are essential because they have an impact on quality of life. [ 19, 20] Depression is also an underdiagnosed disorder in the general population.

Why do we need to use screening tools for cancer?

Because of the common underrecognition and undertreatment of depression in people with cancer, screening tools can be used to prompt further assessment. [ 8] Among the physically ill, in general, instruments used to measure depression have not been shown to be more clinically useful than an interview and a thorough examination of mental status. Simply asking the patient whether he or she is depressed may improve the identification of depression.

What is the comorbid disabling syndrome?

Depression is a comorbid disabling syndrome that affects approximately 15% to 25% of cancer patients. [ 1 - 4] Depression is believed to affect men and women with cancer equally, and gender-related differences in prevalence and severity have not been adequately evaluated. [ 5] Individuals and families who face a diagnosis of cancer will experience varying levels of stress and emotional upset. Depression in patients with cancer not only affects the patients themselves but also has a major negative impact on their families.

Why are MAOIs used as last resort?

These medications can be highly effective, especially in the treatment of refractory depression and anxiety symptoms. However, MAOIs are primarily used as last resort because of their risk of serious side effects, multiple drug-drug interactions, and the significant dietary restrictions patients must adhere to when using these medications.

What are the two major classifications of depression?

There are two major classifications of symptoms for major depression: neurovegetative and emotional-cognitive. In cancer patients whose neurovegetative symptoms may be affected by the disease process or treatment, assessing the emotional-cognitive symptoms of their depression is likely to be more diagnostic and prevent false-positive results. Symptoms include the following:

Is bupropion a serotonin?

Bupropion is the only medication with this mechanism of action. It blocks the dopamine transporter while its primary metabolite, 6-hydroxybupropion, is a potent NE reuptake inhibitor. Bupropion may be more effective in the treatment of atypical depression (i.e., depression with fatigue and hypersomnia). It is a unique alternative to SSRIs and SNRIs for treating persons with depression and cancer, especially when depression is accompanied by fatigue. Unlike serotonergic antidepressants, bupropion is not associated with sexual dysfunction; therefore, it may be useful in treating patients who wish to remain sexually active and those who have experienced sexual dysfunction with other antidepressants.

How many people with cancer suffer from depression?

In fact, 15-25% of people diagnosed with cancer also suffer from depression. This is more than double that of the general population. Studies show that mental health and social well-being can affect the success of treatment. Depression is more than just the normal feelings of sadness.

What is the best treatment for depression?

Some common evidence based forms of treatment that are effective for depression are cognitive behavioral therapy, acceptance and commitment therapy and interpersonal therapy .

How to tell if you are depressed?

Distinguishing depression from normal sadness#N#Depression is more than just the normal feelings of sadness. Depression is a when an individual experiences at least one of the following symptoms for more than two weeks: 1 Feeling sad most of the time 2 Loss of pleasure and interest in activities you used to enjoy 3 Changes in eating and sleeping habits 4 Nervousness 5 Slow physical and mental responses 6 Unexplained tiredness 7 Feeling worthless 8 Feeling guilt for no reason 9 Decreased concentration ability 10 Thoughts of death or suicide

How to help someone with cancer?

Show your loved one that you truly care about his or her physical and emotional well-being. If you think you may suffer from depression, make time to get the help and support you need. After all, treating depression as soon as possible could help make your cancer journey a little less challenging.

Can antidepressants help cancer patients?

Anti-depressants are a common depression treatment prescribed for many cancer patients. And while they work great for some, they may not be the appropriate treatment for all cancer patients. There are also other proven methods that you may want to discuss with your doctor first. Here are a few:

Can you exercise after cancer?

The American Cancer Society recommends that you resume exercise as soon as possible after a cancer diagnosis, but this can be difficult for many cancer patients. So, talk with your health care provider about what's appropriate for you. Stick to routines: Following a routine can help you maintain a feeling of accomplishment and a sense of control, ...

What does it mean when you feel sad?

Feeling sad most of the time. Loss of pleasure and interest in activities you used to enjoy. Changes in eating and sleeping habits. Nervousness. Slow physical and mental responses. Unexplained tiredness. Feeling worthless. Feeling guilt for no reason. Decreased concentration ability.

What is the prevalence of depression?

Estimates of prevalence for depression vary from as low as 1% to greater than 50%. [2] This wide variation is due to several factors. Different diagnostic assessments, inclusion criteria the reported prevalence of depression. Mental health professionals typically use the Diagnostic and Statistical Manual of Mental Disorders (DSM IV) to diagnose depression. [3]

What are some ways to treat depression?

Other forms of therapy that have been used to treat depression include existential therapy, interpersonal therapy, and the therapeutic life narrative . [12] Addressing spirituality and meaning for patients with advanced cancer is a growing area of interest and research.

What happens after a bad news?

Immediately following bad news, most patients will experience a brief period of distress. Examples of such news would be the initial diagnosis of cancer, the news of cancer spread or relapse, or the news that care will be shifted from a focus on cure to a focus on comfort measures. During these periods, many of the symptoms of depression may be present such as sad mood, decreased appetite, poor sleep, difficulty concentrating, and uncertainty about the future. Patients may be preoccupied with thoughts of death and grieve for their current or anticipated losses. Patients may also experience a sense of helplessness and despair with debilitating symptoms such as pain, nausea/vomiting, and recurrent fevers that necessitate long hospital stays. These feelings are normal and may last for a few weeks depending on the medical and treatment circumstances.

Is depression a cancer diagnosis?

Depression is seen in many cancer patients. It is an especially importantissue in palliative care, as depression can be more common inpatients who are at the end of life. Accurate assessment and treatmentcan have a powerful impact on improving a patient's quality of life.This article reviews the definition and the differential diagnosis of depressionin cancer patients. It then focuses on some of the treatmentoptions available, including pharmacotherapy and psychotherapy.

How many people are affected by depression?

Who Is Affected by Depression? Major depressive disorder affects approximately 17.3 million American adults, or about 7.1% of the U.S. population age 18 and older, in a given year. (National Institute of Mental Health “Major Depression”, 2017) Major depressive disorder is more prevalent in women than in men.

Why do people stop taking depression medication?

Patients stop taking their medication too soon due to unacceptable side effects, financial factors, fears of addiction and/or short-term improvement of symptoms , leading them to believe that continuing treatment is unnecessary.

What is the leading cause of disability in the U.S.?

Neuropsychiatric disorders are the leading cause of disability in the U.S. with major depressive disorder being the most common (National Institute of Mental Health, “U.S. Leading Categories of Diseases/Disorders,” 2013) Mental Health (Depression, grief, and behavioral conduct) is the second leading workplace concern, following only family issues.

Is depression more prevalent in women than men?

Major depressive disorder is more prevalent in women than in men. (Journal of the American Medical Association, 2003; Jun 18; 289 (23): 3095-105) 1.9 million children, 3 – 17, have diagnosed depression. (Centers for Disease Control “Data and Statistics on Children’s Mental Health”, 2018)

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